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Background: Diabetes Mellitus (DM) is a disease that cannot be completely cured or cannot even be completely cured. The vile shard plant is empirically used by the community to treat diabetes (DM). This study aims to conduct phytochemical screening and test the activity of 96% ethanol extract of kejibeling leaves (Strobilanthes crispus (L.) Bl.) as a herbal antidiabetic in male white mice (Mus musculus) with alloxan induction. Method: This research is an experimental laboratory research with a true experimental posttest control design using a completely randomized design (CRD) with 5 treatments and 5 replications. Treatment P1 (without treatment) as normal control (N), P2 as positive control (+), P3 as negative control (-), P4 kejibeling leaf extract 250 mg/kg BW, P5 kejibeling leaf extract 500 mg/kg BW. Result:The results of phytochemical screening showed the presence of alkaloids, flavonoids, tannins, saponins, terpenoids and steroids. SPSS results show that the data is normally distributed (p>0.05) and homogeneous (p>0.05). The results of the ANOVA on the treatment of giving keji beling leaf extract 250 mg/Kg BW showed a sig. 0.393 (p>0.05) and treatment of 500 mg/Kg BW obtained a sig value. 0.517 (p>0.05). Conclusion:The conclusion from the research results shows that administering doses of 250 mg/kg BW and 500 mg/kg BW of keji beling leaf extract can reduce blood sugar levels in mice. It is hoped that the results of this research will be useful for the community as an antidiabetic therapy using kejibeling leaves (Strobilanthes crispus (L.) Bl.).

This study aims to analyze the characteristics of the soil at PIT North with two highwall and lowwall locations at PT Karya Putra Borneo, Kutai Kartanegara Regency, East Kalimantan Province. The research method was carried out by collecting primary data from the results of field tests using the sondir method with the Cone Penetration Test(CPT) tool and laboratory tests using physical properties, specific gravity, grain size, soil consistency, and consolidation tests, as well as secondary data from the results of literature studies. The parameters analyzed for soil characteristics include the sondir cone resistance (qc) value, grain size fraction distribution, soil plasticity index, and the rate of land subsidence through consolidation. The results showed that at PIT North the highwall area had a qc value of 5.6 Mpa, Fr 0.2%, IP 8.06%, Cc 1, a large rate of land subsidence of 3.3 mm with a settlement period of 4 years. In the lowwall area with a qc value of 10.31 Mpa, Fr 0.16%, IP 6.39%, Cc 0.535, the rate of settlement was 4.4 mm with a settlement period of 3 years. From these results, it is concluded that the soil at the highwall and lowwall locations has different compressibility, seeing the different soil Cc values and the soil plasticity index that affect the compressibility level of the soil and the value of the land settlement rate.

This research aims to examine the implementation of group guidance services in developing a positive self-concept among students who actively use social media. The rapid development of digital technology has positioned social media as a space for self-expression, yet uncontrolled use often leads to negative social comparisons that distort adolescents' self-perception. This study employed a qualitative approach with a descriptive design. Data were collected through deep interviews, observations, and documentation involving students at IAKN Toraja. The findings indicate that group guidance services, conducted through the stages of formation, transition, core activity, and termination, significantly contribute to the formation of a positive self-concept. There is a notable improvement in students' self-confidence, self-acceptance, and self-control regarding social media usage. The group dynamics provide a supportive social laboratory for students to share experiences and receive constructive feedback, allowing them to reconstruct a more realistic and healthy self-image. The implication of this study suggests that group guidance can be an effective intervention for school counselors to mitigate the negative psychological impacts of digital interaction and foster digital literacy among students.  

The computer laboratory is an essential facility in higher education that requires efficient management of usage and environmental conditions to support the teaching and learning process. However, laboratory management at the Kalimantan Business and Technology Institute is still carried out manually, including scheduling, room condition monitoring, and report creation, which is prone to errors and time-consuming. This study aims to develop an Internet of Things (IoT)-based laboratory monitoring system prototype to improve the effectiveness of computer laboratory management. The approach used is Research and Development (R&D) with a prototype development model, allowing for design adjustments based on user feedback iteratively. Data were collected through observations, interviews, and document studies related to laboratory conditions and analyzed to determine the main system features, such as temperature and humidity monitoring, scheduling, and report generation. The results of the study show that the developed prototype can structure the laboratory workflow, provide real-time monitoring, facilitate schedule management, and simplify report preparation. This prototype is expected to serve as a foundation for developing a more comprehensive application, improving data accuracy, time efficiency, and the quality of laboratory management.

The computer laboratory is an essential facility in higher education that requires efficient management of usage and environmental conditions to support the teaching and learning process. However, laboratory management at the Kalimantan Business and Technology Institute is still carried out manually, including scheduling, room condition monitoring, and report creation, which is prone to errors and time-consuming. This study aims to develop an Internet of Things (IoT)-based laboratory monitoring system prototype to improve the effectiveness of computer laboratory management. The approach used is Research and Development (R&D) with a prototype development model, allowing for design adjustments based on user feedback iteratively. Data were collected through observations, interviews, and document studies related to laboratory conditions and analyzed to determine the main system features, such as temperature and humidity monitoring, scheduling, and report generation. The results of the study show that the developed prototype can structure the laboratory workflow, provide real-time monitoring, facilitate schedule management, and simplify report preparation. This prototype is expected to serve as a foundation for developing a more comprehensive application, improving data accuracy, time efficiency, and the quality of laboratory management.

The stability of disposal slopes is a critical aspect of open-pit mining operations because it directly affects operational safety and the continuity of overburden dumping activities. Disposal areas composed of overburden materials generally exhibit heterogeneous characteristics, particularly when soft materials such as mud are present, which can significantly reduce slope stability. Therefore, a comprehensive slope stability evaluation is required prior to further disposal development. This study aims to assess the stability condition of a disposal slope under initial conditions, evaluate the influence of material conditions, and analyze the effectiveness of counterweight application in improving both the safety factor and disposal capacity. The research methodology involved the collection of primary and secondary data, including slope geometry, lithological conditions, and the physical and mechanical properties of disposal materials obtained from laboratory testing and company technical data. Slope stability analysis was performed using the limit equilibrium method with the assistance of geotechnical software, taking into account groundwater conditions and operational loading. The analysis results indicate that the initial disposal condition yielded a safety factor of 0.718, indicating an unstable slope condition. After simulating the removal of mud material, the safety factor increased to 0.907 but remained below acceptable stability criteria. The application of a counterweight significantly improved slope stability, resulting in a safety factor of 1.498. Further optimization through slope geometry redesign produced a final safety factor of 1.101, which satisfies the requirements stipulated in KEPMEN ESDM No. 1827 K/30/MEM/2018. Additionally, the redesign increased the disposal capacity from 119,507,864.23 LCM to 119,682,378.22 LCM, representing an increase of 174,513.99 LCM. These results demonstrate that counterweight application combined with geometric optimization is effective in enhancing both slope stability and disposal capacity.

Elsheskin is a local skincare brand from Yogyakarta, which is under the auspices of PT Elshe Estetika Nusantara. In October 2024, it was circulated that Elsheskin had overclaimed the content of skincare products, because the retinol content in Elsheskin's retinol rejuvenating night serum product was proven to be inconsistent with laboratory test results. This overclaim case has damaged Elsheskin's image. The purpose of this study is to measure Elsheskin's crisis communication in dealing with the case of overclaiming the content of skincare products, Elsheskin's image after conducting crisis communication and how much influence the crisis communication of the case of overclaiming the content of skincare products has on Elsheskin's image. The theory used is the crisis communication theory (Coombs, 2019) which consists of the pre-crisis stage, the crisis event stage and the post-crisis stage. This study also uses the Image theory (Boulding, 2007) which consists of knowledge, feelings, values ​​and beliefs. The method used in this study is a quantitative approach with a survey method and a simple random sampling technique by distributing paper questionnaires to 80 respondents selected according to the characteristics of the study. From the results of calculations and data processing using the SPSS 25 application, namely: a) Elsheskin has carried out crisis communication well in accordance with crisis communication theory. b) Elsheskin has succeeded in restoring its image due to the overclaim case. c) There is an influence of crisis communication in the case of overclaiming skincare product content on Elsheskin's image of 59.2%.

This study aims to describe and analyze the strengthening of eight basic teaching skills in prospective Islamic Religious Education (PAI) teachers at the University of Qur'anic Sciences (UNSIQ) through the Micro Teaching course. The eight skills include questioning, reinforcement, variation, explaining, opening and closing lessons, guiding small group discussions, class management, and small group/individual teaching. This study uses a descriptive qualitative approach. Data were collected over one month through participatory observation in the Micro Teaching Laboratory, documentation, and in-depth interviews with 12 informants consisting of 2 lecturers and 10 PAI students. The results showed that Micro Teaching learning significantly increased students' self-confidence and pedagogical competence. Specific findings indicate the integration of Qur'anic values in teaching practices, such as the use of kalimah thayyibah as a form of verbal reinforcement skills. Nevertheless, classroom management remains the most challenging aspect for students. This study concludes that intensive simulation and continuous feedback are the main keys to producing professional PAI teacher candidates with Qur'anic character.

The availability of human resources (HR) in hospitals is a key factor in ensuring quality healthcare services. A type C general hospital in Medan faces challenges in terms of limited health personnel in several service units. The Workload Indicators of Staffing Need (WISN) method by WHO is applied to calculate staffing requirements based on actual workload. This study aimed to analyze the workload and HR needs of a type C general hospital in Medan using the WISN method. A quantitative descriptive study with a WISN approach. Data were obtained from hospital management reports including patient visits, bed occupancy rate (BOR), and staff distribution across main units. Analysis was carried out by calculating available working time, workload standards, allowance standards, and HR needs per unit. The analysis indicated shortages of personnel in several units: inpatient nurses (−20), anesthetists (−2), pharmacists (−1), laboratory analysts (−5), radiographers (−5), and medical records staff (−6). Some units had surplus staff, such as maternity (+8). The type C general hospital in Medan continues to face HR shortages in critical service units. Workload-based HR planning using the WISN method is crucial to support effective recruitment and staff redistribution.

The decline in seed quality due to storage beyond the shelf life is a major problem in rice cultivation. One effort that can be made to improve seed viability is through invigoration techniques using natural ingredients, such as bean sprout extract (Phaseolus radiatus), which contains growth hormones. This study aims to analyze the effect of bean sprout extract on the viability of Ciherang rice seeds that have exceeded their shelf life and to determine the best treatment. The study was conducted from August to November 2024 at the Biology Laboratory of the UPTD Seed Center, Supervision and Certification of Agricultural Seeds of Gorontalo Province. The study used a two-factor Randomized Block Design (RBD) with bean sprout age (3, 5, and 7 days after sowing) and bean sprout extract concentration (20 g/L, 40 g/L, and 60 g/L) as factors, with four replications. The parameters observed included germination rate, maximum growth potential, and sprout length. The data were analyzed using ANOVA and DMRT post-hoc test at a 5% level. The results showed that bean sprout extract had a significant effect on all observed parameters. The treatment of 5-day-old bean sprouts with a concentration of 20 g/L gave the best results with a germination rate of 95.5%, maximum growth potential of 98.5%, and the highest sprout length. Sprout extract has the potential to be used as a natural alternative to improve the quality of rice seeds that have passed their storage period.

Formalin is a hazardous chemical that is banned from use in food, but is still found in imported fruit. Traders have an important role in preventing the circulation of food with formaldehyde, so the knowledge of traders about the dangers of formaldehyde needs to be studied. Objective: This study aims to determine the knowledge of traders and formalin content in imported fruit sold in X Market, Palembang City in 2025. Methods: This study used a quantitative approach with a descriptive design. The population in this study were all imported fruit traders in X Market totaling 9 people who served as respondents. The fruit samples tested were 24 samples consisting of apples, pears, and grapes. Data were collected through questionnaires and laboratory tests using formalin test kit. Results: The results showed that all traders (100%) had a good level of knowledge about formalin. Of the 24 fruit samples tested, 21 samples (87.5%) did not contain formalin and 3 samples (12.5%) showed positive results, all of which were from grapes. Conclusion: The majority of traders had good knowledge about formaldehyde, but formaldehyde was still found in some imported fruits, especially grapes.

Atherosclerosis, as the leading cause of cardiovascular disease, can be triggered by a high-fat diet that causes hyperlipidemia. Fern leaves (Diplazium esculentum) contain various bioactive compounds (alkaloids, phenols, flavonoids, terpenoids) with antioxidant and anti-inflammatory potential, which are suspected to inhibit the formation of atherosclerotic lesions. This study aims to determine the effect of administering fern leaf extract on the histopathological features of the aorta in Wistar rats induced by a high-fat diet. This laboratory experimental study used 25 male Wistar rats divided into five groups: (A) normal control, (B) negative control (high-fat diet), (C) positive control (high-fat diet + simvastatin), (D) treatment I (high-fat diet + fern leaf extract 600 mg/kgBW), and (E) treatment II (high-fat diet + fern leaf extract 1200 mg/kgBW). The treatment was administered for 21 days. On the 22nd day, the aorta was taken and processed into histopathological preparations using Hematoxylin-Eosin (H&E) staining. The number of foam cells was counted at 400x magnification. Data were analyzed using the One-Way ANOVA test followed by the Tukey test. There were differences in the number of foam cells between groups. The post-hoc test showed a significant difference between group B (high-fat diet) and all other groups (p<0.001). There was no significant difference between group E (extract 1200 mg/kgBW) and group C (simvastatin) (p=0.783), nor between group D (extract 600 mg/kgBW) and group C (p=0.075). Fern leaf extract (Diplazium esculentum) is able to reduce the number of foam cells in the aorta of Wistar rats induced by a high-fat diet.

Radiographic examination plays a crucial role in visualizing internal body structures for diagnostic purposes. One of the radiographic assessments frequently performed is the Acromioclavicular (AC) joint projection, which is used to evaluate abnormalities such as joint widening, subluxation, and dislocation. This study aimed to compare the image quality of the AC joint using the Anteroposterior (AP) projection with a 3-kg load and without load. The study was conducted in the Radiology Laboratory of STIKES Borneo Nusantara using a conventional X-ray system with a quantitative descriptive case-study approach. Data were collected through observation and questionnaires administered to 10 research subjects, including radiographers and patient participants. The findings demonstrated that the AP projection with a 3-kg load produced clearer visualization of the AC joint, particularly in widening of the joint space and separation between the humeral head and glenoid cavity. The average image quality score using load was 3.5 (good), compared with 2.9 (poor) for the projection without load. The study concludes that applying a 3-kg load improves anatomical visualization of the AC joint and is recommended for cooperative patients to enhance diagnostic accuracy.

Behind the success of the Free Nutritious Meal Program (MBG), there are several problems related to the health factors of the program targets, namely, there are several cases of allergies that occur in schools, inadequate understanding of allergen management owned by food processing vendors, and the high cost of laboratory tests and the process that takes a long time. So, to overcome these problems, an application is proposed that can help detect allergens in food products using data mining and machine learning approaches. SVM and AdaBoost algorithms each have advantages that can be used to help build an optimal allergen detection model. This research uses a cross-validation model validation method with a value of K = 10 to help improve the performance of the model built. In this study, from the entire fold, an average accuracy value of 98.74% was obtained. To evaluate the model built, this research has also conducted several new data inputs, and in each new data input, the accuracy value is obtained above 99%. This indicates that the model built, namely the combination of SVM and AdaBoost algorithms with the cross-validation model validation method, produces high accuracy, so this model can greatly assist the allergen detection process in food products.

Modern society faces multidimensional complexities, ranging from spiritual crises and technological disruption to social inequality. Muslims, with their theological and intellectual capital, are often perceived as suboptimal in responding to these challenges contextually and applicatively. This article aims to analyze the fundamental problems faced by Muslims in formulating answers to the problems of modern society and to explore the strategic role of Islamic higher education institutions, specifically the Muhammadiyah University of Malaysia (UMAM), in bridging this gap. This research uses a qualitative approach with a case study method at UMAM. Data was collected through literature study, observation, and structured interviews with academics and policymakers at UMAM. The findings indicate that the main problems lie in: (1) the dichotomy between naqli and aqli sciences, (2) a static approach to religious texts, and (3) a lack of integrative and innovative solution models. UMAM strives to address these issues through three main strategies: integration of knowledge in the curriculum, problem-based research, and empowering community engagement. This article concludes that UMAM has the potential to become a model social laboratory of Islam that combines the Muhammadiyah renewal ethos with the Malaysian socio-cultural context to produce relevant, humanist, and rahmatan lil 'alamin solutions.

This study aims to analyze hematocrit values ​​using a micro method with capillary blood samples in pregnant women with anemia at the Sidodadi Kisaran Barat Community Health Center. This study is a descriptive study with a cross-sectional approach involving 15 pregnant women as respondents. Data collection was carried out through hematocrit laboratory examinations and data collection of respondent characteristics. The results showed that 60% of respondents had hematocrit levels below normal values, while 40% of respondents had hematocrit levels within normal limits. Low hematocrit levels in pregnant women are influenced by several factors, including age, education level, employment status, and level of knowledge about anemia during pregnancy. This condition has the potential to increase the risk of pregnancy complications if not optimally managed. Therefore, it is recommended that health workers continue to increase educational efforts regarding anemia prevention, the importance of regular pregnancy check-ups, and encourage pregnant women to maintain a balanced nutritional consumption pattern and adequate iron intake to support maternal and fetal health.

Nicotine is the main chemical substance found in cigarettes and has toxic and addictive properties. Exposure to nicotine in active smokers can cause various health problems, including respiratory and cardiovascular disorders and dependence. The prevalence of active smokers in RT 08 RW 05, Duren Jaya Village, East Bekasi Subdistrict is quite high. However, data on nicotine levels in the bodies of active smokers remain very limited. This study aims to determine the nicotine levels in active smokers in Duren Jaya Village, RT 08 RW 05, Bekasi Timur District, using urine samples. The research method employs a descriptive design with a cross-sectional approach. Urine samples were collected from 30 male active smokers aged over 35 years who had smoked for at least 15 years. Nicotine levels were measured at the Jakarta Regional Health Laboratory using Gas Chromatography-Mass Spectrometry (GC-MS). Data were analyzed descriptively using SPSS version 22. The study included 30 male respondents (100%) with an average age of 41 years. The analysis results showed nicotine levels ranging from 59.908 ng/mLto 459.941 ng/mL, with the majority of respondents falling into the category of active smokers based on the biological threshold for nicotine levels. It can be concluded that the results obtained indicate that these levels correspond to active smokers using light tobacco.

This study aims to determine the optimal pectinase enzyme concentration and hydrolysis duration for the most preferred physical, chemical, and organoleptic characteristics of kweni mango syrup. The research was conducted from October 2024 to August 2025 at the Integrated Laboratory and Basic Science Laboratory of the Agricultural Institute (INTAN) Yogyakarta using a Completely Randomized Design (CRD) with a factorial pattern consisting of two factors and two replications. The first factor was the pectinase enzyme concentration (0%, 0.25%, 0.50%, and 0.75%), and the second factor was the hydrolysis duration (0, 30, and 60 minutes). Observation parameters included yield, vitamin C, viscosity, pH, total soluble solids, and organoleptic attributes. Data were analyzed using ANOVA at a 5% significance level followed by Duncan’s Multiple Range Test (DMRT). The results showed significant effects of both pectinase enzyme concentration and hydrolysis duration on yield, viscosity, total soluble solids, and organoleptic characteristics (color, taste, aroma, and overall acceptability), while no significant effects were observed on vitamin C content and pH. The best formulation was obtained using 0.50% pectinase enzyme concentration with a hydrolysis duration of 30 minutes.

This research originated from a concern about the existence of villages that are factually underdeveloped, but aren't recognized as 3T (Terdepan, Tertinggal, dan Terdepan) regions in the national regulatory framework. This research was conducted in Kabupaten Banyumas, which consists of 301 villages, with several villages indicated to be underdeveloped. Through the analysis of secondary data from BPS, Dinsospermades, and Bappedalitbang Banyumas, this study took 6 sample villages to analyze in order to understand the pattern of underdevelopment that is not covered by the formal 3T status. The purpose of this study is to highlight the reality of de facto remote areas that aren’t administratively recognized as 3T areas, and therefore don't have access to special funding schemes, and to examine the potential for replication of 3T area policies that can be adapted in Kabupaten Banyumas, with adjustments to local characteristics. Using a qualitative approach based on in-depth interviews with village government officials, this research mapped the needs, barriers, and opportunities for more contextualized policy interventions. This research recommends the development of a planning and budgeting model based on local needs and a social justice approach in the distribution of development resources. Thus, Banyumas can become an alternative policy laboratory to address development inequality outside the formal framework of the 3T regions.  

The livestock sector in Gowa Regency, South Sulawesi, has great potential but is often threatened by outbreaks of Foot and Mouth Disease (FMD), which cause significant economic losses. This study aims to evaluate the FMD control policies implemented by the Gowa Regency Government based on William Dunn's six policy evaluation criteria: effectiveness, efficiency, adequacy, equity, responsiveness, and accuracy. The study used a qualitative approach with primary data collected through in-depth interviews with key informants from the Livestock and Animal Health Division of the Gowa Regency Livestock and Plantation Service and supporting data from various literature. The findings show that the FMD control policy is effective in achieving zero cases, but efficiency is hampered by limited medical personnel (only two veterinarians) and operational budget dependence entirely on the Central Government. Vaccine adequacy is a pull sistem (demand-driven) and compensation distribution is carried out fairly. Community responsiveness increased after severe losses, and policy accuracy was considered most optimal in the implementation of biosecurity and sanitation while promoting vaccination. As a recommendation, the Gowa Government needs to recruit contract workers in the field of animal health, allocate funds for the procurement of operational vehicles and equipment to support laboratory facilities, and issue a Regent Regulation that strictly regulates the implementation of biosecurity and livestock housing patterns in high-risk areas.