Indonesia's biodiversity holds great potential for drug development, including through the use of traditional medicinal plants such as tapak liman (Elephantopus scaber L.), suruhan (Peperomia pellucida L. Kunth), and temu ireng (Curcuma aeruginosa Roxb.). These plants have been used in traditional medicine and are known to contain bioactive compounds with potential anticancer properties. Tapak liman contains compounds capable of inducing apoptosis in cancer cells. Suruhan is known to have cytotoxic and immunomodulatory effects, while temu ireng contains compounds with antioxidant and anticancer activity. This study aims to identify and quantify the bioactive compounds in these three plants using Gas Chromatography-Mass Spectrometry (GC-MS) and to explore their therapeutic potential in cancer treatment. The results of GC-MS analysis successfully identified six main compounds that have potential as anticancer agents, namely Phytol, Caryophyllene, Apiol, Germacrone, Germacrene B, and one additional compound. Temu ireng contains Germacrone, Germacrene B, and Caryophyllene, while suruhan contains Caryophyllene, Apiol, and Phytol. Meanwhile, tapak liman shows the presence of bioactive compounds that support cytotoxic activity. The focus of this study is on the interaction of bioactive compounds with the Bcl-2 protein, which plays a role in inhibiting apoptosis in cancer cells. Additionally, molecular analysis revealed that Germacrone, Germacrene B, Caryophyllene, and Apiol can also bind to the p53 protein, known as a guardian of the genome and a trigger for apoptosis. These findings suggest that the three plants have high potential as natural sources of anticancer agents. Further in vitro and in vivo studies are recommended to test the biological efficacy of these compounds in the context of cancer therapy, thereby bridging traditional knowledge with modern scientific approaches in the development of natural-based medications.

Community participation refers to the active involvement of citizens in various stages of the development process, especially at the village level. A concrete example of community participation can be seen in the case study of Bendhung Lepen, located in Mrican Village, Yogyakarta. Bendhung Lepen is an irrigation canal that stems from the Gajah Wong River. Before its revitalization, the area faced numerous environmental problems, primarily due to household waste and pollution that contaminated the waterway and negatively affected the environment and public health. In response to these issues, local residents, along with relevant stakeholders, initiated an environmental conservation program. The main goal of this initiative was to restore the ecological function of Bendhung Lepen and transform it into a clean, green, and beneficial public space for the community. This study aims to measure the level of community participation in the environmental conservation program. Data collection methods included questionnaires for quantitative analysis and in-depth interviews for qualitative insights into community involvement. The results of the study show that community members were actively involved in various phases of the program, including planning, implementation, and evaluation. Stakeholders involved in the program included community leaders, youth groups, environmental organizations, and village officials. The forms of participation extended beyond voicing aspirations to contributing labor (through mutual cooperation) and materials (such as donations or supplies). According to Arnstein’s ladder of participation, the level of community participation in this conservation program falls under the category of "delegated power," which represents a high degree of participation. This means that the community was not merely involved as passive participants but was given real authority in decision-making and program management. These findings indicate that genuine and sustained community involvement plays a crucial role in the success of local environmental conservation efforts.

This community service activity aimed to provide guidance and capacity building for micro, small, and medium enterprises (MSMEs), specifically chicken satay vendors operating in the parking area of Taman Anggrek Mall, Jakarta. These culinary MSMEs have strong potential due to their strategic location, which attracts high foot traffic. However, many of these business owners still face challenges in managing and developing their businesses, particularly in terms of managerial skills, financial record-keeping, and marketing strategies. Therefore, this program was designed to enhance their business competitiveness by improving their managerial abilities, introducing simple bookkeeping practices, and promoting the use of digital platforms for marketing. The implementation of the program began with an initial observation to identify the specific needs and challenges faced by the MSME actors. This was followed by interactive training sessions covering topics such as the importance of basic financial management, how to create simple financial reports, and effective yet low-cost digital marketing strategies. In addition to the training, the team also provided intensive one-on-one mentoring to ensure that participants could apply the materials in their daily business operations. The outcomes of the program showed positive developments. The MSME participants began to recognize the importance of keeping financial records as a basis for making business decisions. They were also able to identify internal management issues such as inventory control and business planning. In terms of marketing, most of the vendors have started using digital platforms like WhatsApp Business and Instagram to promote their products, allowing them to reach a wider audience.It is expected that this community engagement initiative will continue and serve as a model for similar training programs targeting culinary MSMEs in other busy urban areas. Such efforts are essential to developing more independent, professional, and competitive MSMEs in the digital era.

Crystal guava farmers in Cikarawang Village, Bogor Regency, face challenges in accessing information related to proper cultivation techniques, from seedling to harvest. The lack of access to valid and easy-to-understand sources of information causes farmers to have difficulty in dealing with various cultivation problems, such as pests, diseases, and effective fertilization. In response to these problems, an innovation was developed in the form of a digital agricultural website containing a complete summary of material on crystal guava cultivation. This website is designed to be easily accessible to farmers and functions as a practical and efficient one-way information media. In addition, this website is also equipped with an online community feature through a discussion group connected to expert mentors in the field of crystal guava cultivation. This feature allows farmers to share experiences, discuss, and obtain direct guidance from experts. This innovation is expected to improve farmers' knowledge, skills, and independence in managing crystal guava cultivation sustainably.

The digital era has significantly transformed the external environment of educational institutions, demanding swift, strategic, and innovative adaptation to remain relevant to societal needs. Key external factors such as rapid technological advancement, evolving government policies, globalization of education, and disparities in digital access pose substantial challenges to maintaining educational quality. Institutions that fail to adapt risk falling behind in both learning quality and graduate competitiveness. This study aims to explore effective adaptation strategies for educational institutions amid these digital dynamics. Employing a literature review with a descriptive qualitative approach, the research analyzes various sources discussing educational responses to technological and policy developments. The findings highlight essential strategies such as integrating a technology-based curriculum, adopting digital learning platforms, enhancing educators’ digital literacy, and improving technological infrastructure to support distance learning. Strengthening institutional capacity to manage digital transformation also becomes a vital component. Furthermore, collaboration with stakeholders—government, private sector, and society—is vital for building an inclusive educational ecosystem. Community involvement and industry partnerships can support resource development and ensure curriculum relevance. However, implementation barriers remain, including insufficient teacher training in digital pedagogy, unequal internet access in remote areas, and limited funding. These issues necessitate digital-oriented education policy evaluations and stronger regulatory frameworks to bridge the digital divide. The study concludes that successful adaptation goes beyond merely adopting technology. Sustainable transformation also depends on continuous evaluation and support systems. By implementing the right strategies and addressing key obstacles, educational institutions can effectively navigate digital challenges and foster sustainable, future-oriented learning environments aligned with contemporary demands.

the development of technology requires the world of education to face the optimal use of digital media. This article is quoted to describe the process of making and utilizing WordPress -based digital bulletin board in SMAN 1 2 × 11 six environment as a medium of expression, information, and memorization of digital literacy of students. The method of implementing activities includes training in the use of WordPress, the formation of an editorial team, technical assistance in making digital bulletin board, content of content publications. The results show that students are able to create a wordpress account, choose the appropriate theme, lock the content of the article, and distribute digital bulletin links online. In addition, this activity increases the ability of student digital literacy and encourages collaboration between students in managing school information. Digital Mading is proven to be an innovative and effective learning medium in fostering the 21st century skills. This article is expected to be a reference for other educators in integrating digital technology in school literacy activities.

Adolescence is an important period in the formation of a person's personality, where individuals tend to be easily influenced by the social environment including associations. Unhealthy associations have the potential to cause various problems such as peer pressure, low self-confidence, and the emergence of deviant behavior. This service activity aims to increase the awareness and understanding of Muhammadiyah 6 Samarinda Junior High School students regarding the importance of applying ethics in society through the provision of classical guidance services. The activity, which carries the theme "Ethics in Society: Fun Friends Are Not Toxic", was held for three days on May 14-16, 2025, with three main sessions lasting 150 minutes every day. The material provided includes the introduction of the concept of social ethics, identification of healthy and unhealthy associations, ethical values in Islam, and ethics of behavior on social media. Through participatory and reflective methods, students are invited to actively discuss, conduct social simulations, and reflect on the values learned. The results of the evaluation showed an increase in student understanding, changes in social attitudes, and openness in communicating with guidance and counseling teachers.

This article examines the role of literature as a medium for social criticism. Literature is not merely a collection of beautiful words; it also functions to convey emotions, ideas, and criticism regarding social issues. Literature can portray societal conditions and various issues veiled in public discourse, fostering debate, reflection, and acting as a catalyst for social change. This article specifically analyzes W.S. Rendra's poem "Orang Kepanasan" (People Overheated) as a clear example of how literature can serve as a medium for social critique.Using a descriptive qualitative approach and documentation method, this study identifies various forms of injustice, including social inequality, legal injustice, and political injustice, as represented in the poem. Rendra employs symbolism and precise language to express public dissatisfaction, even if not explicitly. The per-stanza analysis of the poem reveals sharp criticism that depicts the limited lives of the marginalized confronting luxury and power. Thus, this article affirms that literary works have a cumulative role in shaping public opinion, fostering critical thinking about surrounding circumstances, and disseminating critical ideas, even if change does not occur instantaneously.
 
 

This research aims to analyze the effectiveness of stimulating creativity in children aged 4-5 years through the use of picture story books. Creativity is an important key in developing the potential of early childhood. This creativity can be increased through interesting and interactive learning media. The research method used is classroom action research with qualitative research. Data was obtained through observation and interviews with one of the teachers who teaches at an early childhood education institution. The research results show that the use of picture story books in learning can stimulate children's imagination, creative thinking abilities, encourage children's curiosity, and enrich their vocabulary. Apart from that, the activity of reading together with the assistance of a teacher or parent has a positive impact on children's social interactions. Thus, picture story books can be an effective alternative medium for stimulating the creativity of early childhood children aged 4-5 years.

The folktale "Bawang Putih dan Bawang Merah" is one of the oral cultural heritages that is widespread in the Nusantara region, especially in the Indonesian and Malay language traditions. This study analyzes the narrative structure and moral values ??contained in the story through a structural and hermeneutic approach. The analysis shows that this story has a distinctive structure with a pattern of family conflict, heroic journey, and moral resolution that reflects the traditional value system of the Malay-Indonesian community.