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M. Fatahila Surya Asmara; Dyah Hendrawati; Florino Piscal Akbar

SARGA: Journal of Architecture and Urbanism 2026 Universitas 17 Agustus 1945

Kenyamanan termal dalam ruangan sangat penting untuk efektivitas kinerja pengguna ruang, terutama bangunan masjid yang digunakan untuk beribadah oleh banyak orang. Sistem peghawaan alami yang memanfaatkan aliran udara dan desain fasad yang baik sangat berperan dalam menciptakan lingkungan yang nyaman. Penelitian ini bertujuan untuk mengoptimalkan fasad Masjid Quwwatul di Yogyakarta guna mencapai kenyamanan termal. Metode simulasi menggunakan perangkat lunak Autodesk CFD untuk mengukur kecapatan udara sebagai variabel kenyamanan termal, dan menggunakan CBE untuk mengukur kenyamanan termal pada ruang ibadah. Hasil menunjukkan bahwa fasad eksisting belum mencapai kenyaman termal, dengan aliran udara masuk hanya sebesar 0,74 m/s. Alternatif desain fasad diperlukan untuk meningkatkan aliran udara. Alternatif 1 dapat meningkatkan aliran udara menjadi 1,22 m/s dengan memperbesar bukaan sebesar 13% dan menggunakan sistem ventilasi silang, sehingga dikategorikan sebagai nyaman hangat. Alternatif 2 dapat meningkatkan aliran udara menjadi 1,3 m/s dengan memperbesar bukaan sebesar 19% serta menggunakan sistem bodycooling dan ventilasi silang, sehingga masuk ke dalam kategori nyaman hangat.

Ajeng Atma Kusuma; Aini Adila Rusydiana; Rizka Nur Aziza; Zahra Syifa Aulia; Nuha Nadhifah

Proceeding of the International Conferences on Engineering Sciences 2026 Asosiasi Riset Ilmu Teknik Indonesia

The development of artificial intelligence technology is a great opportunity for the fashion industry, especially in designers based on personalization and consumer needs. This study aims to examine Midjourney's AI technology in the design personalization process by integrating solid data and consumer style preferences. This research is expected to support the concept of mass customization in the fashion industry and increase the relevance of design to user character. This research uses a mixed method method by combining quantitative data and qualitative data. The research stages include body data collection and style preferences, prompt formulation, data-driven prompt formulation, design generation using Midjourney, design validation by experts and consumers, and integrated data analysis.The results showed that the majority of the designs produced were considered feasible in terms of construction (83%) and in accordance with the character of the consumer's body (75%). The modest and minimalist style categories received the highest personalization scores. The qualitative findings reinforce the quantitative results, showing that consumers feel the fit of the style and proportions of the design with the character of their bodies.The study concludes that Midjourney's AI integration in the fashion design process is able to effectively support design personalization, although it still requires the role of designers in technical refinement. This approach has the potential to be an innovative solution in the development of data-driven fashion design.

Moh Zainuddin; Mokhamad Nur Bawono; Heri Wahyudi; Roy Januardi Irawan

Mutiara Pendidikan dan Olahraga 2026 Asosiasi Riset Ilmu Pendidikan Indonesia

The 50 meter freestyle is a sprint event that requires explosive strength, efficient technique, and optimal body stability. Arm muscle strength contributes directly to propulsion, while core muscle strength supports stability and force transfer. This study aimed to analyze the influence of arm and abdominal muscle strength on 50-meter freestyle swimming performance among athletes of the Science Swimming Team (SST) Sidoarjo. A quantitative correlational design was employed with a sample of 10 athletes aged 10–12 years (5 males, 5 females). Arm muscle strength was measured using the pull-up test, abdominal strength with a 30-second sit-up test, and swimming performance with the best time in a 50-meter freestyle trial. Data were analyzed using Spearman correlation and multiple linear regression with a 0.05 significance level. Results indicated a significant correlation between arm strength and swimming performance (r = 0.773; p = 0.009), while abdominal strength showed a positive but non-significant correlation (r = 0.609; p = 0.062). Regression analysis revealed that both variables together explained 57.7% of the variance in swimming speed. It is concluded that arm muscle strength has a dominant influence on freestyle sprint performance, whereas core muscles serve as supporting factors for stability and efficiency. These findings highlight the importance of integrated training programs combining arm and core strengthening to optimize sprint performance in young swimmers.

Ardha Pangestu; Hardono Hardono

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

The prevalence of diabetic ulcers in Indonesia reaches 12-15% of all sufferers. This condition has an impact on the patient's psychological condition in the form of anxiety due to wounds that are difficult to heal, changes in body image, and concerns about the possibility of amputation. One of the nonpharmacological interventions that can help overcome anxiety is the slow deep breathing technique. The purpose of writing this scientific paper is to carry out Nursing Care for Mrs. M with Diagnosis of Diabetic Ulcers using the application of slow deep breathing intervention in reducing anxiety at Az-Zahra Hospital. The writing method is a nursing care process that includes the stages of study, nursing diagnosis, planning, implementation, and evaluation. The subject of care was Mrs. M, a patient with diabetic ulcers in the inpatient room of Az-Zahra Hospital. Data collection was carried out through interviews, observations, documentation studies, and physical examinations, and using a medical-surgical nursing care assessment format. The ethical principles applied use the principles of Nursing Ethics. The results of nursing care showed that after three days of slow deep breathing intervention, patients reported feeling calmer, sleeping better, and anxiety levels decreased from moderate to mild based on observation results and anxiety scales used. This suggests that slow deep breathing interventions are effective in helping to reduce anxiety in patients with diabetic ulcers. It is hoped that patients and families can continue these breathing exercises independently as part of stress management efforts and quality of life improvement.  

Frenky Satria; Rini Dharmastiti

Jurnal Riset Rumpun Ilmu Teknik 2026 Pusat riset dan Inovasi Nasional

Lifting activities are an essential part of manual material handling across various industrial sectors and constitute a primary source of ergonomic risk exposure when performed with inappropriate work postures. The use of hands-off tools such as push-pull sticks is often implemented to maintain a safe distance between workers and loads and to reduce exposure to line-of-fire hazards. However, the implementation of work aids does not automatically ensure neutral work postures, as push-pull techniques, reach distances, and environmental conditions can still lead to awkward postures. This study aims to evaluate the work posture risk in lifting activities using a fiber-composite push-pull stick based on the Rapid Entire Body Assessment (REBA) method. The research was conducted as an observational analytic field study involving nine workers in tubular pushing and pulling activities. Work postures were documented through direct observation and visual recordings, then assessed using REBA to obtain risk scores, risk categories, and required corrective actions. The results indicate that work postures fall into the medium to high-risk categories, with trunk and shoulder components being the dominant contributors. These findings confirm the need for improvements in work methods, ergonomic training, and strengthening of lifting SOPs to optimize the safety and ergonomic benefits of work aids.

Kristina Meni; Tjang, Yanto Sandy; Amandus Suhaedi Dol; Felisitas Yuswanto

Sabar : Jurnal Pendidikan Agama Kristen dan Katolik 2026 Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

This study examines the Ka’Bawakng dance as a cultural–religious expression of the Dayak Kanayatn community that has undergone a deepening of meaning through inculturation within Catholic liturgy. Originating in the Baliatn ritual, Ka’Bawakng dance initially functioned as a medium of healing and cosmological communication that affirmed the interconnectedness of human beings, nature, and Jubata. In its encounter with the Catholic faith, the dance was incorporated into the Eucharistic celebration as an offertory dance through symbolic reinterpretation grounded in the principles of inculturation articulated by the Second Vatican Council. This research employs a hermeneutical approach using participant observation, in-depth interviews, and documentary study, analyzed through thematic analysis. The findings indicate that Ka’Bawakng dance is not treated as a merely decorative liturgical element, but is understood as a language of prayer engaging the body, cultural memory, and the spirituality of the faithful. This integration deepens liturgical participation, strengthens the religious–cultural identity of the Dayak Kanayatn community, and creates a constructive space for dialogue between ancestral traditions and Christian faith. Nevertheless, sustaining the inculturation of Ka’Bawakng dance requires ongoing pastoral accompaniment to ensure fidelity to Church liturgical norms while respecting local cultural values.

Rima Anggraini; Yuyun Amalia Caniago; Risdah Mahyuni; Widya Rahayu; Ros Mardiah +4 more

Jurnal Pendidikan Kimia, Fisika dan Biologi 2026 Asosiasi Riset Ilmu Pendidikan Indonesia

Antibiotics are one of the main pillars in the treatment of bacterial infections and have contributed significantly to increasing human life expectancy. However, long-term use of antibiotics has serious consequences for the balance of the body's microbiome, especially the gut microbiome which plays an important role in maintaining homeostasis through the regulation of the immune system, metabolism, and protection against pathogens. This literature review aims to comprehensively analyze the impact of long-term antibiotic use on the structure, diversity, and function of the human microbiome. The scientific articles reviewed were obtained from PubMed, Scopus, ScienceDirect, and Google Scholar databases, including empirical research, systematic review, and meta-analysis published in the last ten years. The results showed that prolonged exposure to antibiotics consistently decreased microbiota diversity, altered the composition of bacterial communities, and triggered dysbiosis, which is often persistent even when therapy is stopped. Dysbiosis is associated with impaired immune system function, increased systemic inflammation, risk of allergic and metabolic diseases, and potential disorders on the intestinal-brain axis. This impact is more pronounced in vulnerable groups such as neonates and children, especially when exposure occurs during a critical period of development. In conclusion, long-term antibiotic use has broad systemic implications, so a more rational, prudent, and sustainable use strategy is needed to maintain the health of the human microbiome.

Faiq Ghosan Alghoniy Albin; Rahmadsyah Rahmadsyah

Inovasi Kesehatan Global 2026 Lembaga Pengembangan Kinerja Dosen

Forensic entomology is a branch of forensic science that utilizes insects and other arthropods as biological indicators in death investigations. This discipline plays a crucial role, particularly in cases of advanced decomposition, where conventional forensic methods often face limitations. One of the key contributions of forensic entomology is estimating the post-mortem interval (IPM), or time since death, which can assist investigators in reconstructing the chronology of events. Furthermore, entomological analysis can provide information regarding the location of death, possible movement of the body, and environmental conditions surrounding the crime scene. Common approaches include analyzing insect succession patterns that appear according to the stages of decomposition of the body and determining the age of larvae based on their developmental stage and growth rate. Environmental factors, particularly temperature, humidity, and microhabitat conditions, significantly influence insect development and therefore must be carefully considered in the analysis. This literature review aims to discuss the basic concepts, functions, and role of forensic entomology in law enforcement. Furthermore, this review emphasizes the importance of accurate insect species identification to improve the validity and reliability of the resulting time-of-death estimates.

Adhe Fadli Farhan; Eki Darmawan; Kustiawan Kustiawan; Yudhanto Satyagraha Adiputra; Erta Kurnia Sapitri +2 more

Desentralisasi : Jurnal Hukum, Kebijakan Publik, dan Pemerintahan 2026 Asosiasi Peneliti dan Pengajar Ilmu Hukum Indonesia

This study evaluates the effectiveness of the SOSEK MALINDO (Malaysian-Indonesian Socio-Economic) regional collaboration program in addressing human trafficking, coordinated by the Regional Border Management Agency (BPPD) of the Riau Islands Province (Kepri). The Riau Islands Province, which borders Malaysia and Singapore, is a strategic entry point vulnerable to transnational crimes, including human trafficking. The main factors driving the people of Kepri to choose illegal routes to become Indonesian Migrant Workers (TKI) to Malaysia are economic pressure, limited job opportunities, attractive promises from brokers (tekong), complex and expensive official bureaucracy, and a lack of accurate information about official procedures. This situation is exploited by human trafficking networks through hidden routes, illegal ports, and methods of illegal labor and sexual exploitation. Although SOSEK MALINDO aims to improve the socio-economic welfare of communities in border areas and indirectly functions to reduce vulnerability to human trafficking, this program does not specifically make human trafficking its main focus. The BPPD plays a very important role as a liaison in cooperation with the Indonesian National Police, Immigration, and BP3MI for prevention and supervision. However, the BPPD faces challenges such as limited funding, overlapping authority between institutions, and a lack of accurate data on human trafficking. Strategic recommendations include making human trafficking a primary focus of the SOSEK MALINDO forum agenda, establishing a dedicated cross-border human trafficking task force, strengthening the BPPD's role in coordination and information gathering, and involving local communities, NGOs, and international organizations in mitigation efforts.

ariyanti, lilik; Priscilla Rosita Putri Nurmasari; Almas Awanis

Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana (JUFDIKES) 2026 Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Gaya hidup remaja masa kini sangat erat kaitannya dengan penggunaan smartphone, di mana hampir seluruh remaja telah memiliki smartphone pribadi. Penggunaan smartphone yang tidak terkontrol berisiko menimbulkan kecanduan yang dapat berdampak negatif terhadap kualitas hidup remaja. Kondisi ini berdampak pada status gizi yang tidak normal pada remaja, diantaranya kekurangan berat badan (underweight) maupun kelebihan berat badan (overweight). Tujuan penelitian ini adalah mengetahui hubungan kecanduan smartphone terhadap Indeks Massa Tubuh. Desain penelitian ini cross sectional dengan sampel 242 remaja usia 15-18 tahun dan menggunaan teknik purposive sampling. Instrumen penelitian yang digunakan adalah Smartphone Addiction Scale-Short Version yang sudah diuji validitas dan reliabilitasnya dengan nilai cut off point kuesioner untuk laki-laki >31 dinyatakan kecanduan smartphone sedangkan untuk perempuan >33 dinyatakan kecanduan smartphone, selain itu dilakukan pengukuran IMT berdasarkan berat badan dan tinggi badan. Analisa data yang dilakukan menggunakan uji statistik Chi-Square dengan uji alternatif Fisher Extract melalui SPSS versi 25. Hasil yang diperoleh yaitu p-value (0,014 < 0,05) yang menunjukan terdapat hubungan antara kecanduan smartphone terhadap Indeks Massa Tubuh (IMT).

Samia Wildana A; Nurifah Nurifah; Sri Hastuti Andayani

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

Nephrotic syndrome (NS) is a kidney disorder characterized by massive proteinuria, hypoalbuminemia, edema, and hypercholesterolemia, most commonly occurring in children. This disease can be caused by various conditions, such as minimal change disease, FSGS, or lupus nephritis. This case report discusses a 16-year-old boy who experienced nephrotic syndrome with symptoms of swelling throughout his body, accompanied by decreased appetite and a productive cough. The patient presented with complaints of swelling throughout his body that began 7 days after hospitalization and was accompanied by coughing and shortness of breath. A physical examination revealed massive edema, abdominal hypertympany, and shifting dullness. Laboratory tests revealed proteinuria, hypoalbuminemia, and decreased serum albumin. Other supporting tests confirmed nephrotic syndrome. The patient received medication therapy including diuretics, corticosteroids in the form of methylprednisolone, and albumin. Nephrotic syndrome in children can develop gradually and requires management that includes steroids, diuretics, and close monitoring of kidney function and electrolytes. Early detection and appropriate treatment can help improve the patient's prognosis.

Ni Kadek Lidia Ayu Aristina; I Gede Made Suradnyana; Ni Made Sukma Sanjiwani

Jurnal Riset Ilmu Farmasi dan Kesehatan 2026 Asosiasi Riset Ilmu Kesehatan Indonesia

Skin is the body's outermost organ, enveloping all parts of the human body. When the water content in the stratum corneum (SC) drops below 10%, the skin can become scaly, rough, and dry. Honey possesses humectant, emollient, and antioxidant properties, making it an effective moisturizer. The humectant properties of honey stem from its high sugar content, particularly glucose and fructose. These  sugars form hydrogen bonds with water, helping to retain moisture in the skin and thus providing a hydrating effect. Additionally, honey contains vitamin C, alpha hydroxy acids, and flavonoids, which contribute to the elasticity and firmness of the skin. Therefore, it is important to conduct a narrative review on the use of honey as a moisturizer in topical preparations, which can serve as a reference for future research. The literature search for this review was conducted using databases such as Google Scholar, Garuda Journal, MDPI, ResearchGate, and Publish or Perish, employing specific inclusion and exclusion criteria. The findings concluded that honey can be used as a moisturizer in various dosage forms, including body scrubs, anti-aging and moisturizing creams, serums, peel-off gel masks, lip moisturizers, and lip scrubs. The concentration of honey used in these formulations depends on the dosage form, its intended function in the formula (whether as an active substance, humectant, or emollient), and the comparison of honey concentration with other ingredients.

Muhammad Zahran Saputra; Ardi Mustakim

Inovasi Kesehatan Global 2026 Lembaga Pengembangan Kinerja Dosen

Inflammation is a biological response that occurs as a defense mechanism of the body against tissue damage, infection, or exposure to harmful stimuli. Excessive or prolonged inflammation can lead to various chronic diseases and negatively affect overall health. Natural compounds derived from medicinal plants have gained attention as alternative anti-inflammatory agents due to their relatively lower side effects compared to synthetic drugs. Jatropha curcas is a plant traditionally used in herbal medicine and is known to contain various bioactive compounds. This study aims to examine the effect of Jatropha curcas leaf extract on inflammatory responses. The research method used was an experimental laboratory approach with extract preparation through maceration techniques. The anti-inflammatory effect was evaluated based on changes in inflammatory indicators observed during the treatment process. The results showed that Jatropha curcas leaf extract demonstrated potential anti-inflammatory activity, which was indicated by a reduction in inflammatory signs. The presence of secondary metabolites such as flavonoids, tannins, and saponins is suspected to contribute to this effect. These findings suggest that Jatropha curcas leaf extract has promising potential as a natural anti-inflammatory agent. Further research is recommended to explore dosage optimization and toxicity levels for safe therapeutic use.  

Jacqualyne Gavrilla Kumayas; Fransisca Iriani Roesmala Dewi

International Journal of Education and Literature 2026 Lembaga Pengembangan Kinerja Dosen

This study aims to determine the role of social comparison and body image on appearance anxiety in adolescent girls. Social pressure and media exposure with ideal beauty standards make adolescent girls vulnerable to engaging in social comparison and developing a negative body image, which triggers appearance anxiety. This study used a quantitative approach with a correlational design involving 107 adolescent girls aged 18–24 years through convenience sampling. Data were collected using a Google Forms questionnaire consisting of three instruments: the Iowa-Netherlands Comparison Orientation Measure, the Multidimensional Body-Self Relations Questionnaire, and the Social Appearance Anxiety Scale. Data analysis used Spearman correlation and multiple linear regression. The results showed that social comparison has a significant positive relationship with appearance anxiety (r = 0.544, p < 0.001), and negative body image is related to increasing appearance anxiety. The higher the tendency to engage in social comparison and the more negative the body image, the higher the appearance anxiety experienced. The findings emphasize the importance of understanding the psychological dynamics of appearance evaluation and strategies to strengthen positive body image in adolescent girls.

Cintana Balkis Habibah; Aditya, Tiara Dewinta; Assyifa Azzahra; Triana Srisantyorini; Ayunda Larasati Sekarputri +1 more

Karakter : Jurnal Riset Ilmu Pendidikan Islam 2026 Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

Thaharah represents a core principle within Islamic teachings, encompasses both bodily cleanliness and spiritual sanctity, and functions as an essential requirement for the proper observance of acts of worship, including prayer, tawaf, and the recitation of the Qur’an. This concept extends beyond ritual practice, reflecting a manifestation of faith that encourages Muslims to maintain personal hygiene, environmental cleanliness, and spiritual closeness to Allah SWT. This study aims to explore and critically examine the concept of thaharah in a comprehensive manner, clarify its role within Islamic religious practices, and assess its relevance in fostering clean lifestyle behaviors and appropriate worship practices in accordance with Islamic legal principles in contemporary society. Conceptually, thaharah is divided into two main forms: purification from ritual impurity (hadas) through ablution (wudu), ritual bathing (ghusl), or dry purification (tayammum), and purification from physical impurities (najis) by cleansing the body, clothing, and surrounding environment. The normative foundation of thaharah is reinforced by textual evidence, including Surah Al-Ma’idah verse 6 and prophetic traditions that emphasize cleanliness as an integral part of faith. Thus, thaharah offers a holistic perspective on cleanliness that integrates both worldly and spiritual dimensions of Muslim life.  

Yoga Cahya Mahardika; Pungky Slamet Wisnu Kusuma; Tatang Sopandi

Habitat: Jurnal ilmiah ilmu Hewani dan Peternakan 2026 Asosiasi Riset Ilmu Tanaman Dan Hewani Indonesia

Beef demand in Indonesia continues to increase, particularly during religious holidays. Bali cattle, one of the main sources of beef, face a serious threat from Jembrana disease, a viral infection that compromises the immune system and causes significant economic losses. This study aimed to determine the correlation between spleen weight, body temperature, and cycle threshold (Ct) values in Bali cattle following Jembrana virus inoculation. A correlational method was applied to eight female Bali cattle injected with Jembrana virus inoculum. Physiological changes in body temperature were monitored, followed by necropsy to assess spleen weight. In addition, Real-Time Polymerase Chain Reaction (RT-PCR) was performed before and after inoculation to detect viral presence and determine Ct values. Data were analyzed using SPSS with Pearson correlation tests. The results revealed a very strong positive correlation between spleen weight and body temperature, while a very strong negative correlation was observed between spleen weight and Ct values. These findings indicate that Jembrana virus inoculation leads to increased body temperature and splenic enlargement in Bali cattle, accompanied by a decrease in Ct values, reflecting higher viral loads. Therefore, the administration of antipyretics, anti-inflammatory drugs, analgesics, vitamins, and antibiotics prior to vaccination is recommended to reduce the risk of hyperthermia, splenic swelling, decreased Ct values, and secondary infections.

Astrina Rosaria Indah

Jurnal Tifa Medika 2026 Fakultas Kedokteran Universitas Cenderawasih Jayapura

Malaria remains a major public health problem in Papua, Indonesia, with a high incidence rate and significant hematological complications. One of the main impacts of malaria infection is anemia caused by a decrease in hemoglobin levels. This study aimed to analyze the relationship between hemoglobin levels and malaria parasite species among patients at Sentani Health Center, Jayapura Regency. This was an analytical study with a cross-sectional approach. A total of 50 malaria-positive patients confirmed by microscopic examination were included as samples. Data collected included gender, parasite species, nutritional status, hemoglobin level, and parasite count, analyzed using the Chi-Square test with a 95% confidence level (α=0.05). The results showed that most respondents were male (54%) and predominantly infected by Plasmodium falciparum (66%). The majority had normal nutritional status (40%), and the distribution between normal and abnormal hemoglobin levels was equal (50% each). Statistical analysis revealed a significant association between body mass index and hemoglobin level (p=0.03), but no significant relationship between parasite species and hemoglobin level (p=0.145). These findings indicate that nutritional status plays a more dominant role in determining hemoglobin levels than parasite species variation. In conclusion, anemia among malaria patients in endemic regions is influenced not only by the infecting Plasmodium species but also by individual nutritional factors. Integrated interventions focusing on nutritional improvement and malaria control are essential to reduce anemia risk in endemic areas such as Papua. Malaria remains a major public health problem in Papua, Indonesia, with a high incidence rate and significant hematological complications. One of the main impacts of malaria infection is anemia caused by a decrease in hemoglobin levels. This study aimed to analyze the relationship between hemoglobin levels and malaria parasite species among patients at Sentani Health Center, Jayapura Regency. This was an analytical study with a cross-sectional approach. A total of 50 malaria-positive patients confirmed by microscopic examination were included as samples. Data collected included gender, parasite species, nutritional status, hemoglobin level, and parasite count, analyzed using the Chi-Square test with a 95% confidence level (α=0.05). The results showed that most respondents were male (54%) and predominantly infected by Plasmodium falciparum (66%). The majority had normal nutritional status (40%), and the distribution between normal and abnormal hemoglobin levels was equal (50% each). Statistical analysis revealed a significant association between body mass index and hemoglobin level (p=0.03), but no significant relationship between parasite species and hemoglobin level (p=0.145). These findings indicate that nutritional status plays a more dominant role in determining hemoglobin levels than parasite species variation. In conclusion, anemia among malaria patients in endemic regions is influenced not only by the infecting Plasmodium species but also by individual nutritional factors. Integrated interventions focusing on nutritional improvement and malaria control are essential to reduce anemia risk in endemic areas such as Papua.

Nuris Dwi Setiawan; Hendri Rasminto; Muhamad Sidik

Information System Analysis, Design and Development 2026 Asosiasi Pengelola Jurnal Informatika dan Komputer Indonesia

Digital transformation (DT) has become a critical component for organizations aiming to enhance their operational efficiency, innovation, and competitiveness. However, many organizations struggle to achieve successful digital transformation due to the misalignment between their Enterprise Information Systems (EIS) and organizational strategic goals. This research seeks to design and validate a model for aligning EIS with digital transformation strategies to improve organizational effectiveness. By adopting the Design Science Research (DSR) approach, this study develops a practical model that integrates strategic planning, process management methodologies, and emerging technologies to facilitate alignment between IT and business strategies. The research includes key steps such as requirement analysis, artifact design, expert validation, and case study evaluation to ensure the model's robustness and applicability across different organizational contexts. Findings indicate that the proposed model significantly improves strategic-system alignment, enhances decision-making consistency, and facilitates better integration between business and IT units. The model also addresses common challenges such as resistance to change, skill gaps, and misalignment, fostering a supportive culture for digital transformation. In comparison to existing descriptive frameworks, the proposed model is more structured, adaptable, and actionable, providing organizations with a clear framework to guide their digital transformation efforts. This research contributes to the growing body of knowledge on EIS alignment and offers practical insights for organizations seeking to achieve successful digital transformation. Future research could explore the model's application in various organizational settings and examine its impact on long-term organizational growth and innovation.

Intan Wuri Handayani; Lusiana Lusiana; Hadi Firmansyah

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, life-threatening mucocutaneous reactions characterized by extensive epidermal necrolysis and mucosal involvement. The entities represent a clinical continuum distinguished by the extent of epidermal detachment (SJS <10% body surface area [BSA], SJS/TEN overlap 10–30%, TEN >30%). Most cases are drug-induced, making early culprit-drug withdrawal and structured supportive care the cornerstones of management. Immunopathogenesis is primarily mediated by drug-specific cytotoxic T cells and NK cells through granulysin, Fas–Fas ligand, and perforin/granzyme pathways, with emerging roles of necroptosis and candidate biomarkers such as RIP3 and galectin-7. Diagnosis relies on timely recognition of the characteristic painful erythematous/targetoid lesions, Nikolsky/Asboe–Hansen signs, multi-site mucositis, accurate BSA assessment, and early severity scoring (e.g., SCORTEN) to guide referral and monitoring. Systemic immunomodulators (corticosteroids, cyclosporine, IVIg, anti-TNF agents) have variable evidence; thus, individualized selection and early multidisciplinary care particularly ophthalmologic involvement are essential to reduce acute mortality and long-term sequelae.

Olivia Charissa; Santoso, Alexander Halim; Wijaya, Bryan Anna

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

The increasing prevalence of metabolic syndrome and chronic kidney disease underscores the need for simple, low-cost, and community-applicable screening indicators. This study aimed to evaluate the association between basic anthropometric parameters and blood pressure, metabolic indicators, and renal function among adults in the Badui Luar community. A cross-sectional design was employed involving 41 participants who underwent anthropometric assessment, biochemical measurements, and blood pressure evaluation. Pearson correlation analysis was used to examine linear associations between variables. The results demonstrated that neck circumference exhibited significant correlations with dyslipidemia components, including LDL (r = 0.377), TC/HDL ratio (r = 0.516), and HDL (r = –0.433), indicating cervical adiposity as a strong marker of atherogenic risk. Calf circumference showed protective correlations with fasting glucose (r = –0.352) and eGFR (r = 0.322), suggesting the metabolic relevance of peripheral muscle mass in glycemic regulation and renal status. Body mass index showed a weak correlation with systolic blood pressure (r = 0.149), whereas waist and hip circumferences exhibited mild, clinically insignificant correlations with triglycerides and total cholesterol. Overall, these findings highlight that simple anthropometric measures—particularly neck and calf circumference—may serve as early indicators of cardiometabolic and renal risk in community-based screening. Further longitudinal studies with larger and more heterogeneous populations are required to validate these associations and determine the predictive power of anthropometric indicators.