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Failure in Realizing the Development of the Integrity Zone Towards WBK/WBBM is due to the failure to develop a systematic and consistent change in mindset and work culture. This failure is due to the failure to form an effective work mechanism, the failure to form a mindset of employees in public services, and leaders who have not optimally provided influence as role models. Releasable theories as stipulated in Permenpan RB Number 90 of 2021. The research method uses qualitative descriptive research methods. The results of the study (1) The involvement of all employees is very important because it shows commitment and responsibility in developing the Integrity Zone (2) The aspect of Change Management is collective work and high commitment from employees. (3) Optimization of Change Management includes developing changes in mindset and work culture, in the agenda of change, leadership as a role model has high optimism. (4) Controlling resistance to change requires strategic efforts in handling it.

Background: Stunting in toddlers can have an impact on children's health and intelligence in the future, such as the body's resistance to infections or viruses and decreased academic performance. Objective: to train posyandu cadres in improving anthropometric measurement skills in toddlers. Method: The method used in this activity is providing materials, training and simulation of anthropometric measurements. The targets for this activity are posyandu cadres from RW 03, Pulo Gebang Village. This community service activity will be carried out in August 2024 at the RW 03 hall, Pulo Gebang Village. Results: the implementation of this community service resulted in an increase in posyandu cadres' understanding of stunting and anthropometric measurement methods with good understanding from 2% to 76%. Cadres with sufficient understanding are 24%. Conclusion: Improving the skills of posyandu and KIE cadres regarding stunting can improve stunting prevention efforts.

The development of information systems in educational management has become a very necessary need to improve the efficiency and effectiveness of educational institution management. This study explores the concept and implementation of information systems in educational management in Christian educational institutions. The main focus of this study is to understand how information systems can support administrative processes, academic systems, curriculum management, and interactions between educators and students. This study uses a qualitative approach with a literature study method in several Christian educational institutions. The results of the study indicate that the implementation of appropriate information systems can improve the quality of educational services, facilitate access to information, and improve overall organizational performance. However, challenges such as limited resources and resistance to change need to be overcome to achieve successful implementation. This study provides practical recommendations for Christian educational institutions to optimize the use of information systems in their educational management.

This study aims to evaluate the accuracy of the Fibonacci Retracement and Moving Average Convergence Divergence (MACD) technical indicators in analyzing the movement of banking stock prices listed on the LQ45 index in the 2020 period. Based on data from PT Kustodian Sentral Efek Indonesia (KSEI) in 2023, there was a significant increase in the number of investors in the Indonesian stock market by 103.6 percent in 2020. This study uses a quantitative descriptive approach with a census method for sampling, which resulted in 5 banking companies as samples: BBCA, BBNI, BBRI, BBTN, and BMRI. Data analysis was carried out using the Fibonacci Retracement indicator to identify potential support and resistance levels, and the MACD indicator to evaluate the strength, direction, and momentum of stock price movements. The results showed that 11 of the 11 signals generated by the Fibonacci Retracement were proven to be accurate, while 43 of the 53 signals generated by the MACD were also proven to be accurate. In conclusion, the buy and sell signals generated by the Fibonacci Retracement and MACD indicators are reliable and effective for use in banking stock trading.

This study presents a case study on the implementation of community-based development programs in disadvantaged areas, focusing on the challenges and successes encountered during the execution of these initiatives. Utilizing a qualitative approach, the research involved in-depth interviews with various stakeholders, including community members, local government officials, and representatives from non-governmental organizations. The findings indicate that community engagement in the development process not only enhances the effectiveness of the programs but also strengthens the sense of ownership and responsibility among residents. However, the study also identifies several challenges, such as limited resources, inadequate infrastructure, and resistance to change, which can hinder progress. These findings underscore the importance of a collaborative approach and sustained support from all stakeholders to achieve success in community-based development. Furthermore, the research highlights the necessity of tailoring programs to meet the specific needs and contexts of the communities involved. This study provides valuable insights for policymakers and practitioners in designing and implementing more effective development programs in disadvantaged areas, emphasizing the critical role of community participation in fostering sustainable development.

Organizational culture change in the healthcare sector has a significant impact on the quality of services provided. In a dynamic environment, healthcare organizations must be able to adapt their internal culture to face new challenges, such as technological developments, regulatory changes, and increasing expectations from patients and the public. This study aims to explore the effect of organizational culture change on the quality of healthcare services through a systematic literature review. The methodology used is the Systematic Literature Review (SLR) with data analysis from various relevant studies. The results show that cultural change that supports employee engagement and focuses on patient satisfaction can improve operational efficiency and service quality. However, challenges such as resistance to change and limited resources remain obstacles that must be overcome. The conclusion of this study emphasizes that organizational culture change is not only a strategic step to improve service quality, but also a long-term investment that can improve employee engagement and patient satisfaction.

The process of aging in the course of human life is a natural thing. A common problem experienced by elderly people related to physical health is that they are susceptible to various diseases, due to reduced body resistance in dealing with external influences. Low back pain or lower back pain is a feeling of discomfort that can cause various kinds of disorders that can cause health problems in human life. So it is important for people to understand about low back pain. Therefore, there is a need to increase knowledge and understanding at community health centers about low back pain, including signs of symptoms, prevention and treatment for the elderly at Posyandu, Kedungkandang Village. The method used is to provide physiotherapy education in the form of health promotion about low back pain to elderly posyandu participants using posters as an educational medium. Questions and answers to participants to measure effectiveness and provide independent training education. The activity ran smoothly and was easily understood by the elderly at the Posyandu, Kedungkandang Village and could increase participants' knowledge about cases of low back pain.

Optimizing education management in schools is a strategic step to achieve superior education quality, where various aspects such as human resource development, utilization of facilities and infrastructure, and education supervision play an important role in creating a conducive learning environment and responsive to student needs. The purpose of this study is to examine more deeply the role of education management in realizing quality schools. The research method to be used in this study is a literature study approach, in which data and information will be collected from various academic sources, such as books, journals and relevant articles on education management and quality schools. The results of this study show that effective education management plays a key role in creating quality schools through key components such as human resources, facilities and infrastructure, finance and education supervision. Each of these components works synergistically to support optimal learning processes, although they often face challenges such as limited resources, resistance to change and lack of stakeholder support. Through collaborative strategies from various parties, including the government, community and parents, schools can overcome these obstacles. Optimizing education management complemented by educational supervision helps improve the professional quality of teachers, curriculum and school management, and builds a culture of continuous evaluation. This synergy results in schools that are qualified, adaptive and able to respond to the demands of today's education.

This study examines women's political communication in Maluku, focusing on the opportunities, challenges, and socio-cultural dynamics they face. In a region strongly influenced by patriarchal culture, women's roles in politics are often constrained by traditional social views and resistance to their involvement in a male-dominated political arena. The complexity of this issue is heightened by the perception that politics is a harsh and competitive domain. The aim of this research is to understand the communication strategies used by female politicians in Maluku and to identify the factors that influence their success or failure in the political field. This study employs a qualitative method, gathering data through in-depth interviews with female politicians, activists, and political observers in Maluku. The findings reveal that despite significant challenges, female politicians are able to leverage local values such as community solidarity and the adat-based social system to strengthen their political positions. Additionally, social networks and support from women's groups and political organizations play crucial roles in their political communication strategies. Women's roles in Maluku politics are not limited to verbal and non-verbal communication but also include their ability to integrate local values and utilize their central societal roles to promote political agendas. These findings provide a significant contribution to the study of women's political communication, particularly in contexts that have been underexplored in both national and international literature. The research concludes that women's political communication in Maluku is a complex adaptation to the local socio-cultural context.

This study examines lecturers’ resistance to the development of digital technology in learning in the era of modern education. The purpose of the study was to identify barriers to explore factors that contribute to higher education resistance to the integration of digital technology in higher education. This method used a mixed methods approach , utilizing a survey to assess lecturers’ attitudes toward digital technology and interviews to provide deeper insights into personal experiences and perceived barriers. Data were analyzed using thematic analysis to identify common themes and patterns related to resistance with faculty members from various disciplines across institutions. The innovation in this study lies in a holistic approach that integrates faculty perspectives and institutional policies. And professional development and training on modern learning theories and the application of digital technologies in education. The results of this study underscore the need for tailored support and training initiatives to improve skills and confidence in the use of digital technologies so as to address specific issues and barriers identified by faculty by integrating technology into teaching towards effectiveness and can improve student learning experiences in this increasingly digital era.

Industrialization, while often driving economic growth, has led to significant environmental degradation, particularly in marginalized communities. These populations, already vulnerable due to socio-economic and geographic factors, bear the brunt of the environmental harm caused by industrial activities. This study explores the role of social-legal instruments in mitigating ecological inequality, focusing on their ability to reduce environmental burdens and empower marginalized communities in industrializing regions. A mixed-methods approach was employed, combining environmental data mapping and legal framework assessment. The study found that social-legal interventions, including rights-based advocacy, legal aid, and community participation, significantly reduced ecological disparities. By improving access to legal resources and fostering active community engagement in environmental governance, these interventions empowered vulnerable populations to advocate for their environmental rights. Positive correlations were found between the implementation of robust legal frameworks and reductions in pollution exposure, highlighting the effectiveness of integrating environmental and social protections. However, the study also identified several barriers to the effective implementation of these instruments, including political resistance, resource limitations, and unequal access to legal support. These challenges hinder the full realization of social-legal frameworks' potential. The study concludes with recommendations for policymakers to strengthen social-legal instruments by incorporating social equity into environmental regulations and improving the resources available to marginalized communities. Further research is needed to assess the long-term impacts of social-legal interventions and their scalability to other industrializing regions, with an emphasis on enhancing both ecological and social outcomes.

With the rapid increase in global population and the ongoing depletion of agricultural land, food security faces an escalating threat. CRISPR genetic engineering technology offers immense potential to enhance crop resilience and productivity. However, its application raises significant ethical concerns, both from a bioethical perspective and within the framework of Islamic values. This article examines core principles of bioethics and Islamic ethics to explore the morally conscious integration of genetic technology. Through a comprehensive literature review, it underscores the necessity of a collaborative approach involving scientists, policymakers, and religious leaders to establish ethical guidelines for its responsible use. The findings highlight the critical need to strike a balance between technological innovation and the preservation of moral principles. By adhering to ethical standards rooted in both modern bioethics and Islamic teachings, genetic technologies such as CRISPR can be harnessed to address food security challenges by improving crop productivity and fortifying resistance to diseases and extreme environmental stressors, without compromising moral integrity.

Abstract. Bureaucratic reform in Indonesia is an important agenda in improving government performance, especially in public services. Kerinci Regency, Jambi Province, faces various challenges in carrying out bureaucratic reforms, such as low capacity of civil servants, limited infrastructure, and resistance to change. Weber's bureaucratic theory, New Public Management (NPM), and the concepts of efficiency, effectiveness, and transparency are the theoretical framework for understanding the importance of bureaucratic reform. This study uses a qualitative descriptive approach with in-depth interview methods and direct observation. The results of the study show that Kerinci Regency has implemented bureaucratic reform policies, such as simplifying service procedures and using information technology. However, various obstacles such as the lack of ASN capacity and limited infrastructure hinder the implementation of reforms as a whole. The positive impacts identified are increased community satisfaction, transparency, and accountability of local governments. This research recommends increasing the capacity of civil servants, expanding the implementation of e-government, and strengthening service infrastructure to support more effective and sustainable bureaucratic reform. Thus, bureaucratic reform in Kerinci Regency can encourage public services that are more efficient, transparent, and responsive to the needs of the community.

This research discusses the central role of the Muslim community in resisting colonial powers in the Indonesian archipelago, focusing on colonization by the Dutch, Spanish, Portuguese, French, British, and Japanese. Islamic teachings, particularly the concepts of jihad, love for the homeland, and resistance to oppression, played a pivotal role in igniting the spirit of resistance. Islamic Sultanates such as Aceh, Demak, and Mataram actively engaged in the struggle, along with the leadership of scholars and the general population. With low literacy rates, the positive transformations during British colonization were limited in their full utilization by the local communities. Although Japan initially attempted to garner support by claiming liberation, it eventually proved to be a harsh colonizer with forced labor programs. This research employs the library research method to explore the dynamics of Muslim resistance against colonizers by utilizing literary sources.

The integration of digital transformation into government agencies' performance management has become essential in enhancing public service delivery, efficiency, and accountability. This study focuses on implementing the Electronic System for Government Agency Performance Accountability (E-SAKIP) in Indonesia as a case study of digital transformation. The research employs a qualitative approach with a case study design to explore the effectiveness, challenges, and impact of E-SAKIP on performance management. The findings indicate that E-SAKIP has significantly improved transparency and efficiency in government operations, reducing time and costs associated with performance reporting by up to 70%. However, challenges such as inadequate infrastructure, resistance to change, and insufficient training for government employees have hindered its full potential. The study underscores the need for ongoing support, including enhanced infrastructure, continuous training, and stronger leadership to ensure successful digital transformation. These insights offer valuable recommendations for further development of E-SAKIP and similar systems in other government contexts.

This study aims to redesign the superstructure of the Sambungrejo Bridge in Sidoarjo, which has a span length of 16 meters. The Sambungrejo Bridge originally used WF 700.300.15.28 steel girders and C 300.100.10.16.8 diaphragms,that are susceptible to corrosion, especially during floods. The redesign involves replacing the steel girder with a Prestressed Concrete I Girder (PCI Girder) H-900mm, 170mm thick, produced by WIKA Beton, known for its superior corrosion resistance and construction efficiency. The research methodology includes structural analysis using Robot Structural Analysis Professional (RSAP) software, calculation of prestressing forces, and the design of the prestressing cable layout. The results of this study demonstrate that the use of PCI Girder does not reduce the structural dimensions of the bridge but also proves to be more compatible with the flood water conditions at the site. The total cost required for implementing the new bridge superstructure design is Rp. 4.372.201.

The development of time has changed the types of diseases from infectious to non-communicable or degenerative such as asthma, cancer, stroke, chronic kidney disease, diabetes, and hypertension that are influenced by lifestyle, nutrition, and physical activity. Insulin resistance or lack of pancreas triggers diabetes mellitus, causing hyperglycemia that damages the nervous system and blood vessels. International Diabetes Federation predictions show an increase in diabetes mellitus cases worldwide, including in Central Java, which ranks second only to hypertension. Diabetes mellitus can be identified through blood glucose monitoring and symptoms include hunger, thirst, and frequent urination. Risk factors for diabetes include age, genetics, obesity, inactivity, hypertension, dyslipidemia, and poor nutrition. Prevention and management of diabetes can be done through family care that involves educators, counselors, and collaborators to help families manage the disease well. This study examines the nursing care of Mr. K's family. K with endocrine system disorders Diabetes Militus in Kalibuntu Village, Losari District, Brebes Regency, with the results of the patient's lack of understanding about diabetes and rarely doing exercise.

Background: Self-medication is defined as using medicinal products to treat the disorders or symptoms diagnosed by oneself, Self-Medication is common practice worldwide in both developed and developing countries, Regulations usually distinguish between prescription-only medicines (POM) and over the counter (OTC) drugs. inappropriate self-treatment can pose various risks including drug side effects, recurrence of symptoms, drug resistance, etc. the purpose of this study was to investigate the knowledge, attitude, and practice of medical students towards self-medication.  Subjects and Methods: A cross-sectional study was carried out among five stages that were selected by the simple random sampling for choosing the students. Data collections were performed from the beginning of March to October 2023. Data were collected with A four-part researcher questionnaire. It was designed to address the students’ knowledge, attitude, and practice. Statistical analysis was performed using Statistical Package for the Social Sciences 23 software. Results: Out of 462 questionnaires distributed, 445 questionnaires were completed; giving a response rate of 96.3%. According to the results, 310 (69.7%) students had carried out self-medication within the past one year. Common cold was the most common ailment treated with self-medication (73.9%) and antipyretics analgesics (64.5%) were the most used drugs. The primary information sources used by the students were their academic knowledge and books (47.4%). Health problems are not serious the most reason for self-medication in the study and lack of knowledge about medicine the highest causes for not taking medication. Conclusion: students’ knowledge of self-medication appears to be good and significantly high. As well self-medication was highly practiced among the students. Therefore, medical students should be viewed as important contributors to the public health care system, and future health professionals should be properly educated on good pharmacy practice and responsible self-medication.

Type 2 diabetes mellitus represents a persistent metabolic dysfunction marked by elevated blood glucose levels attributable to insulin resistance. Geriatrics pertains specifically to individuals aged 60 years and older. Managing diabetes mellitus necessitates intricate therapeutic interventions, often comprising single or combined pharmacological agents aimed at achieving euglycemia. The concurrent administration of multiple medications, termed polypharmacy, amplifies the likelihood of pharmacological interactions. This investigation endeavors to delineate potential drug interactions observed in geriatric inpatients afflicted with type 2 diabetes mellitus at Dr. Moewardi Regional General Hospital in Surakarta throughout the calendar year 2023. The study adopted a descriptive observational design employing a cross-sectional approach. Data collection was conducted retrospectively through purposive sampling based on the medical records of geriatric patients at Dr. Moewardi Regional General Hospital in Surakarta. Inclusion criteria encompassed patients aged 60 years and older diagnosed with type 2 diabetes mellitus who had been hospitalized. Exclusion criteria included incomplete or illegible medical records, patients diagnosed with anemia and hemoglobinopathies, and those who expired during treatment. The findings revealed that out of 100 patients, 96 experienced drug interactions. Most patients (47.00%) were aged between 66 and 74 years. Females constituted a larger proportion (51.00%) of the patient cohort. Among hospitalized patients, 83 (83.00%) were admitted for 2-6 days. A total of 70 patients (70.00%) were prescribed between 4 and 13 medications. The predominant severity level of drug interactions was moderate, comprising 1,017 cases (74.60%). Pharmacodynamic mechanisms accounted for most drug interactions observed, totaling 1,054 cases (77.30%).  

Tenascins are glycoproteins groups found in the extra-cellular matrix . The sphingolipidome in blood distinguished as a hundreds types of fats with many different essential chemical and physical properties. Insulin resistance is impaired biologic response of many target tissues to stimulation of insulin, and all tissues that have insulin receptors exposed insulin resistant. Materials and methods:  Sixty  sampling were participated, their ages ranged from (30-38) years. Biochemical measurements: insulin by AFIAS-10 , TN-X and sphingosine measured by kits by Sun Long Biotech – China.  Results:- the level of Tenascin-X, sphingosine and HOMA-IR in the obese group increase significantly (P<0.01) when compared to non-obese group. Cut-off  for Tenascin-X was 10.382pg./ml, for sphingosine was 10.93 ng./ml, and for HOMA-IR was 1.43 ng./ml. Conclusions: tenascin-X sphingosine and HOMA-IR  were related with obesity. Tenascin-X, Sphingosine and HOMA-IR were related to obesity