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Diabetes mellitus is a chronic disease that requires long-term pharmacological therapy, increasing the risk of Drug Related Problems (DRPs). DRPs can affect the success of therapy, increase the risk of complications, and reduce the patient's quality of life. This article aims to identify the use of antidiabetic drugs, the characteristics of DRPs, and their clinical implications. The method used was a literature review of articles from 2016-2026 that are relevant to the analysis of DRPs in diabetes mellitus patients. The results of the study indicate that metformin is the most widely used antidiabetic drug, both as a single therapy and in combination. The dominant types of DRPs include drug interactions, inappropriate drug selection, inappropriate dosages, omissions from therapy, and use of drugs without indications. These DRPs can cause hypoglycemia, failure to achieve glycemic control targets, an increased risk of complications, and increased duration and cost of treatment. Based on the results of the study, it is concluded that DRPs remain a challenge in the management of diabetes mellitus therapy, requiring more optimal monitoring and an active role of pharmacists through medication review to improve the safety, effectiveness, and quality of treatment.

This study aims to analyze the influence of organizational culture and leadership on work discipline in employees of the Woja District Office, both partially and simultaneously. Using a saturated sample, all employees in the agency were directly involved as respondents as many as 45 respondents. Primary data were collected through a structured questionnaire and analyzed using multiple linear regression analysis techniques. The results of the study showed that partially, organizational culture had a positive and significant effect on employee work discipline, while leadership did not have a significant influence independently. However, simultaneous testing proves that organizational culture and leadership together have a positive and significant influence on shaping employee work discipline. These findings indicate that although personal leadership style is not the primary determinant of discipline that has been bound by bureaucratic regulations, the synergy between internalizing strong work culture values and leadership support remains an important combination for an orderly work ecosystem. This research provides practical implications for government organizations in strengthening work culture, increasing leadership effectiveness, and creating a work environment that is able to encourage employee compliance, responsibility, and productivity in a sustainable manner.

This study aims to analyze the effectiveness, contribution, and optimization strategies of Restaurant Tax and Hotel Tax in supporting the sustainability of Local Own-Source Revenue (PAD) of Bogor City. The study employed a descriptive method with a quantitative approach supported by qualitative data. The results indicate that the effectiveness levels of Restaurant Tax and Hotel Tax in Bogor City were categorized as highly effective, with average effectiveness ratios of 107.24%, and 117.74%, respectively. However, the contribution of Restaurant Tax to Local Own-Source Revenue was only 13.55%, which falls into the less contributive category, while the contribution of Hotel Tax was 8.03%, categorized as very low contributive. Based on the SWOT analysis, the reccomended optimization strategies include expanding the tax base through taxpayer data collection and updating, optimizing digital-based payment and monitoring systems, enhancing human resource capacity, strenghening tax education and outreach programs, developing risk based supervision, and improving inter agency cooperation. The implementation of these strategies is expected to increase the revenue and contribution of Restaurant Tax and Hotel Tax in supporting the sustainability of Bogor City’s Local Own-Source Revenue.

This study aims to analyze in depth the extent of the influence of content marketing and hedonic motivation on impulse buying in TikTok users, especially STIE Yapis Dompu students. This research illustrates a quantitative approach. The population of this study is all students who actively use the Tiktok Shop at STIE Yapis Dompu, the exact number of which is unknown. The number of samples used was 150. Non-probability sampling technique using the purposive sampling method. The data analysis in this study uses PLS-SEM Analysis. The results of the study showed that content marketing had a positive and significant effect on impulse buying, as evidenced by a t-statistical value of 3,116 > 1.96, and a p-value of 0.002 < 0.05. And hedonic motivation had a positive and significant effect on impulse buying, which was evidenced by a t-statistical value of 6,472 > 1.96, as well as a p-value 0.000 < 0.005. While the content marketing variable for hedonic motivation has a t-statistical value of 5,799 > 1.96, and a p-value of 0.000 < 0.05, content marketing has a positive and significant effect on hedonic motivation in STIE Yapis Dompu students.

This study analyzed the effectiveness and contribution of the Food and/or Beverage Tax, Hotel Services Tax, and Art and Entertainment Services Tax to Jakarta's Regional Own-Source Revenue during 2018–2024, and formulated policy recommendations based on fishbone (Ishikawa) analysis for the lowest-performing tax type. A descriptive quantitative approach supported by qualitative analysis was employed. Secondary data were obtained from Regional Government Financial Reports, while primary data were gathered through in-depth interviews with the Regional Revenue Agency, a tax consultant, an event organizer, and a venue operator. The Hotel Services Tax recorded the highest average effectiveness at 108.25%, followed by the Food and/or Beverage Tax at 100.72%, and the Art and Entertainment Services Tax at 98.88%. All three fell under the very low contribution category, with the Art and Entertainment Services Tax recording the lowest average at 1.16%. Fishbone analysis identified six root cause categories: disproportionate staffing and insufficient socialization (Man), reactive collection mechanisms (Method), limited tax technology implementation (Machine), misclassified business data and weak regulatory dissemination (Material), underreported revenues and high tax rates suppressing voluntary compliance (Measurement), and high entertainment sector elasticity with slow post-pandemic recovery (Environment). Policy recommendations were formulated across all six factors to optimize regional tax revenue.

Tomato (Solanum lycopersicum) is an economically important crop whose productivity is increasingly constrained by drought stress under changing climatic conditions. Conventional breeding for drought tolerance is often slow because this trait is quantitatively inherited and strongly influenced by environmental factors. Molecular markers, particularly Simple Sequence Repeats (SSRs), have become valuable tools for improving selection efficiency and accelerating breeding progress. This review examines the role of SSR markers in the development of drought-tolerant tomato cultivars. The physiological, biochemical, and molecular responses of tomato to drought stress, including growth reduction, photosynthetic impairment, osmotic adjustment, hormonal regulation, and oxidative stress responses, are briefly discussed. The genetic characteristics of SSR markers, including their high polymorphism, co-dominant inheritance, and multi-allelic nature, are highlighted as key advantages for genetic analysis and breeding applications. Furthermore, the review synthesizes recent findings on the use of SSR markers for genetic diversity assessment, Quantitative Trait Loci (QTL) mapping, and identification of genomic regions associated with drought-related traits such as relative water content, chlorophyll stability, root architecture, and proline accumulation. The application of SSRs in Marker-Assisted Selection (MAS), including marker-assisted backcrossing and QTL pyramiding, is also discussed. Finally, the review evaluates the continuing relevance of SSR markers in the genomic era, emphasizing their complementary role alongside Single Nucleotide Polymorphism (SNP) markers, Genome-Wide Association Studies (GWAS), and Genomic Selection (GS). Integrating SSR-based approaches with modern genomic tools offers a promising strategy for developing climate-resilient tomato cultivars and enhancing future food security.

As a strategic public policy, the Free Nutritious Meal program serves as a long-term social investment aimed at enhancing the quality of human resources. This study is directed to examine and map the positive contributions of the MBG initiative to the pillars of health, discipline levels, and academic achievement of students through a literature review method. The article search, utilizing keywords such as "Makan Bergizi Gratis," "Implementasi MBG," and "Dampak MBG," yielded 10 relevant scientific articles, which were subsequently analyzed using thematic analysis techniques. The findings indicate that the MBG program exerts a significant positive impact on various dimensions of student development. In the academic aspect, this program improves students' focus, concentration, motivation, and active learning engagement. Health-wise, MBG contributes to improving nutritional status, which supports children's physical and psychological readiness, whereas, in terms of discipline, this intervention is proven to increase attendance rates while reducing tardiness at school. Overall, it is concluded that the MBG program does not merely function to fulfill essential nutritional intake, but also acts to maximize learning effectiveness and student academic performance across all education levels.

The purpose of this study was to focus on the development and feasibility testing of the Ekorama Pop-Up Book as a learning medium, as well as to assess its practicality and effectiveness in helping fifth-grade elementary school students master science concepts related to food chains. Research and Development (R&D) using the ADDIE model—which begins with analysis and ends with evaluation—will be applied in this study. The participants include media and content experts, teachers, and 19 fifth-grade students at MIN 8 in Medan. Data were collected using response questionnaires, concept comprehension tests, and validation sheets. The results of the expert validation indicated that the category was highly valid, highly practical (96.7%), and highly effective (N-Gain = 0.87), as evidenced by the test results showing an increase in students’ understanding. In other words, the Ekorama Pop-Up Book was deemed suitable as a science learning medium for improving conceptual understanding among elementary school students.

Pelanggaran jam operasional kendaraan bertonase besar di kawasan Simpang Patal Kota Palembang masih sering terjadi dan menyebabkan kemacetan, risiko kecelakaan, serta kerusakan jalan. Penelitian ini bertujuan menganalisis alternatif kebijakan yang paling tepat untuk penertiban mobil barang di kawasan tersebut. Penelitian menggunakan metode deskriptif kualitatif melalui observasi, wawancara, dokumentasi, dan studi literatur. Analisis data dilakukan menggunakan model Miles dan Huberman, sedangkan evaluasi kebijakan menggunakan pendekatan Multi-Criteria Decision Analysis (MCDA) berdasarkan kriteria William N. Dunn. Terdapat tiga alternatif kebijakan yang dianalisis, yaitu mempertahankan kebijakan yang berlaku (status quo), revisi Perwali Nomor 26 Tahun 2019 dan implementasi Electronic Traffic Law Enforcement (ETLE), serta penyediaan kantong parkir (holding area) di kawasan Pelabuhan Sungai Lais. Hasil penelitian menunjukkan bahwa alternatif penyediaan kantong parkir (holding area) memperoleh skor tertinggi sebesar 91 dengan rata-rata 4,55 sehingga dinilai paling optimal dalam mengurangi pelanggaran, kemacetan, dan risiko kecelakaan serta mendukung transportasi perkotaan yang lebih tertib dan berkelanjutan.

Musi Rawas Utara Regency is categorized as an underdeveloped, frontier, and outermost (3T) region that still faces serious challenges in human development, particularly within the education dimension. Although the Human Development Index (HDI) indicates an upward trend, the School Enrollment Rate (SER) and the mean years of schooling at the secondary education level remain relatively low and lag behind other regions. This condition is influenced by limited access to secondary education, household economic vulnerability, and disparities in the quality and distribution of educators in remote areas. This policy paper aims to analyze secondary education issues as a primary obstacle to increasing the HDI of Musi Rawas Utara Regency and to formulate effective and sustainable policy alternatives. The method used is a qualitative descriptive analysis through a literature study, utilizing data from the Central Bureau of Statistics (BPS), regional planning documents, as well as relevant national regulations and policies. The analysis was conducted using a SWOT approach to identify the strengths, weaknesses, opportunities, and threats of the regional education policy. The results of the study show that improving the HDI requires integrated, affirmative, and region-based education policies. Three main policy alternatives recommended include expanding and equalizing access to secondary education, strengthening educational assistance and social protection for vulnerable families, and sustainably distributing and improving teacher quality. The implementation of these policies is expected to increase the SER, extend the mean years of schooling, and strengthen the quality of human resources as a foundation for sustainable development in Musi Rawas Utara Regency.

Cultural values are life principles that guide Javanese society in acting. This article aims to analyze how Javanese cultural values are contained in the novel Sumirat Ing Mripat. The approach used is a semiotic approach from the perspective of Rolland Barthes. The analytical method used is Rolland Barthes’ semiotic theory. This analytical method consists of denotation, connotation, and myth. The analysis is carried out by linking the results of the interpretation of signs to five cultural value relationships. The semiotic approach is used to reveal the meaning and signs of Javanese cultural values. The novel Sumirat Ing Mripat was taken as a data source in this study. The results show that the novel Sumirat Ing Mripat represents cultural values. These values are the value of rationality in the relationship between humans and themselves, the value of piety in the relationship between humans and God, the value of non-rationality in the relationship between humans and others, the value of harmony in the relationship between humans and nature, and the value of deliberation in the relationship between humans and society. This study confirms that literary works function as a representation of the system of Javanese cultural values.

The role of guidance and counseling teachers in student career planning in vocational schools is still weak. The purpose of the study was to analyze the implementation of the BK service program in career planning for vocational school students. The study used a qualitative descriptive method. The study was conducted at SMK Muhammadiyah Paguyangan with research subjects being BK teachers, vice principals for curriculum, and vocational school students. Data collection through observation, interviews, and document studies. Data validation applied triangulation of sources and methods. Data analysis used the Atlas ti.8 application. Research stages; determining topics, compiling interview guidelines, selecting data collection methods, collecting data, analyzing data, and drawing conclusions. Research results; (1) the role of BK teachers in identifying students' potential, interests, talents, providing guidance in choosing education or careers, as motivators, facilitators, mediators, directors, program managers, and informants, (2) BK teacher strategies in student career planning; providing basic services to recognize self-potential, motivating, encouraging the use of technology, and digital platforms, and (3) implementation of BK programs through an integrated process, including; program planning, resource provision, implementation of evaluation services, feedback, and continuous improvement. Program innovation and monitoring are integral parts to maintain the relevance and effectiveness of BK services. The success of BK program implementation depends on the quality of coordination and commitment of all parties in developing the program.

Pierhead casting is a critical activity in toll road infrastructure projects that requires continuous concrete supply to maintain quality and execution time. Factors influencing the smooth casting process include the regularity of truck mixer arrival intervals and the work cycle of the truck concrete pump. This study aims to analyze the effect of truck mixer intervals and truck concrete pump performance on the productivity of pierhead casting at Pierhead P37S on the Solo–Yogyakarta–NYIA Toll Road Project, Section 2 Package 2.1A. The analysis method used field observation through time study techniques to measure the cycle duration of truck mixers and the operating time of the truck concrete pump. The analysis stages included calculating cycle time, productivity, production capacity, and working duration of each equipment. The results show that the truck concrete pump achieved a productivity of 0.425 m³/minute, while the truck mixer reached 0.989 m³/minute. These values were influenced by cycle time, equipment condition, work area condition, execution method, and work volume. Based on duration analysis, the truck concrete pump required about 4.7 hours to complete the casting of 120 m³ of ready-mix concrete, while the truck mixer required 2.022 hours to support the concrete supply process.

Article 1 paragraph (3) of the 1945 Constitution of the Republic of Indonesia affirms Indonesia as a state based on law, yet in practice Indonesia's legal system faces a structural problem of hyperregulation and overregulation, characterized by massive regulatory proliferation and regulatory disharmony without adequate corrective mechanisms. This condition is likewise reflected in Semarang Regency, which has 673 active legal products with Regional Head Regulations dominating at 77.3%, while Regional Regulation No. 10 of 2021 on the Formation of Regional Legal Products has not yet accommodated a legal analysis and evaluation mechanism. This study aims to explore the urgency of regional regulatory reform through legal analysis and evaluation mechanisms and to construct an implementation model in Semarang Regency. This study employs a prescriptive socio-legal research method with an interdisciplinary approach. The findings indicate that this condition reflects the dominance of primary rules without adequate institutionalization of secondary rules within H.L.A. Hart's perspective, while simultaneously representing a dysfunction in legal substance with cyclical impacts on legal structure and legal culture according to Lawrence M. Friedman. Therefore, a regulatory governance-based analysis and evaluation model is needed, integrating the regulatory cycle from ex ante to ex post with multistakeholder coordination and evaluation grounded in BPHN's 6-dimension framework

This study examines the recurring traffic accidents at the Bawen intersection in Semarang Regency, particularly involving heavy vehicles descending from the toll exit. The research aims to analyze the underlying causes and formulate an effective accident prevention model. Using a qualitative empirical juridical approach, data were collected through field observations, interviews, and document analysis. The findings reveal that accidents are caused by a systemic interaction of factors, including inadequate road geometry, vehicle technical failures (especially brake malfunction), driver fatigue and limited competence, suboptimal traffic management, and weak preventive law enforcement. These interrelated factors create a high-risk traffic environment, particularly at signalized intersections at the end of steep descents. The study proposes an integrated prevention model combining infrastructure improvement, vehicle supervision, driver capacity enhancement, technology-based traffic management, and preventive law enforcement. This model emphasizes a holistic and sustainable approach to traffic safety. The implications highlight the need for coordinated policies among stakeholders to reduce accident rates and improve overall road safety in the region.

Semarang Regency holds a strategic geographical position as a transit hub along the Semarang–Solo–Yogyakarta corridor, supported by diverse tourist attractions and strong economic performance. Despite recording 744,659 domestic tourist movements in March 2026 based on Mobile Positioning Data, the regency failed to enter the top ten most-visited destinations in Central Java during the 2026 Lebaran holiday, with only 139,816 visits recorded at its ten leading attractions. This yields an indicative conversion rate of approximately 18.8 percent at the Lebaran peak, meaning more than 80 percent of movements passing through the regency did not translate into recorded tourism visits. This study employs a descriptive quantitative method supported by explanatory qualitative analysis (sequential explanatory mixed methods), triangulating four secondary data sources to identify the competitive gap, analyze conversion disparities, and formulate improvement strategies toward Lebaran 2027. Findings indicate that the primary drivers of low conversion are the transit-only behavior of the majority of visitors and accessibility constraints at the Bawen–Ambarawa–Bandungan corridor. The study recommends four priority strategies: integrated single-window digital data management via Application Programming Interface; private-vehicle-based traffic and access management; four anchor-themed festival clusters across 14 sub-districts; and the formalization of Pangsar Sudirman Night Market and Kuda Lumping Festival as official tourism events. Achieving the minimum target of 203,458 visits to enter the top ten requires an increase of at least 63,642 visits (approximately 45 percent above the current recorded baseline).

Lake Rawa Pening is one of Indonesia’s priority lakes facing serious ecological pressure due to the rapid proliferation of water hyacinth. This study aims to classify and map the distribution of water hyacinth in Rawa Pening Lake during the 2021–2025 period and to analyze the seasonal distribution patterns of water hyacinth. Sentinel-2 imagery processed on the Google Earth Engine platform was classified using the Random Forest algorithm combined with hybrid sampling and spectral indices (NDVI, NDWI, MNDWI, and SRI). Classification accuracy assessment showed high performance with an Overall Accuracy of 97.45% and a Kappa coefficient of 0.949. The results indicate significant spatial-temporal fluctuations, with the highest coverage recorded in March–April 2021 (855.75 ha) and the lowest in May–June 2022 (108.44 ha). Seasonal-Trend Decomposition using Loess (STL) revealed consistent seasonal patterns, with peak expansion occurring during the rainy season, particularly in January–February. Although initial implementation of lake management policies reduced coverage, subsequent increases suggest that control measures remain insufficiently sustainable. This study demonstrates the effectiveness of cloud-based satellite monitoring for evaluating lake management policies and supporting evidence-based environmental management strategies.

One of the key sectors driving regional economic growth which boosts local revenue, creates jobs, and fosters regional development is tourism. This study aims to analyze the state of human resources (HR) in the management of tourist attractions in Semarang Regency and to formulate strategies for their improvement. The method used is qualitative descriptive research through observation, interviews, and documentation, with analysis employing the Human Capital Index (HCI) and SWOT analysis. The results indicate that destination facilities are generally adequate, but service quality and the availability of information remain suboptimal. An HCI score of 2.84 (moderate category) indicates that HR capacity, competence, and development still need to be improved. Therefore, HR strengthening strategies are needed through capacity building, competency-based training, and performance management enhancement to improve service quality and destination competitiveness.

Mie basah bebas gluten umumnya memiliki kandungan protein yang relatif rendah karena didominasi oleh bahan berpati, sehingga diperlukan upaya peningkatan nilai gizi tanpa menurunkan tingkat penerimaan konsumen. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan tepung ikan teri medan (Stolephorus sp.) terhadap tingkat kesukaan mie basah bebas gluten serta mengetahui karakteristik kimia pada perlakuan terbaik. Penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan empat taraf penambahan tepung ikan teri medan, yaitu P0 (0 g), P1 (5 g), P2 (10 g), dan P3 (15 g). Tingkat kesukaan dinilai oleh 40 panelis pada parameter warna, aroma, rasa, dan tekstur menggunakan uji hedonik. Data dianalisis menggunakan Analysis of Variance (ANOVA) dan dilanjutkan dengan uji Duncan. Perlakuan terbaik ditentukan menggunakan metode indeks efektivitas dan selanjutnya dianalisis secara proksimat. Hasil penelitian menunjukkan bahwa penambahan tepung ikan teri medan berpengaruh terhadap tingkat kesukaan mie basah bebas gluten. Perlakuan terbaik diperoleh pada P1 (5 g) berdasarkan nilai indeks efektivitas tertinggi. Hasil analisis kimia pada P1 menunjukkan kadar air 37,33%, kadar abu 1,71%, kadar lemak 3,34%, kadar protein 9,76%, dan kadar karbohidrat 47,86%. Kadar protein telah memenuhi persyaratan mutu mie basah berdasarkan SNI 2987:2015, meskipun kadar air masih melebihi standar. Penambahan tepung ikan teri medan berpotensi meningkatkan nilai gizi mie basah bebas gluten dengan tetap mempertahankan tingkat penerimaan konsumen.

The School Participation Rate in Semarang Regency is high, yet the quality of human resources remains relatively poor. This study aims to identify the profile of students’ potential and constraints within the framework of Self-Regulated Learning, as well as to analyse the gap between the level of importance and the level of implementation in Semarang Regency. Data were collected via a Self-Regulated Learning questionnaire and analysed using the Importance–Performance Analysis (IPA) method. The results indicate an average importance score of 3.04 and an implementation score of 3.03, suggesting a gap, albeit a relatively small one. The distribution of indicators showed that 14 were in the high-priority category, 10 in the maintain category, 9 in the low-priority category, and 16 in the over-emphasised quadrant. These findings suggest that students are aware of the importance of learning strategies but have not yet been able to implement them optimally. Learning strategies are still dominated by basic, repetitive activities, whilst metacognitive skills and self-regulation have not yet developed optimally.