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This article discusses Jesus Christ's sacrifice on the cross as evidence of human atonement and its relevance to believers today. From the perspective of Christian faith, this event is considered a central point in the history of salvation, demonstrating divine grace and justice. Through a search of the meaning of Christ's sacrifice, this article provides a broad understanding of the meaning of Christ's suffering for man's atonement and explains how Christ's sacrifice is concrete evidence of unconditional love and the divine will to blot out human sin. Through the analysis of the meaning of redemption worked out by Jesus Christ, which will expand the theoretical basis of the purpose of Jesus' sacrifice on the cross. This article also provides a theory of the importance of understanding Christ's sacrifice on the cross, thus becoming a reference for believers in terms of faith and belief that through Christ's sacrifice brings redemption to believers. Meanwhile, the relevance of Christ's sacrifice on the cross will also affect several aspects of the believer's life, namely in terms of faith, confession, and holy living. In writing this article, a qualitative approach method is used with a literature study method. The search for the meaning of Christ's sacrifice can be studied from several perspectives, namely the theological perspective, the moral perspective and the psychologist's perspective. From a theological perspective, Christ's sacrifice is a form of God's love for man, so He sent His Son, Jesus Christ, as a sacrifice to redeem believers. So that the work of salvation done by Jesus Christ leads to a victory for believers because they have been redeemed and freed from the power of death, and also becomes a means of improving the relationship between man and God. From a moral perspective, it can be understood that Christ's sacrifice on the cross is an example of sacrifice and an example of love for believers. Thus, this article contributes to the understanding of Christ's sacrifice on the cross as a form of human atonement, and enriches the spiritual life of believers and strengthens faith, motivates spiritual life, and clarifies the moral principles underlying the Christian life.

The Docrtrine of Man and principles discusses the definition of man in the context of the Bible, explaining that man was created by God as a special creature with a body, soul and spirit. There are three views regarding human nature, trichotomy, dichotomy, monochotomy.Sin is defined as a violation of God’s commands, which results in separation. Humans from God and the ongoing negative impacts. Sin has various types and impacts, ranging from God’s judgment to spiritual separation from him.  

Concern for the environment is the responsibility of all parties, both the community, government and related parties. Greening activities are activities to maintain a good environment and provide a good impression of health, beauty and prosperity. Greening activities are carried out using participatory methods involving students and the school. The results of this activity illustrate that this program is not only successful in utilizing abandoned land or making the environment more beautiful, but also successfully increasing the ties of friendship between students and all important elements in the school. The design of the program activities and efforts that have been made by students are expected to provide maximum benefits to the community in the school environment.

Health is a state of health, both physically, mentally, spiritually and socially that allows everyone to live productively socially and economically. Health is based on legal provisions, including health law. The development of criminal acts in the field of health sciences One of the crimes in health law that is rampant is the crime in the field of pharmacy, one of which is circulating pharmaceutical preparations of drugs without a distribution permit. Drugs without a distribution permit cannot be freely traded to the public. This is not without reason, unlicensed drugs must be consumed in the right dosage so as not to endanger the health of the public or the people who consume the drug. This research is a normative juridical research using secondary data through literature studies, namely by using research on various sources of books, laws and regulations related to the crime of producing and distributing pharmaceutical preparations without a distribution permit. From the research conducted, it can be concluded that the application of criminal sanctions against criminal offenders who circulate pharmaceutical preparations without a distribution permit is contained in several laws and regulations, namely, Law No. 17 of 2023 concerning Health and Law No. 36 of 2009 concerning Health as a means of crime prevention. The implementation of this law is expected to ensnare the perpetrators of the crime of distributing pharmaceutical preparations without a distribution permit.

Character strengthening activities through socialization on the prevention of the three educational sins were carried out for approximately 3 consecutive days at several schools in Pasinan Village, Lekok District, Pasuruan Regency, which were attended by elementary/MI students in grades V and VI. The purpose of this activity is so that participants can learn about the three main sins in education and how to avoid or overcome them. This community service activity uses the Participatory Action Research (PAR) method to collect data and provide assistance. During this activity, the students attentively followed the material presentation and looked enthusiastic, especially during the educational video about bullying and the question and answer segment. Through a question and answer session that discusses strategies for combating the 3 major sins in education, the author can assess the extent of students' understanding.

The doctrine of humans and sin from a Christian theological perspective emphasizes that humans are created in the image of God, with free will and moral responsibility. However, through the fall into sin, humans experience separation from God and damage to relationships with others and creation. Sin is understood as a violation of God’s law, resulting in spiritual and physical death. This research explores the concept of original sin inherited from Adam and Eve as well as sinful acts committed by individuals. By referring to the Bible and theological views from various sources, this research provides an understanding of the importance of sin in human life and efforts to restore relationships through God’s grace.

The doctrine of humans and sin from a Christian theological perspective emphasizes that humans are created in the image of God, with free will and moral responsibility. However, through the fall into sin, humans experience separation from God and damage to relationships with others and creation. Sin is understood as a violation of God’s law, resulting in spiritual and physical death. This research explores the concept of original sin inherited from Adam and Eve as well as sinful acts committed by individuals. By referring to the Bible and theological views from various sources, this research provides an understanding of the importance of sin in human life and efforts to restore relationships through God’s grace.

A child's life is very important, and parental attention is also important. Babies need to get nutrition from food every day in the right amount and good quality every day. One way to optimize child growth and development is by giving formula milk. Objective: To determine the effect of formula milk consumption on the nutritional status of toddlers in the Working Area of ​​the Yaro Health Center UPTD, Jaya Mukti Village, Nabire Regency. Method: This type of research is quantitative research using observational analysis research design and cross-sectional study design. The population in the study was 65 toddlers and the selected sample consisted of 65 toddlers using total sampling. The research instruments included questionnaires, anthropometric measuring instruments (digital scales and length boards), stationery and documentation tools. The analysis used the Release Statistical Program For Science (SPSS) type 16.0 application. Results: The study showed that the BB/TB index p-value was 0.00 (<0.05), the BB/A index p-value was 0.00 (<0.05) and the TB/A index p-value was 0.00 (<0.05). Conclusion: There is an effect of giving formula milk on the nutritional status of toddlers based on anthropometric measurements using the Body Weight/Height (BW/TB), Body Weight/Age (BW/U) and Height/Age (BH/U) indices. Suggestion: For parents to pay attention to the appropriateness of the dosage, frequency of giving and sanitation of serving formula milk to achieve optimal nutritional status.

Opioids have sedative properties and can lessen intraoperative nausea and vomiting (IONV), even if they may cause nausea and vomiting. The current work was aimed to evaluate the effect of anxiolytic dose of midazolam on Incidence of intraoperative nausea and vomiting during spinal cesarean section. The study was conducted from October 2023 to April 2024 with approval from the research and ethics committees of the university. once an informed consent form has been signed, full-term (90) pregnant participants were included, and scheduled for cesarean section (CS) under spinal anesthesia at Al-Shifa Private Hospital in Baqubah, Diyala. Data from all participants were analyzed. demographic data was non-significant (P≤0.05) variance in the experimental group compared with the control group. The mean blood pressure in both groups, as it was measured every 10 minutes, starting from 0 to 40 minutes of the operation, and there were no significant (P≤0.05) variance between the two groups. The findings showed that the 27 (60%) cases of Nausea and vomiting in the control group, which revealed a significant (P≤0.05) variance compared with the medazolam group, if the number of cases was 8 (17.8%). We conclude that the incidence of intraoperative nausea and vomiting during cesarean sections performed under spinal anesthesia is significantly influenced by the dosage of anxiolytic drugs.

. Pharmacogenomics, the science that combines genetics with pharmacology, plays a vital role in determining the optimal dosage of drugs for patients, especially those with chronic diseases. In Indonesia, the use of pharmacogenomic approaches is still limited even though the genetically diverse population requires more personalized dosage adjustments. This study aims to analyze the effect of genetic variation on drug response in patients with chronic diseases, such as diabetes, hypertension, and cardiovascular disease, in Indonesia. By collecting and analyzing genetic data and patient clinical data, this study will identify genetic biomarkers associated with drug metabolism and therapeutic effectiveness. The results of this study are expected to provide guidance for more accurate and personalized drug dosage determination, which will ultimately improve therapeutic outcomes and reduce the risk of side effects. This study is also expected to encourage wider adoption of pharmacogenomic approaches in clinical practice in Indonesia, as part of the effort towards more personalized and effective medicine.

In the plastic molding industry, there is a compression molding process to make shoulder tubes for cosmetic products. This research was to determine the effect of dosage duration and press station down parameters on unmolded defects in shoulder extrusion tube products. This research method uses quantitative with an experimental approach. This method is carried out by varying parameter setting dosage duration of 0.25s, 0.30s, 0.35s and press station down of 4 bar, 5 bar, 6 bar. The result od the study found that the parameters of dosage duration, press station down and the interaction of the two variables have a significant effect on unmolded defects. The higher the dosage duration and press station down, the unmolded defects decrease as indicated by the average product weight meeting the standard. The lower two parameters, the more unmolded defects occur, indicating that the average product weight not meet the standard weight tolerance of good products.

Coated tablets are compressed tablets that are coated with a mixture of various substances such as: resin, gum, fillers, sugar, plasticizers, polyols, coloring agents, and flavor enhancers in the active substance. The types of coated tablets that are developing are sugar-coated, thin-coated and enteric-coated tablets. One of the additional materials that plays an important role in making coated tablets is a binder. This review article aims to obtain information and examine what is a good concentration of binder to use in coated tablet formulations. Based on a literature study from several articles collected, it can be concluded that the lactose binder, porang tuber starch, and PVP in several coated tablet dosage formulations, these binders have no effect on the physical properties of the dosage form.

Tablets are one of the most commonly used solid dosage forms of medicine in the pharmaceutical industry. The granulation process commonly used in making tablets is the wet granulation process. The operation method includes mixing the active ingredients and excipients, adding a binder liquid, forming granules, drying and sieving. The methods used in this research are literature research, journal reviews, and analysis of relevant papers carried out during the 2015-2023 period. The aim of this literature study is to determine the process, advantages, limitations and application of wet granulation in the pharmaceutical industry. Based on the results of a literature study, tablet production using the wet granulation method was proven to be an effective technique and is widely used for the production of tablet formulations.      

Background: Work fatigue experienced by intensive care room nurses shows several symptoms that are often experienced when nurses are tired, namely drowsiness, difficulty concentrating and physical fatigue. The sleepiness experienced by the nurse was indicated by frequent yawning and wanting to lie down. The aim of this research is to determine the factors that influence the level of work fatigue of nurses at Mitra Medika Amplas General Hospital in 2022. This research is a type of quantitative research with a cross-sectional approach. The population in this study were all nurses at the Mitra Medika Amplas General Hospital in 2022. The sample in this study was 93 people, using purposive sampling, namely taking samples according to the wishes of the researcher. Data was collected using questionnaires and interviews, then processed computerized. Quantitative data analysis was carried out in 3 stages, namely univariate, bivariate and multivariate analysis using Chi-Square, if p ≤ 0.05 then there is an influence between the dependent and independent variables. Statistical test results: age (p value 0.001), gender (p value 0.002), BMI (p value 0.005, education (p value 0.001), sleep patterns (p value 0.001), length of service (p value 0.001), physical work ( p value 0.009), length of work (p value 0.008), it can be concluded that there is a relationship between age, gender, BMI, education, sleep patterns, length of service, length of work, and the level of work fatigue of nurses at Mitra Medika Amplas General Hospital. 2022. The conclusion of this research is that there is a relationship between age, gender, BMI, education, sleep patterns, length of service, length of work, and the level of work fatigue of nurses at Mitra Medika Amplas General Hospital in 2022. It is recommended that Mitra Medika Amplas General Hospital be able to improve health services as well as existing infrastructure in hospitals

Sludge is a by-product of an activity that comes from the discharge outlet of the flocculation, sedimentation and backwash filtration basins. To determine the volume of sludge contained in one liter of raw water, it is necessary to conduct a Jartest Test by determining the optimum dose of PAC. This water sampling was carried out at the Krian 1 Water Treatment Plant (IPA). Primary data collection is obtained from Imhoff Cone Results data. While for secondary data collection we get from Jartest data.  The manufacture of the coagulant solution used is Poly Aluminum Chloride (PAC). The average turbidity value in February was around 123 NTU and there was an increase in turbidity on the seventh day which reached 237 NTU. The drastic increase in turbidity reached 455 NTU with an average turbidity in March of 130 NTU. The graph shows that there is a significant correlation between the volume of sludge produced during the treatment process and the level of water turbidity. Thus, the researcher suggests further treatment of the remaining sludge which can be done by making a Sludge Drying Bed (SDB).  

Clean water is one of the most basic needs of humans as it is constantly needed in their daily activities to survive. The aim of this study is to ensure the correct dosage of Poly Aluminium Chloride (PAC) for at a certain level of rigidity and to avoid chemical waste. Overall, data analysis shows that the water quality in IPA Krian is well awake and in line with applicable standards. This reflects an effective water quality management and monitoring system at the site, with proper adjustment of the fluorescent dosage and the implementation of an efficient water management system.

Sikap bela negara merupakan sebuah tekad dan kesediaan yang diperlukan setiap warga negara untuk berbakti kepada bangsa dan negara. Masyarakat Indonesia, khususnya generasi muda perlu untuk selalu menanamkan nilai-nilai dasar bela negara, meliputi rasa cinta tanah air, sadar berbangsa dan bernegara, setia kepada pancasila sebagai ideologi negara dan pandangan hidup bangsa, rela berkorban, serta memiliki kemampuan awal bela negara. Namun seiring berkembangnya zaman, terjadi krisis kesadaran bela negara pada generasi muda dikarenakan degradasi moral akibat 4 dosa pendidikan yang meliputi perundungan, kekerasan seksual, intoleransi, dan korupsi. Metodologi penelitian yang digunakan adalah metode narrative literature review yang dilakukan dengan mengumpulkan sumber yang relevan dengan topik dan membuat kesimpulan mengenai cara mewujudkan sikap bela negara pada generasi muda dengan menghindari 4 dosa pendidikan. Dari kajian yang telah dilakukan, menghindari 4 dosa pendidikan tersebut, dapat membantu mewujudkan masyarakat Indonesia terutama pada generasi muda agar memiliki kesadaran bela negara yang dicerminkan pada sikap dan perilakunya dalam kehidupan bermasyarakat. Generasi muda juga harus dapat memenuhi perannya sebagai Agent of change, Guardian of value, Iron stock, Social control, dan Moral force dengan cara menghindari 4 dosa pendidikan, sehingga kesadaran bela negara pada generasi muda dapat meningkat, serta menjadi generasi emas yang dapat mempertahankan bangsa dan negara.

Everyone doesn't want something bad to happen in their life. This means that all humans want the best in their lives. Therefore, if people are faced with all the problems in their lives, the word complaining becomes a basic reference in their lives. Feeling that they have no more hope in their lives. It should be noted that such individuals who easily complain when faced with a problem are individuals who have no faith or hope in their lives. In dealing with such individuals, special attention is needed in terms of developing and directing them. If such a person is not directed then don't be mistaken if they are still in the initial position, that is, they are easily carried away and in the end end up doing things that should not be normal. The difference between people who have hope and people who have no hope in their lives is; People who have hope do not easily give up hope in their lives even though the problems they face are very difficult. This is because they still have hope that lifts them from adversity. In contrast, people who have no hope easily give up on circumstances and if the problems they face are too heavy they may choose a shortcut, namely by ending their lives in an unnatural way. Therefore, it is very important in human life to have a solid foundation that is able to provide solutions, even in human helplessness, there are ways to help and lift this downturn.

In drinking water treatment plants, there is a coagulation unit that requires coagulant substances. Coagulant dosage determination can be done using the jartest method. By carrying out a jar test, the correct dose will be known so that the coagulation process runs well, and the use of coagulants can be optimized. This research was carried out by analyzing jartest results from the company's internal laboratory for one week with two variations in jartest times in one day. The raw water used comes from shipping rivers with a company production capacity of 500 l/second. The dosage of Aluminum Sulphate coagulant used in the field is 165 mg/l, while the jastest results show that the optimum dosage is 140 mg/l. This research is expected to provide scientific information regarding determining coagulant dosage at IPAM PT Hanarida Tirta Birawa which makes it easier for installation operators.      

Chili is one of the superior horticultural products which has quite high economic value. The demand for large red chili supplies is causes farmers to plant chilies continuously without paying attention to environmental factors. The use of kasgot fertilizer in the cultivation process can have a positive impact on plants. This research aimed to determine the effect of doses variants for the growth of Capsicum annuum L. The research method used RAL with 6 treatments K1: 150g. K2: 175g, K3: 200g, K4: 225g, K5: 250g, and K6: 275g each treatment was repeated 4 times to obtain 24 samples. Observation parameters include plant height, number of leaves, number of fruit and fruit weight. Data analysis used One Way ANOVA and continued with the Tukey test. Varying doses of kasgot fertilizer have a real influence on the growth parameters of plant height, number of leaves, number of fruit and fruit weight. Treatment with a dose of kasgot fertilizer (K1) 150g gave the highest average number of fruit (10.3 pieces) and fruit weight (82.375g). Meanwhile, a dose of 175g (K2) gave the highest average plant height (37.5 cm) and number of leaves (50.45 each). So the optimal dosage of kasgot fertilizer for the growth of large red chili plants is around 150-175g.