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Fadhilatul Amaliya; Anindya Rahma Fathiya; Tiara Jelita Andalusianti Roozan; Isna Nurul Hasanah; Dewi Sekar Pembayun

Jurnal Riset Rumpun Ilmu Sosial, Politik dan Humaniora 2026 Pusat Riset dan Inovasi Nasional

The Lapindo Brantas case is the largest environmental disaster in Indonesia, causing significant environmental damage and widespread economic and social impacts on the surrounding community. This incident sparked debate about corporate legal responsibility for the damage that occurred. This study aims to thoroughly evaluate the responsibility of the Lapindo Brantas corporation using the responsibility theory approach and Law Number 32 of 2009 concerning Environmental Protection and Management. The methods used are normative with case studies and legislative analysis to understand the mechanism of corporate legal responsibility in the context of environmental disasters. The findings of this study indicate that corporations can be held criminally liable for environmental damage, and in the case of Lapindo Brantas, the company bears legal responsibility in accordance with the principle of strict liability as stipulated in Law Number 32 of 2009. This study emphasizes the urgency of applying the principle of corporate responsibility as an important part of environmental law enforcement in Indonesia.

Ni Nyoman Anandia Vidya Paramita; Irma Rahmayani; Ni Made Widya Pradnya Dewani; Agastya Cahya Ariadi; Ida Bagus Gde Ari Janar Dana +1 more

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

Blood sugar regulation problems such as diabetes are increasing, so sustainable management is needed. Kersen leaves (Muntingia calabura L.) are tropical plants that have potential as traditional blood sugar management through the content of phytochemical compounds contained therein. This article aims to review the potential of kersen leaves in blood sugar management and its implications in the wellness tourism approach. The method used is a literature review of scientific literature, especially the last five years related to the phytochemical content and antihyperglycemic activity of kersen leaves, as well as their implications in wellness tourism. The results of the literature review through in vivo and in vivo approaches show that kersen leaves contain potential phytochemical compounds such as flavonoids, phenols, tannins, alkaloids, and saponins that are able to regulate blood sugar by preventing the oxidation process of important molecules by free radicals, suppressing oxidative stress, inhibiting carbohydrate enzymes, increasing insulin production, and suppressing the glycogenolysis process. In the context of wellness tourism, kersen leaves as a herbal plant can be used as a healthy drink and have the potential to be studied further in the development of wellness tourism, especially related to herbal medicine.

Satria Efandi; Wiwik Indrayeni

Jurnal Riset Rumpun Ilmu Bahasa 2026 Pusat riset dan Inovasi Nasional

Workplace microaggressions represent subtle and ambiguous forms of interpersonal mistreatment that are frequently normalized in organizational interactions, yet may generate significant psychological consequences for employees. While research in industrial and organizational psychology has extensively examined related constructs such as workplace incivility and ostracism, the linguistic mechanisms through which microaggressions operate remain underexplored. This study aims to systematically review Indonesian-language journal articles published between 2015 and 2025 that address workplace microaggressions and related phenomena, by conceptualizing microaggressions as speech acts. Using a systematic literature review approach guided by the PRISMA 2020 framework, relevant peer-reviewed articles were identified, screened, and analyzed through thematic synthesis. The review focuses on three main aspects: linguistic forms of microaggressions, contexts in which they emerge, and their psychological consequences in formal organizational settings, including companies and educational institutions. The findings indicate that workplace microaggressions are predominantly realized through indirect and ambiguous communicative practices, such as dismissive remarks, stereotypical humor, and interactional exclusion, often occurring within hierarchical relationships and formal work situations. These communicative acts are consistently associated with negative psychological outcomes, including stress, emotional exhaustion, reduced wellbeing, and withdrawal-related work attitudes. By integrating industrial-organizational psychology with linguistic-pragmatic perspectives, this review highlights language as a central mechanism through which microaggressions produce psychological harm at work. The study contributes a conceptual synthesis that underscores the importance of addressing everyday communicative practices in organizational interventions aimed at fostering psychological safety and employee wellbeing.

Pramandyah Fitah Kusuma; Rodhiyah

Jurnal Mutiara Ilmu Akuntansi (JUMIA) 2026 Pusat Riset dan Inovasi Nasional

Micro, Small, and Medium Enterprises (MSMEs) face significant challenges in financial management, particularly related to transparency and reliability of transaction tracking, which hinders their access to formal financing. This study aims to synthesize scientific evidence regarding the application of blockchain technology in improving the tracking and transparency of financial transactions in MSMEs. Using a Systematic Literature Review (SLR) or Wide Research approach with the PICOS framework, ten (10) relevant primary studies (original research papers) were identified, selected, and analyzed. The synthesis results show that blockchain significantly improves transparency, data security, and cost efficiency in tracking MSME transactions, and has great potential in increasing access to financing through a more credible credit scoring system. However, the main challenges lie in the high initial implementation costs and the need for digital literacy. This study provides a clear roadmap for researchers, policymakers, and practitioners to optimize the adoption of blockchain technology in the MSME sector.

Nadira Zahra Faisal

Doktrin: Jurnal Dunia Ilmu Hukum dan Politik 2026 International Forum of Researchers and Lecturers

This study aims to analyze the legal status of jointly managed social media accounts within the framework of marital property in Indonesia. The growth of the digital creative economy has transformed social media accounts into productive assets with economic value, yet Indonesian civil law has not provided legal certainty regarding their ownership status following divorce or death. The research method employed is normative legal research with a comparative legal approach. The results indicate a regulatory void in Law Number 1 of 1974, which remains oriented toward physical objects, while digital accounts are often regarded as personal rights tied to the registered individual. Conversely, digital regulations in the European Union, through the General Data Protection Regulation (GDPR) and the concept of digital estate, have begun to accommodate the continuity of access and management of digital assets for relevant parties. The discussion emphasizes the need for a redefinition of assets in Indonesian family law that synchronizes privacy rights with economic rights. In conclusion, productive social media accounts should be qualified as marital property through progressive interpretation or prenuptial agreements. This study recommends the synchronization of personal data protection regulations and marriage law to ensure distributive justice for couples in the digital economy era.

Dwi Lestari, Indah; Aulia Ramdini, Dwi; Yuliyanda Pardilawati, Citra; Dwi Rahayu , Ihsanti

Jurnal Mahasiswa Ilmu Kesehatan 2026 STIKes Ibnu Sina Ajibarang

Penyakit Paru Obstruktif Kronik (PPOK) merupakan penyakit progresif yang ditandai oleh hambatan aliran udara yang tidak sepenuhnya reversibel, serta memiliki tingkat kepatuhan pengobatan yang rendah. Salah satu strategi yang dapat dilakukan untuk meningkatkan kepatuhan adalah melalui konseling oleh apoteker. Tujuan dari tinjauan literatur ini adalah untuk mengevaluasi pengaruh konseling apoteker terhadap tingkat kepatuhan pengobatan pada pasien PPOK. Pencarian data dilakukan melalui beberapa basis data, yaitu Google Scholar, Springer, ScienceDirect, dan PubMed dengan topik yang relevan. Hasil tinjauan menunjukkan bahwa konseling apoteker secara signifikan meningkatkan pemahaman pasien mengenai penyakit PPOK, manajemen eksaserbasi, dan teknik penggunaan inhaler yang benar. Selain itu, konseling juga berperan dalam mengurangi kecemasan, meningkatkan kepercayaan diri, efikasi diri, dan pengelolaan terapi yang lebih baik. Dengan demikian, implementasi konseling apoteker dalam praktik klinis sangat dianjurkan sebagai upaya meningkatkan kepatuhan pengobatan dan memperbaiki kualitas hidup pasien PPOK.

Nadia Putri Sabrina; Sri Trisnaningsih

Prosiding Seminar Nasional Ilmu Ekonomi dan Akuntansi 2026 Asosiasi Riset Ekonomi dan Akuntansi Indonesia

The development of e-commerce and digital financial services has changed consumer behavior, particularly among Generation Z. One emerging innovation is the Paylater service, which offers convenience and flexibility in transactions. While providing easy access, the use of Paylater also has the potential to increase consumer behavior and impulsive purchases. This study aims to analyze the role of financial literacy and lifestyle in the use of Paylater services among Generation Z through the Systematic Literature Review (SLR) method. A total of ten scientific articles published in the last five years were analyzed to examine the relationship between financial literacy, lifestyle, and Paylater usage behavior. The results show that financial literacy has an inconsistent influence and tends to act as a controlling factor, while a consumptive and hedonistic lifestyle is the dominant factor driving Paylater use. In addition, behavioral factors such as impulsive purchases and technological convenience also strengthen the tendency to use these services. This study concludes that increasing financial literacy balanced with controlling a consumptive lifestyle is very influential in encouraging the wise and sustainable use of Paylater.

Ayu Lestari; Avo Agnesia

Perspektif Administrasi Publik dan hukum 2026 Asosiasi Peneliti Dan Pengajar Ilmu Sosial Indonesia

Decision-making under uncertainty is a major challenge in management, economics, and public policy, where outcomes cannot be accurately predicted due to limited information and environmental dynamics. This article conducts a systematic literature review of risk and probability approaches to decision-making under uncertainty, focusing on rational theory synthesis (such as expected utility theory, decision tree analysis, and Bayesian decision theory) and behavioral perspectives (prospect theory and heuristics). The review covers reputable literature from the last ten years to the present. The results show that the probabilistic approach provides a strong and adaptive rational framework, but has significant limitations due to cognitive biases such as loss aversion, overconfidence, and ambiguity aversion, which cause deviations from normative rationality. The integration of rational approaches with behavioral elements, through hybrid models, has proven to be more comprehensive and realistic for dealing with true uncertainty (Knightian uncertainty). These findings emphasize the need for a multidimensional decision-making paradigm in organizational and policy practices.

Nurtisari Nurtisari; Ni Made Witari Dewi; I Wayan Adnyana

Doktrin: Jurnal Dunia Ilmu Hukum dan Politik 2026 International Forum of Researchers and Lecturers

This research is motivated by the rise of online sales fraud cases on the island of Bali that are detrimental to consumers, the purpose of this research is to analyze it from the aspect of juridical studies and the basis of judges' decisions in deciding cases, this research uses a normative method with a library approach, the results of the study show that online fraud crimes utilize digital technology to manipulate data, here the defendant uses fake transfer evidence as a tool to deceive the store that meets the elements in Article 378 of the Criminal Code, namely the intention to benefit oneself unlawfully, and Article 35 of the ITE Law concerning manipulation of electronic information with the aim of making the data considered authentic, the basis for the judge's consideration to pass a verdict because the existence of photos of transfer evidence and the victim's account balance is sufficient to convince the judge that the defendant is guilty. Legal protection for victims of online fraud has been regulated in the Consumer Protection Law, the ITE Law and government regulations related to electronic transactions, but to strengthen preventive and systemic efforts, public education and increased capacity of law enforcement officers are needed, With the latest regulations such as Law No. 1 of 2024 concerning the second amendment to the ITE Law, Presidential Decree No. Law No. 49 of 2024 concerning the National Strategy for Consumer Protection and Minister of Trade Regulation No. 17 of 2024 concerning the National Action Plan for Consumer Protection have implications for strengthening legal protection for victims of online fraud, which is expected to provide a sense of security in digital transactions.

Putri, Shakira Izzatya; Sayoeti, Muhammad Fitra Wardhana; Damayanti, Ervina; Himayani, Rani

Jurnal Mahasiswa Ilmu Kesehatan 2026 STIKes Ibnu Sina Ajibarang

Perkembangan teknologi informasi dan komunikasi telah mendorong transformasi pelayanan kesehatan, termasuk di bidang kefarmasian. Salah satu inovasi yang berkembang adalah telefarmasi, yaitu pelayanan kefarmasian jarak jauh yang memanfaatkan teknologi digital untuk menjembatani interaksi antara apoteker dan pasien. Studi ini bertujuan untuk mengkaji persepsi apoteker terhadap implementasi telefarmasi melalui pendekatan tinjauan literatur. Metode yang digunakan adalah tinjauan literatur sistematis terhadap 10 artikel yang diperoleh dari basis data ilmiah seperti PubMed, Google Scholar, dan ScienceDirect dalam lima tahun terakhir. Hasil menunjukkan bahwa mayoritas apoteker memiliki persepsi positif terhadap telefarmasi, terutama dalam aspek efisiensi waktu dan biaya, peningkatan akses dan kepatuhan pasien, serta solusi atas kekurangan tenaga apoteker. Namun, ditemukan pula persepsi negatif seperti beban kerja yang meningkat, risiko kesalahan akibat keterbatasan kontak fisik, dan kendala teknis. Temuan ini menegaskan perlunya dukungan infrastruktur, pelatihan tenaga kesehatan, serta literasi digital pasien untuk memastikan keberhasilan implementasi telefarmasi secara berkelanjutan.

Ulfa Fatimah; Alex Prayoga Sidabutar; Jihan Aisyah Ramahdania; Dorlince O Hutapea; Parlaungan G Siahaan +1 more

Jurnal Riset Rumpun Ilmu Sosial, Politik dan Humaniora 2026 Pusat Riset dan Inovasi Nasional

The crime of receiving stolen goods, as regulated in Article 480 of the Criminal Code (KUHP), is an offence that plays a crucial role in the continuation of the principal crime, particularly theft. Receivers provide a market for stolen goods, thereby indirectly encouraging perpetrators to continue their actions. This paper investigates how Article 480 of the KUHP in judicial practice, with a focus on proving the element of ‘knowing or reasonably suspecting’ that the goods purchased were obtained through criminal activity. This study uses a qualitative method with a case study approach through direct observation of a trial at the M. District Court. The observations show that the panel of judges successfully proved the defendant's guilt as a fence through a series of trial facts, such as the unreasonable purchase price, consistent testimony from the perpetrator of the theft, and the defendant's own admission that he had been suspicious. The judge's decision, which was lighter than the prosecutor's demands, also reflected considerations of substantive justice and humanity in addition to legal certainty. This study concludes that the effective enforcement of Article 480 of the Criminal Code in court plays an important role in breaking the chain of crime and providing a deterrent effect not only for the main perpetrators but also for those who participate in enjoying the proceeds of crime.  

Tri Restu Handayani

Journal of Educational Innovation and Public Health 2026 Pusat Riset dan Inovasi Nasional

Low back pain is one of the most common complaints experienced by pregnant women, particularly in the third trimester, as a result of various physiological, hormonal, and biomechanical changes that occur during pregnancy. Changes in posture, weight gain, and shifts in the center of gravity contribute to the development of this condition. This study aims to examine various non-pharmacological interventions that can be used to reduce low back pain in pregnant women and to analyze the role of midwives in implementing these interventions in midwifery practice. The method employed is a narrative literature review synthesizing ten verified and relevant studies, particularly those discussing prenatal yoga and pregnancy exercise as forms of non-pharmacological intervention. The results indicate that the implementation of prenatal yoga and pregnancy exercise is effective in reducing the intensity of low back pain, improving muscle flexibility and strength, and providing physical and psychological relaxation for pregnant women. In addition, these interventions contribute to increased comfort and improved quality of life during pregnancy. The findings of this study support the importance of evidence-based midwifery practice and highlight the active role of midwives in providing education, assistance, and empowerment for pregnant women through the application of safe and effective non-pharmacological interventions.

Triyanto Agung Praptono Wibowo

Pemuliaan Keadilan 2026 Asosiasi Penelitian dan Pengajar Ilmu Hukum Indonesia

The increasing number of malpractice cases in Indonesia, particularly those related to misdiagnosis by medical practitioners, highlights the urgency of law enforcement in the health sector. This study aims to analyze the legal provisions and forms of physician liability for misdiagnosis resulting in patient death. The research employs a normative juridical approach with a library research method, using primary legal materials such as Law Number 17 of 2023 on Health, the Criminal Code (KUHP), and the Civil Code (KUHPerdata), as well as secondary legal materials including literature and legal health journals. The findings indicate that misdiagnosis proven to constitute professional negligence (culpa) may give rise to legal liability in three areas—criminal, civil, and administrative. Criminally, Article 440 of Law Number 17 of 2023 stipulates sanctions for medical personnel whose negligence causes serious injury or death (Republic of Indonesia, 2023). Furthermore, hospitals also bear responsibility under the doctrines of vicarious liability and hospital liability for the actions of medical practitioners under their supervision (Balubun, Simanjuntak, & Ginting, 2018). This research implies the need for a balanced legal protection framework between patients’ rights and the professional rights of medical practitioners, as well as the strengthening of medical supervision systems within healthcare institutions.

Nabila Nuraisyah Rizkianti; Trias Mahmudiono

Inovasi Kesehatan Global 2026 Lembaga Pengembangan Kinerja Dosen

The consumption of ultra-processed foods (UPF) has been increasing among various age groups, including children and adults. UPF is generally low in iron content and can interfere with iron bioavailability, thereby increasing the risk of anemia. Additionally, the high calorie content of UPF contributes to the development of degenerative diseases. This study aims to analyze the relationship between UPF consumption, iron intake, and the risk of anemia. The study employs a narrative review method. Literature search was conducted using PubMed, Google Scholar, and Scopus databases, using controlled terms. The results showed that high UPF consumption had a negative impact on iron intake and increased the risk of anemia. Similar effects were found in high fat and sodium consumption. Some studies showed varying results regarding protein intake, fiber, and micronutrients such as sodium and calcium. In general, it can be concluded that excessive UPF consumption negatively impacts the quality of nutrient intake, both macro and micro, and contributes to the occurrence of anemia. These findings highlight the need for public health strategies to limit UPF consumption, particularly among vulnerable populations, as a preventive effort against anemia.

Darmawansyah Darmawansyah; Reflis Reflis; Mustopa Romdhon; Satria Putra Utama

Jurnal Manajemen Bisnis Digital Terkini 2026 Asosiasi Riset Ilmu Manajemen Kewirausahaan dan Bisnis Indonesia

The economic valuation of natural resources (NR) is an important instrument in supporting evidence-based decision-making, particularly in sustainable environmental management. Cost–Benefit Analysis (CBA) serves as a primary approach to assess the economic feasibility of programs or policies by integrating all benefits and costs, including non-market values. This article presents a systematic literature review of studies employing CBA for NR valuation during the period 2010–2024, based on searches in Scopus, Web of Science, ScienceDirect, SpringerLink, Taylor & Francis, and Google Scholar, using stringent selection criteria. The review findings indicate that CBA has been widely applied in forest management, biodiversity conservation, land rehabilitation, water and air pollution control, and ecotourism development, providing a quantitative depiction of economic feasibility through indicators such as Net Present Value (NPV), Benefit–Cost Ratio (BCR), and Internal Rate of Return (IRR). Key challenges were identified in non-market valuation, long-term uncertainty, data limitations, and sensitivity to discount rate assumptions. These findings underscore the importance of integrating environmental valuation methods, conducting comprehensive sensitivity analyses, and adopting multidisciplinary approaches to strengthen the application of CBA in sustainable NR management, while also offering strategic recommendations and directions for future research for policymakers and environmental economics scholars.

Maya Ganda Ratna; Sinta Nurmalasari; Meta Tri Yana; Alvina Christy Maretta; Mariani Mariani +2 more

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

Urinary tract infection (UTI) is a common bacterial infection that requires appropriate antibiotic management to prevent complications and antimicrobial resistance. Ceftriaxone and ciprofloxacin are commonly used antibiotics with different clinical indications in UTI treatment. This literature review aims to compare the role of ceftriaxone and ciprofloxacin in the management of urinary tract infections. A narrative literature review was conducted using articles published within the last ten years from PubMed, ScienceDirect, and Google Scholar databases. The review focuses on clinical effectiveness, resistance patterns, and therapeutic considerations. The findings indicate that ceftriaxone is primarily used in moderate to severe or complicated UTIs, particularly in hospitalized patients, whereas ciprofloxacin is more frequently used in uncomplicated UTIs in outpatient settings. However, increasing bacterial resistance and safety concerns limit the empirical use of ciprofloxacin. These findings emphasize the importance of rational antibiotic selection based on clinical conditions and local resistance patterns.  

Nova Yolandya Sitanggang; La Syarifudin; Nur Aripkah

Jurnal Riset Ilmu Hukum, Sosial dan Politik 2026 Asosiasi Peneliti dan Pengajar Ilmu Hukum Indonesia

The Criminal Procedure Code (KUHAP) regulates three types of decisions that may be rendered by judges in criminal proceedings. A legal issue arises in situations where a defendant is proven guilty lawfully and convincingly, yet the imposition of a criminal punishment would create a conflict between legal certainty and legal justice. Article 54 paragraph (2) of Law Number 1 of 2023 concerning the Criminal Code (KUHP) introduces a new principle known as Rechtelijk Pardon, or what is referred to as a judicial pardon ruling. This provision offers guidelines for sentencing by considering various factors related to justice and humanity. Following the reform of the Criminal Code through the inclusion of this provision, there emerges a need to reform the Criminal Procedure Code as well, specifically by incorporating the judicial pardon decision into Article 191 of KUHAP. This research employs a normative legal research method using primary and secondary data sources. The research approach utilizes statutory and conceptual approaches. The results of the study emphasize the importance of adding the judicial pardon decision to Article 191 of KUHAP so that the reform of criminal law in Indonesia maintains coherence between substantive and procedural legal reforms, thereby creating a criminal justice system that is more just, humane, and responsive to societal needs.

Khusnul Khotimah Rijie; Ardi Mustakim

Inovasi Kesehatan Global 2026 Lembaga Pengembangan Kinerja Dosen

Papaya fruit (Carica papaya L.) is a tropical plant widely consumed as food and known to contain various bioactive metabolites with potential health benefits. The increasing interest in natural products as functional resources highlights the importance of reviewing the chemical characterization and health applications of papaya bioactive compounds. This article aims to systematically review the types of bioactive metabolites found in papaya fruit, the chemical characterization methods applied, and their potential applications in the health sector. This review was conducted through a literature study of relevant scientific articles, focusing on metabolite identification and biological activity evaluation. The results indicate that papaya fruit contains diverse bioactive metabolites, including flavonoids, phenolic compounds, alkaloids, saponins, terpenoids, and proteolytic enzymes. These compounds are commonly characterized using chromatographic and spectroscopic techniques. Several studies have reported that papaya bioactive metabolites exhibit biological activities such as antioxidant, antimicrobial, anti-inflammatory, and antidiabetic effects. This review suggests that papaya fruit has promising potential as a functional natural resource for health and pharmaceutical applications.

Asika Zahrah; Siti Nurharisha; Melisa Febrianti Sofyan; Rismawati Rismawati

RISOMA : Jurnal Riset Sosial Humaniora dan Pendidikan 2026 Asosiasi Ilmuwan Pendidikan, Sosial, dan Humaniora Indonesia

Reading ability is a basic skill that plays a crucial role in the success of students' learning process. However, various studies indicate that the reading ability of junior high school students remains low. This study aims to analyze the reading ability of students at the UPT SMP Negeri 2 Mappakasunggu using Alfred Schutz's social phenomenology perspective. The research approach used was qualitative with descriptive methods. Data collection techniques included in-depth interviews, observation, and documentation of students and teachers. The results indicate that students' low reading ability is not solely caused by cognitive factors but is also influenced by subjective meanings formed through students' social experiences. The lack of a literacy culture in the family and school environment results in reading not being perceived as an important or enjoyable activity. Furthermore, the dominant use of gadgets for entertainment creates habits that reduce students' interest and concentration in reading texts. From Alfred Schutz's social phenomenology perspective, these conditions are related to students' lifeworlds and stock of knowledge, which shape their perspectives and actions toward reading. This study concludes that improving students' reading ability requires a comprehensive approach, taking into account experiences, social interactions, and the formation of meaning in reading in students' daily lives.

Intan Wuri Handayani; Lusiana Lusiana; Hadi Firmansyah

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, life-threatening mucocutaneous reactions characterized by extensive epidermal necrolysis and mucosal involvement. The entities represent a clinical continuum distinguished by the extent of epidermal detachment (SJS <10% body surface area [BSA], SJS/TEN overlap 10–30%, TEN >30%). Most cases are drug-induced, making early culprit-drug withdrawal and structured supportive care the cornerstones of management. Immunopathogenesis is primarily mediated by drug-specific cytotoxic T cells and NK cells through granulysin, Fas–Fas ligand, and perforin/granzyme pathways, with emerging roles of necroptosis and candidate biomarkers such as RIP3 and galectin-7. Diagnosis relies on timely recognition of the characteristic painful erythematous/targetoid lesions, Nikolsky/Asboe–Hansen signs, multi-site mucositis, accurate BSA assessment, and early severity scoring (e.g., SCORTEN) to guide referral and monitoring. Systemic immunomodulators (corticosteroids, cyclosporine, IVIg, anti-TNF agents) have variable evidence; thus, individualized selection and early multidisciplinary care particularly ophthalmologic involvement are essential to reduce acute mortality and long-term sequelae.