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Fahrur Rijal Ardiyanto; Ginanjar Rochmad Mulyanto; Erlandy Singgih Pradana; Rizky Dany Setyawan; Rini Dwi Lestari +21 more

Pandawa : Pusat Publikasi Hasil Pengabdian Masyarakat 2026 Asosiasi Riset Ilmu Pendidikan Indonesia

The internship program of Universitas Mayjen Sungkono in Begaganlimo Village introduced a training initiative focused on the Development of an Adaptive Learning Platform Based on D-PACK as an effort to enhance the quality of digital learning in Begaganlimo elementary schools. This training was designed to assist teachers in strengthening their ability to design and utilize interactive learning media supported by artificial intelligence (AI). Through this socialization activity, teachers were not only introduced to the use of adaptive technology but also guided to apply it in teaching practices so that the learning process becomes more effective, easier to understand, and more engaging for students. In addition, the socialization activities provided a deeper understanding of how technology can be used and integrated into teaching. Teachers not only learned to operate AI-based applications or devices, but they also gained insight into the pedagogical principles within the DPACK framework, which ensures that technology is applied appropriately. As a result, learning is expected to become easier to understand, more engaging, and capable of increasing students’ participation and motivation in the classroom.

Ari Diana; Wiko Antoni; Susilawati Susilawati

Jurnal Riset Rumpun Ilmu Bahasa 2026 Pusat riset dan Inovasi Nasional

Pantun, as a form of traditional oral literature, plays a crucial role in the development of regional literature learning and character education. This study aims to analyze the application of pantun as a learning medium capable of revitalizing students' character values ​​in the modern era. The study was conducted through a literature review of several relevant scientific articles, including those by Purnama et al. (2023), Andayani (2024), Yoga (2024), and Rozani (2025), all of which discuss the relationship between pantun, learning, and character development. The analysis shows that pantun contains character values ​​such as religiosity, honesty, responsibility, courtesy, hard work, and love of country. Through pantun reciprocal activities, the creation of thematic pantun, and the integration of pantun into a local wisdom-based curriculum, regional literature learning can be an effective means of developing polite, creative, and cultured personalities. The application of pantun in the classroom not only strengthens appreciation for regional literature but also serves as a concrete strategy for revitalizing national character. Thus, pantun is no longer merely a legacy of oral tradition, but rather an instrument for moral and cultural education relevant to the needs of 21st-century education.    

Gabriani Paranda; Gita Massora; Dewi Balandatu; Novrianti T. Mindi; Irmani Gelong Pasande

Sabar : Jurnal Pendidikan Agama Kristen dan Katolik 2026 Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

This study focused on addressing the problem of low self-confidence among seventh-grade students at SMP In Tana Toraja. The issue was identified through several behaviors, such as difficulty in voicing opinions, lack of courage to stand in front of the class, and minimal participation during the learning process. To address the identified issue, the study was designed to enhance students’ self-confidence through group guidance activities incorporating the sociodrama technique. This investigation adopted a Guidance and Counseling Action Research approach implemented across two consecutive cycles, each involving planning, action implementation, observation, and reflection. The participants consisted of 30 students, while data were collected through questionnaires and observation instruments. The results indicated that students’ self-confidence developed progressively over time. In the initial condition, most students were still classified in the low-confidence category, but improvement began to appear in cycle one and became more significant in cycle two. These changes were reflected in students’ increased confidence in performing, better communication skills, and stronger active participation in group activities. The sociodrama technique provides direct social interaction experiences that help students develop their self-confidence. Based on the results, the use of group counseling activities incorporating sociodrama emerges as a viable strategy for school counselors to support the development of students’ self-confidence.

Juniati Juniati; Erwin Ambalinggi; Asyumi Febrianti

Sabar : Jurnal Pendidikan Agama Kristen dan Katolik 2026 Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

The development of a student's personality, particularly during classroom interaction, is heavily influenced by their level of self-confidence. A lack of self-assurance often leads to public speaking anxiety, which subsequently restricts student engagement and diminishes academic performance. This phenomenon is frequently identified among tenth-grade Vocational High School (SMK) students who are navigating a period of environmental transition. This research focuses on enhancing the self-confidence of Grade X SMK students struggling with speech-related anxiety through the implementation of group guidance services utilizing role-playing methods. The study follows a Guidance and Counseling Action Research (GCAR) design conducted over two cycles, consisting of preparatory, executive, monitoring, and evaluative phases. The participants were tenth-grade students with low self-confidence profiles as determined by questionnaires and field observations. Data were analyzed using a descriptive quantitative approach to compare performance levels before and after the intervention. The results demonstrate that group guidance integrated with role-playing is an effective strategy for optimizing student self-confidence, as shown by the consistent upward trend in scores throughout the cycles. These findings suggest that this technique serves as a strategic instrument for school counselors to mitigate social anxiety among students. 

Beny Rahman Hakim

Modem : Jurnal Informatika dan Sains Teknologi 2026 Asosiasi Profesi Telekomunikasi Dan Informatika Indonesia

The development of information technology has become a primary pillar in enhancing corporate operational efficiency, where rapid and accurate data integration significantly determines business competitiveness. Case study in PT Gawi Anjung Bersama (GAB) revealed that the company is facing operational constraints because the management of delivery orders and invoices still relies on conventional office applications such as Microsoft Excel and Word. This procedure causes hurdles in data sharing among staff and results in low information security due to the absence of integrated access control settings. This research aims to design and develop the Gawi Anjung Bersama Information System (SIGAB), a web-based system implementing the CodeIgniter framework. The system is developed using Waterfall model, encompassing stages from analysis, design, and implementation to testing. The research flow starts with problem identification, primary and secondary data collection, and functional and non-functional requirements analysis. The system is designed using Unified Modeling Language (UML) modeling, specifically Use Case and Class Diagrams, as well as Entity Relationship Diagrams (ERD) for the database. The system interface is designed as wireframes on Figma web. This system separates access rights into three main actors namely owner, administrator, and staff, to ensure data security. Blackbox testing results, conducted after the system was hosted, indicate that all functional features operate as intended. The implementation of SIGAB is expected to optimize the management of delivery orders and invoices at PT GAB.

Ilham Saputra; Anita Qoiriah

Merkurius : Jurnal Riset Sistem Informasi dan Teknik Informatika 2026 Asosiasi Riset Teknik Elektro dan Informatika Indonesia

The proliferation of online gambling promotional comments on Indonesian social media has become a serious issue requiring fast and accurate automated handling. This study aims to implement a Hybrid Recurrent Neural Network (RNN) and Long Short-Term Memory (LSTM) method to classify online gambling comments and compare its performance with standalone RNN and LSTM models. The research utilized a dataset of 10,230 comments subjected to comprehensive preprocessing stages, including the normalization of non-standard language using a slang dictionary. Testing was conducted across three data-splitting scenarios: 90:10, 80:20, and 70:30. Experimental results demonstrate that the standalone LSTM model achieved the highest average accuracy of 97.45%. However, the Hybrid RNN–LSTM model showed significant superiority in terms of performance stability, yielding the lowest standard deviation (0.0027) and the smallest Coefficient of Variation (0.28%) across all scenarios. These findings indicate that while the LSTM architecture is highly effective at capturing short-text context, the Hybrid approach provides better robustness against fluctuations in data proportions, making it highly relevant for implementation as an automated detection system on social media.

Silvi Ferislan; Fauziah Fauziah; Irma Andriani

Jurnal ilmu Kesehatan Umum 2026 Asosiasi Riset Ilmu Kesehatan Indonesia

Aggressive behavior is one of the manifestations commonly found in individuals with mental disorders, and this can potentially cause harm both to themselves and to their surroundings. To address this condition, one non-pharmacological approach that can be implemented is the use of Mozart classical music therapy. This study aims to evaluate the impact of Mozart classical music therapy on patients who have the potential to exhibit violent behavior at Aceh Mental Hospital. The research activities were conducted from July 2 to 5, 2025. The research design adopted in this study is pre-experimental using the One group pretest-posttest Design method. The study subjects consisted of 15 inpatients who had been identified as being at risk for violent behavior, with sample selection carried out through purposive sampling. The findings of the study showed that the average score of signs and symptoms before the intervention was 5.73, with a score range of 3 to 8. After the intervention in the form of Mozart classical music therapy, the average score of signs and symptoms decreased significantly to 1.60, with a range between 1 and 2. Statistical analysis using the Wilcoxon Signed Rank test showed a Z value of -3.437 with a significance level of P = 0.000 (P < 0.05). Based on these results, it can be concluded that Mozart classical music therapy has a significant effect in reducing the risk of violent behavior in patients. Therefore, Mozart classical music therapy is recommended as an effective supportive intervention and can be routinely integrated into psychiatric care rooms.

Akbar Nazaruddin; Albertus Juvensius Pontus; Agus Winarno; Tommy Trides; Lucia Litha Respati

Venus: Jurnal Publikasi Rumpun Ilmu Teknik 2026 Asosiasi Riset Ilmu Teknik Indonesia

Slope stability studies are crucial in determining the sustainability and operational safety of mining activities. This research was conducted to analyze the correlation between rock porosity and Unconfined Compressive Strength (UCS) results, as well as the corrleations between Point Load Index (PLI) and Unconfoned Compressive Strength (UCS) results. These two correlations form the primary components of the study. Three types of rock were tested claystone, coal, and siltstone. The results of the study are as follows for the correlation between porosity and Unconfoned Compressive Strength (UCS), claystone yielded a coefficient of determination (R2) of 0.32 is classified as weak correlation, with the linear regression equation Y=-0.11X+6.98. Coal yielded an (R2) of 0.56 is classified a moderate correlation, with the equation Y=-1.98X+103.77. Siltstone yielded an (R2) of 0.86 is classified a strong correlation, with the equation Y=-0.38X+20.02. Regarding the correlation between Point Load Index (PLI) and Unconfoned Compressive Strength (UCS), claystone achieved an (R2) of 0.12 is classified a very weak correlation, with the linear regression equation Y=8.91X. Coal achieved an (R2) of -0.27 is classified a very weak correlation, with the equation Y=27.87X. Lastly, siltstone achieved an (R2) of -0.45 is classified a very weak correlation, with the linear regression equation Y=24,90X.

Tiarnita Maria Sarjani Br Siregar; Tetty Aprilya Rezeki Simatupang; Rani Natalia Purba; Niko Alriadi Sinaga

International Journal of Education and Literature 2026 Lembaga Pengembangan Kinerja Dosen

English learning at the elementary school level plays an important role in developing students’ early language competence, particularly in listening skills as the foundation for other language abilities. However, many learning processes still rely on conventional teaching methods that do not fully accommodate the developmental characteristics of young learners, resulting in limited engagement and listening comprehension. Therefore, this study aims to analyze the role of storytelling in improving English listening skills among elementary school students and to identify effective implementation strategies in classroom learning. This research employs a library research method by reviewing and analyzing various relevant literature sources, including books, scientific journals, and previous research findings related to storytelling in English language learning. The analysis shows that storytelling contributes significantly to improving students’ listening comprehension, vocabulary acquisition, attention, and learning motivation. Through structured narratives, expressive delivery, and the support of visual media, storytelling creates a contextual and meaningful learning environment that helps students understand spoken English more effectively. The findings also indicate that the effectiveness of storytelling is closely related to the developmental characteristics of elementary school students who learn better through concrete, imaginative, and engaging experiences. Furthermore, the implementation of storytelling through systematic stages pre-listening, while-listening, and post-listening can enhance students participation and comprehension during the learning process. In conclusion, storytelling can be considered an effective instructional strategy for improving English listening skills among elementary school students while also supporting vocabulary development and creating an engaging learning atmosphere.

Widya Isma Dayanti; Husnul Hotimah; Rudi Khobiron; Mu’alimin Mu’alimin

Ikhlas : Jurnal Ilmiah Pendidikan Islam 2026 Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

Due to its focus on the psychological components of leadership, motivation, communication, and human resource development in educational institutions, management psychology is becoming an increasingly significant perspective in educational management. The use of management psychology in the classroom is considered crucial for improving organizational performance and teacher motivation. The purpose of this study was to investigate how management psychology can enhance teacher work motivation and its impact on school efficacy. This study reviewed previous research on the use of management psychology in education using a qualitative approach and literature review methodology. Using keywords related to management psychology in education, teacher motivation, educational leadership, and educational organizational performance, systematic search of scientific publications published in the Google Scholar database between 2022 and 2026 was used to collect data. Identification, screening, eligibility evaluation, and final selection of relevant publications were all steps in the literature selection process. Thematic coding techniques were used to examine six selected publications to determine the main findings, methodology, and research emphasis of each study. The findings suggest that the use of management psychology in educational management techniques, such as effective communication, teacher empowerment, supportive leadership, and the establishment of equitable reward systems, can significantly enhance teacher motivation and foster a positive work environment. In addition, these approaches increase the effectiveness of educational institutions, improve teacher performance, and foster collaboration within the school environment. To promote teacher professional development and raise the overall standards of educational institutions, it is crucial for educational administrations to incorporate a psychological perspective.

Naela Farkhati; Agus Supriatna

Jurnal Ekonomi dan Keuangan 2026 Asosiasi Riset Ekonomi dan Akuntansi Indonesia

This study aims to analyze the effect of financial literacy and lifestyle on financial management of students of the Management Study Program at Universitas Pamulang. This research uses a quantitative method with an associative approach, with data collected through questionnaires distributed to 160 respondents. Data analysis was conducted using validity tests, reliability tests, classical assumption tests, simple and multiple linear regression analysis, t-test, F-test, and coefficient of determination (R²). The results show that partially financial literacy has a positive and significant effect on financial management with a t-value of 7,161 > t-table 1.975 and a significance value of 0.000 < 0.05, while lifestyle also has a positive and significant effect with a t-value of 6,881 > t-table 1.975 and a significance value of 0.000 < 0.05. Simultaneously, financial literacy and lifestyle have a significant effect on financial management with an F-value of 853.671 > F-table 3.05 and a significance value of 0.000 < 0.05. The coefficient of determination of 0.916 indicates that 91,6% of the variation in students’ financial management is explained by financial literacy and lifestyle, while the remaining 8,4% is influenced by other factors outside this study.

Kholidah Hannum Hasibuan; Anhar Nasution; Putra Halomoan Hasibuan

International Journal of Education and Literature 2026 Lembaga Pengembangan Kinerja Dosen

This study examines the integration of religious moderation values in Islamic Religious Education (PAI) and its impact on students’ religious tolerance in public junior high schools in Padangsidimpuan City. The research is based on the need to foster tolerance, mutual respect, and harmonious coexistence among students from diverse religious and social backgrounds. Using a qualitative field research approach, the study was conducted in several public junior high schools. Data were collected through interviews, observations, and documentation involving principals, PAI teachers, and students. Data analysis followed the stages of data reduction, data presentation, and conclusion drawing, with validity ensured through triangulation. The findings reveal that religious moderation values have been integrated into the planning, implementation, and evaluation stages of PAI learning. Teachers incorporate key values such as tolerance, justice, moderation, deliberation, equality, and anti-violence into both teaching materials and classroom practices. This integration has led to positive outcomes, including increased mutual respect among students, reduced conflicts, and a more harmonious learning environment. Overall, PAI learning plays a significant role in shaping students’ character, promoting moderate attitudes, and strengthening religious tolerance in a diverse school setting.

Dita Hendriani; Dwi Junianto

Jurnal Pengabdian dan Pembangunan Lokal 2026 Lembaga Pengembangan Kinerja Dosen

Abstract: Lesson Study is a collaborative process where teachers identify learning problems, plan improvements, implement instruction with one teacher teaching and others observing, evaluate, revise, re-teach, re-evaluate, and disseminate results. This method serves as a reference for HOTS-based classroom instruction aimed at enhancing learning motivation, student achievement, and critical thinking. The community service was conducted at the Tadris Social Sciences Study Program, FTIK, UIN Sayyid Ali Rahmatullah, and MI Podorejo, Sumber Gempol, Tulungagung, through planning, implementation, and reflection stages. This study employed a descriptive qualitative method with a sequential design covering preparation, micro-teaching training, school mentoring, Lesson Study implementation, and comprehensive final evaluation. Observations from this Lesson Study revealed that students demonstrated critical thinking and active participation in learning. This activity is expected to foster synergy among lecturers, teachers, and pre-service teachers in designing, implementing, and evaluating teaching-learning activities, making instructional methods more creative, innovative, and adaptive to technological advancements.

Tiarnita Maria Sarjani Br.Siregar; Siti Afiqa Rahmah Manik; Habibah Rusly Elly; Anthony Chornelius Nadeak; Nazwi Haliza Purba +1 more

International Journal of Education and Literature 2026 Lembaga Pengembangan Kinerja Dosen

This study aims to systematically examine empirical evidence on the effectiveness of role play in improving EFL students' speaking skills. Using Systematic Literature Review (SLR) methodology guided by the PRISMA framework, this study analyzed 20 peer-reviewed articles obtained from Google Scholar, ERIC, and Scopus databases. Inclusion criteria focused on studies investigating role play as an instructional technique targeting speaking skills in EFL or ESL contexts. Findings reveal that role play consistently and significantly improves key speaking components including fluency, accuracy, pronunciation, vocabulary, and confidence. Additionally, role play reduces speaking anxiety and promotes a more communicative and interactive learning environment. This review also identifies moderating factors such as class size, student proficiency level, and teacher facilitation quality that influence role play effectiveness. These findings suggest that role play is a highly effective pedagogical strategy for improving speaking competence, particularly in EFL contexts, and its systematic integration into curriculum design is strongly recommended.

Ilma Rizka Ramadhanti; Nasihudin Nasihudin; Ani Yanti Ginanjar

Mutiara Pendidikan dan Olahraga 2026 Asosiasi Riset Ilmu Pendidikan Indonesia

This study aims to improve student engagement and learning outcomes in the subject of Natural and Social Sciences (Ilmu Pengetahuan Alam dan Sosial / IPAS) through the implementation of the Auditory, Intellectually, Repetition (AIR) learning model in a fourth-grade elementary school class. The initial problem indicated that student engagement in learning was still low, at 37.5%, with learning mastery reaching only 33.3% and an average class score of 68.0, which did not meet the Minimum Mastery Criteria (KKM) of 75. Therefore, improvement efforts were needed through the implementation of a more active and student-centered learning model. This study employed a Classroom Action Research (CAR) approach conducted in two cycles, where each cycle consisted of planning, action, observation, and reflection stages. The research subjects were 24 fourth-grade students. Data collection techniques included observation of student engagement, learning outcome evaluation tests, field notes, and documentation. Student engagement data were analyzed using percentages, while learning outcomes were analyzed through mean scores and the percentage of classical learning mastery. The results showed a significant improvement in each cycle. In Cycle I, student engagement increased to 62.5%, with learning mastery reaching 54.17% and an average score of 74.29, although it had not yet achieved classical completeness. In Cycle II, student engagement increased to 87.5%, with learning mastery reaching 100% and an average score of 85.42. These improvements indicate that the implementation of the AIR model was able to gradually and sustainably enhance both the learning process and outcomes. Based on these findings, it can be concluded that the Auditory, Intellectually, Repetition (AIR) learning model is effective in improving student engagement and learning outcomes in IPAS. This model can serve as an alternative learning strategy to create a more active, systematic, and student-centered learning environment.

Romy Atmansyah Iswandi; Demonius Sarumaha; Saiful Amir

Modem : Jurnal Informatika dan Sains Teknologi 2026 Asosiasi Profesi Telekomunikasi Dan Informatika Indonesia

This study analyzes the performance of the Dual Modulus RSA algorithm in securing text data using Python. The rapid growth of digital technology has increased the risk of data security threats, making efficient and secure encryption essential. Dual Modulus RSA is a modification of the classic RSA algorithm that uses two different moduli in the encryption and decryption process, thus increasing security levels because attackers must factorize two moduli simultaneously. This research uses an experimental quantitative approach by measuring the execution time of encryption and decryption processes with variations in plaintext length (5, 10, and 15 characters). Implementation was carried out using Python 3 with the time.perf_counter() function for microsecond-precision measurement. The results show that the Dual Modulus RSA algorithm successfully encrypts and decrypts all test plaintexts correctly. Encryption time ranged from 0.0212 ms to 0.0823 ms, while decryption time ranged from 0.0422 ms to 0.0955 ms. There is a positive linear relationship between plaintext length and processing time. Decryption is consistently slower than encryption due to the larger private key exponent (d1=2753, d2=3533) compared to the public exponent (e=17). The main factors affecting performance are exponent size, dual modulus overhead, CPU caching effects, and Python interpretation overhead. This study recommends using Dual Modulus RSA with hybrid encryption for practical implementation to balance security and performance.

Septia Wahyuni; Delfia Herwanis; Al Musanna; Suminah Suminah; Rahmanita Zakaria +1 more

International Journal of Education and Literature 2026 Lembaga Pengembangan Kinerja Dosen

Curriculum reform in Indonesia has repeatedly emphasized flexibility, deep learning, and student-centered instruction. Nevertheless, many reforms have not been translated effectively into classroom practice. Existing studies tend to focus on teacher competence and policy readiness, while the deeper dimension of teacher beliefs remains underexplored. This study aims to unpack how teacher beliefs shape responses to curriculum reform and to identify the belief-related factors that influence the success or failure of curriculum innovation. A qualitative descriptive design was employed using pre-Delphi reflective questionnaires and Focus Group Discussion data involving senior secondary school teachers and educational stakeholders. Data were analyzed thematically to identify recurring patterns of belief, challenge, and adaptation. The findings reveal that teacher beliefs constitute the most decisive factor in curriculum implementation. Three major themes emerged: (1) a persistent gap between curriculum policy and classroom practice, (2) the difficulty of transforming teachers’ mindsets from fixed to growth-oriented perspectives, and (3) the construction of an ideal teacher identity characterized by reflection, adaptability, collaboration, and moral commitment. More importantly, teachers viewed curriculum change not merely as a technical demand, but as a moral and spiritual responsibility. Curriculum reform will remain ineffective unless it addresses teachers’ internal beliefs. Sustainable transformation requires professional development that integrates cognitive, emotional, and spiritual dimensions of teaching.      

Andreas Afriyanto Moa; Fitriah Fitriah; Mariana Sada

Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam 2026 Pusat riset dan Inovasi Nasional

This study aims to determine the extent of the role of the school environment in influencing the learning motivation of class X students in Muhammadiyah Maumere High School. The school environment is an external factor that plays an important role in supporting or inhibiting the learning process of students. The factors studied in this study include the physical condition of the school (such as classrooms, libraries, laboratories, and sports facilities), social aspects (support of teachers and peers), as well as psychological aspects (comfort, appreciation, and conducive learning atmosphere). The method used in this study is a qualitative descriptive method with data collection techniques through observation, interviews, and questionnaires to students and teachers. The result of the study shows that school facilities in Muhammadiyah Maumere High School still have many limitations, including inadequate classrooms, lack of learning technology tools such as projectors, small libraries with limited collection of books, and the unavailability of special space for arts and special sport facilities. However, despite these limitations, most students still show a high level of learning motivation. This is influenced by the support of teachers and peers, involvement in extracurricular activities, family support, and personal expectations of student achievement. This study concluded that the school environment indeed plays an important role in shaping student learning motivation, but social and psychological factors also have a big influence. Therefore, it is recommended that schools make improvements and develop physical facilities and strengthen positive social climate to support the student learning process optimally. 

Nerdy Nerdy; Nilsya Febrika Zebua; Rini Karlina Putri Zega; Nabilah Dinda Ramadani; Sara Ariska Purba +2 more

Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam 2026 Pusat riset dan Inovasi Nasional

This study aims to comprehensively evaluate the potential pharmacological activities and safety profiles of seven secondary metabolite compounds (Caffeic Acid, Syringic Acid, Quercetin, Luteolin, p-Coumaric Acid, Ferulic Acid, and Epicatechin) identified in the Bajakah plant (Spatholobus littoralis Hassk.). The research approach integrates in silico analysis using the PubChem database, biological activity prediction via PASS Online, oral toxicity assessment through ProTox-II, and pharmacokinetic evaluation using pkCSM, which were subsequently validated through an empirical literature review. The results indicate that these compounds exhibit significant activity probabilities, particularly as antimutagenic, antiseptic, and antioxidant agents. Luteolin demonstrated the highest antimutagenic potential, while Quercetin showed dominant antioxidant activity. Toxicity profiling revealed that Luteolin and Caffeic Acid possess the highest safety levels (Class 5), whereas Quercetin requires special attention (Class 3). These computational findings strongly correlate with empirical evidence demonstrating that Bajakah extract exhibits broad-spectrum antibacterial activity against Staphylococcus aureus, antifungal activity against Candida albicans, as well as high antioxidant and anti-inflammatory capacities. This study provides a strong molecular foundation for the development of Bajakah as a safe and effective phytopharmaceutical candidate.

Nilsya Febrika Zebua; Nerdy Nerdy; Lidia Muliani; Dikxi Putri Mulyana; Fathur Raihan Amri +1 more

Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam 2026 Pusat riset dan Inovasi Nasional

This study aims to analyze the in silico profile of the compound orientin derived from the water hyacinth plant (Eichhornia crassipes) as a potential antioxidant candidate. Orientin was selected based on its chemical structure data registered in PubChem, which provides complete information regarding molecular identity, physicochemical properties, and 2D and 3D structural representations. The prediction of biological activity was conducted using PASS Online, which indicated that orientin possesses a promising likelihood of exhibiting antioxidant activity according to relevant probability values. Furthermore, the safety assessment of the compound was carried out through ProTox-II to identify potential toxicity, including toxicity class, possible hepatotoxic effects, and other predicted safety parameters. To determine its pharmacokinetic profile, pkCSM was employed to predict ADMET characteristics such as absorption, distribution, metabolism, excretion, and additional toxicity risks. The results of these analyses show that orientin demonstrates favorable potential as an antioxidant candidate, supported by predicted pharmacological properties and relatively low toxicity levels according to in silico evaluations. Therefore, orientin has promising potential for further development in subsequent in vitro and in vivo studies.