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The development of modern biotechnology has brought fundamental changes to the life sciences through the application of molecular biology, genetic engineering, and bioinformatics techniques. This article aims to examine the transformation of life sciences through modern biotechnology approaches and its impact on health, agriculture, the environment, and industry. The method used is a descriptive-analytical literature review based on international journal sources and relevant scientific publications. The results of the study indicate that technologies such as CRISPR-Cas9 enable precise gene editing for genetic disease therapy, while the mRNA vaccine platforms developed by Pfizer and Moderna demonstrate the acceleration of biomedical innovation in response to the global pandemic. In the agricultural sector, genetic engineering increases crop productivity and resilience, while in the environmental sector, biotechnology supports environmentally friendly bioremediation processes. However, ethical and regulatory challenges remain important concerns in its implementation. In conclusion, modern biotechnology plays a key role as a catalyst for sustainable, innovation-driven transformation in the life sciences.

The danger of cadmium contamination in water sources remains a crucial environmental issue due to its persistent nature and high toxicity level, which poses serious risks to human health and ecosystems. Cadmium is a non-biodegradable heavy metal that can accumulate in living organisms over time. The presence of these toxic Cd²⁺ ions is known to trigger damage to vital organs such as the liver and kidneys; therefore, reducing their concentration in aquatic environments is of paramount importance for environmental protection and public health safety. Among various treatment methods, adsorption is considered one of the most effective and economical techniques for removing heavy metal ions from contaminated water. In this study, the capability of mesoporous silica MCM-48-NH₂ as an adsorbent for Cd²⁺ ions was systematically evaluated. The adsorption performance was examined by investigating several important parameters, including contact time, solution acidity level (pH), and initial Cd²⁺ concentration. Furthermore, the adsorption mechanism and interaction between Cd²⁺ ions and the adsorbent surface were analyzed using Langmuir and Freundlich isotherm models. The results demonstrate that the adsorption process of Cd²⁺ ions onto MCM-48-NH₂ tends to follow the Langmuir isotherm model, indicating monolayer adsorption behavior, with a maximum adsorption capacity of 0.66 mmol g⁻¹.

Lemongrass (Cymbopogon citratus) is a plant known to contain various bioactive compounds with potential antioxidant properties as well as xanthine oxidase (XO) inhibitory activity. This study aimed to evaluate the phytochemical content, antioxidant activity, and XO inhibitory potential of ethanol extracts from the leaves, stems, and their combination. Phytochemical screening revealed that all extracts contained alkaloids, flavonoids, and terpenoids, while phenolic compounds were detected only in the leaf extract and the combined leaf–stem extract. Antioxidant activity assays demonstrated that all extracts exhibited very strong antioxidant activity, with IC₅₀ values below 50 ppm, indicating a significant potential to scavenge free radicals. In the XO inhibition assay at a concentration of 200 ppm, the ethanol extract of lemongrass stems showed the highest inhibitory activity at 81.37%, followed by the leaf extract at 48.08% and the combined leaf–stem extract at 33.65%. Overall, these findings suggest that the ethanol extract of lemongrass stems is the most promising natural source of antioxidants and has the greatest ability to inhibit xanthine oxidase activity, indicating its potential development as a functional ingredient for health applications.

The development of lanthanum-doped barium hexaferrite materials has attracted considerable attention in the field of functional materials, particularly as electromagnetic wave absorbers. This literature review aims to analyze advances in synthesis methods, structural characteristics, magnetic properties, and electromagnetic absorption performance of lanthanum-doped barium hexaferrite reported in various studies. Synthesis techniques such as sol–gel, coprecipitation, solid-state reaction, and hydrothermal methods are compared to evaluate their effects on crystallite size, morphology, and phase purity. Lanthanum doping is known to modify lattice parameters, reduce coercivity, and enhance complex permittivity and permeability, which play crucial roles in absorption mechanisms. Furthermore, variations in dopant concentration significantly influence reflection loss values and effective absorption bandwidth. The reviewed literature indicates that optimization of composition and synthesis routes can produce materials with high absorption capability, good stability, and strong potential for application in electromagnetic interference mitigation devices. This review is expected to serve as a conceptual reference for future development of lanthanum-doped barium hexaferrite–based electromagnetic wave absorbing materials. The comparative approach also highlights research challenges, industrial application opportunities, and future research directions relevant to the evolving demands of modern communication and defense technologies at both national and global levels.

This study comprehensively evaluates the quality of biomass briquettes produced from blends of coconut shell charcoal and sengon sawdust, using both carbonized and non-carbonized materials. Composite briquettes were fabricated with varying compositions and characterized through proximate analysis, calorific value, density, and burning rate measurements to determine their suitability as solid fuel. The results indicate that adding non-carbonized sawdust increases volatile matter content and burning rate but reduces the calorific value of the briquettes. In contrast, incorporating up to 10% carbonized sawdust significantly improves the calorific value to 6119.2 cal/g, approaching that of pure coconut shell charcoal (6352.2 cal/g), while maintaining a relatively high burning rate. Briquettes containing carbonized sawdust also exhibit low ash content, below 3%, and moisture content under 8%, meeting standard solid fuel quality requirements. These findings demonstrate that a strategic combination of carbonized and non-carbonized materials can produce hybrid biomass briquettes with optimized thermal performance, providing a promising, sustainable, and environmentally friendly alternative fuel for domestic and industrial applications.

The discharge of surfactant-laden wastewater from the rapidly expanding laundry industry poses significant environmental risks, especially in densely populated urban areas. While constructed wetlands (CWs) and Eco-Enzyme technology have shown promise for surfactant remediation, their standalone application requires long hydraulic retention times (HRTs), limiting practical implementation. This study evaluated the efficacy of a novel integrated system combining a subsurface constructed wetland (SSFCW) with fruit peel-derived Eco-Enzyme to treat synthetic laundry wastewater. Over a 6-day treatment period, the combined system achieved a remarkable surfactant removal efficiency of 99.63%, reducing the concentration from 225 mg/L to 0.835 mg/L—well below the regulatory threshold of 3 mg/L. The synergistic degradation mechanism involves enzymatic hydrolysis via Eco-Enzyme lipase and protease activity, complemented by microbial mineralization in the wetland rhizosphere. This system maintains optimal environmental conditions, with a stable pH of 6.85-7.32 and a temperature of 30.9-35.2°C, supporting robust biological activity. These findings demonstrate that the integrated Eco-Enzyme/SSFCW system overcomes the limitations of conventional HRT approaches, offering a highly efficient, sustainable, and practical decentralized wastewater treatment solution for the laundry industry.  

This study discusses the implementation of the Self-Directed Learning Programme by integrating Learning Outcomes (CP), Learning Objectives (TP), and Learning Objective Processes (ATP) to enhance teaching quality and teacher professionalism. Using a library research method, this study analyses relevant scientific literature to understand the relationship between the integration of the three components of the education programme and classroom teaching practices. The research findings indicate that teachers still encounter challenges in understanding and integrating CP, TP, and ATP, particularly in planning, implementing teaching strategies, and conducting authentic assessments. However, when this integration is well executed, the teaching process becomes more purposeful, flexible and responsive to students' needs. Furthermore, integrating CP–TP–ATP has been shown to strengthen teachers' professionalism by enhancing their understanding of the curriculum, their ability to design learning activities, and their capacity to conduct competency-based assessment. This study confirms that the successful implementation of the Free Education Programme depends heavily on teachers' ability to understand the curriculum's structure and to integrate these three components consistently. Therefore, training, supporting, and developing teachers' competencies is an important requirement for the effective and sustainable implementation of the Liberal Education Programme.

This research extends the previous work of Tsaqila, Winiarti, and Widaningrum (2024), who applied the Complex Proportional Assessment (COPRAS) method within a decision support system for supermarket branch location selection. Unlike the prior study, which focused on Ponorogo through a web-based framework, this study expands the implementation of COPRAS to the Medan Area, Medan Kota, Medan Polonia, dan Medan Maimun districts, adapting it to local urban, social, and economic characteristics. The main objective is to identify the most strategic site for a new supermarket by analyzing multiple criteria, including land cost, population density, accessibility, safety, cleanliness, and disaster risk. Data were collected from both field surveys and official government publications. The findings reveal that the COPRAS method provides reliable and objective assessments among the evaluated alternatives, with Medan Area emerging as the most suitable location for supermarket development. Overall, this study broadens the practical scope of the COPRAS method in a different regional context and reinforces its reliability and adaptability as a multi-criteria decision-making tool in the modern retail industry.

PT. Tirta Fresindo Jaya, specifically its Pasuruan plant as the producer of Pucuk Harum Tea beverage, requires a large supply of steam to support various production processes. This steam is used in the process of heating tea leaves, heating water through a heat exchanger, and heating chemicals and water in the cleaning in place (CIP) process. Steam pressure of 5 bar that is flowed to the process equipment will undergo condensation to produce condensate. To separate steam and condensate, steam traps are used, consisting of several types, namely mechanical, thermostatic, and thermodynamic. However, in operational practice, steam trap malfunctions often occur, either in the form of steam leaks that are wasted with condensate or failure to drain condensate from the system. This condition causes a decrease in the efficiency of the steam piping system and increases the workload of the boiler. As a result, fuel consumption and boiler feed water requirements become greater than ideal conditions. Therefore, this study aims to analyze the energy and operational losses caused by steam trap malfunctions, as well as evaluate their impact on boiler system performance and steam utilization efficiency at PT. Tirta Fresindo Jaya Pasuruan plant.      

Vocational education in Vocational High Schools (SMK) requires innovative, interactive, and industry-relevant learning media to support students’ independent and competency-based learning. However, learning activities in the subject Communication in the Workplace for Grade XI MPLB at SMKN 62 Jakarta are still dominated by lecture-based methods with limited instructional media, resulting in low levels of student independence and understanding. This study aimed to develop and examine the feasibility, practicality, and effectiveness of an interactive e-book based on Canva for Oral Communication materials in Indonesian Language. The study employed a Research and Development (R&D) method using the ADDIE development model, consisting of analysis, design, development, implementation, and evaluation stages. The research subjects included 36 students in the needs analysis stage, 5 students in the small-scale trial, and 31 students in the large-scale trial. Data were collected through observation, questionnaires, learning outcome tests, and documentation, and analyzed using descriptive qualitative and quantitative techniques. The validation results indicated that the Canva-based interactive e-book was categorized as very feasible, with validation percentages of 100% from the material expert, 88.24% from the media expert, and 95% from the language expert. The small-scale trial showed a practicality percentage of 82.2%, while the large-scale trial reached 88.39%, both classified as very practical. In addition, the pre-test and post-test results in the large-scale trial demonstrated an increase in students’ average scores and a higher number of students achieving the Minimum Mastery Criteria (KKM). Therefore, the Canva-based interactive e-book is feasible, practical, and effective as a learning medium to enhance students’ understanding, motivation, and independent learning in Oral Communication for vocational high school students.

Syncope or fainting is a common clinical problem in children and adolescents, as many as 15% of children experience at least one episode before the end of adolescence. The purpose of this community service is to provide HIPOS (Hydration, Positioning, & Stress Management) Training with the 3E Method (Explain, Example, Experience) on Syncope First Aid Skills given to PMR Members at SMKN 1 Ngasem. The training was carried out for 2 days. The first day consisted of providing training to selected PMR cadres. On the 2nd day, PMR cadres provided training to all PMR members at SMKN 1 Ngasem and also evaluated their ability to perform syncope first aid. The results of the pre-test and post-test showed a significant increase in ability, namely during the pre-test almost all (76.7%) had sufficient ability and after the post-test almost all had good ability (83.3%). It can be concluded that HIPOS (Hydration, Positioning, & Stress Management) training using the 3E method (Explain, Example, Experience) can improve First Aid Skills for Syncope among Red Cross (Red Cross) members at SMKN 1 Ngasem.

Sharia economic education and access to healthcare services are critical components for community empowerment, especially in rural areas like Balapulang Wetan. The Community Service Program (PKM) implemented by STIES Putera Bangsa Tegal in collaboration with Klinik Azzahra integrates sharia economic education with free healthcare services to address the twin challenges of low sharia economic literacy and limited access to quality healthcare. This program employs training and outreach methods alongside provision of basic free health services to the community. Evaluation results indicate increased understanding of sharia economic principles, including zakat, infaq, and financial management, as well as greater utilization of free healthcare services. This holistic approach fosters economic independence and enhances the overall quality of life through improved economic welfare and health. Collaboration among educational institutions, health service providers, and local government forms the foundation for the sustainability and success of this program in creating an inclusive and equitable community empowerment ecosystem.

State-based conservation in Indonesia often faces institutional failure and social resistance, resulting in continued deforestation. Conversely, Indigenous conservation models in West Java, specifically the Leuweung Larangan (forbidden forest), demonstrate significant ecological resilience. However, the legal standing of these customary practices within Islamic jurisprudence remains under-theorized, creating a dichotomy between Adat (custom) and Sharia. This study proposes a juridical reconstruction of the Sundanese taboo mechanism (Pamali) as Jarimah Ta’zir (discretionary sanction) to strengthen environmental law enforcement. Utilizing a socio-legal approach and ecological hermeneutics, this research analyzes Yusuf al-Qardhawi’s concept of Fiqh al-Bi’ah and Seyyed Hossein Nasr’s sacred science, alongside relevant empirical data on Indigenous forest governance. The findings demonstrate that Leuweung Larangan structurally manifests as Hima Syar’i (sacred protected zone). Operationally, Pamali functions not merely as a cultural myth, but as a preventive legal instrument (Sadd al-Dzari’ah) where environmental violations constitute religious criminal acts. This creates a "Sundanese Eco-theology" model that establishes a double-layered compliance system—social sanctions and theological liability—proving more effective for carbon preservation than state regulations alone. The study recommends integrating this model into the Green Constitution framework to resolve tenurial conflicts and enhance climate resilience.

The phenomenon of the dual role of wives is a complex social reality amidst the patriarchal culture that is still deeply rooted in Indonesian society. In this social system, women often bear the double burden of domestic responsibilities as well as public roles, which often gives rise to gender inequality, role conflict, and psychological stress. This article aims to analyze the dual role of wives in a patriarchal culture using a gender perspective and maqasid sharia as an analytical framework. The research method used is a literature study with a qualitative-descriptive approach to various relevant literature. The results of the study indicate that patriarchal culture tends to limit access and recognition of women's roles, thus contradicting the principle of gender justice. Meanwhile, maqasid sharia emphasizes the values ​​of balance, justice, and benefit in husband-wife relations. The principles of hifz ad-din, hifz an-nafs, hifz al-aql, hifz an-nasl, and hifz al-mal provide theological legitimacy for women's social and economic roles as long as they are carried out within the framework of justice, shared responsibility, and family harmony.  

A community service program (PKM) entitled "Skincare Product Dispute Resolution" was successfully implemented in Ngadi Village, Mojo District, Kediri Regency, involving village cadres, youth organizations, and community members, particularly housewives as skincare consumers. This PKM aims to provide solutions to skincare product disputes through five stages: outreach, training, technology implementation, mentoring, and sustainability evaluation. The outreach program began with a presentation on halal skincare products and consumer protection against misleading promotional practices, delivered by speakers from the Sharia Research Group (SReG) and the Non-Governmental Consumer Protection Organization. This program also includes in-kind and in-cash contributions, including training to improve customer service quality, ensure raw material quality standards and production processes comply with international standards, and ensure product information transparency. In addition, a loyalty program and transportation cost incentives were provided to affected consumers. PKM partners played an active role in providing information and inviting the community to participate in this activity. The implementation of this activity is expected to strengthen consumer trust and ensure protection of consumer rights related to skincare products.

International criminal law is a crucial instrument within the international legal system designed to address serious crimes that transcend national jurisdiction, such as genocide, war crimes, and crimes against humanity. International criminal law serves as a means to uphold justice, maintain international order, and prevent impunity for perpetrators of serious crimes that have a broad impact on the global community. This study aims to examine the enforcement of international criminal law in the modern era, emphasizing law enforcement mechanisms and the role of cooperation between states and international institutions. The research method used is normative juridical research, with an approach to relevant laws and regulations, legal doctrine, and court decisions. The results indicate that the effectiveness of international criminal law enforcement still faces various obstacles, primarily stemming from state political interests, weak commitment to international cooperation, and inconsistencies between legal norms and their implementation. The principle of complementarity is a fundamental element of this system, as it positions states as the primary actors in the prosecution process, while international judicial institutions play a complementary role if national mechanisms are ineffective. Furthermore, harmonization of national laws with international criminal law provisions and strengthening cross-border cooperation are determining factors in the success of law enforcement. This study concludes that synergy between states and international institutions, accompanied by strong political commitment, is a key prerequisite for the realization of a just and sustainable international criminal law enforcement system.

Arabic holds an important position in Islamic education as the language of the Qur'an and Hadith. However, the teaching of Arabic in Islamic educational institutions often focuses only on linguistic aspects, thus not fully achieving the goals of comprehensive Islamic education. This study aims to analyze the strengthening of Arabic language education objectives from the perspective of Islamic Tarbiyah. The method used in this study is qualitative, with a literature study and descriptive analysis approach. The analysis was conducted on relevant sources. The findings indicate that Arabic education within the framework of Islamic Tarbiyah not only emphasizes mastery of language skills but also the importance of shaping students' faith, morals, and Islamic character. The integration of tarbawi values into the objectives, materials, methods, and evaluation of learning becomes a key element in creating Arabic language education that is valuable and aligned with the goals of Islamic education. Its implications are expected to serve as a reference for curriculum development, teacher competence improvement, as well as the formulation of contextual, integrative, and sustainable Arabic language learning policies in national Islamic educational institutions.

. Film as a mass communication medium not only functions as entertainment, but also as a means of representing power relations in society. Miracle in Cell No. 7 works by Hanung Bramantyo show various forms of official domination and legal inequality which are relevant to be studied through a hegemony perspective. This research aims to describe the forms of hegemony that appear in the film and interpret the social criticism conveyed through the narrative and visualization. The research uses qualitative methods with listening and note-taking techniques, then the data is analyzed through reduction, presentation and drawing conclusions based on Antonio Gramsci's theory of hegemony. The research results show that this film contains four forms of hegemony: ideological hegemony through the instillation of disciplinary values; hegemony of power through apparatus domination and abuse of authority; cultural hegemony through the imposition of a single standard of behavior; and moral hegemony through the formation of ethical judgments that benefit those in power. These findings indicate that films not only present emotional stories, but also present criticism of legal injustice and structural domination. This research confirms that visual media plays an important role in forming public awareness regarding the practice of power in social life.

Arabic holds an important position in Islamic education as the language of the Qur'an and Hadith. However, the teaching of Arabic in Islamic educational institutions often focuses only on linguistic aspects, thus not fully achieving the goals of comprehensive Islamic education. This study aims to analyze the strengthening of Arabic language education objectives from the perspective of Islamic Tarbiyah. The method used in this study is qualitative, with a literature study and descriptive analysis approach. The analysis was conducted on relevant sources. The findings indicate that Arabic education within the framework of Islamic Tarbiyah not only emphasizes mastery of language skills but also the importance of shaping students' faith, morals, and Islamic character. The integration of tarbawi values into the objectives, materials, methods, and evaluation of learning becomes a key element in creating Arabic language education that is valuable and aligned with the goals of Islamic education. Its implications are expected to serve as a reference for curriculum development, teacher competence improvement, as well as the formulation of contextual, integrative, and sustainable Arabic language learning policies in national Islamic educational institutions.

. Film as a mass communication medium not only functions as entertainment, but also as a means of representing power relations in society. Miracle in Cell No. 7 works by Hanung Bramantyo show various forms of official domination and legal inequality which are relevant to be studied through a hegemony perspective. This research aims to describe the forms of hegemony that appear in the film and interpret the social criticism conveyed through the narrative and visualization. The research uses qualitative methods with listening and note-taking techniques, then the data is analyzed through reduction, presentation and drawing conclusions based on Antonio Gramsci's theory of hegemony. The research results show that this film contains four forms of hegemony: ideological hegemony through the instillation of disciplinary values; hegemony of power through apparatus domination and abuse of authority; cultural hegemony through the imposition of a single standard of behavior; and moral hegemony through the formation of ethical judgments that benefit those in power. These findings indicate that films not only present emotional stories, but also present criticism of legal injustice and structural domination. This research confirms that visual media plays an important role in forming public awareness regarding the practice of power in social life.