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Vibrio sp. is one of the main pathogenic bacteria causing various diseases in whiteleg shrimp (Litopenaeus vannamei) cultivation, such as vibriosis, which can reduce the survival rate and productivity of ponds. Environmentally friendly Vibrio control efforts can be achieved through the use of probiotics. One widely used probiotic is Lactobacillus sp., which is known to suppress the growth of pathogenic bacteria through competition for space and nutrients, production of antimicrobial compounds (bacteriocins and organic acids), and increased shrimp non-specific immunity. This study aimed to determine the effectiveness of administering different doses of Lactobacillus sp. in suppressing Vibrio sp. populations in whiteleg shrimp cultivation media. The method used was a Completely Randomized Design (CRD) with four treatments and five replications: control (A), 6 ppm lactobacillus sp (B), 12 ppm (C), and 18 ppm (D). The parameter observed was the Total Vibrio Count (TVC) in the culture water after 24 hours of lactobacillus administration.

The normal flora of chickens refers to the microbial communities that naturally inhabit the gastrointestinal tract and body surfaces of chickens, playing a crucial role in health, digestion, and immunity. This community consists of beneficial bacteria such as Lactobacillus, Bifidobacterium, and Bacillus, which assist in feed fermentation, vitamin synthesis, and inhibition of pathogenic growth. Additionally, the normal flora may include potential pathogenic bacteria such as Escherichia coli, Salmonella spp., and Campylobacter, which can cause diseases if microbial balance is disrupted. The diversity and balance of the microbiota are influenced by various abiotic factors, including feed quality, access to clean water, ambient temperature, humidity, and environmental hygiene. Biotic factors, such as microbial interactions, rearing systems, and contact with other animals, also play a significant role in determining microbial composition. Several studies have shown that the use of feed additives, such as probiotics and phytogenics, can enhance populations of beneficial bacteria while suppressing pathogenic bacteria. Extensive rearing systems, which provide chickens with more space and exposure to natural environments, tend to increase microbiota diversity compared to semi-intensive systems with more restricted conditions. Understanding these factors is essential for developing effective health management strategies and optimizing safe and sustainable poultry production.

COVID-19 is caused by the SARS-CoV-2 virus which infects the respiratory system and transmitted by droplets. This study aims to see the effect of administering Nigella sativa which has an immunomodulatory effect in reducing the clinical manifestations of COVID-19 disease by increasing the immune system. The method used is a literature review of five selected journals through a prism diagram flow from the PubMed, SpringerLink, and ScienceDirect electronic databases. Clinical manifestations of COVID-19 in patients decreased the length of patients’ hospital stay which become shorter in the intervention group compared to the control group. Nigella sativa has a positive response to increasing immunity. The immunomodulatory effect of NS is proven in increasing macrophage phagocytosis, immunoglobulin titer, lymphocyte ratio, and preventing T cell depletion and encouraging specific T cell proliferation.

This community service program aims to develop nutraceutical-based health products from temu mangga (Curcuma mangga Val.van Zip) and probiotics, called "TEMAPRO". Research and socialization were conducted in Pulau Semambu Village, South Sumatra, targeting village mothers who have limited knowledge about the benefits of herbs and probiotics. Temu mangga, which is traditionally consumed as a salad and herbal medicine, contains various active compounds that have the potential as antioxidants and anti-cancer. Combined with the probiotic Lactobacillus rhamnosus, this product is expected to support digestive health and increase body immunity. Implementation methods include education, training in making temu mangga extract, mixing with probiotics, and product packaging techniques. The results of the activities showed an increase in community understanding and skills in processing local materials into health products with economic value. It is hoped that "TEMAPRO" will not only improve the quality of public health, but also open up business opportunities in the village through local nutraceutical products.

Sleep is a vital process for human recovery, occurring predominantly during rest. High-quality sleep is essential for the recovery process, helping to alleviate excessive fatigue, while poor sleep quality can lead to reduced immunity. One significant issue affecting young people today is sleep quality, which is influenced by various factors, including smartphone use. This study aimed to investigate the relationship between smartphone addiction and sleep quality among the youth of the GMIM "Eben Haezar" Kaaten. Conducted in August 2024, this cross-sectional study included all 173 youth registered in the GMIM Youth SIT, with a research sample consisting of 63 respondents. The study variables were smartphone addiction and sleep quality, analyzed using univariate and bivariate methods. Results showed that 36 respondents (57.1%) experienced a high level of smartphone addiction, while 28 respondents (44.4%) reported poor sleep quality. The study concluded a significant relationship between smartphone addiction and sleep quality, with a p-value of 0.010 and a significance level of α = 0.05.

The immunity of Ploso Village residents is experiencing a decline, marked by increasing complaints of fever, dizziness and flu as a result of the current transition. Based on this, this service is carried out to utilize TOGA which has been planted by residents in their yards into a drink that can increase the body's immunity because it contains antioxidant compounds. This activity was carried out in Ploso Village in February-March 2024. Using socialization, discussion, practice and evaluation methods. Participants who took part in this training were women from PKK Prima Sejahtera. The results of this activity are 1) Participants understand that the bioactive compounds found in several plants can be used as drinks/wedang to increase the body's immunity. 2) Participants can make spiced wedang from TOGA grown in their yard. 3) Participants are very enthusiastic about this service activity.

Background: Complete Basic Immunization (IDL) is an indicator in the immunization program. IDL aims to actively gain early immunity. IDL data at Puskesmas X in 2021 was 83.5% and there was a decrease in the percentage rate in 2022 to 82.87%. Based on an initial survey, on May 9-19, 2023, it was found that out of 73 mothers who brought their children to the posyandu for immunization, around 22 children (30%) were not fully immunized. Objective: Knowing the factors that influence the completeness of immunization in the working area of Puskesmas X Pekanbaru City. Methods: Using analytic observational study design, with cross sectional research design. This research was conducted at Puskesmas X Pekanbaru city. The sampling technique was done by accidental sampling. Variables of knowledge level, and education were analyzed using Kendall Tau test, while variables of employment, family support, mother's attitude and number of children used contingency coefficient test. Results:  The results of the Kendall Tau test analysis of the variable level of knowledge, and education obtained a p value of 0.001 and 0.392 respectively. While in the contingency coefficient test the variables of employment, family support, maternal attitudes and number of children obtained a p value of 0.889; 0.000; 0.000 and 0.455 respectively. Conclusion: There is a significant relationship between the level of knowledge, mother's attitude and family support with the completeness of basic immunization of infants aged 12-24 months in the working area of Puskesmas X Pekanbaru City.

The growth and development in toddlers is influenced by the cheir nutritional status, which is related to feeding practices. Improper nutrition can hinder  growth and development leading to  decreased immunity. Tui Na massage is a non-pharmacological therapy that can address eating difficulties and  increase appetite thereby aiding weight gain in toddlers. The objective of this study  is to understand and apply nursing care to malnourished toddlers using  Tui Na Massage innovation as a safe and effective non-pharmacological therapy to increasing  weight. Nursing care for malnourished toddlers from families  Tn. A and Tn.S included assessment, data analysis, nursing diagnosis, nursing plan, nursing implementation and evaluation from  April 22-28 2024. Tui Na massage for six consecutive days was proved to increase appetite and added  0 .5 kg toddlers weight. Tui Na massage can be recommended as a safe, effective, cost-effective non pharmacological therapy that parents can regularly,and correctly administer to help increase the child's weight.

Immunization is one of the main goals of vaccination, which is basically can have passive or active immunity. Immunization is carried out in order to prevent the occurrence of diseases that can be prevented by carrying out immunization. The government is obliged to provide complete immunization for every baby and child. This study aims to analyze family knowledge and support for the completeness of basic immunization in the working area of the Parsoburan Health Center. This type of research is a quantitative study using a cross sectional approach. The number of samples in this study were 40 research samples. After conducting the research, it can be concluded that there is a relationship between knowledge and the infant's immunization status, a p-value of 0.000 is obtained, which is less than 0.05. There is a relationship between family support and infant immunization status with a p-value = 0.000 where the value is less than 0.05. It is hoped that the puskesmas will always provide information related to basic immunization for infants.

Early breastfeeding (ASI) in the first days of birth provides many benefits where there is colostrum which is proven to be very rich in antibodies which can increase the baby's immunity. Prelacteal food is given to babies in the first days after birth on the grounds that breast milk (ASI) has not been released so that the first days after birth are a vulnerable period for babies to receive prelacteal food/drinks. Prelacteal foods are dangerous because they can replace colostrum as the baby's earliest food. The impact of prelacteal feeding is that babies may get diarrhea, septicemia (bacterial infection in the blood), and meningitis, babies are more likely to suffer from intolerance to the protein in the formula, and develop allergies such as eczema. Method: this activity begins with the preparation of proposals and administration activities in May 2023. The implementation of this activity is educating mothers about prelacteal feeding to babies aged 0-6 months. Results: 30 participants in this activity were mothers who had babies aged 0-6 months in the village of Bangun Rejo. In its implementation, it was explained about the types of prelacteal feeding, the impact of prelacteal feeding, factors that can influence mothers to give prelacteal feeding. Conclusion: community service activities based on health education are carried out. This community service activity was carried out for 3 months starting in May-July 2023. The results of this community service regarding prelacteal feeding in infants aged 0-6 months.

Virus Corona atau severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adalah virus yang menyerang sistem pernapasan. Terdapat 240 zona merah covid-19 di seluruh Indonesia, dan terdapat 5 zona merah untuk Provinsi Sulawesi tenggara yaitu kota Kendari, kota Bau-bau, Kolaka, Muna dan Konawe. Berbagai regulasi diterbitkan oleh pemerintah dalam upaya penanggulangan covid-19 termasuk didalamnya adalah program vaksinasi yang diharapkan dapat membentuk kekebalan kelompok/ herd immunity. Salah satu indikator keberhasilan program vaksinasi adalah terbentuknya antibodi anti SARS-CoV-2 (IgM dan IgG). Tujuan kegiatan adalah melakukan kegiatan skrining berupa pemeriksaan antibodi SARS-CoV-2 sebagai salah satu indikator keberhasilan program vaksinasi covid-19 bagi siswa-siswi SMAN 1 Soropia. Metode yang digunakan dalam kegiatan ini adalah metode imukokromatografi. Hasil skrining antibodi SARS-CoV-2 memperlihatkan hasil positif/reaktif sebanyak 32 orang (43%) yang tersebar menjadi reaktif IgM sebanyak 12 orang  (16%), IgG sebanyak15 orang (20%), IgM dan IgG sebanyak 5 orang (7%), serta hasil negatif/ non reaktif sebanyak 43 orang (57%). Seyogianya, program vaksinasi dikatakan berhasil jika dapat merangsang pembentukan antibodi dalam  tubuh, namun dalam kenyataannya lebih dari 50% subjek yang menunjukkan hasil negatif/ non reaktif. Hal ini dapat disebabkan oleh banyak faktor seperti efikasi vaksin dan juga respon imun tiap orang.

Background : Early Initiation of Breastfeeding (IMD) is the process of placing a newborn on the mother's chest or stomach so that the baby can naturally find its own source of breast milk or breast milk and start breastfeeding. The baby will get immunity. IMD is beneficial for mothers because it can help speed up the postpartum recovery process Research purposes : To find out the relationship between parity, type of delivery and the age of the mother to the provision of early breastfeeding initiation (IMD) at the Lemahduhur Health Center in 2022 Research methods : The type of research used in this research is quantitative with a cross sectional research design. The population in this study is168 mothers giving birth. The sample in this study were 63 mothers giving birth using the accidental sampling technique. Bivariate analysis using the chi-square test. Research result : The distribution of the frequency of parity descriptions of mothers giving birth at the Lemahduhur Health Center in 2022 is partly 1-4 times as many as 45 people (71.4%). The distribution of the frequency of descriptions of the types of maternal deliveries at the Lemahduhur Health Center in 2022 is mostly normal, with 41 people (65.1%). The frequency distribution of the description of the age of mothers giving birth at the Lemahduhur Health Center in 2022 is mostly 20-40 years, with 36 people (57.1%). The distribution of the frequency of giving Early Breastfeeding Initiation (IMD) at the Lemahduhur Health Center in 2022 is mostly yes, as many as 42 people (66.7%). Conclusion : Can be concluded thatthere isthe relationship between parity, type of delivery and the age of the mother to the provision of early breastfeeding initiation (IMD) at the Lemahduhur Health Center in 2022.

In general, Tinawun Village has a lot of potential to become a prosperous and prosperous village. In addition to having fertile soil, good human resources, healthy and conducive village government, Tinawun Village has one potential village tourism, namely Religious tourism to the Tomb of Sheikh Zakaria every Kliwon Friday. However, apart from tourism, there are many things that can be used in Tinawun Village, namely corn, which is usually only used for cooking, but now it can be used as a source of income for residents by making rice. In addition to corn, there is also ginger which is usually only used as an additional spice in the kitchen, now it can be processed into a drink that is rich in benefits and helps increase body immunity, by mixing it with various flavors, it can be turned into an immune boosting drink that can increase the body's immunity during this pandemic. Apart from the plant aspect, there is also the empowerment of catfish as an income source for local residents.