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Pain is a prevalent issue frequently seen by pregnant women in their third trimester, attributable to physiological, biomechanical, and psychological alterations during gestation. Non-pharmacological pain management is essential as a secure alternative to enhance the comfort of pregnant women. Perinatal Yoga and Relaxation Techniques are two commonly endorsed non-pharmacological therapies; yet, comparative analyses of their efficacy remain scarce, particularly within primary health care settings. This study is to evaluate the efficacy of Perinatal Yoga against Relaxation Techniques in alleviating pain among pregnant women in their third trimester at the Bongo II Community Health Centre. The research employed a quasi-experimental design with a two-group pretest-posttest methodology. The sample comprised 38 pregnant women in their third trimester, categorized into two groups: 19 participants in the Perinatal Yoga group and 19 participants in the Relaxation Techniques group. The Numeric Rating Scale (NRS) was utilized to assess pain severity prior to and following the intervention. A paired t-test was utilized for intra-group differences, whereas an independent t-test was employed to assess inter-group efficacy.The findings indicated that both Perinatal Yoga and Relaxation Techniques markedly diminished pain intensity in pregnant women throughout their third trimester (p<0.001). The decrease in pain in the Perinatal Yoga group was statistically significant compared to the Relaxation Technique group (p<0.05). This study concludes that Perinatal Yoga is superior than Relaxation Techniques in alleviating pain in pregnant women during their third trimester. Perinatal Yoga is indicated as an effective and practical non-pharmacological technique in antenatal treatment inside primary health facilities.

Dysmenorrhea, which is common in adolescent girls, is a painful menstrual cycle that frequently interferes with daily activities, both in the classroom and in social situations. Dysmenorrhea is a common condition that needs particular care as a reproductive health concern, notably among young people. Both pharmacological and non-pharmacological approaches can be used to treat dysmenorrhea. The use of warm water compresses is a simple, inexpensive, and effective non-pharmacological approach. By increasing blood vessel dilatation, enhancing blood circulation, lowering muscular tension, and lowering pain perceptions, warm water compresses aid in alleviating dysmenorrhea symptoms. The objective of this study is to assess the impact of warm compresses on the severity of dysmenorrhea pain scales in teenage girls at the Buntalo Community Health Center. The design of this trial was pre-experimental, using a one-group pretest-posttest technique. Using a purposive sampling method, a sample of 20 respondents was chosen. The Wilcoxon test was used to conduct the data analysis. According to the data, there was a statistically significant reduction in pain intensity, with a Z value of -4.065 and a p-value of 0.000 (p < 0.05). The average pain scale decreased from 2.95 to 1.80. Based on these findings, it is reasonable to conclude that warm water compresses are helpful in alleviating dysmenorrhea pain in young women. One of the suggestions for non-pharmacological treatments to help alleviate dysmenorrhea symptoms in adolescents is anticipated to be the outcome of this research.

Low back pain is a common complaint among pregnant women in the second and third trimesters due to biomechanical and hormonal changes. Non-pharmacological interventions like prenatal exercise are believed to be effective, though evidence from controlled trials is limited. This study aimed to evaluate the effectiveness of prenatal exercise in reducing low back pain intensity. A quasi-experimental pretest–posttest control group design was used with 30 pregnant women (15 in the intervention group, 15 in the control group), selected by purposive sampling. The inclusion criteria were gestational age of 20–36 weeks, no medical contraindications, and willingness to participate. The intervention group performed prenatal exercises twice a week for 8 weeks (45 minutes per session), while the control group received health education without physical exercise. Pain intensity was measured using the Visual Analogue Scale (VAS). Data analysis was conducted using paired t-test, independent t-test/Mann–Whitney, and ANCOVA to control for age, parity, and BMI. Both groups had homogeneous baseline characteristics (p > 0.05). The intervention group’s pain score decreased from 6.9 ± 1.1 to 3.6 ± 1.0 (Δ = -3.3; p < 0.001), while the control group’s pain score decreased from 6.8 ± 1.2 to 6.3 ± 1.1 (Δ = -0.5; p = 0.09). The difference in pain reduction between groups was significant (p < 0.001). ANCOVA confirmed that prenatal exercise was significantly effective after adjusting for confounders (β = -2.8; p < 0.001). Prenatal exercise is an effective, safe, and affordable intervention for reducing low back pain in pregnant women.

Patients undergoing surgery often experience preoperative anxiety due to concerns about the outcome, pain, and the risk of complications. Uncontrolled anxiety can affect the patient's physiological and psychological condition and slow the recovery process. One non-pharmacological effort that can be used to reduce anxiety is the finger-holding relaxation technique, a simple method that can help balance emotions and provide a sense of calm. To determine the effect of the finger-holding relaxation technique on changes in preoperative anxiety levels in patients at Batang Regional General Hospital. Method: This study used a descriptive case study approach. The respondents were four patients who were about to undergo surgery and were experiencing anxiety. The intervention was conducted for approximately 15 minutes using the finger-holding relaxation technique. Anxiety levels were measured before and after the intervention using the Hamilton Anxiety Rating Scale (HARS). All respondents experienced a decrease in anxiety levels after the intervention. The average reduction in anxiety scores was 7.25 points. Before the intervention, two patients experienced severe anxiety and two patients experienced moderate anxiety. After the intervention, two patients experienced mild anxiety and two others experienced a decrease to moderate levels. This indicates that finger-holding therapy has a positive effect on reducing preoperative anxiety in patients. The finger-holding relaxation technique has been proven effective in reducing preoperative anxiety in patients. This intervention can be used as a simple, safe, and easy-to-implement non-pharmacological therapy alternative for nurses to improve patient psychological comfort.

Research at Diponegoro University found that 66.7% of 63 respondents experienced neck pain due to using a laptop for more than 4 hours. Prolonged laptop use can negatively impact health from an ergonomic perspective, as the recommended maximum usage is 2 hours per day. However, students often maintain non-ergonomic positions for extended periods. This study aimed to determine the relationship between laptop use and neck pain among Diploma Three Nursing Students at Abulyatama University, Aceh. The research utilized an analytical, cross-sectional design, with a population of 556 students and a sample of 85 students, selected through purposive random sampling. The research was conducted at Abulyatama University from May 15 to June 2, 2025, and data was collected using a questionnaire with a Numeric Rating Scale. Analysis involved both univariate and bivariate methods using the Chi-Square test. The results showed that among 85 respondents, 44 (95.7%) experienced moderate pain, 8 (40.0%) had mild pain, and 8 (42.1%) reported severe pain. Statistical analysis indicated a significant correlation (p=0.000) between laptop use and neck pain. In conclusion, there is a strong relationship between laptop use and complaints of neck pain among university students. The research is expected to raise student awareness about the health risks associated with prolonged and improper laptop use, encourage better posture, and serve as a reference about limiting laptop use and improving ergonomics.

Sectio caesarean (SC) is a major surgical procedure performed to save the mother and baby when normal delivery is not possible. However, this procedure may cause postoperative complications such as impaired physical mobility due to pain, muscle weakness, and anesthesia effects. These limitations can delay the healing process, increase the risk of infection, and reduce the mother's self-care ability. One effective non-pharmacological intervention to accelerate recovery is early mobilization through Range of Motion (ROM) exercises. This case study aims to analyze the effectiveness of early mobilization (ROM) intervention on improving mobility and reducing pain in post-sectio caesarean mothers. The study was conducted in June 2025 at RSUD Kajen with three respondents who underwent SC for different obstetric indications (postterm, CPD, and severe preeclampsia). The research design used a descriptive case study with pre–post intervention approach. The results showed that after performing ROM exercises gradually from six hours post SC, pain intensity decreased from a scale of 7–8 to 1–3 within three days. Mobility ability improved from only being able to turn sideways to sitting and walking with assistance. Respondents also showed increased motivation and independence in self-care activities. In conclusion, early mobilization (ROM) intervention is effective in accelerating recovery for post-sectio caesarean mothers. This intervention helps reduce pain, improve circulation, strengthen muscles, and enhance psychological adaptation. Early mobilization should be applied as part of routine nursing interventions in the postpartum ward.

Sectio caesarean surgery is a surgical procedure that can effectively prevent ma- ternal and newborn deaths when used for reasons of medical indications. Post operative sectio caesarean can pose several risks of complications, one of which is pain and surgical wound infection. Non pharmacological approach aromatherapy as a complementary therapy to reduce postpartum pain. This case study aims to analyze the influence aromatherapy lavender on reducing pain levels in post sectio caesarean mothers by using the case study method pre and post test. The case study was carried out in 25 May 2025 – 07 June 2025. This type of case study is descriptive with the number of subjects used, namely three post partum mothers in the RSUD Batang private sector with pain assessment using a questionnaire Numeric Rating Scale (NRS). The results of the case study showed a change in pain intensity from a scale of 6-7 to a scale of 4-5. This shows an influence aromatherapy lavender on reducing pain levels in postpartum mothers caesarean section Giving innovation aromatherapy can be used as an independent nursing in- tervention so that it can be applied to patients regularly.

Knee osteoarthritis is one of the most prevalent musculoskeletal disorders in the elderly, characterized by progressive degeneration of articular cartilage, chronic pain, joint stiffness, and reduced functional capacity. In Indonesia, the prevalence of knee osteoarthritis is notably high, affecting over 30% of individuals aged above 60 years. This condition leads to significant health burdens, impaired quality of life, and increased economic costs. Non-pharmacological management strategies such as hydrotherapy and quadriceps exercise are widely recommended to relieve pain and improve joint function. Hydrotherapy utilizes the physical properties of water including buoyancy, hydrostatic pressure, viscosity, and warmth to reduce joint loading, enhance circulation, and promote relaxation. Quadriceps exercise, on the other hand, focuses on strengthening the quadriceps muscle to stabilize the knee joint, thereby reducing pain and improving functionality. The combination of these two interventions is expected to provide greater benefits than a single modality. Research Design: This study employed a quasi-experimental design with a one-group pre-post test approach on 12 elderly respondents with knee osteoarthritis at OSF Magdalena Daemen BSB Convent. Pain was measured using the Visual Analogue Scale (VAS) before and after the intervention, which consisted of hydrotherapy and quadriceps exercise administered twice a week for four weeks. Results: The findings showed a decrease in the mean pain score from 4.42 to 3.08, with the Wilcoxon test yielding p = 0.001 (p < 0.05), indicating a significant difference in pain levels before and after the intervention. Conclusion: The combination of hydrotherapy and quadriceps exercise is effective in reducing pain in patients with knee osteoarthritis.

Background: Indonesia, as an agrarian country, has a large workforce engaged in physically demanding activities that increase the risk of myofascial pain. The prevalence of myofascial pain syndrome (MPS) in the upper trapezius muscle in Indonesia reaches 40% annually, with a higher rate in women. This condition often causes complaints in the neck, shoulders, and lower back, leading to a decline in quality of life. Various management strategies exist, but many are less effective in the long term and carry potential side effects. Lidocaine, as a local anesthetic, offers an alternative therapy due to its simple procedure, affordable cost, rapid effect, and good safety profile; therefore, its effectiveness in managing myofascial pain needs to be evaluated. Methods: This study was an observational research with a prospective cohort design conducted at PKU Muhammadiyah Gamping Hospital. Patients with myofascial pain who received lidocaine injections were followed for 4 weeks, and pain intensity was measured using the Numeric Rating Scale (NRS) to assess the relationship between lidocaine administration and pain reduction. Results: The study showed that lidocaine injection was effective in significantly reducing myofascial pain. The Wilcoxon Signed Rank Test produced negative Z values with p = 0.000 (<0.05) for all comparisons from pretest to the fourth week. The Friedman test also indicated significant differences between weeks (χ² = 9.731; p = 0.021), with optimal pain reduction observed in the second week. Although lidocaine provided significant analgesic effects, its effectiveness tended to decrease in subsequent weeks, indicating a short-term effect that should be combined with other interventions for sustained outcomes. Conclusion: Lidocaine injection proved effective in reducing pain among patients with myofascial pain syndrome, with the most optimal reduction occurring in the second week after therapy. The dominant factors influencing the outcomes were the relatively short duration of lidocaine’s action and individual variability in response. This implies that lidocaine can be used as an effective initial therapy, but should be combined with other interventions such as physiotherapy or activity modification to achieve more stable and sustainable pain management.

The World Health Organization (WHO) reported in 2019 that 40 million people worldwide require palliative care, including those with cardiovascular disease (38%), cancer (34%), chronic lung disease (10.3%), AIDS (5.7%), and diabetes (4.6%). Palliative care aims to improve the quality of life of patients and families facing life-threatening illnesses by managing pain and physical, psychological, social, and spiritual problems. The main goal of this care is to reduce suffering and help patients cope with the limitations imposed by illness. The principles are to respect life, consider death a normal process, neither hasten nor delay death, and provide support until the end of life. This study aims to determine whether knowledge can influence the level of self-efficacy of nursing students at Awal Bros University. Using a correlational quantitative method, data were collected through the Palliative Care Quiz for Nursing and Self-efficacy Palliative Care Scale questionnaires. The results of the study show a significant relationship between knowledge and self-efficacy among students with p<0.005. These findings can be used as a basis for learning to improve the understanding of nursing students, especially in the context of palliative care, which is important for the quality of health services in the future.

Labor is a complex interaction between psychological and physiological drives in women. (90%) delivery is accompanied by pain. In the active phase there is an increase in the intensity and frequency of contractions, so that the peak pain response is in this phase. Pain and soreness during labor are basically caused by strong contractions during labor. Breathing relaxation techniques can control pain by minimizing sympathetic activity in the autonomic nervous system. This study aims to determine the effect of deep breathing relaxation techniques on reducing labor pain in the first active phase. The type of design in this study is pre-experimental with The number of samples was taken according to the Accidental Sampling technique, samples were taken when patients went to the Andra Agustiana PMB Clinic with a minimum of 30 respondents. The data collection technique used a questionnaire sheet and a Numeric Rating Scale (NRS) pain scale. Data analysis used the Wilcoxon test. The results showed that before being given the breathing relaxation technique, most respondents experienced severe pain or pain levels on a scale of 7-10, namely 25 respondents (71.4%) and after being given deep breathing relaxation technique treatment, most respondents experienced moderate pain (scale 4-6) as many as 28 respondents (80%). The results of data analysis obtained the Asymp.significancy value = 0.000 (ρ<0.05). The conclusion is that there is an effect of providing deep breathing relaxation techniques on reducing labor pain in the first active phase. It is hoped that deep breathing relaxation techniques can be applied in the management of labor care as an alternative to reduce labor pain for mothers giving birth in the first active phase

Pain is one of the main complaints experienced by postoperative patients, including those undergoing laminectomy, which can interfere with comfort, hinder mobility, and slow the healing process. Non-pharmacological nursing interventions such as relaxation techniques have become important alternatives for reducing pain holistically. This study aims to evaluate the effectiveness of the finger-holding relaxation technique in reducing pain in postoperative laminectomy patients. The study used a descriptive case study design involving a patient named Mrs. S in the Amarilis Ward of Prof. Dr. Margono Soekarjo Regional Hospital, Purwokerto. The intervention was carried out for three consecutive days, twice a day, with each session lasting 15 minutes. The results showed a marked decrease in pain score from a scale of 7 (severe pain) on the first day to 1 (mild pain) on the fourth day, accompanied by gradual improvement in physical mobility, absence of surgical wound infection, and better discharge readiness. This technique also had a positive impact on the patient’s emotional comfort. Therefore, the finger-holding relaxation technique is proven to be a simple yet effective intervention in supporting the holistic recovery of postoperative laminectomy patients.

Back discomfort is a common musculoskeletal complaint among pregnant women, particularly in the third trimester, caused by biomechanical and physiological changes during pregnancy. This condition can interfere with daily activities, reduce sleep quality, and decrease overall comfort. Pharmacological treatments during pregnancy are limited due to safety concerns, making non-pharmacological therapies essential in primary healthcare. One alternative is the use of warm ginger compresses, which combine the benefits of heat therapy with the anti-inflammatory properties of ginger. This study aimed to examine the effect of warm ginger compresses on reducing back pain intensity in third-trimester pregnant women at the Jailolo Community Health Centre. The research used a pre-experimental one-group pretest–posttest design. The sample consisted of 16 pregnant women selected through purposive sampling. Pain intensity was measured using the Numeric Rating Scale (NRS) before and after the intervention. The treatment involved applying warm ginger compresses to the lower back following a standardized procedure. Data analysis was conducted using univariate and bivariate methods with the Wilcoxon signed-rank test. The results showed a significant reduction in back pain intensity after the intervention (p < 0.05). These findings indicate that warm ginger compresses are an effective, safe, and simple non-pharmacological method for reducing back pain in third-trimester pregnant women.

Post-Cesarean Section (C-Section) patients commonly experience pain caused by surgical incisions in the abdominal area. Unmanaged pain may hinder mobility, interfere with breastfeeding, reduce comfort, and negatively affect maternal psychological well-being. Non-pharmacological pain management is considered an alternative to reduce dependence on analgesics. Foot massage has been proven to improve blood circulation, stimulate endorphin release, and reduce pain intensity, while Qur’anic recitation therapy (murottal) provides psychological and spiritual relaxation that helps decrease pain perception. This study aims to examine the effect of combining foot massage and murottal therapy on pain levels in post-C-section patients at Wijaya Kusuma ward, Limpung General Hospital. The benefit of this study is expected to provide a reference for nursing practice, particularly in implementing holistic non-pharmacological interventions to enhance patient comfort. This research employed a case study design with a nursing care approach involving four post-C-section patients. Interventions included a scheduled combination of foot massage and murottal therapy. Pain levels were measured using the Numeric Rating Scale (NRS). Data were analyzed descriptively by comparing pain levels before and after intervention. The results showed a reduction in pain intensity from moderate to mild after the combination intervention. Patients also reported increased comfort, improved rest, and reduced anxiety. In conclusion, the combination of foot massage and murottal therapy effectively reduces pain in post-C-section patients. This intervention can be recommended as a non-pharmacological method in nursing care for post-C-section patients.

Low Back Pain (LBP) is often caused by spondylolisthesis, which causes pain, limited mobility, and disability. Conservative physiotherapy is the primary option to reduce symptoms and improve function. This study aims to evaluate the effectiveness of multimodal physiotherapy interventions in patients with LBP and spondylolisthesis. A case report study was conducted on a 59-year-old female patient diagnosed with LBP and spondylolisthesis. The patient underwent three physiotherapy intervention sessions: Infrared (IR), Short-Wave Diathermy (SWD), Transcutaneous Electrical Nerve Stimulation (TENS), William Flexion Exercise, Core Stability, and Strengthening. Evaluation was performed using the Numeric Rating Scale (NRS) for pain, a goniometer for joint range of motion (LGS), Manual Muscle Testing (MMT) for muscle strength, and the Oswestry Disability Index (ODI) for function. The results of the therapy showed a significant reduction in pain, namely silent pain from a score of 5 to 1 and pain on movement from a score of 6 to 3. Lumbar ROM increased with flexion from 70 degrees to 85 degrees. Lumbar muscle strength also improved, flexors from a score of 4 to 5 and extensors from a score of 3 to 5. ODI decreased from 55.5% (severe disability category) to 12% (minimal disability category). Multimodal physiotherapy interventions have been proven effective in reducing pain, improving LGS, muscle strength, and function in patients with LBP et causa spondylolisthesis.

Back pain is a common complaint among pregnant women, especially in the third trimester, caused by hormonal changes, uterine enlargement, and poor postural balance. If untreated, this pain can disrupt sleep quality and daily activities. The pelvic tilt technique, a non-pharmacological intervention, strengthens abdominal and pelvic muscles, maintains posture, and relieves back pain. This study examined the effect of the pelvic tilt technique on back pain intensity in third-trimester pregnant women at Karangdoro Public Health Center. The study used a quasi-experimental design with a one-group pretest–posttest approach. The population consisted of all third-trimester pregnant women with physiological back pain (without comorbid conditions or a history of premature rupture of membranes). Using a total sampling technique, 34 respondents were included. The intervention was conducted for seven consecutive days. Data collection employed observation sheets and the Numeric Rating Scale (NRS). Data analysis used the Wilcoxon test because the normality test yielded p < 0.05. Statistical results showed p = 0.000 (< 0.05), indicating that the pelvic tilt technique significantly reduced back pain intensity. These findings suggest that pelvic tilt exercises can serve as a safe, simple, and effective non-pharmacological alternative therapy to alleviate bapain in third-trimester pregnant women.

Abdominal pain is one of the main complaints frequently encountered in patients in emergency departments and inpatient wards. This condition may be caused by various factors, ranging from gastrointestinal disorders and inflammation to reproductive system problems. Poorly managed pain can affect the patient’s quality of life, reduce daily activities, and increase anxiety. This case study aims to describe nursing care for Mrs. U, who presented with abdominal pain at dr. Soeselo Hospital, Tegal Regency. The research method applied was a case study with a nursing process approach, including assessment, diagnosis, intervention, implementation, and evaluation. The assessment revealed that the patient complained of lower abdominal pain with a pain scale of 5 (moderate), accompanied by nausea, weakness, and intermittent fever. The primary nursing diagnosis established was acute pain related to physiological injury agents. Interventions included pain management education, relaxation techniques, application of warm compresses, and collaboration in administering analgesics. The evaluation showed a decrease in pain intensity from a scale of 5 to 3, with the patient appearing calmer and showing improved sleep quality. This study emphasizes the crucial role of nurses in providing comprehensive care to reduce abdominal pain through both independent and the collaborative interventions with the medical team.

Background: Knee osteoarthritis is one of the most common degenerative conditions in older adults, often causing pain and limited range of motion (ROM), which negatively affects quality of life. Physiotherapy management plays an important role in reducing pain, improving flexibility, and maintaining joint function. Objective: This study aims to evaluate the effectiveness of physiotherapy interventions in reducing pain and improving ROM in elderly patients with knee osteoarthritis. Method: A case study was conducted on a 63-year-old patient at Dr. Soedjono Level II Hospital, Magelang, who underwent three therapy sessions consisting of Infrared (IR), Transcutaneous Electrical Nerve Stimulation (TENS), Proprioceptive Neuromuscular Facilitation (PNF) with the hold-relax technique, and static cycling. Assessments were carried out using the Numeric Rating Scale (NRS), Likert Gait Scale (LGS), and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results: The findings showed a significant reduction in pain on palpation (from 4/10 to 1/10), improvement in knee flexion ROM (from 110° to 135°), and functional enhancement indicated by a decrease in WOMAC scores from 39.58% to 27.08%. Conclusion: These results suggest that structured physiotherapy interventions provide therapeutic benefits in reducing pain, improving joint flexibility, and enhancing functional ability in elderly patients with knee osteoarthritis.

Introduction: Back pain during pregnancy is a problem that is often experienced by pregnant women and is complex because it involves not only physical changes, but also psychological aspects. Changes in body biomechanics, weight gain, and shifting of the center of gravity due to uterine enlargement are the main factors that trigger pain complaints, especially in the lower back area. This condition can have a negative impact on the quality of life of pregnant women, interfere with daily activities, and even worsen emotional states due to the emergence of anxiety, fear, and stress if not managed properly. Treatment of back pain in pregnant women can be done through safe non-pharmacological methods, one of which is prenatal yoga. Yoga practice for pregnant women has been proven to provide benefits in the form of relaxation, posture improvement, and increased muscle elasticity. One of the effective movements is the Angry Cat Pose because it is able to stretch the back muscles, improve blood circulation, and reduce pressure on the lower spine. Objective: This study aims to analyze the effect  of Angry Cat Pose  exercise on the intensity of back pain in pregnant women in the third trimester. Methods: This study used a quasi-experimental design with a one group pretest-posttest design. The study sample consisted of 31 pregnant women in the third trimester with complaints of back pain who visited the Gunungpati Health Center. The research instrument was in the form of a questionnaire, while the data analysis was carried out using the Wilcoxon test with a significance level of <0.05. Results: The results showed a significant effect of the Angry Cat Pose  exercise on the reduction of back pain in pregnant women in the third trimester with p=0.000. After the intervention, the majority of respondents experienced a decrease in pain to the mild category on a scale of 1–3. Conclusion: The Angry Cat Pose  exercise has been shown to be effective in reducing back pain in third trimester pregnant women, so it can be recommended as a safe, simple, and routine nonpharmacological intervention under the supervision of health workers.

Pain is one of the main problems that cancer patients who undergo chemotherapy often experience, both as a direct result of the development of the disease and as a side effect of the therapy undergone. Pain that is not handled properly can decrease the quality of life, interfere with daily activities, and negatively impact the patient's psychological state. Therefore, non-pharmacological interventions are important as a companion effort to medical treatment. This study aims to analyze the effect of the combination of Benson relaxation technique and Quranic Healing therapy on the pain level of cancer patients undergoing chemotherapy at the Sultan Agung Islamic Hospital Semarang. The research uses a quasi experiment design with a nonequivalent control group design approach. The sample size was 36 respondents, divided into intervention groups and control groups, each consisting of 18 respondents. Pain levels were measured with the Numeric Rating Scale (NRS) instrument before and after the intervention. Data analysis was performed using the Wilcoxon test for differences within groups and the Mann–Whitney test for differences between groups. The results showed a significant decrease in pain levels in the intervention group (p = 0.000) compared to the control group (p = 0.046), with a significant difference between the two groups after the intervention (p = 0.001). In conclusion, the combination of Benson relaxation techniques and Quranic Healing has been shown to be effective in reducing pain in cancer patients undergoing chemotherapy. These interventions can be recommended as an alternative to non-pharmacological nursing measures to improve the comfort and quality of life of cancer patients.