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The purpose of this study was to determine the effect of the Talking Stick Learning Model on Student Learning Activity in the Subject of Christian Religious Education and Character Education for class VIII at SMP Negeri 1 Balige, Toba Regency in the 2024/2025 Academic Year. The research hypothesis is: "there is an effect of the Talking Stick Learning Model on Student Learning Activity in the Subject of Christian Religious Education and Character Education for class VIII at SMP Negeri 1 Balige, Toba Regency in the 2024/2025 Academic Year". The population was all students of class VIII of SMP Negeri 1 Balige, Toba Regency in the 2024/2025 Academic Year who were Protestant Christians totaling 173 people. The research sample was determined using a purposive sampling technique, namely 30 students of class VIII B. This research method uses a quantitative research method with a pre-experimental design type in the form of "one shot case study". The instrument used in this study was a questionnaire item for variable Y totaling 18 items. Based on the experiments that have been carried out, the results obtained before treatment produced an average of 48.10 and after treatment 57.53. The research data for the questionnaire were analyzed using the One-Shot Case Study t-test formula. From the calculation results, the t-value = 3.599> t-table (α = 5%) = 2.042 was obtained. The t-value is in the area of ​​the H0 rejection curve and Ha acceptance. Thus, it can be concluded that with the difference between before and after treatment and t-value> t-table, the research hypothesis is accepted, namely that there is an influence of the Talking Stick Learning Model on Student Learning Activity in Christian Religious Education and Character Education subjects for class VIII at SMP Negeri 1 Balige, Toba Regency, in the 2024/2025 Academic Year.

Acute Coronary Syndrome (ACS) is an emergency condition in which a group of symptoms of acute ischemic chest pain are part of coronary heart disease (CHD) and require immediate treatment. The prevalence of CHD in Aceh is higher than the national average of 1.6% or around 20,244 people. This study is expected to describe the prevalence, number of deaths (mortality) and average length of stay (LOS) of STEMI patients during hospitalization so that this data can significantly enhance knowledge for health practitioners and be used as a warning to be more aware of STEMI incidents in Aceh. This study uses a retrospective descriptive research design with a research sample of all patients diagnosed with ACS with ST-Elevation who were hospitalized at Dr. Fauziah Hospital in June 2022-June 2023. The data collection technique is total sampling obtained from medical record data. It was concluded that the majority of patients were male, namely 80.7% (71 patients), the highest age was 45-60 years with 45 cases (51.1%). History of CHD was the dominant risk factor (62% of cases). The most dominant type of ACS with ST-Elevation was Anterior STEMI as many as 32 cases (52.3%) with onset <12 hours (51% of cases) and predominantly came with KILLIP I (62.5% of cases). The most dominant management was with conservative therapy 56 cases (61.4%). The average length of patient care was 5 days (45.1%) and the most outcomes with outpatients as many as 72 cases (81.8%).

This study aims to describe the level of consumer liking or acceptance of a product, it absolutely requires a test called the organoleptic test and hedonic test This research was conducted in quantitative analysis In the implementation of this study, the experiment conducted was an experiment consisting of 4 treatments, Each treatment was carried out as many as 3 replicates so that 12 experimental units were obtained The treatments used were po (control) = regular sauce 100% Traditional chilli sauce packaging, p1 = 50% papaya sauce and 50% carrot sauce 500 grams of papaya + 500 grams of carrots, p2 papaya sauce (pure) 100% 1 kg papaya, p3 = carrot sauce (pure) 100% 1 kg organoleptic research results The highest colour was p1 4.3, aroma p3 3.9, taste p1 3.95, and texture p14. 25. As for hedonics, the highest was for colour p1 4.75, aroma p3 4.55, taste p1 4.25 and texture p3 4.5. Organoleptic tests involving colour, aroma, taste and texture showed values for colour in sample 1 with an average value of 4.3, aroma in sample 3 with an average value of 3.9, taste in sample 1 with an average value of 3.95 while texture in sample 1 with an average value of 4.25. The results of the hedonic test assessed consumer preference for sauces in samples 1 and 3 for sample I with an average value of 4.75 and a taste of 4.25 in the like category. While in sample 3 consumer assessment of aroma average value 4.55 and texture 4.5 category.

Noodles are commonly made from wheat flour, which is high in carbohydrates but low in fiber, vitamins, and minerals. To enhance their nutritional value, this study used broccoli leaf flour, a vegetable source rich in nutrients and antioxidants. The aim was to evaluate the organoleptic and chemical qualities of dried noodles with added broccoli leaf flour. The study used a completely randomized design with three treatments and two replications. Organoleptic tests (color, aroma, texture, and taste) were conducted by 60 panelists. Chemical analysis measured carbohydrate, protein, fat, calcium, fiber, and moisture content. The results showed that noodles with 10 grams of broccoli leaf flour (treatment B) were most preferred by panelists. This treatment also had improved nutritional content, especially in fiber and calcium, while maintaining acceptable product quality. In conclusion, broccoli leaf flour is a promising ingredient to improve the nutritional value of dried noodles and develop functional food that is well-accepted by consumers.

An experiment was conducted to study the effect of adding different levels of urea fertilizer (ppm Urea-N0,75,150,225,300) on the effectiveness of bio-nitrification in the studied soil. The study treatments for this experiment were (4 soils of different textures and locations × 5 urea levels × 3 replicates) in an experiment in which a completely randomized design (CRD) was used. It was incubated at laboratory temperature (25°C) for 40 days, during which the amount of formed nitrates and remaining ammonium was measured every ten days, noting the replacement of lost water every two days. The highest percentage of formed nitrates (39.8%) was recorded from the ammonium added to Basrah soil after ten days of incubation, followed by Kut soil, which recorded 29.8%, and less than that in Shatra soils (24.2%) and Fajr soils (23.7%). After that, the efficiency of nitrification decreased in the subsequent incubation periods up to 40 days of incubation.The percentage of ammonium remaining from urea added to the soil was recorded after the four incubation periods at 20.0 ppm (when adding 225 ppm urea to the Qurna soil), which differed significantly from the rest of the studied soils.

Nausea and vomiting are common discomforts experienced by 50% of pregnant women in the first trimester. One of the implementations to reduce nausea and vomiting with non-pharmacological therapy is the provision of lavender aromatherapy. The purpose of this study was to determine whether there was an effect of giving Lavender aromatherapy on nausea and vomiting in pregnant women in the first trimester at PMB Ronni Siregar Deli Serdang. The research method used was Quasi-experimental using nonequivalent control group design. The sampling technique used in this study was Total sampling based on Inclusion and Exclusion criteria, the number of samples was 30 respondents (15 intervention groups and 15 control groups). The results showed that the average value of respondents in the intervention group in the nausea and vomiting value before giving lavender aromatherapy was Mean 13.5 standard deviation 3,521. in the intervention group after being given treatment, a mean value of 10.6 was obtained with a standard division of 4,459. Based on the t-test, a p-value of 0.000 was obtained, which means it is smaller than the significant value <0.05. The conclusion of this study is that there is an Effect of Lavender Aromatherapy on Nausea and Vomiting in Pregnant Women in the First Trimester at PMB Ronni Siregar Deli Serdang. This study expects Midwives to provide health promotion and education, namely by improving their midwifery care, especially for Pregnant Women with nausea and vomiting during pregnancy, in addition to explaining the non-pharmacological benefits in reducing nausea and vomiting during pregnancy. 

Abstrak. Osteoporosis is a degenerative bone disease characterized by a decrease in bone mass and strength, particularly in postmenopausal women. Traditional plant-based therapy presents an attractive alternative given the rich local bioactive potential and limited access to pharmacological treatments. One important biochemical indicator in bone regeneration is the level of alkaline phosphatase (ALP). The aim of this study is to evaluate the potential of various Indonesian traditional medicinal plants as bioactive agents in the prevention of osteoporosis, with an emphasis on increasing ALP levels. This method employed a literature search by collecting several scientific articles discussing the anti-osteoporosis activity of traditional medicinal plants through in vitro, in vivo, and clinical observation studies. The results obtained show that traditional medicinal plants such as Turmeric (Curcuma longa), Black pepper (Piper nigrum), Bromelain (Ananas comosus), Papaya (Carica papaya), Japanese knotweed (Reynoutria japonica Houtt.), Veratrum nigrum, Sickle senna (Cassia tora), Red ginger (Zingiber officinale var. rubrum), Clove (Syzygium aromaticum L.), White turmeric (Curcuma zeadoaria), and Celery (Apium graveolens) are capable of reducing the number of osteoclasts and promoting bone formation. These findings consistently demonstrate a positive role in bone health through increased ALP levels. Indonesian traditional medicinal plants hold great potential as evidence-based anti-osteoporosis agents, particularly through enhancing ALP levels and osteoblast activity. This literature review supports the development of local herbal therapy as a promotive and preventive alternative against osteoporosis.

This study aims to analyze the effect of different mordant types on the quality of ecoprinted scarves, particularly in terms of color sharpness and motif clarity. A controlled experimental method was conducted by testing three types of mordants—alum, sodium acetate, and iron sulfate—on cotton fabric using the pounding technique. Each treatment was evaluated by 30 respondents to ensure statistical validity.  The results revealed significant differences (p<0.05) among the three mordants, with alum demonstrating the best performance, achieving a color sharpness score of 3.8 and motif clarity of 3.7, followed by iron sulfate (3.2 for color and 3.1 for motif), while sodium acetate yielded the lowest scores (2.6 for color and 2.9 for motif). The superiority of alum is attributed to the optimal fixation capability of Al³⁺ ions and pH stability within the range of 5.2–5.8. The research instruments were validated (r=0.92) and reliable (α=0.89).  These findings provide significant contributions to the advancement of ecoprinting techniques, particularly in mordant selection for producing high-quality textile products. 

Nausea and vomiting are common discomforts experienced by 50% of pregnant women in the first trimester. One of the implementations to reduce nausea and vomiting with non-pharmacological therapy is the provision of lavender aromatherapy. The purpose of this study was to determine whether there was an effect of giving Lavender aromatherapy on nausea and vomiting in pregnant women in the first trimester at PMB Ronni Siregar Deli Serdang. The research method used was Quasi-experimental using nonequivalent control group design. The sampling technique used in this study was Total sampling based on Inclusion and Exclusion criteria, the number of samples was 30 respondents (15 intervention groups and 15 control groups). The results showed that the average value of respondents in the intervention group in the nausea and vomiting value before giving lavender aromatherapy was Mean 13.5 standard deviation 3.521. in the intervention group after being given treatment, a mean value of 10.6 was obtained with a standard division of 4.459. Based on the t-test, a p-value of 0.000 was obtained, which means it is smaller than the significant value <0.05. The conclusion of this study is that there is an Effect of Lavender Aromatherapy on Nausea and Vomiting in Pregnant Women in the First Trimester at PMB Ronni Siregar Deli Serdang. This study expects Midwives to provide health promotion and education, namely by improving their midwifery care, especially for Pregnant Women with nausea and vomiting during pregnancy, in addition to explaining the non-pharmacological benefits in reducing nausea and vomiting during pregnancy.

Employee work motivation stands as a pivotal aspect capable of significantly enhancing employee performance within any organizational setting. This qualitative study endeavors to comprehensively gather information regarding the multifaceted factors that influence employee work motivation, ultimately impacting their overall performance. Utilizing a qualitative research methodology with a robust literature review approach, this investigation systematically reviews and synthesizes findings from an array of prior studies. The synthesis of our findings reveals two primary categories of factors critically affecting employee work motivation: external and internal factors. External factors encompass crucial elements such as the work environment, salary structures, the quality of supervisor treatment, and prevailing company policies. Conversely, internal factors primarily involve an individual's personal desires and inherent needs that require fulfillment within the employee. In light of these findings, it is imperative for organizations to address and fulfill these identified factors, particularly external ones, as a strategic endeavor to elevate and sustain employee performance.

Physiological quality deterioration during storage is a major factor contributing to the reduced germination capacity of rice seeds. Revitalization treatments are therefore essential to restore seed viability and promote optimal seedling development. One promising approach involves the application of plant growth regulators (PGRs) from the polyamine group, such as putrescine. This study aimed to assess the effectiveness of varying concentrations and soaking durations of putrescine in improving the viability of deteriorated rice seeds. The experiment was conducted using a Randomized Block Design (RBD) with two factors: putrescine concentrations (0 ppm/ soaking in distilled water only, putrescine 15 ppm, putrescine 20 ppm, and putrescine 25 ppm) and soaking durations (3, 6, and 9 hours). The parameters evaluated included germination percentage and germination rate. Results indicated that treatment with 20 ppm putrescine combined with a 6-hour soaking period yielded the most significant improvement in seed viability. These findings suggest that putrescine treatment can effectively restore the physiological quality of rice seeds affected by storage-induced deterioration.

Dextromethorphan (DXM) is a commonly used nonprescription cough suppressant that has gained field of science attention with its growing complex pharmacological effects and increased incidences of nonmedical use. This review is focused on pharmacokinetic, pharmacodynamics and CNS effects of DXM, especially on its action mechanism and the interaction with neural circuits and neurotransmitter systems. Although DXM has retained clinical utility as an antitussive, and has demonstrated potential as an off-label agent for neuropsychiatric disease, the recreational use of high doses can have harmful effects on the nervous system. At high doses DXM is capable of dissociation and hallucination similar to those induced by some opioids and NMDA antagonists, altering both mental status and cognition while being associated with neurotoxic effects. In this article, review and compare the similarities and differences between DXM and classic opioids in terms of their potential for abuse and their neurological effects. By case examples and existing epidemiological data, it also highlights the mounting abuse of DXM, most notably by children and young adults, posing a pressing public health challenge. Legislation on DXM is also described and differences in legislative response worldwide are highlighted. Finally, the article finishes by emphasizing the requirement for further studies involving other disciplines to detail the long-term neurological consequences of DXM abuse and to promote integrated public health interventions targeting education, prevention, and clinical treatment.

Salted eggs are one from of processed eggs that aims to extend shelf life and improve taste. Biology Education Studentsfrom the 2021 and 2022 classes are khown to only know straw and ash salting media, so this study aims to analyze the effect of four salting media: straw, brunt rice husk, burnt coconut fiber, and salt solution on the organoleptic quality of salted eggs. The research was conducted experimentally using a descriptive analysis approach using averages with 4 treatments and involving 20 panelists from two classes. The parameters tested included aroma, taste, color, and texture using a 5 level Likert scalee. The results of the organoleptic test showed that the burnt rice husk media produced the most preferred taste (score 3.4), the best color was produced by the straw media (score 4), and the highest texture was also found in the burnt rice husk media (score 3.6). The highest aroma was recorded in the straw media (score 3.35). The salt solution media had the lowest scores in almost all aspect. In conclusion, the burnt rice husk media is the most superior media overall in producing preferred salted eggs based on the organoleptic test.

Abstract. Background: Slimming drugs, such as phentermine, are widely used for weight reduction but are known to induce oxidative stress, particularly affecting hepatic and renal tissues. Selenium nanoparticles (SeNPs), especially those biosynthesized using natural sources like spirulina platensis, have demonstrated promising antioxidant and protective activities in biological systems. Objective: This study aimed to assess the protective effects of selenium nanoparticles synthesized from spirulina platensis extract on renal and hepatic functions in male rats exposed to phentermine induced oxidative stress. Methods: Twenty-six adult male wistar rats were divided into five experimental groups: control group (dosed with water n=5), SeNPs group (dosed with SeNPs n=5), phentermine group (dosed with phentermine n=5), SeNPs then phentermine group (dosed with SeNPs then phentermine n=5), phentermine then SeNPs group (dosed with phentermine then SeNPs n=5). The experiment lasted for 45 days, the measurement of cytokines IL-6, IL-12, TOS and TO-AC. Results: Phentermine administration significantly increased cytokines IL-6, IL-12 indicating marked oxidative stress and immune activation. Treatment with SeNPs alone or in combination with phentermine notably improved these parameters. The group dosed with SeNPs prior to phentermine (SeNPs then phentermine) showed the most prominent protective effects with values approaching those of the control. Conclusions: Selenium nanoparticles from spirulina platensis demonstrated significant protective, antioxidant, and immunomodulatory effects against phentermine induced immune disturbances. These findings support their potential

Burn injuries are complex tissue damage often accompanied by serious complications such as infection, systemic inflammation, and organ dysfunction. Effective burn management requires a comprehensive multidisciplinary approach, including infection control, local wound care, nutritional support, and regenerative therapy. Along with advances in science and technology, various novel treatment modalities have been developed to accelerate healing, reduce scarring, and improve patients’ quality of life. This study aims to evaluate the effectiveness and clinical prospects of the latest burn treatment modalities through a review of relevant literature from 2021 to 2025. This research employed a descriptive qualitative literature review method, analyzing 10 relevant scientific articles obtained from academic databases such as PubMed, ScienceDirect, and Google Scholar. The reviewed modalities include stem cell therapy, Platelet Rich Plasma (PRP), silver nanoparticles, nanofiber and hydrogel-based dressings, natural extracts such as aloe vera and binahong, as well as advanced technologies like smart dressings and low-level laser therapy. The results indicate that regenerative and smart technology-based approaches significantly enhance epithelialization, reduce infection, and improve tissue repair. Natural therapies also show promising potential as safe, affordable, and effective treatment alternatives. In conclusion, the integration of biological therapy, phytotherapy, and modern technology represents a promising direction in contemporary burn care. Further large-scale clinical research is needed to confirm the long-term safety and effectiveness of each modality.

Type 2 diabetes mellitus (T2DM), hypertension, anemia, nephrotic syndrome, and urinary tract infection (UTI) are interrelated clinical conditions frequently encountered in patients with chronic kidney disease (CKD). This case report presents a 33-year-old woman who was admitted with complaints of generalized weakness, accompanied by headache, generalized edema, and pruritus. Laboratory findings revealed hyperglycemia (>300 mg/dL), elevated blood pressure (210/120 mmHg), increased urea and creatinine levels, 2+ proteinuria, and microcytic hypochromic anemia (hemoglobin ranging from 7.9 to 9.9 g/dL). Urinalysis showed leukocyturia, hyaline casts, and bacteriuria. The patient was diagnosed with uncontrolled T2DM, hypertensive urgency, microcytic hypochromic anemia, nephrotic syndrome, and UTI. Management included basal-bolus insulin regimen, combined antihypertensive therapy, packed red cell transfusions, and supportive treatments. Throughout the hospitalization, improvements were observed in hemoglobin levels and blood pressure, although subjective symptoms such as fatigue and headache remained fluctuating. This case highlights the importance of comprehensive and multidisciplinary management in patients with complex multisystem chronic conditions to prevent complications and improve clinical outcomes.

Probiotics from West Sumatra curd have the potential to improve the production performance of local West Sumatra ducks, where Probiotics are live bacteria given as food sulpementation. Giving probiotics can have a beneficial effect on health where probiotics produce inhibitor compounds so that they can maximize the absorption of food in the intestines of livestock. The purpose of this study was to observe the production performance of ducks given probiotics. The design used was a randomized complete factorial method. The first factor (A) Dosage of probiotics (LAB) is with treatment A1: 1 ml (12.7 x 108 CFU/g); A2: 2 ml (25.4 x 108 CFU/g); A3: 3 ml (38.1 x 108 CFU/g). The second factor (B) is the frequency of probiotic administration, namely B1: 0 times; B2: 1 time; B3: 2 times; B4: 3 times; B5: 4 times; B6: 5 times; B7: 6 times, consisting of 4 replicates with a total of 346 ducks. The observed variables were food consumption, body weight gain, ration conversion, carcass percentage. The results of this study were the average food consumption at a dose of 3 ml with 5 times administration (995.79g). The highest average body weight gain (369.74 grams) dose of 1 ml and 5 times administration. The highest carcass percentage with a dose of 3 ml and a frequency of 5 times (72.63%).

Breast cancer is the second leading cause of cancer-related deaths in women, after cervical cancer. To date, breast cancer treatment still faces various challenges, particularly in terms of effectiveness and therapy-related side effects. Therefore, alternative treatments that are safer and more effective are needed, one of which is through the use of natural ingredients such as soursop leaves (Annona muricata). This review article aims to examine the potential of soursop leaf extract in slowing the growth of breast cancer cells. Several studies have shown that soursop leaf extract contains active compounds such as acetogenin, which are known to inhibit cancer cell proliferation, induce apoptosis, and block the formation of new blood vessels (anti-angiogenesis) in cancer tissues. These bioactive compounds make soursop leaves a promising candidate for natural anticancer agents. Thus, soursop leaf extract may be considered as a complementary therapy in the management of breast cancer.

This study aimed to measure the effectiveness of using AI Gemini in improving the writing ability of chronological essays among second-semester students of the English Education Department at Universitas Bhinneka PGRI. A quantitative approach with a pre-experimental one-group pretest-posttest design was applied. The instruments used were writing tests administered before and after the treatment. Data were analyzed using SPSS version 26 through descriptive statistics, normality testing, and hypothesis testing. The results indicated a significant improvement in the post-test scores, with a significance value (2-tailed) of 0.000 (<0.05). The mean pre-test score of 66.50 increased to 85.00 in the post-test. These findings demonstrate that the use of AI Gemini is effective in supporting students to improve their writing skills, particularly in grammar accuracy, sentence structure, vocabulary, and text coherence. This study also emphasizes the importance of applying AI tools in a balanced way to foster critical thinking and independent writing skills.

Varicella is a contagious skin infection caused by the varicella zoster virus (VZV). Varicella, scabies, and pityriasis versicolor are diseases with the same risk factors, namely in adolescents with high physical activity and living in crowded places such as dormitories. Case: A 13-year-old male adolescent complained of fluid-filled bumps on the body and face accompanied by itching that had been felt since yesterday. Low fever that fluctuates accompanied by dizziness, nausea since 2 days ago. Due to the itching, the patient scratched the area of ​​the bumps so that the bumps burst. The patient is currently undergoing scabies treatment. The patient also complained of white spots all over the body that had appeared since 2 months ago and worsened when the patient sweated. The patient is a student living in an Islamic boarding school. The patient said he often changed clothes, sarongs, and caps with his dorm mates. The patient also has high physical activity such as playing ball and does not immediately change clothes if he sweats. The diagnosis of varicella, scabies, and pityriasis versicolor is based on anamnesis and physical examination. Treatment options in this case are administration of drugs in the form of Acyclovir 400mg 4 x 2, Paracetamol 500mg 3 x 1, Permethrin 5% applied to the entire body 1x for 8 hours, Fucilex cream 2 dd ue, and Ketoconazole 2% shampoo. Conclusion: in this case, a 13-year-old patient with varicella, scabies, and pityriasis versicolor with risk factors of adolescence with high physical activity and living in crowded places such as dormitories was found.