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Anemia is a problem of health in young women. Anemia is a condition in the concentration levels of hemoglobin in the blood is low, one of the efforts to improve the levels of Hemoglobin by non Pharmacology given soy edamame. Is a kind of soy beans which the iron content of substance more than other types. In addition to iron, also contained Vit C, B12, and folic acid, which is also a constituent of hemoglobin in the blood. The purpose of this research is to know the effect of granting soy edamame to increased levels of hemoglobin in on young women. The research design used was quasy eksperiment. Population of young women who are experiencing anemia in boarding schools of Tahfiz Hisbah Al Fatih as many as 20 people, with the total sampling techniques. Research instrument is the observation sheet and tool checks digitally Hemoglobin. Results of the study were analyzed using paired t-test Test and independent t Test. The results obtained from this research is the following value mean increased levels of Hb after given Soy edamame was 0.46 gdl and mean increased levels of Hb after administering a local soybean is 0.18 gdl. This indicates that after the granting of the soy edamame tablet better if compared to a local soybean delivery after this. Research analysis of Hb levels after administering a local soybean or edamame soybeans gained ρ-value 0.006 (α = 0 .05), then it can be inferred that H0 is rejected and there is meaning accepted H1 influence awarding of soy edamame to increased levels of Hb teen daughter in boarding schools of Tahfiz Hisbah Al Fatih. For young women in particular are expected to eat green vegetables and legumes, especially soy edamame to prevent as well as treat mild anemia.

Adolescents are a vulnerable age group to nutritional problems due to increased nutritional requirements during periods of rapid growth. Suboptimal nutritional status, including undernutrition and anaemia, can negatively affect health and academic performance. This study aimed to describe the nutritional status of adolescents at SMA Negeri 2 Kendari, Southeast Sulawesi Province. This study employed a descriptive observational design conducted from August to September 2025 with a total sample of 226 twelfth-grade students’ selected using proportionate stratified random sampling. Data were collected through measurements of body weight and height to determine nutritional status based on the BMI-for-Age indicator and haemoglobin levels were assessed using a digital haemometer. Data were analyzed using univariate analysis. The results showed that most respondents had normal nutritional status (52.2%), while a considerable proportion were undernutrition (47.8%). In addition, more than half of the respondents were anaemia (50.9%). These findings indicate that although anthropometric nutritional status was generally normal, anemia remains a health problem that requires attention among adolescents. Regular monitoring of nutritional status and hemoglobin levels accompanied by nutrition education is recommended. Further studies are recommended to use an analytical study design to identify factors associated with nutritional status and anaemia.

Anemia during pregnancy is a significant maternal health issue with serious impacts on maternal and perinatal outcomes, including complications such as severe preeclampsia, postpartum hemorrhage, and low birth weight (LBW), all of which contribute to increased morbidity and mortality rates. This literature review aims to analyze the clinical impacts of pregnancy anemia, related complications, and effective management strategies based on the latest scientific evidence (2020-2024). The study examines the relationship between anemia and preeclampsia, LBW, and postpartum hemorrhage, as well as the importance of nutritional fulfillment in prevention and management. Five research articles from indexed journals were collected from the Scopus database, with inclusion criteria of studies with clear designs, focusing on pregnancy anemia, and published in Indonesian or English. The analysis results show that pregnancy anemia is a predisposing factor for preeclampsia through mechanisms such as placental hypoxia and oxidative stress. Anemia is also closely related to an increased incidence of LBW and postpartum hemorrhage, particularly due to lower hemoglobin reserves and uterine contractility issues. Adequate nutritional fulfillment is influenced by socioeconomic barriers, supplementation side effects, and lack of family support. Anemia management requires a comprehensive approach, including routine screening, prophylactic supplementation, nutritional education, and effective referral systems for complex cases. Prevention through early detection and timely intervention is crucial in reducing maternal and perinatal morbidity.

Background: Anemia in pregnancy increases the risk of maternal and fetal morbidity and mortality, with a higher incidence in the third trimester. Although Fe tablets serve as the main therapy, non-pharmacological alternatives such as beetroot and lemon juice also have the potential to raise hemoglobin levels. Objective: To determine the effect of consuming beetroot-lemon juice combined with Fe tablets on hemoglobin levels in third-trimester pregnant women in Semarang. Method: This study applied a quasi-experimental design with a two-group pre-test post-test approach, allowing the measurement of hemoglobin level changes before and after the intervention. The study population consisted of all pregnant women in their third trimester, with gestational ages between 32 and 38 weeks, registered at two community health centers: PMB Puji Widiastuti, Amd.Keb, with 16 anemic respondents, and PMB Ika Febri Setyaning Astuti, Str.Keb, with 15 anemic respondents. A total of 31 respondents were obtained using total sampling. Data collection was conducted through observation sheets, and analysis was performed using the Mann Whitney statistical test. Results: The intervention group, which consumed beetroot and lemon juice along with Fe tablets, achieved a Mean Rank of 13.41, whereas the control group recorded a Mean Rank of 18.77, with an effectiveness difference of 5.36. Statistical analysis yielded a p-value of 0.048, indicating a significant difference between the groups. In conclusion, the combination of beetroot and lemon juice with Fe tablets effectively increased hemoglobin levels among third-trimester pregnant women with anemia. This finding suggests that such combination therapy can serve as a valuable alternative in the management of anemia during pregnancy.

Blood transfusion requires the availability of high-quality blood, which is determined, among others, by the donor's hemoglobin (Hb) level. One factor that may affect Hb is sleep quality. Objective: This study aims to determine the relationship between sleep quality and hemoglobin levels among prospective blood donors at UDD PMI South Sulawesi Province in 2025. Methods: An observational analytic study with a cross-sectional design was conducted involving 100 respondents selected using purposive sampling. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), while Hb levels were measured using a hemoglobinometer. Data analysis was performed using the Chi-Square test with a significance level of p ≤ 0.05. Results: The majority of respondents (75%) had good sleep quality, while 25% had poor sleep quality. Normal Hb levels (12.5–17 g/dL) were found in 96% of respondents, while 3% were low and 1% were high. The Chi-Square test showed a significant relationship between sleep quality and Hb levels (p = 0.050). Conclusion: Good sleep quality is significantly associated with normal hemoglobin levels in prospective donors. Educational programs about healthy sleep patterns before donation are necessary to improve donor eligibility and ensure a safe blood supply.

Cancer is a disease caused by the abnormal growth of body tissue cells. Breast cancer is one of the leading causes of death for women worldwide. The 5-year survival rate approaches 97% when tumor cells are confined to breast tissue and drops dramatically to 23% when tumor cells have metastasized to other organs at the time of diagnosis. Myelosuppression is a side effect of chemotherapy in cancer patients. Myelosuppression is a decrease in the number of hemoglobin, platelets, neutrophils, and leukocytes below normal, leading to anemia, thrombocytopenia, neutropenia, and leukocytopenia. This study aims to determine the effect of chemotherapy on leukocyte and platelet counts in breast cancer patients. This study is a qualitative descriptive study that describes the research topic data using a similar approach to the topic of the literature review. The results of this study indicate that most breast cancer patients undergoing chemotherapy experience a decrease in platelet and leukocyte counts

Globally, 33% of all productive women aged 15-49 have anemia problems. Anemia is a condition where there is a deficit of erythrocyte cells, which is often found in all age groups, including women of childbearing age (WUS) and young women, namely 29% of young women and non-pregnant women and 38% of pregnant women have problems with anemia. This research aims to determine the effect of giving papaya fruit to young women who suffer from anemia on increasing hemoglobin in the work area of the Jabi Village Community Health Center, Batam City in 2024. This research was conducted using the Pre-Experiment method using the One Group Pretest Posttest Design approach. The sample for this research was 16 young women. The results of this study showed that the majority of young women experienced moderate anemia, as many as 10 young women (62.5%). After giving papaya to young women for 10 days, it was found that the majority of young women were not anemic, as many as 10 young women (62.5%). Based on the results of the Paired Sample T Test statistical test, show that the p-value is 0.000 < 0.05, so it can be concluded that there is an effect of giving papaya fruit to young women who experience anemia on increasing hemoglobin in the working area of the Jabi Village Community Health Center, Batam City in 2024. It is hoped that the Health workforce can minimize anemia in young women by giving them papaya.

Background: Pregnant women with poor nutritional status are at risk of experiencing low breast milk production, which in turn can affect the fulfillment of infant nutrition from an early age. Suboptimal breast milk production impacts the growth and development of infants and has the potential to increase the incidence of malnutrition. Based on preliminary data in the Siti Hajar Room of Sultan Hadlirin Islamic Hospital, Jepara, it was found that several postpartum mothers experienced delayed breast milk production with a history of malnutrition. This condition shows the importance of maternal nutritional status during pregnancy as a factor that directly influences lactation. Objective: This study aims to determine the relationship between the nutritional status of pregnant women and postpartum breast milk production in the Siti Hajar Room of Sultan Hadlirin Islamic Hospital, Jepara. Method: The study used a cross-sectional design with a total sampling technique. A total of 30 postpartum mothers were selected as respondents. The independent variable consisted of the nutritional status of pregnant women as measured by Body Mass Index (BMI), Upper Arm Circumference (LILA), and hemoglobin (Hb) levels. The dependent variable was postpartum breast milk production as observed clinically. Data analysis was performed using the Chi-Square test with a significance level of p < 0.05. Results: The results of the study showed a significant relationship between the nutritional status of pregnant women and breast milk production. Statistical tests found that BMI (p = 0.018), LiLA (p = 0.027), and Hb levels (p = 0.006) had a significant association with the adequacy of breast milk production. Conclusion: The nutritional status of pregnant women was proven to be closely related to postpartum breast milk production. Mothers with good nutritional status tend to produce sufficient breast milk production. This finding emphasizes the need for routine nutritional monitoring of pregnant women and nutritional education during pregnancy to support the success of exclusive breastfeeding.

Background: Anemia is one of the public health problems commonly found among adolescent girls, especially in developing countries like Indonesia. This condition affects concentration, academic performance, and productivity, making early detection an essential step to prevent long-term complications. Objective: This study aims to determine the results of early detection of anemia based on clinical symptoms and hemoglobin (Hb) levels among adolescent girls at SMPN 18 Palembang. Methods: This research used a descriptive design with a cross-sectional approach. A total of 132 seventh-grade female students were selected randomly. Data were collected through an anemia symptom questionnaire and hemoglobin level measurement using a hemoglobinometer. Results: The study found that 23.5% of respondents were anemic (Hb < 12 g/dL), and 48.5% showed symptoms of anemia. However, the sensitivity of symptoms in detecting anemia was only 39%, specificity was 19%, with a positive predictive value (PPV) of 60.93% and a negative predictive value (NPV) of 8.82%. Conclusion: Based on the findings, symptom-based detection alone is not sufficiently accurate to diagnose anemia. Hemoglobin level examination is still required as a more valid and objective screening method for the early detection of anemia in adolescent girls In addition to medical intervention, the study advocates for increased awareness and education about anemia, its causes, and prevention methods among students, parents, and educators. Addressing nutritional deficiencies, especially iron intake, through dietary improvements and supplementation is essential in combating anemia in adolescent girls.

Anemia is a global health problem affecting approximately 30% of adolescents worldwide, with the highest prevalence among women aged 15-49. In Indonesia, data from the Ministry of Health in 2019 showed that the prevalence of anemia in adolescent girls reached 32%, with cases higher than in adolescent boys (27.2% vs. 20.3%). Anemia in adolescent girls negatively impacts growth, increases susceptibility to infection, and affects concentration and academic performance. Research Methods This study aims to evaluate the effectiveness of pandan leaves (Pandanus amaryllifolius Roxb.) as a dietary intervention to control anemia in adolescent girls. This quantitative study used a pre-experimental one-group pretest-posttest design with 19 adolescent girls from MA Bahrul Ulum Lamongan. The sample was selected using a purposive sampling technique. Respondents consumed 100 grams of pandan leaf pudding daily for seven days. The results of statistical analysis using the Paired Samples T-Test showed that there was a significant difference in hemoglobin levels (p <0.05) in respondents before and after consuming pandan leaf pudding. These results indicate that consuming pandan leaf pudding is effective in increasing hemoglobin levels in the study group.

Vitamin A Deficiency (VAD) and iron deficiency anemia (IDA) are global nutritional issues affecting children, particularly in developing countries. The interaction between these two conditions can lead to a more complex condition known as Vitamin A Deficiency Anemia (VADA). This study aims to review the molecular relationship between Vitamin A deficiency and iron metabolism leading to VADA, as well as its impact on children's health. The methodology used in this article is a literature review of various clinical studies, epidemiological research, and relevant molecular experiments. The results show that VADA is primarily a functional iron deficiency, where iron absorption is impaired despite overall body iron levels not being critically low. This mechanism involves the regulation of hepcidin, redistribution of iron, and its effects on erythropoiesis. Additionally, therapy with Vitamin A supplementation has been shown to increase erythropoietin and hemoglobin production in children with dual deficiencies. The implications of these findings highlight the need for more integrated therapeutic strategies that consider both Vitamin A and iron status simultaneously. Further research is needed to understand the molecular mechanisms more deeply involved in this interaction and to develop more effective therapies for children with VADA.

Anemia is a medical condition characterized by a lower-than-normal number of red blood cells or hemoglobin levels in the blood. This results in a reduced ability of the blood to carry oxygen throughout the body. Consequently, individuals with anemia may experience various symptoms such as fatigue, dizziness, and shortness of breath. The main causes of anemia are generally due to a lack of knowledge about this condition and deficiencies in nutrients such as iron.The purpose of this study is to determine the level of knowledge among ninth-grade female students regarding the prevention of anemia and their ability to prevent it. This study uses a descriptive research method, focusing on describing the level of knowledge of ninth-grade female students about the prevention of anemia.The study uses the Total Sampling method as the sampling technique, which means that all members of the population are included as respondents. Therefore, the number of respondents in this study is equal to the total population of female students, which are 54 individuals. Data collection is conducted using a closed-ended questionnaire consisting of 20 items covering indicators such as the definition of anemia, its etiology, signs and symptoms, treatment, and prevention.The results of the study show that knowledge regarding the definition of anemia is in the good category for 35 respondents (64.8%), knowledge about etiology is in the fair category for 35 respondents (64.8%), knowledge of signs and symptoms was in the fair category for 45 respondents (83.3%), knowledge about treatment is in the good category for 33 respondents (61.1%), and knowledge of prevention is in the fair category for 32 respondents (59.3%).It is hoped that by increasing the knowledge of ninth-grade female students about the prevention of anemia, schools and health workers can work together to carry out regular health education.

Pregnancy is a unique natural condition because although it is not a disease, it often causes complications due to various anatomical and physiological changes in the mother's body. Pregnant women who suffer from anemia can have an impact on the fetus, such as premature birth, the risk of low birth weight (LBW), fetal abnormalities, and increased risk of fetal distress. In general, the causes of anemia in pregnancy are iron deficiency and acute bleeding or even the interaction of both. The purpose of this study was to determine the difference in the effectiveness of giving red spinach juice and Ambon bananas on Hb levels in pregnant women in the third trimester. The design used in this study was a quantitative inferential study including the pre-experimental type with two group pretest-posttest. Based on the time of data collection, it included the cross-sectional type, sourced from primary and secondary data. An assessment of the difference in increasing HB levels was carried out before and after treatment (Pretest and Postest two Group Design). Data analysis consisted of univariate and bivariate analysis. The results of the analysis showed an effect in giving red spinach juice and Ambon bananas. It is hoped that the Health Center will facilitate health workers (midwives) in providing information on providing guava juice with red spinach leaf juice as an alternative for preventing and managing anemia during pregnancy in the Health Center's work area.    

Working memory capacity is a crucial aspect of cognitive function that plays a significant role in supporting students' learning processes. Working memory functions as a temporary storage system that allows individuals to store and manipulate information quickly. In an educational context, optimal working memory capacity can improve students' ability to understand, process, and remember information presented during the teaching and learning process. Several factors known to influence working memory capacity include breakfast habits, nutritional status, body fat percentage, and hemoglobin (Hb) levels. These factors are closely related to students' daily nutritional intake and healthy lifestyle. This Community Service (PkM) activity, with the topic "Healthy Food and Lifestyle to Increase Working Memory Capacity," aimed to increase students' understanding and awareness of the importance of a healthy diet and an active lifestyle in supporting cognitive function, particularly working memory. This activity was held in July 2024 at MTs (Madrasah Tsanawiyah) Al Fatah, Natar District, Lampung Regency. The implementation method was interactive nutrition education, covering the importance of a nutritious breakfast, consuming a balanced diet, physical activity, and general health care. Based on the results of evaluations conducted before and after the activity, there was an increase in the average knowledge scores of female students, as well as a significant difference in their understanding of the concepts of healthy eating and a lifestyle that supports working memory function. These findings indicate that nutrition education interventions have significant potential to improve the quality of learning by enhancing students' cognitive aspects. This activity is expected to become a model that can be implemented sustainably in other school settings.

Thalassemia is a genetic disorder characterized by impaired hemoglobin synthesis. This disease is caused by mutations in the globin gene, leading to disrupted production of globin chains. As a result, the red blood cells produced are dysfunctional and have a shorter lifespan, causing anemia. This condition requires proper medical management, including blood transfusions and other treatments. One way to detect and monitor the progression of thalassemia is by using biochemical markers that can identify changes in the patient’s body. Therefore, the aim of this systematic literature review is to identify biochemical markers that can be used for the diagnosis and monitoring of thalassemia. The literature used in this study includes articles on human thalassemia research published in the last 10 years. Literature searches were conducted in several academic databases using relevant keywords such as “biochemical markers for thalassemia,” “diagnosis of thalassemia,” and “thalassemia monitoring.” Based on the search results, several biochemical markers related to thalassemia were identified, including hepcidin, ferritin, and lipid profile. Ferritin plays a role in monitoring iron levels, which are often elevated in thalassemia patients, while hepcidin regulates iron homeostasis in the body. Additionally, other components involved in thalassemia diagnosis and monitoring include Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), and hemoglobin levels. The findings of this systematic literature review are expected to provide a comprehensive overview of biochemical markers that can be used in the diagnosis and monitoring of thalassemia. By identifying relevant markers, it is hoped that more accurate and effective diagnostic methods will be developed in the future, leading to better monitoring of thalassemia patients.

Background: Anemia during pregnancy remains a major public health concern in Indonesia, contributing to increased maternal and fetal morbidity. Iron supplementation often faces challenges in compliance and side effects, prompting the need for natural alternatives. Natural honey has been shown to help increase hemoglobin levels due to its iron, folate, and antioxidant content. Objective: This community service aimed to educate pregnant women on the benefits and utilization of natural honey as a complementary strategy to prevent anemia. Method: The activity was conducted at PMB CH Mala in Palembang City using health education sessions, demonstrations, and distribution of printed educational materials. Participants' knowledge and hemoglobin levels were assessed pre- and post-intervention using a questionnaire and digital hemoglobinometer. The intervention lasted for 2 weeks, with honey consumption recommended at 2 tablespoons daily. Results: There was a notable improvement in participants' knowledge about anemia and the role of honey. Preliminary observations also showed a slight increase in hemoglobin levels among pregnant women who regularly consumed honey during the intervention period. Conclusion: Educational intervention on the use of natural honey proved effective in improving knowledge and potentially supporting anemia prevention among pregnant women. Further studies are recommended to evaluate long-term outcomes and larger-scale implementation.

Chronic Kidney Disease (CKD) is a major global health issue that can lead to serious complications and long-term medical care. This study aims to identify key clinical factors associated with CKD status using binary logistic regression analysis. The dataset, obtained from Kaggle, contains 400 patient records with various clinical and demographic attributes. The dependent variable is CKD status (positive or negative), while the independent variables include age, blood pressure, hemoglobin level, urine albumin level, and serum creatinine. Initial analysis involved descriptive statistics and multicollinearity checks, followed by model estimation and evaluation using likelihood ratio and Wald tests. The final model identified four significant predictors: blood pressure, hemoglobin, urine albumin, and serum creatinine. The model achieved a high classification accuracy of 95.50% and an Area Under the ROC Curve (AUC) of 98.78%, indicating excellent predictive performance. These results highlight the importance of these clinical indicators in early CKD detection and support their use in risk assessment models for kidney disease screening Keywords: Chronic Kidney Disease, Binary Logistic Regression, Likelihood Ratio Test, Wald Test, Classification Accuracy

Iron-deficiency anemia during pregnancy remains a major public health concern in developing countries. This study aims to evaluate the effectiveness of iron and folic acid supplementation, known as iron tablets, in reducing the risk of anemia among pregnant women. A descriptive qualitative literature review method was employed by analyzing nine eligible studies published between 2013 and 2023. Articles were selected from databases including Google Scholar, PubMed, and ScienceDirect using specific keywords. The findings suggest that regular consumption of iron tablets, particularly starting in the second trimester and meeting the minimum recommended dose of 90 tablets, is effective in improving hemoglobin levels and lowering anemia prevalence. However, compliance remains a significant challenge, influenced by side effects, maternal knowledge, and social support. The review highlights the need for behavior-based interventions and family involvement to enhance adherence. The implication of this review supports the integration of targeted health education and follow-up strategies within antenatal care services to reduce anemia-related risks in pregnancy.

Type 2 diabetes mellitus (T2DM), hypertension, anemia, nephrotic syndrome, and urinary tract infection (UTI) are interrelated clinical conditions frequently encountered in patients with chronic kidney disease (CKD). This case report presents a 33-year-old woman who was admitted with complaints of generalized weakness, accompanied by headache, generalized edema, and pruritus. Laboratory findings revealed hyperglycemia (>300 mg/dL), elevated blood pressure (210/120 mmHg), increased urea and creatinine levels, 2+ proteinuria, and microcytic hypochromic anemia (hemoglobin ranging from 7.9 to 9.9 g/dL). Urinalysis showed leukocyturia, hyaline casts, and bacteriuria. The patient was diagnosed with uncontrolled T2DM, hypertensive urgency, microcytic hypochromic anemia, nephrotic syndrome, and UTI. Management included basal-bolus insulin regimen, combined antihypertensive therapy, packed red cell transfusions, and supportive treatments. Throughout the hospitalization, improvements were observed in hemoglobin levels and blood pressure, although subjective symptoms such as fatigue and headache remained fluctuating. This case highlights the importance of comprehensive and multidisciplinary management in patients with complex multisystem chronic conditions to prevent complications and improve clinical outcomes.

Iron deficiency anemia (ADB) is anemia that arises due to reduced iron supply for erythropoiesis, due to empty iron stores (depleted iron stores) which ultimately results in reduced hemoglobin formation. This study aims to determine the effect of giving blood supplement tablets on HB levels in female students suffering from anemia at SMAN 1 Tambakboyo, Tuban Regency. The research design used a pre-experiment using a one group pre test post test approach, with a total sampling technique on a population of 34 female students suffering from anemia in class X and analyzed using the Wilcoxon test. The instruments in this research were Standard Operating Procedures (SOP), hemoglobin level observation sheets and Easy Touch GCU brand hemoglobin measuring equipment. The results of the study showed that the average HB level before 10.17 g/dl and after 15.46 g/dl given blood supplement tablets was normal. The results of the Wilcoxon test obtained a significant value of p=0.000 (p<0.05), which means that there was a significant difference in the HB levels of class X female students before and after being given blood supplement tablets. Health workers, especially in school health offices, should provide blood supplement tablets at the right time so that female students can take the blood supplement tablets regularly and finish them.