Publication Search

Schizophrenia is a severe neuropsychiatric disorder that affects approximately 1% of the population, and is characterized by serious impairments in cognition, emotion and social functioning. The MTHFR gene is a key enzyme in folic acid metabolism, which plays an important role in biochemical processes in the body. One of the common genetic polymorphisms in MTHFR is C677T (rs1801133). Relevant articles were searched through an electronic database, Google Scholar, using the keywords “Relationship Between MTHFR C677T Gene and Schizophrenia”. MTHFR C677T can affect homocysteine metabolism, which in turn can affect the production of brain neurotransmitters such as dopamine and serotonin. An imbalance of these neurotransmitters has long been associated with schizophrenia. Environmental factors, such as stress, trauma, and social factors, also play an important role in the development of mental disorders, along with genetic factors such as MTHFR C677T.  

Diabetes mellitus is gathering disease metabolic with hyperglycemia caused by abnormalities in insulin secretion , insulin action , or both of them . Loss central type 2 diabetes is caused by insulin resistance in muscles and liver as well failure pancreatic beta cells . Purpose This research is to find out How extract ethanol leaf stalk palm affect the lipid values of diabetic rats. Type This research is a experimental . This research is divided into 6 groups with different treatment​ namely normal, control negative CMC-Na (0.5%), control positive glibenclamide (0.45mL), 125mg/kgBW extract , 250mg/kgBW extract and 500mg/kgBW extract . The results of the lipid parameter data were analyzed with SPSS 22 with level 95% confidence level Results study show extract ethanol dose 250 mg/kgBW and 500 mg/kgBW or more Lots lower level total cholesterol , triglycerides , and LDL as well increase HDL levels

West Sumatra, situated at the convergence of the Indo-Australian and Eurasian tectonic plates, experiences frequent earthquakes and aftershocks due to the complex geological setting. This study utilizes the Omori-Utsu method, a modified version of Omori’s law by seismologist Tokiji Utsu, to estimate aftershock duration. Data on aftershocks from significant earthquakes (magnitude ≥5.5M) between 2021 and 2023 were accessed through the BMKG earthquake catalog. The study finds that aftershock durations vary significantly depending on the earthquake's tectonic origin. The longest recorded aftershock duration occurred after the West Pasaman earthquake on February 22, 2022, lasting 21 days, while the shortest was one day following the Mentawai earthquake on September 11, 2022. These variations highlight the influence of tectonic structures on aftershock activity, with subduction zones exhibiting shorter decay times. This research provides critical insights into earthquake behavior, aiding in disaster preparedness and mitigation strategies for the West Sumatra region.    

This systematic literature review examines queue system simulation in hospitals across four key service areas: emergency departments, outpatient clinics, laboratories, and pharmacies. Following PRISMA methodology, 72 relevant studies (2015-2020) were analyzed to identify simulation models, software tools, performance parameters, and emerging trends. Findings reveal Discrete-Event Simulation dominance (59.7%), with increasing hybrid model adoption integrating System Dynamics and Agent-Based approaches. Emergency departments remain the primary application focus (52.8%), while Arena and AnyLogic emerged as predominant simulation platforms. Patient waiting time (91.7%) and resource utilization (77.8%) constitute the most evaluated performance metrics. Technological convergence trends demonstrate integration of real-time data analytics, machine learning, and digital twin concepts into traditional simulation frameworks. This review contributes methodological insights for optimizing hospital queueing systems while identifying research gaps in cross-departmental model interoperability and comprehensive value-based performance evaluation within contemporary healthcare systems.  

This study aims to analyze the level of attack by Macaca hecki on cultivated plants in Makarti Jaya Village, Pohuwato, Gorontalo. Agriculture is the main source of income for the local community, but the presence of Macaca hecki can threaten agricultural yields. The method used in this research is descriptive qualitative, with data collected through direct observation and interviews with farmers experiencing the attacks. The results indicate that corn (Zea mays) is the most consumed plant by Macaca hecki, followed by cocoa (Theobroma cacao) and several other types of fruit such as bananas and papayas. The high consumption rates of these cultivated plants negatively impact agricultural results, causing significant economic losses for farmers. Therefore, it is important to understand the attack patterns and the factors influencing the behavior of Macaca hecki. This research recommends the need for more effective protection strategies, such as the placement of physical barriers and diversification of plant types. Thus, it is hoped that this study can contribute to the management of conflicts between wildlife and agriculture, as well as enhance the economic sustainability of farming communities.

Mathematics plays a crucial role in everyday life, as it enhances students' abilities to absorb lessons more effectively and develop rational, critical, logical, analytical, and systematic thinking. This study employs the literature review method, which involves gathering relevant information from various sources to support the research topic. The author collects references from articles and journals using Google Scholar, an open-access database that simplifies the process of locating topic-specific materials. Difficulties faced by students in learning mathematics are not always due to a lack of mathematical knowledge. They may stem from other issues such as memory problems, difficulty in recalling mathematical problems, weak calculation skills, confusion with operational signs, or reversing numbers. Students with learning disabilities may particularly struggle with both mathematical reasoning and basic computation. Furthermore, mathematical learning difficulties are also associated with cognitive challenges, such as solving complex word problems and understanding numerical concepts. These learning difficulties often result from internal and external factors that hinder the brain’s ability to process, analyze, and retain mathematical information effectively.

This research aims to examine the influence of the school environment on the character development of elementary school students through the Systematic Literature Review (SLR) approach. The main focus is on the role of teachers and the condition of the school environment as important factors in the formation of students' character, especially amid the challenges of technological development and digitalization. Five relevant articles from 2021-2025 were systematically analyzed to obtain a comprehensive overview. The study findings show that a safe, inclusive and supportive school environment, as well as teachers who serve as positive role models, are helpful in creating values such as discipline, responsibility, honesty and social responsibility. However, this process still faces obstacles such as lack of teacher training, limited time in the curriculum, and high academic pressure. Therefore, collaboration between teachers, schools and parents is needed to create a learning environment that supports optimal character development.

This study aims to examine the role of ice breaking in improving students' learning focus at the beginning of the lesson, especially at the elementary school level. Icebreaking is a learning technique that aims to prepare students mentally and emotionally to receive lessons by creating a cheerful, relaxed, and enjoyable classroom atmosphere. This study investigated various literatures, including scientific journals and educational articles. The results of the study showed that turning ice was proven to be effective in improving students' concentration, enthusiasm, and social interaction. Ice breaking not only makes the atmosphere better, but can also improve student learning outcomes. Therefore, ice breaking can be used as a learning strategy to make elementary schools a good place to learn.

Education is one of the key aspects in developing high-quality human resources. Along with the advancement of time, teachers are expected to create effective learning media in the teaching and learning process. Learning media should also be adapted to students’ learning styles, such as visual, auditory, and kinesthetic.The purpose of this study is to develop and test the feasibility, practicality, and effectiveness of an IPS (Social Studies) magazine as a learning medium for Grade VIII students at SMPN 3 Kedungwaru Tulungagung. This research is a development study using the ADDIE R&D model. Data were collected through interviews, needs and learner characteristic analysis, feasibility and practicality questionnaires, as well as pretest and posttest results.The findings of this study show that the IPS magazine is highly feasible, with a feasibility percentage of 89.91% from material experts and 91.18% from media experts. The practicality results based on teacher questionnaires reached 94.87%, and student responses reached 88.62%, indicating that the IPS magazine is highly practical. The effectiveness of the media was proven through the Paired Sample Test, which showed a significance value of 0.000 < 0.05, indicating a difference in results before and after using the IPS magazine. Therefore, the IPS magazine is considered effective for use in the learning process.

Reading instruction is a fundamental skill that elementary school students must master. Storytelling as a teaching method has been widely implemented as an effective strategy to improve reading ability, as it integrates both cognitive and affective aspects of learning. This article discusses the implementation of the storytelling method in reading instruction, focusing on the use of supporting media such as picture books and digital storytelling. Based on a literature review from various recent journals and studies, it was found that storytelling can significantly enhance students' reading interest, text comprehension, and motivation. The success factors include teachers’ skills in delivering expressive storytelling and the availability of learning media. The article also addresses challenges faced and solutions to optimize the use of storytelling methods. The findings suggest that storytelling is highly potential as a primary strategy in reading instruction at the elementary level to build a strong literacy foundation from an early age.

Designing a user interface (UI) requires a deep understanding of how users think and interact with systems. This study explores the psychological and physiological aspects that influence user interaction with UI, such as perception, cognitive load, reaction time, and ergonomic factors. Through literature analysis and UI usability testing, this paper identifies design principles that enhance user experience by aligning interface structures with human capabilities. The results show that interfaces built with attention to psychological factors like user memory and attention span, as well as physiological aspects such as eye movement and hand positioning, significantly improve user satisfaction and efficiency.

Image processing is a branch of computer science that is growing rapidly and is widely used in various fields, including in security systems. Face identification is one of the main applications of image processing that aims to recognize and distinguish individual faces in a system. The methods used in face identification involve various techniques, such as facial feature detection, characteristic extraction, and classification using machine learning algorithms. This article discusses the application of image processing in a security system based on face identification and the technology used to improve the accuracy and reliability of the system. The results of the study show that the combination of deep learning algorithms with image pre-processing techniques can increase the success rate of face identification in security systems.

The purpose of this study is to determine the magnitude of the influence of inflation and interest rates on economic growth in Kupang City. The research used is quantitative research analyzed using the help of the SPSS (statistical package for the social sciences) time series data software program. The data collection for this study is secondary data from the East Nusa Tenggara Central Statistics Agency and Bank Indonesia in 2013-2022 in the form of quarters (time series) in NTT Province. The results of the study show that the results of the regression analysis, inflation does not have a significant effect on economic growth in Kupang City during the 2013-2022 period. The results of the partial test (t-test) show that changes in interest rates play a role in determining the dynamics of economic growth, where lower interest rates tend to encourage increased investment and consumption, while higher interest rates have the potential to restrain economic activity because they increase borrowing costs. The results of the simultaneous test (F test), inflation and interest rates have a significance value of less than 0.05, which means that both variables simultaneously play a role in determining economic growth. The coefficient of determination (R²) value of 35.11% indicates that only a small portion of the variation in economic growth can be explained by inflation and interest rates. The remaining 64.89% is influenced by other factors outside the model, such as investment levels, government spending, unemployment rates, fiscal policies, and external factors such as global commodity prices and national economic conditions.

The service activity is a continuation of the previous service activity, which is almost entering the final stage of efforts to commercialize Gulon Asri waste bank products. This service activity consists of material delivery activities and product making workshop activities along with recording video tutorials of the products being worked on. At this stage, waste bank women are taught to make video tutorials which can be used as a means of education about recycling fabric waste as well as a promotional medium for the products produced by the waste bank.

Hepatitis is an inflammation of the liver cells that can be caused by various factors, such as alcohol consumption, autoimmune disorders, drugs, or toxins. Viral infections, such as hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and hepatitis E virus (HEV). WHO estimates that by 2022, about 254 million people worldwide will be chronically infected with hepatitis B, with 1.2 million new infections occurring each year. In the same year, hepatitis B caused the deaths of about 1.1 million people, mostly due to cirrhosis and liver cancer. Hepatitis is very dangerous, therefore pregnant women really need to know about Hepatitis B disease and have positive behavior about Hepatitis B so that they can take precautions to prevent transmission to both the mother and the fetus. The purpose of this study was to determine the effect of using leaflets as educational media on increasing the knowledge and behavior of pregnant women about Hepatitis B in the Melintang Health Center Working Area. This type of research uses the Quasy Experimental Design method with pre-test and post test groups where observations are made twice, namely experiment and after experiment. Observations made before the experiment, namely observation 1 (O1) called the pre-test and after the experiment, namely observation 2 (O2) called the post test. Based on the results of the study, it was found that there was an effect of using leaflets as educational media on increasing knowledge (P = 0.000) and behavior (p = 0.000) of pregnant women about Hepatitis B in the Melintang Health Center Working Area in 2025. So it can be concluded that there is an effect of using leaflets as educational media on increasing the knowledge and behavior of pregnant women about Hepatitis B in the Melintang Health Center Working Area in 2025.

Hepatitis is an inflammation of the liver cells that can be caused by various factors, such as alcohol consumption, autoimmune disorders, drugs, or toxins. Viral infections, such as hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and hepatitis E virus (HEV). WHO estimates that by 2022, about 254 million people worldwide will be chronically infected with hepatitis B, with 1.2 million new infections occurring each year. In the same year, hepatitis B caused the deaths of about 1.1 million people, mostly due to cirrhosis and liver cancer. Hepatitis is very dangerous, therefore pregnant women really need to know about Hepatitis B disease and have positive behavior about Hepatitis B so that they can take precautions to prevent transmission to both the mother and the fetus. The purpose of this study was to determine the effect of using leaflets as educational media on increasing the knowledge and behavior of pregnant women about Hepatitis B in the Melintang Health Center Working Area. This type of research uses the Quasy Experimental Design method with pre-test and post test groups where observations are made twice, namely experiment and after experiment. Observations made before the experiment, namely observation 1 (O1) called the pre-test and after the experiment, namely observation 2 (O2) called the post test. Based on the results of the study, it was found that there was an effect of using leaflets as educational media on increasing knowledge (P = 0.000) and behavior (p = 0.000) of pregnant women about Hepatitis B in the Melintang Health Center Working Area in 2025. So it can be concluded that there is an effect of using leaflets as educational media on increasing the knowledge and behavior of pregnant women about Hepatitis B in the Melintang Health Center Working Area in 2025.

This study aims to analyze the perspectives of mathematics students on mixing aloe vera extract with weak acid solution for hair health and softness. The research method used is descriptive quantitative through the distribution of questionnaires to 43 mathematics students at Medan State University and other universities in North Sumatra. The questionnaire consists of 19 statements covering aspects of knowledge (12 items), environmental awareness (4 items), and psychomotor (4 items) with a Likert scale of 1-5. The results showed that the majority of respondents had good knowledge about the benefits of aloe vera for hair care (mean = 4.02), but the understanding of weak acid solution and its mechanism of action was still moderate (mean = 3.12). The environmental awareness aspect showed a high value (mean = 3.76) which reflects the tendency of students to choose natural products. Meanwhile, the psychomotor aspect showed a moderate value (mean = 3.44), which indicates the limitations of respondents' skills in applying hair care products optimally. This study found a positive correlation between knowledge about natural ingredients and the tendency to use natural-based products for hair care. The results of this study are expected to be the basis for developing hair care product formulations based on natural ingredients that suit the needs and preferences of students.

This study examines the transformation of advertising campaigns in the digital era and how social media has an impact on the meaning of consumers' social reality. Through a comprehensive literature review and case analysis, the study identified the mechanisms by which personalized advertising content on social media platforms alters the perception of an individual's social reality. The results showed that the targeting algorithm and filter bubble created a polarized space of information, resulting in a distorted representation of reality. This study contributes to an understanding of how digital advertising strategies affect the social construction of reality and proposes an ethical framework for advertising practitioners in the age of social media.

Community health services are the most important part of supporting community health. Puskesmas is a health institution that is very close to the community. Therefore, it is important to pay attention to supporting facilities and infrastructure in the medical records work unit such as work equipment, work procedures, work processes or systems, work environment, employee physiology and psychology so that medical records officers more productive at work. Based on observations made at the West Baktiya Community Health Center, it was found that the area of the medical records unit was 5 x 5 m2 with a ceiling height of 3 m, using a white ceramic floor, there were 6 windows, 1 door, 2 staff work desks and 3 cupboards for Save correspondence and other important documents. Lighting in the medical records unit room is 259 lux, noise is 53.3-62.0 dB, temperature in the medical records unit room is 33.1oC and humidity is 70%. In the medical records unit room there are no chemical substances in solid, liquid or gas form, and there are also no vectors or disease-carrying animals such as flies, mosquitoes, cockroaches and rats. The aim of this activity is to provide outreach regarding ergonomics in the medical records work unit at the West Baktiya Community Health Center. The implementation method consists of planning, implementation actions, evaluation and activity report preparation stages. The result of this service is that it can increase the knowledge of medical records officers and other healt

This study aims to explore the implementation of the Balanced Scorecard (BSC) through the digital system "MyCore" in measuring and improving employee performance at Bank BRI Unit Sokaraja Tengah. Using a descriptive qualitative approach, data were collected through semi-structured interviews with key informants, observations of work practices, and analysis of internal documents (performance reports, SOPs). Data analysis was carried out through data reduction, data presentation, and drawing conclusions with verification through source triangulation. The research findings indicate that the "MyCore" system integrates four BSC perspectives (finance, customer, internal business process, learning & growth) with specific performance indicators that affect incentives and career development. The financial and customer perspectives appear to have a strong emphasis, reflected in the direct impact on incentives and bonuses. The implementation of internal business processes is supported by standardization through MyCore and technology adoption. The importance of the learning and growth perspective is realized through regular training programs and bootcamp interventions for low-performing employees, which have proven effective in improving subsequent evaluation scores. In general, the implementation of the BSC via MyCore creates a structured, transparent, and adaptive assessment mechanism, encouraging productivity and professionalism. The implications of this study emphasize the importance of a transparent performance evaluation system that has a direct impact on career development and incentives, while also demonstrating the effectiveness of structured interventions in improving employee performance at the micro banking unit level.