The development of Micro, Small and Medium Enterprises (MSMEs) has a strategic role in improving community welfare, especially in rural areas. This research aims to analyze the strengths, weaknesses, opportunities and threats (SWOT) faced by coconut processing MSMEs in Gesikharjo Village, Palang District. Data was collected through in-depth interviews with MSME actors, field observations, and document analysis. The research results show that the main strengths of these MSMEs are the availability of local raw materials and community support. However, weaknesses such as technological and management limitations are still challenges. Opportunities such as increasing demand for processed coconut products in local and national markets provide bright prospects, although threats such as price competition and global market fluctuations still need to be watched out for. Research recommendations include strengthening the managerial capacity of MSME players, product innovation, and collaboration with the government and private sector to create a sustainable business ecosystem.

This study aims to examine the role of Islamic accounting in the muamalah perspective as an important instrument in promoting sustainable economic growth. Islamic accounting, which is based on the principles of fairness, transparency, and benefit, plays a role not only in recording financial transactions, but also in ensuring business practices are in accordance with Islamic law. In the context of muamalah, principles such as the prohibition of riba, gharar, and maisir encourage the creation of a fair and stable economic system. This research uses the literature review method by analyzing relevant theories and previous research. The results of the study show that the implementation of Islamic accounting not only provides benefits for business people, but also contributes to sustainable development goals, such as poverty reduction, social welfare improvement, and environmental preservation. Thus, the application of Islamic accounting in muamalah practice can be a holistic solution to realize sustainable and equitable economic growth.

 Mojolaban is one of the sub-districts in Sukoharjo Regency, Central Java, which has 15 villages. The district has Mojolaban main health center, Jatimalang auxiliary health center and Kustati Clinic. Low back pain (LBP) is a disease that is widely suffered in Sukoharjo Regency, according to the Sukoharjo Regency Health Office, LBP sufferers amounted to 3,670 people from 2018-2022. LBP is one of the health problems that is often not taken seriously by the community, especially the elderly. Even though if left unchecked it can interfere with daily life and reduce quality of life. The purpose of this counseling is to prevent, promote health related to LBP with the target participants of the Matahari Elderly Posyandu located in Ds. Wirun Mojolaban. The measurement used in this activity is a pre-test and post-test questionnaire to measure the understanding of the elderly. The results of the questionnaire showed a good improvement with an average pre test and post test increase of 50%. For this reason, posyandu cadres always follow-up so that the elderly can do this exercise not only during counseling but also at home.

This study explores the utilization of LightGBM, a gradient-boosting framework, to classify the inhibitory activity of beta-secretase 1 inhibitors, addressing the challenges of Alzheimer's disease drug discovery. The study aims to enhance classification performance by focusing on overcoming the limitations of traditional statistical models and conventional machine-learning techniques in handling complex molecular datasets. By sourcing a dataset of 7298 compounds from the ChEMBL database and calculating molecular descriptors for each compound as features, we employed LightGBM in conjunction with a set of carefully selected molecular descriptors to achieve a nuanced analysis of compound activities. The model's efficiency was benchmarked against traditional machine-learning algorithms, revealing LightGBM's superior accuracy (84.93%), precision (87.14%), sensitivity (89.93%), specificity (77.63%), and F1-score (88.17%) in classifying beta-secretase 1 inhibitor activity. The study underscores the critical role of molecular descriptors in understanding drug efficacy, highlighting LightGBM's potential in streamlining the virtual screening process. Conclusively, the findings advocate for LightGBM's adoption in computational drug discovery, offering a promising avenue for advancing Alzheimer's disease therapeutic development by facilitating the identification of potential drug candidates with enhanced precision and reliability.

Kasindir Village is one of the villages in Jorlang Hataran District, Kabupaten Simalungun, Sumatera Utara. Kasindir Village is a village that carries out agricultural, livestock, and trade activities. Kasindir Village has great potential for developing MSMEs in the village. The development of MSMEs is considered capable of realizing a sustainable economy and supporting local governments in the Sustainable Development Goals (SDG's) program, especially in poverty and hunger eradication programs, sustainable economic growth, and employment. Community service implementers in Kasindir Village observed that MSME actors still require understanding and knowledge on utilizing information technology to advance their businesses. This includes packaging attractive products, providing the latest innovations, and promoting on social media to expand their market. MSME strategy development is able to realize the spirit of the SDGs. In this activity, the methods used to carry out community service activities are socialization and observation methods. Some of the problems faced by creative MSMEs in Kasindir Village include limited capital, raw materials, the use of very simple production equipment, and limited marketing media. Therefore, various parties, both government and private, need to provide support through sustainable business development programs.

The aim of this research is to describe the level of needs of the main character Kinara in the novel entitled Primerose by PenieJingga02. The problem raised in this research is how the character Kinara is able to fulfill Maslow's five levels of needs and whether Kinara is able to achieve the need for self-actualization at the highest level of Maslow's needs. The method used in the research is a descriptive qualitative literary psychology approach. literary psychology approach using the study of Abraham Maslow's humanistic theory. Maslow's five levels of needs that will be analyzed in the character Kinara are the psychological needs (physiological needs), the safety needs (needs for security), the belonging and love (needs for affection), the esteem needs (self-esteem needs) , the actualitation needs (actualization needs). This research shows that the main character Kinara has not been able to actualize herself because of the five needs there are two needs that have not been fulfilled, so the character Kinara has not been able to fulfill the last need, namely self-actualization.

Prevalensi   diabetes   tipe 2   terkait   usia   lansia   sampai   tahun   2030 mengalami peningkatan tajam karena diprediksi lebih dari 82 juta populasi lansia di negara berkembang menderita diebetes. Tipe 2 merupakan bentuk penyakit yang sering di lansia dan merupakan ancaman serius terhadap kesehatan karena terjadi komplikasi kronis. Tanda dan gejala diabetes pada lansia sering kali tidak jelas  dan  diagnosa  biasanya  terlambat.  Gejala  diabetes  dapat  muncul  tidak
spesifik  dan  tidak  pasti,  seperti  keletihan,  inkontinensia  urin,  atau  perubahan status mental seperti depresi, konfusi, dan apatis.
Beberapa ahli berpendapat bahwa dengan meningkatnya umur maka intoleransi terhadap glukosa juga meningkat. Peningkatan kadar gula darah pada lansia disebabkan oleh beberapa hal, yaitu fungsi pankreas dan sekresi insulin yang berkurang, perubahan karena lansia sendiri  yang berkaitan dengan resistensi insulin akibatnya kurangnya massa otot dan perubahan vaskuler, aktifitas fisik yang  berkurang,  banyak  makan  dan  kegemukan,  stress,  sering  menggunakan obat-obatan, dan adanya faktor keturunan.
Stres memicu  reaksi  biokimia  tubuh melalui  2  jalur,  yaitu  neural  dan neuroendokrin. Reaksi pertama respon stres  yaitu  sekresi  sistem  saraf  simpatis untuk  mengeluarkan  norepinefrin  yang menyebabkan    peningkatan    frekuensi jantung. Kondisi ini menyebabkan glukosa darah meningkat guna sumber energi untuk perfusi.  Peningkatan hormon  stres yang diproduksi dapat  menyebabkan kadar gula darah menjadi meningkat. Kondisi yang rileks dapat mengembalikan kotra-regulasi  hormon  stres  dan  memungkinkan  tubuh  untuk  menggunakan insulin lebih efektif.
Seseorang  yang  terkena  diabetes  akan  memerlukan  pengobatan  yang terus-menerus untuk  mengontrol  kadar gula  darah  dan  mencegah  komplikasi. Tapi ada pengobatan lain yang bisa dilakukan sendiri untuk membantu mencegah penyakit ini bertambah buruk. Stres yang tinggi yang dialami penderita dapat meningkatkan angka kesakitan dan kematian, sehingga dibutuhkan kemampuan penderita dalam melakukan perawatan diri   dengan memanajemen stress yang dialami.