Publication Search

Circulating drugs without a distribution permit is a criminal act, where the drugs being distributed are not necessarily relevant to their composition and manufacture. This means that the safety, efficacy and benefits of drugs being traded are not guaranteed. Then the perpetrators of distributing drugs without a distribution permit will be punished and subject to criminal penalties. In this case Law no. 17 of 2023 concerning Health regulates criminal provisions for perpetrators of distributing drugs without a distribution permit with a prison sentence of 12 years and a fine of five billion rupiah, but the criminal sanctions imposed by the judge in decision case number 111/pid.B/2013/PN/ are reduced. Mtr does not provide a deterrent effect for perpetrators. The problems in this research are: first, what is the responsibility for perpetrators of criminal acts of distributing drugs without a distribution permit? Second, what are the judge's considerations in handing down a decision regarding the distribution of drugs without a distribution permit in case number 111/pid.B/2013/PN/Mtr?The results of this research are to show that the form of responsibility of the defendant is in accordance with the elements of responsibility, because the actions carried out by the defendant contained an element of intentional error and the judge sentenced the defendant to 10 months' imprisonment, which according to the author was not appropriate because the sentence This will not have a deterrent effect on the perpetrator.

Dismenore adalah nyeri pada abdomen yang dirasakan sesaat sebelum atau pada saat menstruasi dan mengganggu aktifitas sehari-hari, bahkan sering kali mengharuskan penderita beristirahat dan meninggalkan aktifitasnya selama berjam-jam akibat nyeri haid. Latihan fisik dan olahraga akan mengakibatkan pelepasan endoprin, suatu substansi yang diproduksi oleh otak yang ambang rasa nyeri (Prawirohardjo, 2008). Glycine Max L atau sering disebut dengan kedelai merupakan salah satu tanaman jenis kacang-kacangan yang dapat membantu menurunkan nyeri haid. Mengkonsumsi makanan yang terbuat dari kacang kedelai dapat membantu merangsang produksi hormon estrogen saat menstruasi dan mengurangi peradangan serta nyeri menstruasi. Studi Pendahuluan di Trenclass SMA Muhammadiyah Wonosobo dengan wawancara secara langsung kepada 10 santriwati dengan hasil sebagian besar mengalami dismenore dengan skala nyeri ringan 4 snatriwati, skala nyeri sedang 6 santriwati. Ketika sedang dismenore dari 10 orang yang diwawancarai secara langsung mengalami gejala seperti mual, hilang nafsu makan, pusing, pinggang terasa sakit dan ada beberapa santriwati yang sampai tidak bisa menjalani aktivitas sehari-harinya. Penanganan yang biasa diberikan adalah 4 santriwati dengan kompres air hangat dan 6 santriwati lainnya menggunakan obat Pereda nyeri dengan jenis ibuprofen. 

Medicinal plants are plants that are known to contain beneficial compounds that can prevent, alleviate, or cure diseases. Knowledge about medicinal plants has different characteristics depending on the region. This study aims to document the knowledge of residents of the Legok Hayam Cultural Village, Girimekar Village, Bandung Regency about traditional medicinal plants. The ethnobotanical research method was conducted from September 2024 using semi-structured interviews and observations with measurement parameters of Species Use Value (SUV), Family Use Value (FUV), and Fidelity Level (FL). The research sample used a random sampling technique with a total of 25 respondents. The results identified 25 medicinal plants belonging to 15 families, traditional medicinal plants are often obtained by planting in the yard. The most frequently used medicinal plants are ginger, turmeric, binahong and kencur based on their highest utility value. The Zingiberaceae family has the largest contribution to use. In addition, binahong, kencur, katuk, and ginger plants are widely used to treat certain diseases.

Good pharmaceutical procurement management can prevent stock shortages, reduce costs, and improve healthcare service quality. However, issues such as medication shortages, delayed procurement, and discrepancies between demand and supply are still common. This literature review aims to analyze pharmaceutical procurement management in hospital pharmacy units. The literature search yielded 10 relevant articles on pharmaceutical procurement management in hospital pharmacy units. The databases used were Google Scholar, ScienceDirect, and Semantic Scholar. The keywords used were management, pharmaceutical procurement, and hospital. The search results underwent a screening process using the PICO elements and the CRAAP method. The findings indicate that pharmaceutical management in various hospitals has shown progress, but still faces challenges such as inaccurate data collection, delayed drug supply, and storage facilities that do not meet standards. Other obstacles include limited funds, inability to pay on time, and a lack of integrated information systems. However, some aspects are well-managed, such as the use of e-purchasing and proper drug storage categorization.

This study discusses the use of beluntas plants (Pluchea indica) as medicinal plants in Bojong Salam Village, Banyuresmi District, Garut. Ethnobotany investigates the interaction between people and plants, particularly in the context of traditional medicine. The people of Bojong Salam Village have long used beluntas plants as medicine to treat body odor, bad breath, back pain, and vaginal discharge. This study involved interviews with 30 respondents using a purposive sampling method. In data analysis, quantitative and qualitative approaches were used, including calculating the Use Value (UV) and Fidelity Level Index (FIC). The results showed that beluntas leaves had the highest UV value of around 0.5 and FIC of around 50% as a medicine for vaginal discharge, followed by other benefits as a medicine to eliminate body odor, bad breath and back pain. The results showed that beluntas is an important plant in traditional medicine used by the people of Bojong Salam Village.

Family support is one of the main factors in the process of medication support adherence of schizophrenic patients. So the patient's health can be maintained longer. This study aims to analyze the correlation between family support and medication adherence of schizophrenic patients in the Polyclinic of Aceh Mental Hospital. A quantitative survey with an analytical design using a cross-sectional approach is employed in this research. The data was gathered from 83 respondents chosen using a purposive sampling technique. The data collection was conducted from July 22nd - 30th, 2024. A family support instrument and The Morisky Medication Adherence Scale (MMAS-8) were used for the data collection technique. Univariate and bivariate analyses are used to analyze the data. The result shows that 45 respondents (54, 2%) had good family support, and 58 respondents (69, 9%) had good medication adherence. These findings indicate a correlation between family support and medication adherence of schizophrenic patients in the Polyclinic of Aceh Mental Hospital with a ρ-value of 0,000. This study recommends that families with schizophrenia maintain and or increase supervision by providing support for medication adherence.

Pada saat ini jamu yang awalnya hanya sebagai obat tadisional kini mulai berubah menjadi sebuah usaha industri yang terus berkembang. Industri jamu bisa dikembangkan di Indonesia karena  salah satunya didukung dengan adanya fakta bahwa banyaknya tanaman obat yang ada di berbagai daerah di Indonesia kurang lebih sebanyak 30.000 spesies dari jumlah total keseluruhan 40.000 tanaman obat yang ada di dunia. Pulau Madura menjadi salah satu pulau yang cukup terkenal dengan jamu tradisionalnya. Salah satu daerah penghasil jamu di pulau Madura yaitu ada di Kabupaten Pamekasan. Berdasarkan studi literatur yang dilakukan oleh penulis diketahui bahwa saat ini terdapat penurunan dalam sektor industri jamu yang salah satunya disebabkan oleh kurangnya minat dan motivasi masyarakat untuk meneruskan usaha jamu tradisional, adanya peratuan menteri kesehatan (PERMENKES) nomor 06 tahun 2012, kebanyakan pemilik usaha jamu pada saat ini sudah berusia tua dan tidak paham mengenai perkembangan digitalisasi yang bisa digunakan untuk meningkatkan produktivitas perusahaan. Oleh karena itu penelitian ini bertujuan untuk mengetahui pengaruh perencanaan SDM dan motivasi kerja terhadap kinerja pembuat jamu pada industri jamu tradisional di Kabupaten Pamekasan. Sehingga diharapkan nantinya penelitian ini akan dapat membantu industri jamu yang ada di Kabupaten Pamekasan dapat meningkatkan kinerjanya dan mempertahankan eksistensinya.

The programming language used in this web development is PHP using the Laravel framework and the RDBMS used is MySQL. The system development model used is the SDLC waterfall model so that the work is gradual and more structured. This research resulted in web-based drug management at the Jambi City Pharmaceutical Installation UPTD being able to solve the problem of recording incoming drugs from Pharmaceutical Wholesalers, Submission of LPLPO files by Puskesmas as official proof of drug needs at the Puskesmas, outgoing drugs during drug distribution activities to Puskesmas, data on Pharmaceutical Wholesalers who partner as drug suppliers at the Jambi City. Health Office Pharmaceutical Installation UPTD Warehouse, data on health centers in Jambi City along with officers who will come during distribution and drug data that will be returned to the Pharmaceutical Wholesaler responsible for the product.

Dengue fever is an infectious disease caused by the Dengue virus which is transmitted through mosquito bites. This disease causes symptoms of high fever, headache, and bone and muscle pain. If not treated properly, dengue fever is life threatening. The main symptom of dengue fever is a sudden increase in body temperature. Fever in dengue hemorrhagic fever generally lasts for 3 days. Fever can reach temperatures of 39-40°C and is difficult to reduce even if the patient has taken fever-reducing medication.Medicinal plants contain active compounds which can act as anti-bacterial, anti-viral, anti-plasmedial, anti-oxidant, anti-inflammatory, anti-allergic, anti-cancer, immunomodulator (improving the body's immune system) and so on. Several types of medicinal plants that have activity as immunomodulators include: echinacea, noni, ginger, meniran, and bitter (Wuryaningsih & Suranto, 2012).    Currently, there are a lot of foods and drinks offered as supplement products that can improve body health, one of which is herbal drinks, which are drinks containing compounds that can have a positive effect on body health. One example of herbal drinks that can be found is herbal drinks from ginger, turmeric, etc. To overcome this problem, it is necessary to educate the public about types of medicinal plants, their properties, and how to process them appropriately based on an evidence-based scientific approach by adapting methods to these conditions.

Cancer therapy has long faced the challenge of balancing treatment effectiveness with minimizing damage to healthy tissues. Conventional therapies such as chemotherapy and radiotherapy, although widely used, often lead to significant side effects due to their non-specific nature. This study aims to analyze the effectiveness of microscopic robots in delivering drugs precisely to cancer cells, thereby reducing collateral damage. The research employed simulations and in vitro preclinical tests using cancer cell cultures to evaluate both targeting accuracy and safety. Findings indicate that microscopic robots achieved 93% effectiveness in targeting cancer cells while limiting damage to healthy cells to only 10%. Compared to chemotherapy, radiotherapy, chemoradiotherapy, and nanoparticle-based drug delivery systems, microscopic robots demonstrated superior precision and efficiency. These results suggest that microscopic robots hold great potential as a breakthrough technology in precision cancer therapy, offering new possibilities for safer and more effective treatments. However, further research is required to address long-term biocompatibility, control mechanisms within the human body, and clinical validation. This study highlights the transformative potential of integrating microscopic robots into future cancer treatment strategies, contributing to the advancement of personalized medicine.

Community service activity on "Getting to Know Medicine More Closely with the Children of the Manarul Mabrur Orphanage" located on Pudak Umbrella, Banyumanik, Semarang, Central Java. The aim of this community service activity is to spread knowledge and be able to improve the quality of life and daily behavior to the wider community, including the children of the orphanage. This education is provided using education methods to the children of the orphanage. The first is education about what forms of drug preparation there are and the second is education about how many categories of drugs there are and the third is education about the use/method of consuming drugs and storing drugs, then the next activity continues with questions and answers and a pretest was held before the presentation of the material and a posttest after the presentation of the material for all children at the orphanage.  Before the education, the level of knowledge was quite good, but after the presentation of the educational material, the level of knowledge was very good. In this case, students are able to understand the material that has been presented and increase the knowledge of the children of the orphanage.

TB is one of the 10 causes of death and the primary cause of infectious agents in the world. The prevalence of tuberculosis patients in 2020 amounted to 929 patients. Some of the influencing factors are behavioral factors, namely knowledge, attitude and behavior in the implementation of routine medication compliance. The method used was observational descriptive with 30 participants who were residents of Sampali Village, Percut Sei Tuan District. The PkM team provided the material in question: 1) Definition of tuberculosis disease, 2) Causes of tuberculosis disease, 3) Signs and symptoms of tuberculosis disease, 4) Complications of tuberculosis disease, and 5) Prevention of tuberculosis disease. After the implementation of the activity: 1) The majority of the understanding of tuberculosis (TB) is good as many as 25 people, 2) The causes of tuberculosis (TB) are mostly good as many as 27 people, 3) The signs and symptoms of tuberculosis (TB) are mostly good as many as 26 people, 4) The majority of tuberculosis (TB) complications are good as many as 27 people, and 5) Prevention of correct transmission of tuberculosis (TB) all participants have been able to as many as 27 people. The increase in knowledge and skills of participants is because the community has a great desire to treat and prevent dengue fever in family members at home.

Peptic ulcer is a condition where there is a wound or ulcer on the inner lining of the stomach. Gastroesophageal Reflux Disease (GERD) occurs when stomach contents flow back into the esophagus and can damage the mucosal lining of the esophagus. Extension activities carried out at SMA Santo Lukas 1, obtained pre-test results for correct answers of 82.08% and for wrong answers of 17.92%, while the post-test results showed a significant increase after the provision of material, namely for correct answers of 93.33% and wrong answers of 6.67%. This shows that most students understand the information delivered through counseling activities regarding GERD and peptic ulcers.

Objective: This study aims to determine the relationship of stress and physical activity with the occurrence of fluor albus (vaginal discharge) in young women in vocational high schools.Methods: This study uses a cross-correlation correlation design. The population of this research is vocational high school students on January 17, 2020involving a sample of 76 respondents. Data obtained by structured interviews, stress research instruments using the Depression Anxiety Stress Scale (DASS 21)questionnaire, physical activity questionnaire and vaginal discharge questionnaire. Data analysis using chi square test.Results:Based on the results of the study found 40respondents (52.6%) experienced vaginal discharge,and 36 respondents (47.4%) did not experience vaginal discharge. After doing the chi square test, the p value stress is 0.001 <0.005, and the physical activity with the value of p value is 0.001 <0.005,which means that stress and physical activity have a significant relationship.Conclusion: From this study there is a significant relationship between stress and physical activity with the incidence of fluor albus in girls in vocational school.

Sijukkot plants grow widely in the highlands of Lake Toba, the largest volcanic lake in the world. This plant, with the Latin name Lactuca indica L., grows abundantly in Dairi, Pakpak Bharat, Samosir and Humbang Hasundutan districts. Sijukkot has been proven to have made people in the Lake Toba area less susceptible to disease. Sijukkot contains many high chemical compounds in the roots, stems and leaves. For example glycosides, cardeolin, polyphenols, saponins, cardenolin, polyphenols, flavonoids and tannins. ( Molecular Docking ) is one of the simplest and most frequently used structure-activity based virtual methods. The purpose of this journal review is to determine the secondary metabolite compounds contained in the medicinal plant sijukkot to be developed as a fever reducer The research method used is a library study and literature review with the keywords molecular docking of secondary metabolite compounds of sijukkot as a medicinal plant to reduce fever, in the period 2020-2022. The results obtained were 5 secondary metabolite compounds which have potential as fever reducers and antioxidants. The conclusion is that ethanol extract and sijukkot leaves have high levels of phytochemicals which are good as formulations for fever medicine, antioxidant, antibacterial and can reduce sugar levels

Health is a state of health, both physically, mentally, spiritually and socially that allows everyone to live productively socially and economically. Health is based on legal provisions, including health law. The development of criminal acts in the field of health sciences One of the crimes in health law that is rampant is the crime in the field of pharmacy, one of which is circulating pharmaceutical preparations of drugs without a distribution permit. Drugs without a distribution permit cannot be freely traded to the public. This is not without reason, unlicensed drugs must be consumed in the right dosage so as not to endanger the health of the public or the people who consume the drug. This research is a normative juridical research using secondary data through literature studies, namely by using research on various sources of books, laws and regulations related to the crime of producing and distributing pharmaceutical preparations without a distribution permit. From the research conducted, it can be concluded that the application of criminal sanctions against criminal offenders who circulate pharmaceutical preparations without a distribution permit is contained in several laws and regulations, namely, Law No. 17 of 2023 concerning Health and Law No. 36 of 2009 concerning Health as a means of crime prevention. The implementation of this law is expected to ensnare the perpetrators of the crime of distributing pharmaceutical preparations without a distribution permit.

The storage of medicines and medical consumables is a management process to ensure that the received medicines remain safe, free from physical and chemical damage, and maintain their quality. Medication damage not only negatively impacts patients but also affects the efficiency of healthcare facilities. Healthcare facilities serve as venues for implementing various health efforts, including promotive, preventive, curative, and rehabilitative measures, conducted by the government, local authorities, or the community. As primary healthcare facilities, Puskesmas prioritize promotive and preventive efforts to improve the health status of the communities in their service areas. This study aims to analyze the compliance levels of medicine storage, arrangement in storage rooms, and warehouse requirements at Puskesmas Siring Betik and Puskesmas Wonosobo, Wonosobo District, Tanggamus Regency, in 2024. The research employed a descriptive quantitative design with a saturated sampling technique, using observation sheets guided by the standards outlined in Permenkes RI No. 74 of 2016 regarding Pharmaceutical Service Standards at Puskesmas and the 2010 Directorate General of Pharmaceutical and Medical Devices Training Materials on Pharmaceutical Management. The results showed that medicine storage compliance at both Puskesmas Siring Betik and Wonosobo reached 100%. In terms of medicine arrangement, Puskesmas Siring Betik achieved a compliance rate of 87%, while Puskesmas Wonosobo reached 100%. Regarding warehouse requirements, the compliance level at both Puskesmas was 85%. Overall, the compliance levels were 81.25% for Puskesmas Siring Betik and 84% for Puskesmas Wonosobo..

Access to mental healthcare, especially psychopharmacological treatment, for people with psychosocial disabilities (ODDP) remains a significant challenge in Indonesia. Discrepancies between regulations and their implementation, coupled with limited availability of psychiatric medications, pose major obstacles. This research analyzes the collaborative efforts of the Mental Health Association (PJS) and its strategic partners in advocating for increased access to medication for ODDP. The research focuses on the stages of advocacy, the roles of each partner, the collaboration process, and the outcomes of these advocacy efforts. Employing a qualitative approach, this research involved in-depth interviews with PJS officials to explore the roles of partner institutions in advocacy. The findings reveal that PJS has systematically engaged in advocacy, collaborating with various strategic partners such as BPJS Watch, WHO Indonesia, and PDSKJI. This collaborative effort has proven effective in identifying issues, formulating solutions, and driving policy changes. However, challenges such as limited resources and the complexity of the issues persist. The research concludes that collaboration among partner institutions is key to improving access to medication, particularly psychiatric medications, for ODDP. Sustained and measurable advocacy is necessary to ensure that ODDP can obtain equitable and accessible quality mental health services.

This study aims to find out and analyze the legal protection for consumers against the circulation of children's syrup drugs that cause acute kidney failure in BPOM Kupang City. This study is an empirical legal research that is analyzed in a qualitative descriptive manner using primary data and secondary data obtained from interviews and literature studies. The results of this study show (1) legal protection for consumers over the circulation of children's syrup drugs, which causes acute kidney failure which is known that consumer protection in Indonesia currently according to researchers is still not running well. (2) the responsibility of the Food and Drug Supervisory Agency in providing protection for children's syrup drugs that cause acute kidney failure which is known to indicate that BPOM's task of supervising drugs is not effective because there are still many cases of dangerous circulation of children's syrup drugs.

Acute Respiratory Infection (ARI) is a significant public health issue, particularly in areas with suboptimal environmental conditions. Community Health Centers (Puskesmas), as the primary healthcare providers, play a crucial role in managing ARI cases. This study aims to analyze the prescribing patterns of medications for ARI patients at Pekanbaru Community Health Center to evaluate whether the prescribed treatments adhere to existing guidelines and to provide recommendations. The sample for this study comprises ARI patients who sought treatment at Pekanbaru Community Health Centers in March 2024. Secondary data from the monthly report of Pekanbaru Community Health Centers in March 2024 was used as the research instrument. The collected data was analyzed by calculating the percentage of medication usage. Based on the findings from Pekanbaru Community Health Centers, the following conclusions were drawn: Most patients consuming ARI medications were female, with 80 respondents, compared to 70 males. The age group with the highest number of ARI medication consumers was [missing data]. Paracetamol 500mg was the most commonly prescribed medication at the health center."