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Durian leaves have secondary metabolites, namely flavonoids. Flavonoids have shown a wide range of bioactivity, one of which is an antipyretic effect which can be used as a febrifuge. This study aims to examine the antipyretic activity of the ethanol extract of durian leaves (Durio zibethinus L.) against male white rats (Rattus norvegicus) induced by DPT-HB-Hib vaccine. This study uses an experimental method. In this study, durian leaf extract was processed by maceration using 96% ethanol, then treated with secondary metabolites of simplicia and its ethanol extract. To pay for the antipyretic activity of durian leaves (Durio zibethinus L.) the test animals used were 25 and divided into 5 groups, namely negative control (CMC 0.5%), positive control (Paracetamol 1%) and the test dose group, namely the administration of leaf extract durian 200 mg/kg, 300 mg/kg and 400 mg/kg. Each rat was induced intramuscularly with the DPT-HB-Hib vaccine. Temperature measurements were carried out rectally with initial temperature measurements at 5 minute intervals 3 times, 1 hour after induction and 30 minutes for 3 hours. The data obtained were analyzed using the One-way ANOVA (Analysis of Variance) test and the Tukey HSD test. Based on the results of the study, it was shown that the results of the phytochemical screening of durian leaves contained flavonoids, saponins, tannins, alkaloids, steroids/triterpenoids. Of the three doses that experienced a decrease in temperature that was not significantly different from paracetamol, namely at a control dose of 300 mg/kg, because this decrease in temperature was almost close to paracetamol which was positive.

The purpose of this writing is to find out the procedure for cultivating Black Soldier Flies (BSF) maggot eggs on a household scale as fish feed. The stages of activities carried out are: 1) Consultation to mentors, 2) In-depth research, 3) Collection of materials. Maggot is a kind of natural food rich in protein. Maggot contains 41-42% crude protein, 31-35% ether extract, 14-15% ash, 4.8-5.1% calcium, and 0.6-0.63% phosphorus in dry form. To maintain BSF larvae, a suitable and quality substrate is needed. Optimal temperature and humidity affect the productivity of females in producing quality eggs. The mating process of BSF flies is strongly influenced by environmental factors and the behavior of adult insects

Sumbawa Besar Regency is one of the regencies in the West Nusa Tenggara region which has very abundant forestry resources. The forest is used as a business engaged in the extraction of forest products which is processed into various kinds such as Sumbawa oil which is produced in Kelungkung Village, Batulanteh District. The raw materials for making Sumbawa oil are obtained directly from the mountains and forests in the region which are efficacious as traditional medicines. The purpose of this study was to obtain a strategy and determine strategic priorities in the development of the Sumbawa oil agro-industry in Kelungkung Village, Batulanteh District. The stages of this research started with a field study by interviewing Sumbawa oil agro-industry players in Kelungkung Village, Batulanteh District. The analytical method used is SWOT analysis (Strengths, Weaknesses, Opportunities, Threats) and the QSPM matrix to obtain strategic priorities. Based on the results of the study, it was found that the position of the Sumbawa oil agro-industry was in quadrant I, namely supporting an aggressive strategy. Furthermore, based on the research results obtained by the QSPM matrix, 9 alternative strategies were obtained, and the prioritized strategy was to maintain and improve product quality according to tradition as a natural medicine that was of interest to consumers.

 Purslane plant is an herbal plant that is used as a medicine for skin infections. The author is interested in using the purslane plant as a peel-off mask to relieve acne nodules. The aim is to find out how to manufacture, sensory test results, public test results, and determine the effect of the purslane peel-off mask. This research was conducted with the methods of observation, experimentation, documentation, interviews, questionnaires, literature. The analysis used is descriptive qualitative analysis. The manufacture of purslane powder starts from the preparation of tools, materials, cleaning, drying, and refining. The manufacture of peel-off masks begins with the preparation of tools, materials, weighing, mixing, heating, and packaging. The feasibility of the product is tested based on color, aroma, texture, adhesion, product appearance. Product improvement is the addition of essence to the peel-off mask. In conclusion, according to the validator, the purslane plant powder is suitable for use in making peel-off masks and the results of the purslane peel-off mask facial treatment can relieve acne nodules. Suggestions for further researchers to change purslane plant powder into oil extract to maintain its content, BPOM test, and laboratory tests.

Puskesmas as one of the most important health services infrastructure has a task for give health services to the whole of society. Puskesmas is accused to always keep patient’s trust and satisfaction by give quality services. Quality services in the context of the services at Puskesmas mean give services to the patient based on standard quality for fill up necessary and anxiety of the society, so that they can get satisfaction which finally can increase patient’s trust to Puskesmas. This study aims to determine the quality of health services, the causal factors, and the demands and needs of the community. Measurements from service quality using the SERQUAL method and data extraction is done either quantitatively or qualitatively.

Nephrotic syndrome is a collection of symptoms characterized by massive proteinuria, hypoalbuminemia, edema and hypercholesterolemia. Snakehead fish contains important nutrients such as protein, omega-3 fatty acids, vitamins and minerals. Protein is the main building material in the body and is needed for albumin synthesis. Adequate protein consumption can provide the essential amino acids needed for albumin production in the body, thereby increasing albumin levels in the blood. The purpose of this study was to explain that snakehead fish extract has an effect on increasing albumin levels in patients with nephrotic syndrome based on a literature review. The research method uses a literature review study. The results of the study based on some of the literature that has been reviewed found that snakehead fish extract has an effect on increasing albumin levels in patients with nephrotic syndrome.

Betel leaves contain phenols that function as powerful antiseptics. Hand sanitizer (HS) is a product that can kill parasites on the hands and is easy to use. Therefore, in this event, education will be provided to the students of SMK Farmasi Surabaya regarding the benefits of betel leaves, followed by a training session on making hand sanitizers containing extract. The participant's level of understanding is evaluated by comparing the scores obtained before and after receiving information from the speaker. A questionnaire is given to allow participants to evaluate the overall conduct of the event, and they are invited to try the hand sanitizers prepared by the team. The results show that 76% of the participants achieved higher scores, 24% maintained the same scores, and none of the participants received lower scores compared to the pre-test. Overall, the participants expressed that the event was very beneficial.

In a steam power plant, of course, it has a very important prime mover, namely an electric motor, but electric motors are used in a variety of functions, one of the main roles in this electric motor is as a condensate extraction pump in a steam power plant which functions to push materials for power plant production. Steam power, namely sea water, goes to the generator to become a power plant. The method used is qualitative by using observation techniques, interviews and literature studies. This condensate extraction pump (CEP) electric motor can be operated automatically and manually for routine maintenance and good inspection results.    

Transparent solid soap, namely soap in the form of a bar with a transparent appearance, the resulting foam on the skin is softer. Saffron has been used as a food ingredient, treatment, and traditional medicine since ancient times. The content of saffron is like saponins which can be used in making transparent soap. This study aims to formulate a transparent soap from saffron essence as a skin protecting property. This research includes the manufacture of saffron extract, manufacture of transparent soap and transparent soap test parameters including organoleptic test, pH test, foam stability test, water content test and preference test by respondents. Based on research results, saffron extract can be formulated into transparent solid soap preparations that meet the requirements for water content in accordance with SNI, namely for F0 9.12 ± 0.56, FI 8.6 ± 0.42, F2 8.6 ± 0.43, F3 8.6±0.93. For the results of the foam height test, it was found that the foam results were quite stable. For the results of the irritation test, it can be concluded that soap preparations containing saffron essence are safe to use because they do not show any side effects after use.

Phenolic compounds are the largest group of compounds that act as natural antioxidants in plants. One of the plants that has the potential as a natural antioxidant is Jotang (Sphagneticola trilobata). This study aims to determine whether jotang leaf extract (Sphagneticola trilobata) has phenolic content and to determine the total phenolic content in jotang leaf extract (Sphagneticola trilobata). Jotang leaves were extracted by maceration method using methanol solvent. The method of determining total phenolic content was carried out using Folin-ciocaltaeu reagent because phenolic compounds can react with Folin-Ciocalteu to form a solution that can be measured absorbance. As a standard solution, gallic acid is used which is reacted with Folin-Ciocalteau reagent to produce a yellow color indicating that it contains phenolics, after which it is added with Na₂CO₃ solution as a base atmosphere giver. The phytochemical screening of jotang leaf extract showed positive results containing flavonoids, alkaloids, saponins, phenolic compounds, and triterpenoids. Determination of the wavelength of gallic acid obtained maximum 653 nm. The results showed that jotang leaf extract (Sphagneticola trilobata) has phenolic content and obtained total phenolic content of jotang leaf extract of 0.909 mg /g.

Background: Diabetes mellitus is a degenerative disease caused by the pancreas being damaged in production or insulin cannot work effectively. Portulaca Oleracea Leaf Extract can help reduce levels of Malondialdehyde. The purpose of this study was to analyze the effect of Portulaca Oleracea leaf extract on malondialdehyde levels in alloxan-induced rats as a diabetes model.Methods: There were 30 rats in this study divided into 5 groups, each group consisting of 6 rats. The negative control group was only given aquadest and standard rat feed, the positive group was induced with alloxan, the treatment group 1 was induced with alloxan and Portulaca Oleracea leaf extract at a dose 60 mg/200grBW, treatment group 2 was induced with alloxan and Portulaca Oleracea leaf extract at a dose 90 mg/200grBW and treatment group 3 was induced by alloxan and Portulaca Oleracea leaf extract at a dose 110 mg/200grBW rats. Analysis of the results used the One Way Anova test followed by Post Hoc LSD analysis to see differences between groups.Results: The results of One Way Anova test on Malondialdehyde levels showed that there was an effect after intervention of Portulaca Oleracea leaf extract among the five treatment groups p = 0.000. The results of Post Hoc LSD test showed that Portulaca Oleracea leaf extract had effective inhibits the formation of malondialdehyde activity at a dose of 90 mg/200grBB p = 0.145.Conclusion: It can be concluded that Portulaca Oleracea leaf extract can reduce Malondialdehyde levels.    

Acne is a skin disease due to chronic inflammation with complex pathogenesis. The public has empirically used the white plant to treat wounds on the skin, it contains flavonoids, saponins, and tannins which can protect the skin from bacteria and can inhibit bacterial growth. This study aims to test the antibacterial activity against Propionibacterium acnes. The ethanol extract of Putihan leaves was obtained by maceration using 96% ethanol solvent, formulated and evaluated for facial soap gel preparations of ethanol extract of Putihan leaves with various extract concentrations of 0% (F0), 10% (F1), 13% (F2), and 15% (F3) which testing antibacterial activity against Propionibacterium acnes. The results showed that the antibacterial activity of the facial soap gel preparation of ethanol extract of Putihan leaves with a concentration of 10% had an inhibition of 8.4 ± 0.20 mm, 13% had an inhibition of 9.5 ± 0.23 mm and 15% had an inhibition of 10.6 ± 0.64mm. Based on this description, the resulting gel preparation has antibacterial activity against Propionibacterium acne. The three formulas are included in the medium inhibition zone category, but the one with the broadest inhibition zone is at a concentration of 15%.  

Secang wood is one of the plants that contains many antioxidants, secondary metabolites and antibacterial compounds. This study aims to determine characterization of simplicia and chemical substances of Secang wood extract. Secang wood which was already in the form of simplicia was extracted by maceration using 96% ethanol solvent and the extract was concentrated with a rotary evaporator at a temperature of 40°C, then screening and characterization tests were carried out. The results of this study showed that phytochemical screening of the ethanol extract of sappan wood (Caesaloinia sappan L) showed the presence of flavonoid, tannin, saponin, alkaloid, steroid, and phenolic compounds. Characterization of simplicia obtained results at water content (3.95%) water soluble extract (11.01%), ethanol soluble extract (17.22%), total ash content (1.81%) and non-soluble ash content. acid soluble (0.28%).

Secang wood from the Caesalpiniacea tribe which was commonly found in Indonesia had secondary metabolites as antibacterial. This study aims to formulate secang wood ethanol extract into a transparent solid soap that is able to meet quality requirements. This research method was begin with formulating the extract into a transparent solid soap preparation with 3 concentrations, namely 5g (F1), 10g (F2), and 15g (F3). Furthermore, appearance tests, foaming ability, free alkali, free fatty acids, irritation, hedonic, and pH were carried out. The results of the research on transparent solid soap gave different colors for each concentration, namely transparent bright red (F1) and transparent dark red (F2 and F3) which were stable for 4 weeks; the foam power test shows a height of 4.5-6.5 cm after 10 minutes; free alkaline test shows a value of 0.07-0.08%; free fatty acid test 0.16%, and pH test 8.96-9.66 at week 4; and transparent solid soap does not cause irritation, attractive and liked by volunteers

Dengue Hemorrhagic fever (DHF) is caused by a dengue virus that spreads through the bite of the Aedes aegypti mosquito, which breeds a lot in densely populated areas with humid and warm climates. Anti-mosquito drugs in the form of burns, sprays, lotions, or other types are already widely used, but these anti-mosquito drugs are not entirely beneficial. This research is purely experimental research with Post-test Only Control Group Design by making air spray solution products from noni leaf infusion and cananga flower, which are analyzed descriptively and analytically. Experiments carried out with Randomized Complete Design 1 time repetition to analyze effectiveness. The study used two factors: treatment (P) using infusion products while the control (K) using distilled water. From the results of mixing, it was obtained as much as 400 ml of infusion solution. Obtained in each measurement, there was a reduction in live larvae until the last measurement. Noni leaf contains five flavonol glycosides (flavonoid compounds) as respiratory poisons and a combination of saponins and tannins as stomach poisons that have the killing power against the death of Aedes aegypti larvae. Cananga flower extract itself can resist mosquitoes because of the content of linalool, geraniol and eugenol. This makes a change in the larvae's behavior, where the previously active movement will be slow and eventually will die.

students need higher nutrition, increased growth and physical development, affecting intake and nutritional needs. Can be overcome with drinks made from natural ingredients. To determine the fiber content, nutrition and acceptability of grass jelly drinks with the addition of beets and soursop. With the addition of natural grass jelly extract, namely beetroot, soursop, the nutritional value of the formulation was tested for fiber content and its proximate value. Chopped beet products produce a fiber content of 1.48% and this product can be said to be a source of fiber if consumed per 250 ml or around 3.7 g of fiber. This is in accordance with BPOM.

Background : Constipation is a problem that is always disturbing in pregnant women, in general trimester pregnant women 3. Constipation is a difficult condition or unable to defecate, hard stool, a sense of defecation is not complete (there is a sense of wanting to defecate but unable to remove it) accompanied by complaints of the stomach feeling full and bloating. If this problem is left alone it will have an impact on the process of childbirth and childbirth. Objectives : The purpose of this study can be seen the effect of giving genjer extract as an alternative to prevent constipation during pregnancy at PMB Rusmiati Karang Tengah Tarumajaya Research Methods : This research design uses the quasi-experimental study method with pretest-posttest with control group design with a total of 32 respondents. The technique used in this study is a saturated sample. Results : The results of the study were found that after consuming the genjer extract of pregnant women who experience constipation into non-constipation it is shown in the occurrence of chapters for 2 weeks in pregnant women to normal. Conclusion : There is an effectiveness of the effect of providing genjer extract consumption as an alternative to prevent constipation during pregnancy.

Background : The period of breastfeeding in children aged 0-6 months is one part of the first 1,000 days of life (golden period). Exclusive breastfeeding aims to guarantee the right to exclusive breastfeeding up to the age of 6 months by taking into account the growth and development of the baby. Some mothers find it difficult to express breast milk because more and more mothers are influenced by myths. When a mother is concerned about her baby's ability to breastfeed, the hormone oxytocin decreases, causing her to stop producing and eventually breastfeed soon after birth. One way to stimulate the mother's prolactin and oxytocin hormones after giving birth is breastfeeding massage. Writing purpose : To determine the effectiveness of the combination of consumption of smoothy spinach and oketani massage to increase the amount of milk production in postpartum mothers in the UPT area dcomparison of giving snakehead fish extract and smoothy spinach to increasing hemoglobin levels in pregnant women in the UPT Puskesmas Kalri Karawang area in 2023. Research methods : This type of research used is quantitative research. This research method is experimental with the type of Quasy Experimental (pseudo-experimental) with a post test only design approach.This research was conducted in the UPT Kalri Health Center, Karawarang December 2022 to January 2023. The population in this study were all postpartum mothers at the Mukoyurli Buol Hospital with a total of 63 people. Samples were taken using non-probability sampling method with purposive sampling technique. The number of samples in this study were 32 research samples. Research result : The results of the independent statistical test sample T test obtained a value of p = 0.000 (p <0.05), which means that the combination of smoothy spinach and massage oketani has a significant effect on milk production. Conclusion : There is a significant relationship between the combination of smoothy spinach and oketani massage on milk production.It is hoped that health workers (doctors, midwives, nurses) can assist postpartum mothers in communicating providing information and education about the benefits of a combination of smoothy spinach and oketani massage in helping patient families to provide oxytocin reflex massage to postpartum mothers.