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Kamila KH Djiha; Nuristha Febrianti; Adillah Imansri

Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi 2026 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Meeting the nutritional needs of pregnant women requires innovative strategies through the provision of healthy snacks with balanced nutritional value. Donuts are popular snack foods; however, they are generally made from wheat flour and have limited nutritional content. This study aimed to analyze the nutritional content and acceptability of donuts enriched with red bean flour and Banggai yam flour as a healthy snack for pregnant women. This experimental study employed a Completely Randomized Design (CRD) consisting of three formulations: F1 (35% red bean flour : 15% Banggai yam flour), F2 (40% : 10%), and F3 (45% : 5%), with two replications. Nutritional analysis included protein using the Kjeldahl method, fat using the Soxhlet method, and carbohydrate using UV-Vis spectrophotometry. Acceptability was evaluated using a hedonic test. Data were analyzed using ANOVA and the Kruskal–Wallis test. The results showed significant differences in protein, fat, and carbohydrate contents among formulations (p<0.05). The highest protein content was found in F3, the highest fat content in F2, and the highest carbohydrate content in F1. Acceptability did not differ significantly among formulations (p>0.05); however, F1 obtained the highest preference score. Donuts enriched with red bean flour and Banggai yam flour have the potential to be developed as a healthy local food–based snack for pregnant women.

Agnes Rantesalu; Hardianti Hardianti; Adillah Imansari

Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi 2026 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Background: The prevalence of Chronic Energy Deficiency (SEZ) of pregnant women nationally is still 16.9%, and anemia reaches 27.7%, so the development of local food-based Supplementary Feeding (PMT) is needed. Brownies with the substitution of red spinach as a source of iron and purple sweet potato flour as an energy source have the potential to be developed as an alternative to PMT. This study aims to determine the acceptability and nutritional content of red spinach brownies with the addition of purple sweet potato flour as an interlude food for pregnant women. Method: Design using the Complete Random Design (RAL) method. The formulation of making brownies consists of three treatments with a comparison between (red spinach pureee and purple sweet potato flour) as follows: F1 (50:50), F2 (60:40), and F3 (40:60). The acceptance test was conducted using a hedonic test of color, aroma, taste, and texture on 30 semi-trained panelists. Analysis of nutritional content includes moisture content (thermogravimetry), ash content (dry ashing), protein (Kjeldahl), fat (Soxhlet), carbohydrates (by difference), and Fe (Atomic Absorption Spectrophotometry). The data were analyzed using the Kruskal-Wallis test. Research Results: The acceptability test showed that there was no significant difference between the formulations. The F3 formulation with a ratio of 40% red spinach pureee and 60% purple sweet potato flour obtained the highest preference value and was determined as the best formulation. The nutritional content of the F3 formulation includes protein 10.447%, fat 8.047%, carbohydrates 1.5579%, Fe 0.0005%, moisture content 20.68%, and ash content 1.4875%. Conclusion: There was no significant effect of each formulation on the acceptability of Brownis Suggestion: It is hoped that the next researcher can improve product formulation and processing processes to maintain and increase iron (Fe) levels in brownies.

Hikmatullah Hikmatullah; Adillah Imansari; Masfufah Masfufah

Jurnal ilmu Kesehatan Umum 2026 Asosiasi Riset Ilmu Kesehatan Indonesia

Background: Pentol is a round-shaped snack that is popular with elemtary school children with a savory taste, affordable price, and easy to find in the school environment. However, uncontrolled consumption of pentol raises concerns about fat and sodium chloride (NaCl) content. Objective: This study aims to determine the levels of fat and NaCl contained in pentol snacks sold at Tondo Urban Village Elementary School, PaluCity. Method: This study used a Complate Random Design (RAL) on five pentol samples in five elementary school in Tondo Village, with two repetitions. Fat content was analyzed by the Soxhlet method, While sodium chloride (NaCl) content was analyzed by Mohr titration. The data were analyzed using the Kruskal-Wallis test. Findings: The fat content in five pentol sampels at Tondo Urban Village Elementary School ranged from 2,16-4,75% (maximum SNI limit of 10%), while sodium chloride content was 1,55-2,15% (maximum SNI limit of 2,5%). Statistical tests (p=0,4>0.05) showed no significant difference between samples. Although still below the SNI limit, the fat and sodium content is quite high for school children’s snacks. Conclusion: The fat and NaCl content of pentol sancks at Tondo Urban Village Elementary School, Palu City is still below the SNI limit, but the consumption of these snacks need to be limited. Implications: it is hoped that there will be further researchers who analyzed carbhohydrates, proteins and other additives such as preservatives in pentol snacks.        

Miftakhul Rokhmah; Amanda Rafina Modesty; Auliya Ika Putri; Salsabiila Wina Delia; Adelia Girlani Bria +7 more

Jurnal Riset Ilmu Farmasi dan Kesehatan 2026 Asosiasi Riset Ilmu Kesehatan Indonesia

The Soxhlet extraction method uses repeated heating and solvent circulation to separate substances from mixtures, producing more extract faster than maceration with less solvent. However, this method requires pure solvents and is not suitable for thermolabile compounds as they can be degraded by heat. Soxhlet extraction is more effective for limited quantities of dry and fine herbal materials. This method is widely used to extract phytochemical compounds such as flavonoids, tannins, and curcumin, and has potential in cosmetic raw materials, herbal medicines, and antioxidant products. Although it uses more energy, this technique is efficient and continuous. Modern innovations such as combining it with Ultrasonic Assisted Extraction (UAE) or environmentally friendly microextraction are expected to increase extraction efficiency while reducing the use of organic solvents. Modifications to Soxhlet, including automation and assistive technologies such as high pressure, ultrasound, and microwaves, open up opportunities for commercialization and further research with more optimal results and more practical operations. The modified Soxhlet is considered a “panacea” in extraction due to the significant performance improvements achieved.

Amertaningtyas, Dedes; Amalia, Alvina Wahyu; Evanuarini, Herly; Susilo, Agus; Jaya, Firman +1 more

JAPSI (Journal of Agriprecision and Social Impact) 2025 CV. Komunitas Dunia Peternakan

This study aimed to evaluate the effect of bee pollen addition on the chemical composition of cow’s milk–based jelly candy. Bee pollen is a natural product rich in proteins, minerals, and bioactive compounds, which may enhance the nutritional value of food products. The research was conducted at the Dairy Technology Laboratory, Department of Animal Product Technology, Faculty of Animal Science, Universitas Brawijaya, from June to August 2025. The research method used was a laboratory experiment using Complete Randomized Design (CRD) ANOVA with 4 treatments and 4 replications. If different results were obtaindes between treatments, Duncan’s Multiple Range Test (DMRT) was continued. Four treatments were applied: T0 (control, without bee pollen), T1 (6%), T2 (12%), and T3 (19%). The results demonstrated that bee pollen supplementation had a highly significant effect (P<0.01) on the protein content (Kjeldahl method), moisture content (Gravimetri method), ash content (Dry Ashing method), and carbohydrate content (By Different method), but showed no significant effect (P>0.05) on fat content (Soxhlet method). Protein content increased from 16.83% to 19.30%, moisture content increased from 29.56% to 34.30%, while ash content exhibited a fluctuating trend. Conversely, carbohydrate content decreased from 52.90% to 45.19%. Overall, the addition of bee pollen improved the nutritional quality and functional potential of milk-based jelly candy, particularly as a natural source of protein and minerals.

Eprariana Eprariana; Fiona Maulidia; Siti Nor Adidah; Chiena Nazerina Yoshi4; Raida Raida +2 more

Jurnal Pendidikan Kimia, Fisika dan Biologi 2025 Asosiasi Riset Ilmu Pendidikan Indonesia

This study aims to analyze the differences between various extraction techniques and their relationship to the yield and biological activity of phytochemical compounds derived from natural materials. A systematic literature review was conducted by analyzing relevant and reliable scientific publications published within the last five years. The findings indicate that extraction methods such as maceration, soxhletation, microwave-assisted extraction (MAE), and ultrasound-assisted extraction (UAE) demonstrate varying levels of effectiveness depending on the type of material, solvent polarity, extraction temperature, and duration of the process. Modern extraction methods, particularly sonication, MAE, and UAE, have been shown to produce higher yields with enhanced biological activity while offering greater efficiency in terms of reduced time and solvent consumption. On the other hand, conventional techniques such as maceration and soxhletation remain relevant, particularly for thermolabile compounds that are sensitive to high temperatures. The selection of an appropriate extraction method plays a crucial role in obtaining high-quality extracts that can serve as potential raw materials for phytopharmaceuticals, functional foods, dietary supplements, and other natural products. This review not only highlights the advantages and limitations of each technique but also emphasizes the importance of aligning method selection with specific research objectives and compound characteristics. Overall, this study provides a theoretical foundation for future experimental research and serves as an initial guideline for determining extraction strategies based on efficiency, effectiveness, and sustainability.

Amaliya Bunga Dwiyanti; Devira Niken Putri Ferdinand; Mifta Dewi; Musa’adah Musa’adah; Noor Mila Wati +1 more

Jurnal Riset Rumpun Ilmu Kedokteran 2025 Pusat riset dan Inovasi Nasional

Extraction is a crucial process for obtaining active compounds from natural materials, such as medicinal plants, spices, and other biomass. The success of the extraction process is greatly influenced by the method used, as each method has its own mechanism, efficiency, and yield. This study compared seven commonly used extraction methods: maceration, percolation, infusion, soxhletation, reflux, Ultrasound-Assisted Extraction (UAE), and Microwave-Assisted Extraction (MAE). Based on data collected from various scientific journals, it was found that modern methods such as UAE and MAE are capable of producing higher yields than conventional methods. Furthermore, both methods are more efficient in terms of extraction time and solvent usage, making them more environmentally friendly and suitable for industrial-scale applications. However, conventional methods such as maceration and percolation still play an important role, especially in initial research or in laboratories with limited equipment. For example, maceration is easy to perform, does not require high energy, and is suitable for heat-sensitive materials. Other factors that influence extraction results include the type of solvent, temperature, time, and the characteristics of the natural material itself. Therefore, the choice of extraction method must be tailored to the research objectives, the type of compound to be extracted, and the availability of resources and equipment. Combining several methods can also be considered to improve the efficiency and quality of the extraction results. It should be emphasized that extraction yield is influenced not only by the method, but also by the type of material, solvent, temperature, time, and particle size. Therefore, the choice of extraction method must be tailored to the nature of the material, the type of target compound, as well as the objectives and availability of resources. In some cases, a combination of extraction methods can also be used to increase efficiency and obtain optimal results.

Eprariana, Eprariana; Fiona Maulidia; Siti Nor Adidah; Chiena Nazerina Yoshi; Raida Raida +2 more

Jurnal Pendidikan Kimia, Fisika dan Biologi 2025 Asosiasi Riset Ilmu Pendidikan Indonesia

This study aims to analyze the differences in various extraction techniques and their relationship to the yield and biological activity of phytochemical compounds from natural materials. The research was conducted through a systematic literature review from various reliable scientific sources over the last decade. The results indicate that extraction methods such as maceration, soxhlet extraction, microwave-assisted extraction (MAE), and ultrasound-assisted extraction (UAE) have varying effectiveness. The effectiveness of these methods is highly dependent on the type of material, solvent used, and process parameters such as temperature, time, and solvent-to-material ratio. Modern extraction methods such as sonication, MAE, and UAE tend to produce higher yields and better biological activity. These modern methods have the advantage of being more time-efficient and requiring fewer solvents, thus allowing the extraction of active compounds more optimally. Additionally, technologies like microwave and ultrasonic waves help break down the cell walls of natural materials, enhancing the release of phytochemical compounds more effectively and rapidly. However, conventional methods such as maceration and soxhlet extraction remain relevant, especially for materials containing thermolabile compounds that may degrade at high temperatures. These methods are still preferred to maintain the stability of active compounds sensitive to thermal degradation. Choosing the appropriate extraction method is crucial in producing high-quality extracts that can potentially be used as raw materials for phytopharmaceuticals, supplements, or other natural products. This study provides a strong theoretical foundation for further experimental research and guidance in selecting extraction methods based on the required efficiency and effectiveness for industrial applications. Thus, this study contributes to the development of more efficient and high-quality natural products.

Siddeek Bakr Mar'ie; Suha Saeed Rashid Al-Tikrit; Ayad C. Khorsheed

International Journal of Health and Medicine 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

This study investigated the phytochemical screening and antibacterial activity against various microorganisms including E. coli, Staphylococcus aureus, Klebsiella pneumoniae, Enterococcus faecalis, and Candida albicans. Active compounds were isolated and identified from Aleppo Oak Gallnut, obtained from the Iraqi plant Quercus Infectoria L. Plant extracts were prepared using a continuous extraction apparatus, Soxhlet, with a successive solvent system based on polarity differences, including petroleum ether (60-80°C), ethanol (78°C), and hot aqueous extracts. Acid hydrolysis was performed on the raw ethanol and hot water extracts to obtain free phenolic compounds, including Gallic acid, Apigenin, Rutin, Kaempferol, Chlorogenic acid, and Caffeic acid, using high-performance liquid chromatographic (HPLC) techniques. The inhibitory activity of Aleppo Oak Gallnut extracts (Ethanol and Hot Aqueous) after acid hydrolysis was tested using four concentrations (25%, 50%, 75%, 100%) against various microorganisms. The Ethanol extract exhibited a significant inhibitory effect on Enterococcus faecalis. The Hot Aqueous extract showed a modest inhibitory effect on Enterococcus faecalis. The Ethanol extract demonstrated strong inhibition against Klebsiella pneumoniae. The Hot Aqueous extract at 100% and 75% showed high inhibition. The Ethanol extract exhibited significant inhibitory effects against Staphylococcus aureus at 100%. The Hot Aqueous extract at 75% and 100%  demonstrated weaker inhibition against Staphylococcus aureus. The Ethanol extract demonstrated weaker inhibition against E. coli, and the Hot Aqueous extract showed no effect at 50%  and 25%, and slight inhibition at 100%  and 75%. For Candida albicans, the Ethanol extract showed minimal inhibition at all concentrations and no effect at 25%. The Aqueous extract had a slight effect at 100%  and no inhibition at 75%, 50%, and 25%.

Rianto Wibowo; Amirul Haq Rohmatullah

Prosiding Seminar Nasional Ilmu Teknik 2024 Asosiasi Riset Ilmu Teknik Indonesia

Tanjung Jati B Unit 3 & 4 Steam Power Plant (PLTU) is a steam power plant that uses coal as fuel. Burning coal produces exhaust emissions containing sulfur dioxide (SO2) which is dangerous for the environment. To overcome this, PLTU Tanjung Jati B Units 3 & 4 uses Flue Gas Desulphurization (FGD) to reduce SO2 emissions. This research aims to analyze the factors that cause FGD failure in reducing SO2 emissions, formulate efforts to overcome FGD failure and improve its performance, and develop a method for evaluating the effectiveness of FGD in reducing SO2 emissions. The research method used is literature study, primary data collection through observation and interviews, and data analysis. The research results show that the factors that cause FGD to fail in reducing SO2 emissions are blockage of the spray pipe and header pipe, blockage of the tray, and a decrease in the performance of the booster fan and absorber recirculation pump. The method for evaluating the effectiveness of FGD in reducing SO2 emissions is by analyzing de-Sox efficiency, flue gas flowrate and temperature, pressure drop, and ARP discharge pressure. Keywords: PLTU, FGD, SO2 emissions, de-Sox efficiency, flue gas flow rate, pressure drop, ARP discharge pressure. The method for evaluating the effectiveness of FGD in reducing SO2 emissions is by analyzing de-Sox efficiency, flue gas flowrate and temperature, pressure drop, and ARP discharge pressure.

Chaterine Juliana Sitorus; Greace Astrid Rotua Hutabarat

Konstanta : Jurnal Matematika dan Ilmu Pengetahuan Alam 2024 International Forum of Researchers and Lecturers

The study aimed to investigate the alkaloid content in cinnamon (Cinnamomum burmannii) powder using the Soxhlet extraction method. Alkaloids are organic chemical compounds widely found in nature as secondary metabolites in both plants and animals. They possess a cyclic structure containing one or more basic nitrogen atoms, conferring unique basic properties. The research was conducted to provide a deeper understanding of the potential utilization of plant-derived alkaloids, particularly from cinnamon, in drug development. The study sought to determine the color of the precipitate formed in the extraction solution after the addition of Mayer's reagent and to investigate the effect of the number of Soxhlet extraction cycles on the color of the ethanol used in the research with cinnamon samples. The findings from this study contribute to the exploration of the alkaloid content in cinnamon and its potential applications in pharmaceutical development.

Elsan Septiani; Ageng Saepudin Kanda S

Jurnal Manuhara : Pusat Penelitian Ilmu Manajemen dan Bisnis 2024 Asosiasi Riset Ilmu Manajemen Kewirausahaan dan Bisnis Indonesia

This study aims: to describe the composition and behavior of exhaust gases of motorized vehicles that can have an impact on human health. Based on the results of a theoretical study of various information that the main pollutants in motor vehicle exhaust gases are carbon monoxide (CO), hindrocarbon compounds, nitrogen oxides (NOx) and sulfur (SOx), and dust particulates including lead (PB). Chemical reactions in the atmosphere sometimes take place in a long and complex reaction chain, and produce an end product that can be more active or weaker than the original compound. Motor vehicle exhaust gases which have an impact on health are classified as follows; (1). Pollutants which mainly interfere with the respiratory tract. Included in this group are sulfur oxides, particulates, nitrogen oxides, ozone and other oxides, (2). Pollutants that cause systemic poisons, such as monoxide and lead / lead hydrocarbons, (3). Pollutants suspected of causing cancer such as hydrocarbons, (4). Conditions that interfere with comfort such as noise, street dust, etc. So the conclusion is that in anticipating the negative impacts caused by motor vehicle exhaust gases, the role of the government in setting several regulations and policies in the environmental field is needed, where every business or activity is prohibited from violating the quality standards and standard criteria of environmental damage set by government.

Yunisa Yunisa; Suhaera Suhaera; Shinta Sari

The Journal General Health and Pharmaceutical Sciences Research 2023 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Karimun Regency, Riau Archipelago Province has an ocean with abundant marine life and has not been used optimally. Bronok (Acaudina malpadioides) is a type of marine biota that lives in muddy coastal areas. Bronok on Karimun Island is consumed fresh and is believed to reduce joint pain. This study aims to determine the content of water, ash, fat, protein and carbohydrates in bronok (Acaudina malpadioides). The proximate analysis includes the water content test using the thermogravimetric method, the ash content using the dry ashing method, the fat content method (Soxhlet), the protein content method (Kjeldhal), and the carbohydrate content method (By different). Bronok that has been analysed for proximate content is found to be present at 16% water content, 29,2% ash content, 5,39% fat content, 11,25% protein content and 38,16% carbohydrate content.

Juliano Tigana Ottu

JURNAL WILAYAH, KOTA DAN LINGKUNGAN BERKELANJUTAN 2022 Fakultas Teknik Universitas Cenderawasih

Kota Kupang merupakan ibukota Provinsi Nusa Tenggara Timur (NTT) dengan luas wilayah sebesar 180,27 km². Letak Kota Kupang yang strategis, sebagai Ibukota Propinsi NTT menjadi daya tarik tersendiri bagi warga pendatang dari daerah-daerah lain. Jumlah penduduk di Kota Kupang pada tahun 2017 sebanyak 412.708 jiwa. Pertumbuhan penduduk Kota Kupang dalam waktu 8 tahun sejak tahun 2009 sekitar 121.708 jiwa atau sekitar 15.000 jiwa/tahun. Pertumbuhan penduduk di Kota Kupang memicu terjadinya peningkatan jumlah kendaraan yang berujung pada peningkatan pencemaran udara dari sektor transportasi. Sampai pada bulan Oktober tahun 2018 jumlah kendaraan di Kota Kupang tercatat sepeda motor sebanyak 25.362 unit dan mobil sebanyak 5.357 unit. Perkembangan kota dan pertumbuhan penduduk juga akan mengakibatkan konversi terhadap lahan-lahan hijau yang menyebabkan lahan untuk ruang terbuka hijau (RTH) semakin sempit. Penelitian ini menggunakan analisis deskriptif kuantitatif untuk mengetahui luas RTH yang dapat mereduski total cemaran yang terjadi diwilayah BWK II Kota Kupang. Hasil penelitian menunjukan bahwa ketersediaan RTH di Kota Kupang hanya sebesar 17,10% yang terdiri dari RTH Publik sebesar 13,11% dan RTH Privat sebesar 3,99%, total kebutuhan RTH di Kota Kupang agar dapat memenuhi syarat yang telah diatur dalam undang-undang yaitu sebesar 5408,1 Ha yang terdiri dari RTH Publik membutuhkan 6,88% atau 1241,49 Ha dan RTH Privat membutuhkan 6.00% atau 1082,7 Ha. Total emisi yang terjadi di sepanjang Jalur Hijau BWK II Kota Kupang sebesar 2727,5 Kg/Jam dan kemampuan daya serap RTH eksisting sebesar 1301,34 dan masih menyisakan sisa emisi sebesar 1426,16 Kg/jam, sehingga membutuhkan tambahan RTH sebesar 10,3Ha untuk dapat menyerap seluruh emisi yang dihasilkan dari sektor transportasi pada kawasan jalur hijau BWK II. Beberapa Strategi yang dapat dilakukan untuk memenuhi kebutuhan RTH di Kota Kupang adalah (1) Memadatkan RTH jalur hijau dengan cara memanfaatkan lahan kosong yang terdapat pada jalur hijau untuk menanam jenis-jenis vegetasi yang memiliki daya serap tinggi. (2) dengan menggantungkan spesies tanaman penyerap emisi pada pohon-pohon yang ada pada RTH jalur hijau dan menerapkan metode vertical garden,Roof garden dan tree adoption.