Interaksi Antara Defisiensi Vitamin A dan Anemia Defisiensi Zat Besi pada Anak : Perspektif Biomolekuler dan Patofisiologis

Andy Sulaiman Siregar ; Arfiany Marina Nasution ; Muhammad Natsir Ilvira
Jurnal Kesehatan dan Kedokteran 📅 2025 Vol 2, No 4 🔗 DOI: 10.62383/vimed.v2i4.2338
Abstract
Vitamin A Deficiency (VAD) and iron deficiency anemia (IDA) are global nutritional issues affecting children, particularly in developing countries. The interaction between these two conditions can lead to a more complex condition known as Vitamin A Deficiency Anemia (VADA). This study aims to review the molecular relationship between Vitamin A deficiency and iron metabolism leading to VADA, as well as its impact on children's health. The methodology used in this article is a literature review of various clinical studies, epidemiological research, and relevant molecular experiments. The results show that VADA is primarily a functional iron deficiency, where iron absorption is impaired despite overall body iron levels not being critically low. This mechanism involves the regulation of hepcidin, redistribution of iron, and its effects on erythropoiesis. Additionally, therapy with Vitamin A supplementation has been shown to increase erythropoietin and hemoglobin production in children with dual deficiencies. The implications of these findings highlight the need for more integrated therapeutic strategies that consider both Vitamin A and iron status simultaneously. Further research is needed to understand the molecular mechanisms more deeply involved in this interaction and to develop more effective therapies for children with VADA.
Keywords
Vitamin A Deficiency; Iron Deficiency Anemia; VADA; hepcidin; erythropoiesis Vitamin A supplementation
How to Cite

Andy Sulaiman Siregar, et al. (2025). Interaksi Antara Defisiensi Vitamin A dan Anemia Defisiensi Zat Besi pada Anak : Perspektif Biomolekuler dan Patofisiologis. Jurnal Kesehatan dan Kedokteran, 2(4). https://doi.org/10.62383/vimed.v2i4.2338

Andy Sulaiman Siregar; Arfiany Marina Nasution; Muhammad Natsir Ilvira, "Interaksi Antara Defisiensi Vitamin A dan Anemia Defisiensi Zat Besi pada Anak : Perspektif Biomolekuler dan Patofisiologis," Jurnal Kesehatan dan Kedokteran, vol. 2, no. 4, 2025.

Andy Sulaiman Siregar; Arfiany Marina Nasution; Muhammad Natsir Ilvira. "Interaksi Antara Defisiensi Vitamin A dan Anemia Defisiensi Zat Besi pada Anak : Perspektif Biomolekuler dan Patofisiologis." Jurnal Kesehatan dan Kedokteran, vol. 2, no. 4, 2025.

Andy Sulaiman Siregar; Arfiany Marina Nasution; Muhammad Natsir Ilvira. "Interaksi Antara Defisiensi Vitamin A dan Anemia Defisiensi Zat Besi pada Anak : Perspektif Biomolekuler dan Patofisiologis." Jurnal Kesehatan dan Kedokteran 2, no. 4 (2025).

Andy Sulaiman Siregar, et al. (2025) 'Interaksi Antara Defisiensi Vitamin A dan Anemia Defisiensi Zat Besi pada Anak : Perspektif Biomolekuler dan Patofisiologis', Jurnal Kesehatan dan Kedokteran, 2(4). doi: 10.62383/vimed.v2i4.2338.

Andy Sulaiman Siregar; Arfiany Marina Nasution; Muhammad Natsir Ilvira. Interaksi Antara Defisiensi Vitamin A dan Anemia Defisiensi Zat Besi pada Anak : Perspektif Biomolekuler dan Patofisiologis. Jurnal Kesehatan dan Kedokteran. 2025;2(4).

Artikel Terkait

Diabetes Melitus Tipe 2

Dei Anjelia Nisa Br Ginting

Ventrikel Septum Defek (VSD) & Eisenmenger Syndrome

Muhammad Akil

Gambaran Tingkat Pengetahuan Bantuan Hidup Dasar (BHD) Tenaga Kesehatan di Puskesmas Lhoksukon

Tata Azzalia Khairan; Anna Millizia; Adi Rizka

Hubungan Asupan Magnesium dan Rasio Lingkar Pinggang Panggul (RLPP) dengan Kejadian Dismenore pada Remaja Putri di Kecamatan Tambakboyo

Susinta Melida; Dian Ayu Ainun Nafies

Hubungan Karakteristik Pasien Kolelitiasis terhadap Lamanya Perawatan di Rumah Sakit Umum Cut Meutia

Muhammad Nawawi; Muhammad Sayuti; Adi Rizka

Degradation of Pesticide Residues Cherizeb and Emacel in Chili Washing Water using ZnO/Zeolite Catalyst through Photolysis

Zilfa, Zilfa; Safni, Safni; Benny Damas Putra
Tren Sitasi Jurnal