Liver damage induced by hepatotoxic compounds such as N-acetyl-p-aminophenol (N-APAP) remains a significant global health concern. Hepatotoxicity caused by N-APAP, particularly in cases of overdose or prolonged use, can lead to a reduction in glutathione levels in the liver, resulting in oxidative stress and cellular damage. This condition contributes to an increased incidence of liver diseases, including toxic hepatitis and acute liver failure, which can lead to serious complications and even death. Although various pharmacological therapies, such as N-acetylcysteine (NAC), are available to address N-APAP-induced liver damage, limitations such as side effects, high costs, and variable efficacy have driven the search for safer and more affordable therapeutic alternatives. Therefore, research on natural hepatoprotective agents, such as extracts from the rhizomes of fingerroot (Boesenbergia rotunda), has become increasingly relevant in addressing this issue. The aim of this study was to evaluate the hepatoprotective potential of ethanol extract from fingerroot rhizomes (Boesenbergia rotunda) in protecting the liver from N-acetyl-p-aminophenol (N-APAP)-induced damage. Specifically, this research focuses on measuring glutathione levels as a key indicator of the liver's protective mechanism against oxidative stress. In this study, 30 male White rats were randomly divided into six groups, each consisting of five rats. All rats were orally administered the extract at predetermined doses for 10 consecutive days, except for the negative and positive control groups. On the 10th day, all groups (except group 1) were treated with paracetamol (800 mg/kg body weight) to induce liver damage. Twenty-four hours after induction, the rats were sacrificed and liver samples were collected. Glutathione levels were measured using the ELISA immunosorbent assay. Statistical analysis showed that administering the ethanol extract of Fingerroot rhizomes (EERTK) for 10 days prior to N-APAP induction significantly increased the average antioxidant enzyme GSH-Px levels in the liver homogenate of rats in the EERTK 250 mg/kg BW (43.36 ± 1.34 U/mg protein), EERTK 500 mg/kg BW (55.70 ± 2.15 U/mg protein), and 750 mg/kg BW (53.14 ± 2.57 U/mg protein) group compared to the negative control group (N-APAP 800 mg/kg BW), which had the lowest average antioxidant enzyme GSH-Px level (33.86 ± 3.52 U/mg protein).

Active, Creative, Innovative and Fun Learning Training (PAIKEM) is a strategy designed to improve the quality of learning through an approach that involves students actively and creatively. This article aims to describe the implementation and results of PAIKEM training for elementary school teachers in Padang Cermin District, Pesawaran Regency, Lampung. Training was carried out in three stages: preparation, implementation and evaluation. The methods used include simulations, group discussions, and practical assistance in class. The results of the training show an increase in teachers' understanding of PAIKEM principles, increased skills in applying creative methods, and increased student participation in the learning process. This training makes a significant contribution to the development of teacher competence and the quality of learning in elementary schools. To ensure the sustainability of the impact of training, continued assistance and synergy between schools, government and the education community is needed.

This study aims to analyze the relationship between learning readiness and the cognitive learning outcomes of fifth-grade students at MI Miftahul Ulum Tambakrejo Probolinggo. Learning readiness includes aspects of academic, physical, social, emotional, and cognitive skills, which are believed to influence learning outcomes. The research method used is quantitative with a correlational approach. The research sample consists of fifth-grade students, with data collected through questionnaires and learning outcome scores. Data analysis was conducted using Pearson and Spearman Rank correlation tests to measure the relationship between variables. The results indicate that although there is a positive relationship between learning readiness and learning outcomes in all subjects, the strength of this relationship is very weak. None of the correlations reached the required statistical significance to support the hypothesis of a meaningful relationship. Therefore, it can be concluded that H0 is accepted, meaning that there is no relationship between learning readiness and the cognitive learning outcomes of fifth-grade students at MI Miftahul Ulum Tambakrejo Probolinggo.

Globally, the prevalence of anemia in pregnant women in 2019 was 35.6%. The prevalence of anemia in developing countries is relatively high, such as Southeast Asia at 47.8%, compared to developed countries such as America at 18.9%. Efforts that can be made to prevent anemia include education, giving pregnant women biscuits and giving Fe tablets. This activity was carried out at the Bangun Rejo Village Health Center, Dusun VII, Tanjung Morawa District. The method used in this service is to provide education directly to pregnant women at the Bangun Rejo Village Health Center. The results of this activity were carried out in stages starting from preparation to evaluation. After implementing health education, giving pregnant women biscuits and giving Fe tablets, there was an increase in knowledge and consumption of Fe. Therefore, with this community service project, it is hoped that all pregnant women can increase awareness and Fulfill nutrition and balanced nutrition, regularly consume Fe tablets.

Penelitian ini dilakukan dengan tujuan memperoleh dan menemukan maksim-maksim dalam teori Grice, baik berupa penerapan maupun pelanggaran prinsp kerja sama sama teori Grice pada saat interaksi tawar-menawar antara penjual dan pembeli di Siring, Kota Banjarmasin. Penelitian ini berjenis kualitatif dengan menggunakan metode analisis deskriptif.  Metode analisis deskriptif dalam penelotian ini juga diperkuat dengan menggunakan pendekatan teori Grice. Cara kerja teori Grice menerapkan kerja maksim yang meliputi: maksim kualitas, maksim kuantitas, maksim relevansi dan maksim cara. Sumber data dalam penelitian ini ialah 4 orang penjual di Siring, Banjarmasin. Pengumpulan data dilakakukan dengan dua teknik, yakni teknik dokumentasi dan teknik catat. Proses penganalisisan data pada penelitian ini dilakukan dengan teknik analisis yang di sesuaikan dengan kajian analisis wacana oleh teori Grice. Dari hasil penelitian ditemukan penerapan dan pelanggaran dari maksim dalam kerja sama Grice. Data tersebut beruapa 10 bentuk penerapan dari maksim Grice  dan 3 pelanggaran maksim Grice.

Poverty in Indonesia is a complex problem involving various economic, social, and political factors. According to data from the Central Statistics Agency (BPS), the percentage of the poor population in Indonesia has decreased, but there are still millions of people living below the poverty line, especially in remote areas with higher poverty rates than urban areas. Empowerment of the dhuafa family is a strategic effort to improve the standard of living and welfare of economically disadvantaged community groups. This empowerment program aims to provide access to resources, education, skills training, and business capital. In a social context, the empowerment of the dhuafa family focuses not only on the economic aspect, but also on increasing the social and psychological capacity of individuals. The method used in the empowerment program is carried out in several stages, namely conducting interviews, observations, and documentation. With the efforts of the dhuafa family empowerment program, it is hoped that Indonesia can reduce poverty and improve the overall welfare of the community.

Social changes and lifestyles of the elderly and children at the Al-Hikmah orphanage are very different from before living in the orphanage and after living in the orphanage. The purpose of this study was to see the extent of social changes and lifestyles of the elderly and children at the Al-Hikmah orphanage. The method used in this study is capacity building which aims to increase individual or group understanding of the problems they face while equipping them with ways to overcome them independently. The results of the analysis showed that there was a significant increase in the knowledge of the elderly about cholesterol and hypertension. Before the intervention, 40% of the elderly still did not understand the impact of cholesterol and hypertension. The results of the analysis showed that there was a significant increase in children's knowledge about healthy lifestyles. As many as 30% of children at the Al-Hikmah orphanage still did not understand what a healthy lifestyle was.

Village potential greatly influences the community's economy. Management of superior village products from various sectors will influence and provide beneficial impacts for the village itself. Kemlagi Village, Mojokerto Regency has various products in the tourism sub-sector based on culture/local wisdom, agriculture and livestock whose quality is not inferior to other potential villages. To increase the potential of the village area, it is necessary to increase the village branding of any potential sub-sectors that the village has. Therefore, it is carried out in several stages; field observations, interviews, documentation and data analysis related to village economic potential. With the result that the lack of public understanding of product marketing and promotion is the main obstacle in developing local potential. The community responded to this by providing suggestions and ideas to each other so that their village could develop. Apart from that, this activity also introduces the use of social media to help branding and promotion of villages and UMKM products in Kemlagi Village, Mojokerto Regency.

This research aims to examine the influence of convenience, business expectations, and social factors on interest in using accounting information systems. The population in this study were employees of Bank Syariah Indonesia in Jayapura. The questionnaire data that can be processed has been filled in by 87 respondents. The data analysis technique uses multiple regression analysis. The research results show that convenience, business expectations, and social factors have a significant positive effect on the interest of Bank Syariah Indonesia employees in Jayapura City in using accounting information systems.

This study aims to analyze the influence of e-money usage and financial literacy on the consumption behavior of accounting students in Batam City. E-money as a digital payment method has become increasingly popular among the younger generation, while financial literacy plays an important role in effective personal financial management. The study uses primary data collected from questionnaires distributed to 97 accounting students in several universities in Batam, as well as secondary data from interviews with 10 accounting students regarding e-money and financial literacy. The results show a positive correlation between high financial literacy and wise financial management, which in turn influences students' consumption behavior. Additionally, the use of e-money plays a significant role in facilitating transactions and changing consumption patterns. Simultaneously, all three variables have a significant impact with a coefficient of determination (R²) of 38.5%. The findings are expected to provide insights for relevant stakeholders in designing more effective financial education programs and promoting the use of e-money among students.