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Burn injuries are complex tissue damage often accompanied by serious complications such as infection, systemic inflammation, and organ dysfunction. Effective burn management requires a comprehensive multidisciplinary approach, including infection control, local wound care, nutritional support, and regenerative therapy. Along with advances in science and technology, various novel treatment modalities have been developed to accelerate healing, reduce scarring, and improve patients’ quality of life. This study aims to evaluate the effectiveness and clinical prospects of the latest burn treatment modalities through a review of relevant literature from 2021 to 2025. This research employed a descriptive qualitative literature review method, analyzing 10 relevant scientific articles obtained from academic databases such as PubMed, ScienceDirect, and Google Scholar. The reviewed modalities include stem cell therapy, Platelet Rich Plasma (PRP), silver nanoparticles, nanofiber and hydrogel-based dressings, natural extracts such as aloe vera and binahong, as well as advanced technologies like smart dressings and low-level laser therapy. The results indicate that regenerative and smart technology-based approaches significantly enhance epithelialization, reduce infection, and improve tissue repair. Natural therapies also show promising potential as safe, affordable, and effective treatment alternatives. In conclusion, the integration of biological therapy, phytotherapy, and modern technology represents a promising direction in contemporary burn care. Further large-scale clinical research is needed to confirm the long-term safety and effectiveness of each modality.

Pulmonary tuberculosis (TB) remains a major public health concern in Indonesia. Active family involvement in both prevention and treatment is crucial; however, many families have yet to fulfill their health-related responsibilities effectively. This study aimed to evaluate the effect of health education through the IKAT TB (Tuberculosis Health Information) application on family health responsibilities in the prevention and treatment of pulmonary TB. A pre-experimental design with a one-group pretest-posttest approach was used. The sample consisted of 46 respondents selected through total sampling. The intervention involved providing education via the IKAT TB application, and data were collected using a family health responsibility questionnaire. Data were analyzed using the Wilcoxon Signed Rank Test. The results showed an increase in family health responsibility scores following the educational intervention. The Wilcoxon test produced a p-value of 0.000 (p < 0.05), indicating a significant difference between pre- and post-intervention scores. The findings suggest that health education delivered through the IKAT TB application is effective in enhancing family engagement in TB prevention and treatment. Digital media platforms such as mobile applications offer accessible information and can strengthen family involvement in TB care.

Indonesia is known as a megabiodiversity country with high biological wealth, including a variety of medicinal plants that are traditionally used by various ethnic groups. One of them is the Tengger Tribe in Lumajang Regency, East Java, which until now still maintains traditional medicinal practices based on medicinal plants. This study aims to explore and document the types of medicinal plants used by the Tengger people, the parts of the plants used, the content of active compounds, efficacy, and pharmacological mechanisms of action based on scientific data. The method used is a literature study by searching for scientific articles through Google Scholar and PubMed in the period 2010–2024. The results of the exploration found at least 15 types of medicinal plants that are often used by the Tengger people, including Eucalyptus globulus, Curcuma longa, Zingiber officinale, and Psidium guajava. These plants have active compounds such as eucalyptol, curcumin, gingerol, and quercetin which work through anti-inflammatory, antibacterial, immunomodulatory, and antioxidant mechanisms. Some of them have been tested preclinically and clinically to support their traditional efficacy. This study emphasizes the importance of scientific documentation and validation of local ethnobotanical knowledge as a basis for the development of phytopharmaceuticals and the preservation of traditional Indonesian health culture.

Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis. Indonesia is one of the countries with the highest number of TB cases in the world. The key to successful TB treatment is treatment adherence. One factor that influences treatment adherence is stigma, which can result in incomplete treatment. This study aimed to determine the relationship between stigma and adherence to pulmonary TB treatment in the city of Lhokseumawe. The research method used was descriptive correlational with a cross-sectional approach. The sampling method was quota sampling with a sample size of 83 pulmonary TB patients. Data were filled in by filling out the Internalized Stigma of Mental Illness (ISMI) scale and Morisky Medication Adherence Scale (MMAS-8) questionnaires, and the data were analyzed using the Spearman correlation test (p = 0.05). The results of the bivariate test of age, gender, last education, occupation, and PMO did not have a relationship with adherence to pulmonary TB treatment, with a p value> 0.05. However, the duration of treatment had a relationship with the level of adherence to pulmonary TB treatment, with a p-value = 0.008. The study's results also showed that stigma and treatment compliance did not have a significant relationship, with p-value = 0.197. It was concluded that there was no relationship between stigma and compliance with pulmonary TB treatment. Health services in Lhokseumawe City are expected to continue to provide education and motivation to pulmonary TB patients to comply with their treatment.

Tuberculosis is still a health problem in the community, regular treatment can minimize transmission, and the combination of herbal medicine with anti-tuberculosis drugs can reduce tuberculosis symptoms. Currently, the community does not understand herbal medicine for the treatment of tuberculosis symptoms. Health education is needed for information about the benefits and impacts of herbal medicine in the treatment of tuberculosis. The purpose of this community service is to provide information to families as a companion to the use of herbal medicine for the treatment of tuberculosis symptoms. This community service uses a participatory Action Research (PAR) approach. This approach allows for active interaction with the community. This community service uses lecture and discussion methods for families at risk of tuberculosis, education is given with a time of 1 (one) meeting with a duration of 60 minutes. The media used are leaflets and booklets to make it easier for families to understand herbal medicine. The results obtained after health education were carried out were an increase in family understanding of the benefits and side effects of using herbal medicine for the treatment of tuberculosis symptoms. It is hoped that health education can provide information about the use and side effects in the treatment of tuberculosis symptoms. Keywords: Health education, Herbal Medicine, Tuberculosis

Degenerative diseases such as cancer have a significant impact on overall health and are a leading cause of death worldwide. Identifying phytochemicals with potential preventive and therapeutic properties is crucial in combating these diseases. Apigenin, a flavonoid phytochemical, has garnered attention due to its potential role in cancer prevention and treatment. Therefore, the aim of this research is to prioritize an approach to cancer treatment based on more effective and fewer side effects. Apigenin, a plant-derived flavonoid, has received significant scientific consideration for its potential health-enhancing effects through modulation of inflammation, oxidative stress, and various other biological activities. This review utilizes online scientific articles from reputable platforms such as PubMed, Google Scholar, and Springer Link. The objective of this research is to explore the potential role of apigenin as a promising phytochemical in cancer prevention and treatment, elucidating its therapeutic mechanisms and future research directions.

Non-communicable diseases (NCDs) are the leading cause of death globally, with type 2 diabetes being one of the most prevalent conditions. Nutritional management for clients with type 2 diabetes requires strict adherence to the correct schedule, type, and quantity of food. To improve medication adherence, it is essential to implement preventive strategies that promote patient engagement and self-management. One such strategy is the Health Belief Model (HBM), which encourages patients to adopt healthy behaviors based on their perceptions of risk, severity, benefits, and barriers. This study aims to analyze the relationship between the Health Belief Model and medication adherence among type 2 diabetic patients in the Galala Community Health Center (Puskesmas) work area. A quantitative cross-sectional study design was used, with a sample size of 108 participants selected through simple random sampling. The independent variables in this study were perceived susceptibility, perceived severity, perceived benefits, perceived barriers, and cues to action, while the dependent variable was medication adherence. The results revealed significant relationships between all the HBM constructs and medication adherence. Specifically, perceived susceptibility (p=0.000), perceived severity (p=0.000), perceived benefits (p=0.000), perceived barriers (p=0.000), and cues to action (p=0.000) all had strong associations with adherence to medication. The findings suggest that the Health Belief Model is a valuable framework for improving medication adherence among type 2 diabetes patients. Additionally, the use of health information technology is an effective strategy to increase patient awareness of the risks of non-adherence and the importance of regular medication intake. A combination of education, social support, technology, and an individualized approach can create a supportive environment that encourages patients to manage their treatment effectively.

Tuberculosis (TB) is a global health problem, with Indonesia having the second highest number of cases in the world. Although morbidity and mortality rates from TB are still high, the disease is curable with proper treatment. The success of TB therapy can be influenced by various factors such as patient compliance, knowledge about TB, patient motivation, family support, education level, socioeconomic conditions, access to health facilities, the role of health workers, drug side effects, and comorbidities. This study aims to analyze the factors that influence the successful treatment of TB patients at Puskesmas Sentosa Baru. This study used a qualitative method with a cross-sectional descriptive approach, this study involved 15 TB patients who were interviewed in depth until the data reached the point of saturation, as well as observation and documentation. From the results of the research conducted, it was found that the factors that influence the success of patient treatment at Sentosa Baru Health Center are the level of patient compliance, level of knowledge, and patient motivation. Patients who have a better understanding of the disease tend to be more disciplined in undergoing therapy, while family support is a strong driver in improving patient adherence to treatment. Therefore, increased education, monitoring of adherence, and more intensive social support are needed so that patients can complete treatment optimally and break the chain of TB transmission.

Halitosis, or bad breath, is a multifactorial condition that is often caused by anaerobic bacterial activity in the oral cavity, especially on the dorsum surface of the tongue. The use of natural ingredients as an alternative halitosis treatment is a concern, one of which is the nutmeg plant (Myristica fragrans), which has various active compounds such as essential oils, saponins, flavonoids, and alkaloids. This study aims to assess the potential of nutmeg plants in inhibiting the growth of bacteria that cause halitosis through a literature review of 30 national and international journals within the last five years. The results showed that nutmeg extracts, both from seeds, pulp, and leaves, have antibacterial activity against various types of halitosis-causing bacteria such as Streptococcus mutans, Staphylococcus aureus, and Escherichia coli. This activity is obtained through the mechanism of cell membrane damage and inhibition of bacterial cell wall synthesis by bioactive compounds in nutmeg plants. Therefore, nutmeg has potential as a natural antibacterial agent in the management of halitosis.  

Tanpa hak menjadi perantara jual beli narkotika merupakan suatu perbuatan yang bertentangan dengan hukum dan masuk dalam rumusan deli sebagaimana dirumuskan dalam Pasal 8 Undang-Undang Nomor 35 Tahun 2009 tentang Nakotika. Dengan demikian tanpa hak menjadi perantara dalam jual beli Narkotika yang dimaksud dalam Putusan Putusan Negeri Jakarta Selatan Nomor 152/Pid.Sus/2024/PN Jkt.Sel., dan Putusan Nomor 207/Pid.Sus/2024/PN Jkt. Sel., yaitu seorang yang tidak berhak atas Narkotika Golongan I atau yang menggunakannya tidak untuk kepentingan pengobatan, tidak mendapatkan izin, dan melakukan perantara jual beli dengan melawan hukum. Penelitian ini akan menganalisis dasar pertimbangan hakim dalam memutuskan perkara dan tindak pidana tersebut menurut hukum pidana. Jenis Penelitian ini termasuk dalam penelitian pustaka (library research), sehingga mengambil dan mengolah data dari sumber-sumber kepustakaan seperti buku-buku dan jurnal yang terkait dengan penelitian ini. Pendekatan yang digunakan adalah penelitian hukum normatif (yuridis normatif) atau penelitian doktrinal. Metode pengumpulan data penelitian ini adalah metode dokumentasi yakni data-data yang dikumpulkan dari sumber dokumen yang ditulis atau dibuat langsung oleh subjek yang bersangkutan. Dan analisis yang digunakan adalah Teknik analisis isi (Content Analysis), yaitu suatu teknik dipergunakan dalam menganalisis terhadap isi suatu informasi secara tertulis yang bertujuan untuk menarik kesimpulan dari informasi yang dianalisis tersebut. Penelitian ini menunjukan bahwa pertimbangan hakim dalam memutuskan perkara didasarkan pada alat bukti dan fakta-fakta yang telah terungkap di persidangan, terdakwa melakukan tindak pidana tanpa hak menjadi perantara jual beli narkotika dengan dakwaan alternatif yaitu melanggar Pasal 114 ayat (2) Nomor 35 tahun 2009 tentang Narkotika dan didakwa dengan dakwaan kesatu. Jual beli narkotika memiliki arti perbuatan-perbuatan yang dilarang oleh undang-undang dan dari perbuatan tersebut pelaku kejahatan akan mendapatkan sanksi hukuman karena dalam perkara ini pelaku melakukan tindak pidana.

Masalah kesehatan internasional adalah hipertensi, penyebab utama gagal ginjal, stroke, dan penyakit jantung. Diperkirakan 34,1% orang di Indonesia menderita hipertensi, dan sebagian besar dari mereka tidak mendapatkan pengobatan. Meskipun Puskesmas Welahan 1 menangani hipertensi, pasien sering mengalami kesulitan mengontrol tekanan darah mereka karena berbagai macam obat yang tersedia. Tujuan dari penelitian ini adalah untuk mengetahui seberapa efektif terapi monoterapi dan kombinasi untuk mencapai target tekanan darah pasien hipertensi di Puskesmas Welahan 1 dan bagaimana berbagai obat mempengaruhi kontrol tekanan darah. Data dari 60 pasien hipertensi yang memenuhi kriteria inklusi dianalisis selama tiga bulan menggunakan pendekatan cross-sectional. Digunakan statistik inferensial dan deskriptif, seperti uji chi-square. Tidak ada korelasi signifikan antara kontrol tekanan darah sistolik dan diastolik dan jenis terapi obat (p > 0,05). Namun, pasien yang menerima amlodipine atau amlodipine + captopril lebih mampu mengontrol tekanan darah mereka, dengan rasio kemungkinan 0,857 untuk tekanan sistolik dan 6,429 untuk tekanan diastolik, masing-masing.  Hasilnya menunjukkan bahwa terapi kombinasi mungkin membantu mengontrol tekanan darah diastolik, meskipun jenis obat tidak mempengaruhi tekanan darah secara langsung

Alternative medicine using supernatural powers is a traditional practice widely found in Indonesia, but it is often conducted without scientific basis, causing negative impacts on society. These impacts include physical, financial, and psychological harm, such as delayed medical treatment leading to fatal outcomes, financial exploitation, and emotional manipulation. Article 252 of the 2023 Penal Code (KUHP) regulates this practice by imposing criminal sanctions on those who violate the law or harm the public. This regulation aims to protect the public, promote transparency, and integrate safe traditional elements into a modern, evidence-based medical system.

Acne is a skin disease caused by the bacteria Propionibacterium acnes, which infects the oil glands and pores of the skin. Hormonal changes that occur during puberty cause acne which is common in teenagers. With this problem, the community service team conducted education aimed at increasing the knowledge of teenagers to maintain their skin when acne occurs. The method of the activity was carried out with education with the material Introduction to Acne Infection Disease, Symptoms, Prevention and Treatment, the education participants were Elementary Madrasah and Junior High School students of the Ummul Quro Al-Hamidiyah Foundation totaling 50 students. The activity was carried out on Thursday, December 19, 2024. The results of the activity showed that the students were very enthusiastic about participating, and the students had understood what was explained by the speaker. The conclusion of the activity showed that there was an increase in student knowledge after being given education with the material on acne infection disease, symptoms, prevention and treatment in teenagers.

Bioprinting 3D merupakan suatu teknologi transformatif dalam konstruksi rekayasa jaringan dan prototipe organ untuk meniru karakteristik jaringan alami yang digunakan dalam pengobatan regeneratif. Secara bioetika, organ tiruan 3D melibatkan analisis dan evaluasi tentang implikasi moral, sosial, dan hukum dari penggunaan teknologi. Metode yang digunakan dalam penelitian ini adalah systematic literature review dengan menyajikan gambaran yang komprehensif tentang pengembangan dan pemanfaatan teknologi organ tiruan 3D (bioprinting) dalam perspektif bioetika dan hukum islam. Hasil menunjukkan bahwa bioprinting 3D memiliki pengaplikasian yang sangat beragam, diantaranya dalam bidang medis contohnya model untuk studi penyakit dan uji obat, pengobatan regeneratif, pembentukan organoid dan jaringan khusus, dan masih banyak lagi. Aspek bioetika mengenai bioprinting 3D masih menimbulkan tantangan yang perlu dipertimbangkan. Masalah bioetika seperti sumber atau asal bahan yang digunakan dalam bioprinting masih menjadi permasalahan. Penggunaan sel punca embrionik masih kontroversial, karena melibatkan penghancuran embrio manusia, sehingga menimbulkan pertanyaan moral dan etika mengenai nilai dan kesucian hidup manusia. Dalam perspektif Islam, berdasarkan analisis dari Al-Quran, hadits, dan beberapa fatwa, produksi organ tubuh melalui metode cetak 3D disarankan untuk dikategorikan sebagai perubahan ciptaan Tuhan yang dibolehkan karena tujuannya untuk mengobati dan menyelamatkan nyawa atau khusus untuk penggunaan proses transplantasi organ.

Moringa oleifera plants as traditional medicine used by the people of Cibeas Village, Cintaraja Village, Singaparna District, Tasikmalaya Regency. This study aims to determine the use of moringa plants as traditional medicine. The method used is descriptive qualitative and quantitative with data collection techniques through observation, semi-structured interviews, and snowball sampling. Data analysis was carried out by calculating the utility value (Use Value/UV), informant context factors (Informant Consensus Factor/ICF), and relative citation frequency (Relative Frequency of Citation/RFC). The results showed that moringa plants are used to treat 12 types of diseases, with the highest utilization for lowering hypertension (UV = 0.296). The leaves are the most frequently used part (ICF = 0.952).

Background: Pulmonary tuberculosis (TB) is an infectious disease that requires long-term treatment and patient compliance so that the healing process can be achieved properly. One of the factors that plays an important role in the success of pulmonary TB treatment is family support. Families who are directly involved in care and motivation can increase the patient's enthusiasm to complete treatment. Therefore, empowering families in supporting pulmonary TB treatment is very important to reduce the number of failed treatments and prevent drug resistance. This community service aims to empower families in providing effective support to pulmonary TB patients so that patients can complete their treatment completely. The empowerment program carried out through counseling on the importance of adherence to TB treatment, as well as training on how to care for patients and reduce social stigma against TB, is expected to increase the active role of families in supporting patient treatment. This community service activity involves families of pulmonary TB patients, medical personnel, and the surrounding community, with an educational and collaborative approach. The results of this community service show an increase in family understanding of TB disease, the importance of adherence to treatment, and a reduction in stigma against TB patients. In addition, families feel more prepared and motivated to support patients in undergoing treatment. Family empowerment has been proven effective in increasing the completion rate of pulmonary TB treatment, which in turn can reduce transmission rates and drug resistance.

Hypertension is the leading cause of premature death worldwide. To reduce the risk of hypertension, what needs to be done is hypertension treatment as an effort to control hypertension, one of which is non-pharmacological treatment, usually carried out by implementing the use of pandan wangi plants. Pandan wangi is a plant whose leaves are often used as a food additive. The purpose of implementing Community Service activities in Lorong Putri is to increase public awareness, especially the elderly, about Hypertension and the treatment of Hypertension with traditional medicine. Using the method of providing education and question and answer discussions related to dangerous conditions and efforts to prevent hypertension, participants in this activity were carried out on October 7, 2024 at Lorong Putri, Air Besar Health Center Work Area. totaling 20 people. During the Education Process, participants listened carefully and provided good feedback, in the form of benefits and how to consume boiled pandan leaf water, and whether it can be boiled together with drinking water at home, and all questions from participants can be answered well. With questions and answers from participants, participants can better understand hypertension and how to treat it with traditional medicine.

In Indonesia, traditional medicine has a legal position that is recognized and protected by state law in the provisions of article 50 paragraph (1) and paragraph (2) of Law Number 36 of 2009 concerning Health. It is also stated in the new Law Number 17 of 2023 concerning health article 192 paragraph (1). Although traditional medicine is recognized and regulated by national law, traditional medicine practitioners can also engage in malpractice acts. Currently, people have a lot of problems with traditional medicine, which is too prone to mishandling patients' diseases because of its methods that have not been clinically tested. The increasing number of cases of fracture infection caused by fracture shamans every year is one example of inappropriate handling that occurs in the Kemak Tribe in Kampung Sadi, Belu Regency. This research is a socio-legal research supported by an empirical approach that uses primary data and secondary data collected using interview and observation techniques and processed and dialysed using Editing, Coding, Verification, and Interpretation techniques. The results of this study show that (1) Negligence in traditional medicine is a serious problem that has a wide impact on individuals and society. (2) In traditional medicine, the prevention and control of negligence requires a comprehensive approach through education, regulation, and cooperation between the government, practitioners, and conventional health workers.

This study aims to describe the implementation of free acupuncture treatment as a form of community service carried out through collaboration between the Student Executive Board (DEMA) of the Islamic Economics College (STIES) and the Islamic Business Management Study Program in Trayeman Village. This free treatment is held to provide alternative health services to the underprivileged community, while introducing acupuncture as a non-medical treatment therapy that can help overcome various health complaints. The method used in this activity is direct treatment in the field by involving students and lecturers as medical personnel and companions. The results of the implementation of this treatment show an increase in public awareness of alternative medicine, as well as active community participation in the activity. The collaboration between DEMA STIES and the Islamic Business Management Study Program has also been proven to have a positive impact in terms of managing structured and well-coordinated community service activities. This activity is expected to be a model of community service that can be implemented more widely in various regions.

TB is an infectious disease caused by infection with the bacteria Mycobacterium Tuberculosis which can attack the lungs. However, it is not automatically transmitted because transmission depends on several factors such as: body resistance, air circulation conditions, ventilation and contact with people with TB. Based on hospital data in 2024 in the last 3 months, there were 317 cases of pulmonary TB, with 176 cases of patients diagnosed with TB. Treatment can be effective if patients comply with the rules for using drugs prescribed by doctors and from the results of the analysis there is a significant relationship between compliance with taking medication and the rate of recovery of tuberculosis patients. This figure is the third largest case of the disease after type 2 Diabetes Mellitus and Hypertension that occurred at Bhakti Asih Hospital. The purpose of the study was to determine the relationship between stigma and the level of patient compliance in TB treatment at Bhakti Asih Hospital, Ciledug. The research method used was Random Sampling with a sample size of 44 respondents and a measurement method using a questionnaire. The results of the analysis using the chi-square test showed that there was a significant relationship between stigma and compliance with taking pulmonary tuberculosis medication in lung patients at Bhakti Asih Hospital.