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Breast cancer patients who are undergoing chemotherapy need positive support to further motivate them in dealing with the treatment. Patients undergoing long-term chemotherapy treatment tend to be more susceptible to compliance problems because they often feel bored to continue undergoing treatment and ultimately do not comply with the treatment. The type of research uses a quantitative analytical research design with a cross-sectional approach. Population and sample, the population in the study of patients undergoing chemotherapy in the Delima room and Irina A room with a Purposive sampling technique with the Slovin formula.The results of respondents based on low psychosocial needs (24.1%) and high Psychosocial Needs (75.9%) and the odd Ratio value = 17.1 was obtained. Which shows that if psychosocial needs are high, patients get motivation in undergoing chemotherapy. While in low Spiritual Needs (25.9%) and high spiritual needs (74.1%) which shows that if spiritual needs are high, patients get motivation in undergoing chemotherapy. Based on the Chi-Square test, it can be concluded that p = .001 < a = 0.05. The conclusion in this study is the relationship between Analysis of psychosocial and spiritual needs and patient motivation in undergoing chemotherapy at Prof.DR.RD. Kandou Manado General Hospital.

Propionibacterium acnes is an anaerobic bacteria that plays an important role in dermatological research, especially in the context of skin diseases such as acne vulgaris. This study aims to optimize the growth conditions of Propionibacterium acnes in sodium media in order to increase the effectiveness of bacterial culture on a laboratory scale. The parameters tested include media pH, sodium concentration, incubation temperature, and incubation time. The research method was carried out systematically and controlled with a completely randomized design using several environmental condition treatments. The results showed that optimal growth of Propionibacterium acnes was achieved in media with a pH of 6.5–7.0, a sodium concentration of 1.5%, an incubation temperature of 37°C, and an incubation time of 72 hours in conditions without oxygen (anaerobic). By knowing the right conditions, Propionibacterium acnes bacteria can grow faster and optimally, so that it can help in dermatological research or product development related to skin health.

Pain and inflammation are two clinical conditions that often occur together, especially in musculoskeletal disorders. Non-steroidal anti-inflammatory drugs (NSAIDs) are often used because they have dual effects as analgesics and anti-inflammatories. This study aims to compare the effectiveness of several types of NSAIDs in reducing pain intensity and inflammatory responses. This study used an experimental design with test animal subjects divided into several groups, each receiving treatment with different NSAIDs, namely ibuprofen, diclofenac sodium, and mefenamic acid. Pain assessment was carried out using the visual analog scale (VAS) method, while inflammation was measured by observing edema and inflammatory biomarker levels. The results showed that all three types of NSAIDs had a significant effect on reducing pain and inflammation compared to negative controls, but there were differences in effectiveness between drugs. Ibuprofen showed higher potential in relieving pain, while diclofenac was more effective in suppressing the inflammatory process.

Dry noodles are one type of noodles in Indonesia. Noodles are a type of food that is low in protein and other nutrients, but high in carbohydrates. This is because the main ingredient in making noodles uses various types of flour, one of which is wheat flour. The purpose of this study was to ascertain the effect of adding genjer and spinach on the chemical and sensory qualities of dried noodles and to identify the optimal treatment combination in terms of nutritional value, antioxidant activity, and color that consumers like. The method used in this study was a completely randomized factorial design (CRD) in a two-factor variation with two repetitions, namely genjer puree concentrations of 10, 20 & 30% and spinach puree concentrations of 10, 20 & 30%. The results of the study found that the higher the concentration of genjer pulp, the higher the ash, protein, fiber, and total phenol content but not for the antioxidant activity. The addition of spinach puree apart from being a natural colorant can also help increase the fiber, ash, and antioxidant content of the noodles. Noodles had the best results of chemical analysis in the combination treatment of 20% genjer puree and 30% spinach puree with the results of 5.03% water content, 0.90% ash content, 12.12% protein, 9.93% fiber, 73.15% antioxidants, phenol 2.62 mgGAE/g. Dry noodles made from genjer and spinach have the potential to be developed because they have high antioxidant activity.

Kombucha is one of the processed products of fermented sugar and tea with a starter mixture ofkombucha culture called SCOBY (Symbiotic Cultures of Bacteria and Yeast). Kombuchafermentation is carried out using yeast and bacteria microorganisms. Pomegranate or often calledpomegranate is a fruit that has quite high antioxidants. The purpose of this study was to determinethe characteristics of pomegranate juice kombucha with variations in concentration andfermentation time which have high antioxidant activity. This study used a factorial randomizeddesign with two factors and two repetitions. The factors used were variations in the percentage ofpomegranate juice (30%, 40%, and 50%) and fermentation time (7 days, 9 days, and 11 days). Thebest chemical and organoleptic analysis based on the highest antioxidant activity was 50%pomegranate juice treatment and 9 days of fermentation time with 71,10% antioxidant activity,total phenol 9,04 GAE/L, reducing sugar 2,45%, total acid 1,35%, pH 3,1 , anthocyanin 53.52%,lightness (L*) 44.72 , redness (a*) 5.15, yellowness (b*) 2.57, fruity aroma 2.27, sour taste 2,85, andfor overall preference 3,49 for the treatment of adding 50% pomegranate juice and 9 days offermentation time. Pomegranate extract able to improve activity of antioxidant for kombucha. 

Indonesia is rich in biodiversity, there are around 40,000 species of plants, and they have different uses,such as traditional medicine, can be made into handicrafts, used as decorations, used as natural dyes. Butterflypea flowers have the potential as a natural dye because the anthocyanins contained in their petals emit a bluecolor. The purpose of this study was to determine the anthocyanin content in butterfly pea flowers using themaceration extraction method which is commonly used to determine the best anthocyanin concentration. Thisstudy used a completely randomized factorial design (CRD), namely drying time, (fresh, 1, 2 days) andmaceration temperature (50, 60, 70oC), so that 9 combinations were obtained and each treatment was repeatedtwice. The results of this study indicate that the longer the drying time and the higher the macerationtemperature, the higher the levels of anthocyanin, total phenol, and the darker the color. The researchconducted showed that the best treatment combination was the drying time of 2 days with a macerationtemperature of 70°C to produce butterfly pea flower extract which had antioxidant activity of 54.66%, totalphenol 4.16 KTF (mgGAE/g), anthocyanin 123.48 mg/g, pH 6.03. Color sensory test analysis was 4.5 andwater content of butterfly pea flower was 10.79%. The optimal drying time and maceration temperature willproduce high total phenol and anthocyanin levels. Butterfly pea flowers have high levels of anthocyanins, sothey have the potential to be studied further. 

This applied scientific work is entitled "Design of Automatic Smart Berthing System Based on Arduino". Ships are a comfortable alternative transportation. Currently, ship development is needed so that they can operate properly. During the docking process, ship accidents often occur in ports both nationally and internationally. Therefore, a better development or safety is needed that can be given to ships during the docking process. This tool uses the Arduino Nano microcontroller as the main control and an ultrasonic sensor as a distance counter to prevent accidents. This applied scientific work aims to realize and facilitate work on the ship by abandoning manual methods. Berthing is the location of the ship's mooring or security, the area around the ship where the anchor is thrown, the ship's residence, employing the ship's crew and positioning the ship in the desired place. This scientific paper uses experimental research as its research method. The use of experimental research methods in educational research will be faced with problems concerning research subjects. Experimental research is also research that is carried out intentionally by researchers by providing certain treatments to research subjects in order to create a tool or design that is expected by the researcher.

Hypovolemic shock is a condition of reduced organ perfusion and oxygenation to tissues caused by acute loss of blood (hemorrhagic shock) or body fluids (non-hemorrhagic) which can be caused by various circumstances resulting in multiorgan failure. The mortality rate in injured patients who experience hypovolemic shock in clinics with a total care level reaches 6%. Relevant articles were searched through an electronic database, Google Scholar, using the keywords “Fluid Resuscitation in Patients with Hypovolemic Shock”. The treatment to prevent hypovolemic shock is fluid resuscitation. The classic symptoms of shock are, blood pressure decreases dramatically and is not stable even though the position is lying down, the patient suffers from severe tachycardia, oliguria, agitation or confusion, increased sympathetic work, hyperventilation, collapsed veins, release of stress hormones and large expansion to fill the volume of blood vessels using interstitial fluid, intercellular fluid and reduce urine production. Management of hypovolemic shock due to fixed bleeding begins with an assessment of airway, breathing, circulation, diability and exposure. Then after initial management, the response is evaluated, which can be rapid, temporary, and minimal or no response.

Natural fibers can be used as an alternative basic material for produce SNI helmet that are environmentally friendly. A huge potential of hemp fiber in Indonesia has not apply properly yet. This study propose to determine the ability of tensile strength and impact toughness in hemp fiber composites so that hemp fiber can be used as an alternative material for making SNI helmets. This study uses an unsaturated polyester 157 BQTN-EX resin matrix and MEKPO catalyst. Alkali treatment of the fibers uses 5% NaOH for 2 hours. The composite is made using the hand lay-up method. Variations volume fraction of hemp fiber used are 30%, 40%, 50%. The tensile testing process uses the ASTM D 638-03 standard and impact toughness testing uses the ASTM D 265-03 standard. Based on the research results, the highest tensile test results were obtained at variation on 30% fiber volume fraction is 18.30 MPa, for the highest impact toughness test results were obtained at variation on 50% fiber volume fraction is 0.0248 J/mm2. The greater the variation of the fiber volume fraction given, the lower the tensile strength value produced, while the higher the variation of the fiber volume fraction given, the greater the energy absorbed so that the impact price increases. Based on the test results, this hemp fiber composite needs to be considered as an alternative material to replace SNI helmet manufacturing.

Uncollectible receivables have a considerable risk and can reduce the level of company profitability. Therefore, every company needs to pay special attention to the management of receivables so as not to cause losses. One of the appropriate methods for recording bad debts in the financial statements is the reserve method. Therefore, the company forms a reserve based on estimates of receivables that are estimated to be uncollectible. The purpose of this study is to evaluate the way accounting treats receivables and how this impacts the financial statements. Using primary data, this research was conducted at KOPERINDO JATIM Kandat, which is located at Jl. Raya Kediri, Kandat Village, Kandat District, Kediri Regency, East Java 64173. Quantitative descriptive analysis was used to analyze the data. The results of the analysis show that, using the percentage of sales approach, the total amount of bad debts will reach Rp23,272,860 in 2024. In contrast, using the reserve method with the percentage of receivables approach, the amount of bad debts will reach Rp120,669,520 in 2024. Based on these results, the calculation of the reserve method with the percentage of receivables approach is in accordance with the theory, which aims to add the amount of accounts receivable to the total receivable.

The principles of democracy in the Hadith perspective reflect Islamic beliefs that emphasize the values of equality, deliberation, and justice. Although the word “democracy” is not found in the hadith texts, the teachings on the basic principles of democracy contain and underlie people's participation, freedom of speech, and respect for the rights of each individual that can be found in the teachings of the prophet Muhammad SAW. Hadiths related to deliberation (shura), social justice, and leader selection indicate that decision-making in society should be based on inclusiveness, transparency, and responsibility. For example, hadith-reports that suggest deliberation in dealing with important issues indicate respect for individual voices and opinions in a collective decision. In addition, the concept of justice in the hadith emphasizes the importance of equal treatment of all members of society without discrimination. The purpose of this article is to provide knowledge about democracy in the Hadith perspective in the perspective of hadith. Thus, the hadith perspective provides a moral and ethical foundation for the implementation of democratic principles that are oriented towards the welfare of the people and the fair management of public interests. 

Human Immunodeficiency Virus (HIV) is a retrovirus that targets the human immune system, particularly cells with CD4 receptors such as T lymphocytes, monocytes, and macrophages. This virus causes progressive damage to the immune system and, if left untreated, can develop into Acquired Immunodeficiency Syndrome (AIDS). HIV is transmitted through sexual contact, blood transfusions, shared needles, and from mother to child during pregnancy, childbirth, or breastfeeding. HIV has become a global pandemic, with over 39 million people living with the virus in 2022. In Indonesia, the HIV epidemic is diverse, with high-risk groups including injection drug users, men who have sex with men, sex workers, and transgender individuals. The pathogenesis of HIV involves infection of immune cells, integration of viral DNA into the host genome, and production of new virions, leading to a gradual decline in immune function. HIV diagnosis is conducted through serological and virological testing, while antiretroviral therapy (ART) is the standard treatment to suppress viral replication, preserve immune function, and improve patients' quality of life and life expectancy. Early detection and proper management of HIV are crucial to preventing progression to AIDS and reducing transmission within the population.

Ovarian cysts are ovarian tumors that can be either neoplastic or non-neoplastic, with varying characteristics in terms of size, consistency, and malignancy. During pregnancy, the most commonly encountered types include dermoid cysts, endometriomas, and lutein cysts. The actual prevalence of ovarian cysts is difficult to determine as most cases remain undiagnosed, with studies indicating that around 4% of women will experience hospitalization due to ovarian cysts by the age of 65. Evaluation of ovarian masses requires a multidisciplinary approach, including ultrasonography and tumor markers to assess the likelihood of malignancy. This case involves a 45-year-old woman who presented with lower abdominal pain, bloating, and significant weight loss. Ultrasound findings revealed a cystic mass with solid components, suspected to be a malignant ovarian cyst. The provisional diagnosis was cystic ovarian neoplasm with suspected malignancy, and the patient underwent laparotomy with right salphingo-oophorectomy. Post-surgery, the patient's condition improved, though she continued to experience pain at the surgical site. Ovarian cysts can present with nonspecific symptoms and are often found incidentally. Further evaluation is necessary to assess malignancy and determine appropriate treatment. Surgical intervention is required for cases with suspected malignancy, especially in cysts with solid masses and large size.

The Snail Canning Industry has the potential to impact the environment if wastewater with high organic compound content is not treated first. This study aims to analyze the performance of the Snail Canning Industry Wastewater Treatment Plant (WWTP) based on BOD, COD, and TSS parameters. The method used is descriptive, with primary data obtained through interviews and secondary data from laboratory test results. Measurements were taken at the inlet and outlet points of the WWTP, then compared with the quality standards based on the Regulation of the Minister of Environment No. 5 of 2014. The results showed that the WWTP succeeded in reducing the concentration of BOD from 201 mg/L to 6 mg/L, COD from 315 mg/L to 24 mg/L, and TSS from 25 mg/L to 6 mg/L. The reduction efficiency of each parameter was 97.01% for BOD, 92.38% for COD, and 76% for TSS. All outlet results met the established quality standards. This indicates that the wastewater treatment process at the IPAL functions effectively in reducing the levels of pollutant parameters in wastewater.

The development of fettuccine pasta products with the addition of tilapia and binahong leaves aims to find the composition of the ingredients of fettuccine pasta that is preferred and well accepted by the panelists. The methods used are experimental method and hedonic test. The experiment of making fettuccine pasta with the addition of tilapia and binahong leaves used a formulation with 3 treatments, namely F1 for the addition of 15 g of tilapia and 35 g of binahong leaves, F2 for the addition of 10 g of tilapia and 40 g of binahong leaves, and F3 for the addition of 5 g of tilapia and 45 g of binahong leaves. The hedonic test involved 25 semi-trained panelists. The results showed that fettuccine pasta with the addition of 15 g of tilapia and 35 g of binahong leaves was the most preferred product and was well accepted by the semi-trained panelists. The composition of the ingredients of the substituted fettuccine pasta with tilapia and binahong leaves that had the best acceptance included 200 g of semolina flour, 15 g of tilapia, 35 g of binahong leaves, 180 g of chicken eggs, 1 tsp of salt, and 1 tsp of olive oil.

Kabaddi is a traditional outdoor game played with slight variations across India. Prevention of hamstring injuries in kabaddi athletes requires a multifaceted approach, including a balanced muscle strengthening program, regular flexibility training, thorough warm-up before the match, and adequate recovery after intense activity. This study aims to analyze the effect of sports massage on muscle flexibility and pain threshold in the hamstring muscles of Surabaya Kabaddi athletes. The research method used was quantitative with a pretest-posttest design in two groups, namely the experimental group given sports massage intervention and the control group. The sample in this study was 12 Surabaya Kabaddi athletes who were divided into 2 groups, namely the treatment group and the control group using the Total Sampling technique. The results of the Paired t-test showed that there was a significant effect on the hamstring muscles after being given sports massage and a decrease in the pain threshold in the experimental group compared to the control group, as evidenced by the results of the t-test which showed a significant value <0.05. It can be concluded that sports massage can have an effect on hamstring muscle flexibility and pain threshold.

Approximately 35.4% of the Asian population suffers from Tinea corporis, a superficial dermatophyte fungal infection that attacks hairless skin such as the face, arms, and legs. This dermatophyte causes symptoms in the form of circular lesions with active red and scaly edges and a calmer center. This case involved a 12-year-old girl who came to the Dermatology and Venereology Polyclinic of Fauziah Bireun Hospital with complaints of reddish spots on her body that had lasted for eight months. The lesions were accompanied by itching, especially when sweating or in hot conditions, but improved after bathing. The clinical diagnosis showed Tinea corporis. The therapy given was 2% ketoconazole cream applied twice a day and systemic treatment with 200 mg itraconazole and 10 mg cetirizine. This management aims to overcome fungal infections, reduce symptoms, and prevent recurrence. Patient education regarding personal hygiene and prevention of skin moisture is an important part of therapy.

Fertilization is one of the important activities in plant cultivation because it plays a role in increasing productivity by maintaining soil fertility. This experiment aimed to test the effectiveness of NPK fertilizer (20-51-13) on the growth and production of cabbage plants and its agronomic effectiveness. The experimental design used was a randomized block design. The treatments tested: without application of the tested fertilizer (P0), application of inorganic fertilizer comparison (2 kg/ha/application) (P1), and 5 levels of NPK fertilizer (20-51-13) tested, namely: 1.0, 1.5, 2.0, 2.5, and 3.0 kg/ha/application. The recommended doses of urea, SP-36, and KCl fertilizers were  200, 100, and 100 kg/ha, respectively. The results showed that the application of NPK fertilizer (20-51-13) can increase the growth of cabbage plants as indicated by the variables of plant height and number of cabbage leaves compared to the control treatment. In addition, the application of NPK fertilizer (20-51-13) increased the yield components of cabbage plants compared to the control treatment. The treatment of 0.75 doses of NPK fertilizer (20-51-13) was agronomically effective because it produced the highest relative agronomic effectiveness value of 145%, which means it can increase yields by 1.45 times. The recommended dose for cabbage plants is 1.5 kg/ha/application of NPK fertilizer (20-51-13) applied 5 times at 2, 3, 4, 5, and 6 WAP.

Kwashiorkor is a form of protein energy malnutrition (MEP). Malnourished toddlers have short and long term effects, in the form of impaired growth and development, including impaired cognitive function, morbidity, risk of degenerative diseases in later life and death. The male patient aged 1 year and 2 months was brought by his parents to the emergency room of Cut Meutia Hospital on Tuesday, June 4, 2024 at 20:07 WIB with complaints of swelling on both backs of legs and hands and face. On the antopometric examination on the first day of treatment, the patient's nutritional status was found to be poor. Patients are given malnutrition management which is divided into 3 phases, namely stabilization, transition and rehabilitation.   Kata kunci: Antropometri, Kwashiorkor, Malnutrisi Energi Protein

This research aims to improve student learning outcomes through the inquiry method on the subject of special treatment of fruit plant seeds. The study was conducted as classroom action research (CAR) at SMKN 1 Gondang for class XI Agribusiness of Food Crops and Horticulture (ATPH). The research was carried out in two cycles, each consisting of planning, action, observation, and reflection. Data were collected through tests and observation sheets. The results show that the inquiry method significantly improves student engagement and cognitive outcomes. Average class performance increased from 62% in Cycle I to 85% in Cycle II. These findings suggest that inquiry-based learning can enhance students' critical thinking and understanding in agricultural subjects.