Aspartam adalah salah satu jenis pemanis buatan yang memiliki rasa 200 kali lebih manis dari pada sukrosa. Proses metabolisme aspartam dalam tubuh dapat menyebakan kerusakan pada ginjal. Salah satu senyawa yang memiliki potensi sebagai pelindung ginjal adalah jintan hitam karena mengandung senyawa antioksidan. Penelitian ini bertujuan untuk mengetahui efek nefroprotektif pemberian jintan hitam pada pengamatan makroskopis dan mikroskopis ginjal tikus putih yang diinduksi aspartam. Penelitian ini merupakan penelitian analitik eksperimental dengan menggunakan 5 kelompok perlakuan yaitu kelompok kontrol normal (K1), kelompok kontrol negatif (K2), kelompok pemberian aspartam dan jintan hitam dengan dosis 0,1 mL (K3), kelompok pemberian aspartam dan jintan hitam dengan dosis 0,2 mL (K4), serta kelompok pemberian aspartam dan jintan hitam dengan dosis 0,3 mL (K5). Hasil pengamatan makroskopis didapatkan hasil bahwa terdapat perbedaan warna ginjal dimana pada kelompok (K1), (K2), dan (K3) berwarna coklat kemerahan, sedangkan pada kelompok (K4) dan (K5) berwarna coklat tua, memiliki tekstur kenyal, dan memiliki ukuran yang berbeda tiap kelompok. Pada hasil pengamatan mikroskopis yang dianalisis menggunakan uji statistic One Way ANOVA didapatkan nilai signifikasi ? 0,05 yang artinya terdapat perbedaan yang bermakna rerata pada semua perlakuan. Berdasarkan uji lanjut Post Hoc Tukey didapatkan dosis jintan hitam yang paling efektif yang mampu memberikan efek nefroprotektif yaitu pada kelompok (K4) dengan dosis sebanyak 0,2 mL/200 g BB/hari.

The issuance of Minister of Trade Regulation Number 31 of 2023 concerning Business Licensing, Advertising, Guidance, and Supervision of Business Actors in Electronic Commerce is the Indonesian government's effort to regulate digital trading activities, including those conducted through social commerce platforms like TikTok Shop. This regulation aims to create a balanced trade ecosystem, ensure fair competition, and protect micro, small, and medium enterprises (MSMEs) in the midst of rapid technological advancements. However, the implementation of this regulation also raises challenges, particularly for MSME actors who rely on social commerce platforms as a marketplace. This paper aims to analyze the impact of the regulation on TikTok Shop and its implications for MSME development in Indonesia. The analysis is conducted by examining the content of the regulation and its effects on various stakeholders in the e-commerce ecosystem.

The GKSI Nazareth SP 5 congregation, which consists of various ages and social backgrounds, faces challenges in understanding and applying the true meaning of worship. Many congregations do not fully understand the essence of worship as a form of direct communication with God, but only carry it out as a routine ritual. With the increasing influence of technology and social media, priority for spiritual activities such as worship tends to decrease. The method used is qualitative by observing the phenomena that occur and continuing with data collection by taking notes, then conducting a literature search, journals, books and the Bible to support the research. Novelty lies in the church's approach to taking concrete steps to guide the congregation to understand the teachings of God's Word regarding worship. The findings show positive changes in the GKSI Nazareth SP 5 Congregation, explanations of guidance from God's Word and also explanations of the meaning of worship that the GKSI Nazareth SP 5 Congregation can apply in their lives. This positive change can be seen in the fact that they are willing to give up their time to come to worship together on Sundays and also to worship at home.

Organizational commitment in higher education institutions plays an important role in improving the quality of education. The demands and needs of society for the quality of education are aligned with organizational commitment. On the other hand, the merger of universities is also a strategic step in improving the quality of education. At this point, the merger of organizations can influence the work commitment of its employees, with various moderating factors. This study aims to describe how organizational commitment is, especially on post-merger period. By using 5 dimensions of organizational commitment, the differences in commitment in each group are tested quantitatively. Of the five dimensions of organizational commitment, namely: affective commitment, ongoing commitment (active), ongoing commitment (passive), normative commitment, and value commitment, there are significant differences in ongoing commitment (active) and values. The implication of this finding is that there is no common orientation towards career and shared values ​​after the merger.

This study investigates whether AI is a possible game-changer in the communications industry for cultural manifestations digitally and, hence, an active protagonist in the moisture preservation and sustenance of Nusantara cultural heritage. By examining eight cultural applications on the Google Playstore ranging from cultural education application to local language dictionary application and so on, this research evaluate the existing mobile apps and future opportunities for integrating AI into cultural preservation endeavors. The results indicate that present applications do not employ AI but there is great potential for incorporating AI features such as adaptive learning, semantic search, and personalization of content recommendations. The study stresses having a solid digital backbone defined by an inclusive policy framework and collaborative inter-disciplines which is crucial because of challenges such as disparities in technological access, data privacy concerns, and resistance from culture. Policy recommendations ensuring the responsible use of AI are put forward in terms of ethical standards, digital literacy, and sustainable development that strive to advance Indonesia's digitalization narratives in harmony with cultural sustainability in the wake of the digital era.

The management of regional finances aims to realize good governance that includes efficiency and transparency in meeting public needs. Efficiency and transparency in the decentralization of financial management policy by the Financial and Asset Management Agency (BKAD) of Kupang City are key factors in ensuring proper regional financial management. This study uses an empirical research method. After data collection, the researcher categorized the data based on the sources and analyzed them. The results of this study indicate that Efficiency has not been fully achieved due to mismatches in budget allocation. Meanwhile, transparency remains suboptimal because the existing system often experiences disruptions, limiting open access to information. The most dominant inhibiting factor affecting implementation effectiveness is human resources (HR). In addition, dependency on central government funding hampers flexibility and independence in regional financial management. The study suggests that BKAD should conduct technical competency training and development for staff, the Kupang City Government should increase local revenue (PAD), and the public should actively participate in budget public consultations.

Anemia in pregnant women is the main cause of bleeding and infection which is a major factor in maternal death. A woman who experiences bleeding after giving birth can suffer from severe blood deficiency (anemia) and experience long-term health problems. With a rate of 305 per 100,000 live births, Indonesia has a high maternal mortality rate (MMR) when compared to other ASEAN countries. The MMR target is 70 per 100,000 live births in 2030, in accordance with the Sustainable Development Goals (SDGs) (Sustainable Development Goals (SDGs), 2017; WHO, 2022). Currently, the rate of anemia in pregnant women is still high. Based on 2018 RISKESDAS data, the prevalence of anemia in pregnant women is 48.9%, meaning that 4-5 out of 10 pregnant women suffer from anemia. Maternal Mortality Rate (MMR) or Maternal Mortality Ratio (MMR) is an important indicator of the level of public health and is a sensitive indicator in describing the welfare of society in a country. . This research uses a cross-sectional strategy, using numerical data through a retrospective survey with a sample of 35 people. Research Results Based on the results of statistical tests, it was found that p.value = 0.003 and α = 0.05, where the P.value (0.003) < α (0.05) there is a relationship between maternal parity and the incidence of anemia. Based on the results of statistical tests, it was found that p.value = 0.005 and α = 0.05, where the P.value (0.005) < α (0.05), so it can be concluded that there is a relationship between maternal age and the incidence of anemia. Based on the results of statistical tests, it was found that p.value = 0.005 and α = 0.05, where the P.value (0.005) < α (0.05), so it can be concluded that there is a relationship between pregnancy spacing and the incidence of anemia. Based on the results of statistical tests, it was found that p.value = 0.005 and α = 0.05, where the value of P.value (0.005) < α (0.05), so it can be concluded that there is a SEZ status with anemia incidence

This study examines the legal aspects of land lease agreements for Madura grocery stalls based on Article 1548 of the Indonesian Civil Code. A normative juridical method is employed, focusing on statutory regulations and literature review. The primary focus is to identify essential elements in the lease agreement, such as the leased object, mutual consent, and payment obligations. The research also highlights breach of contract issues and emphasizes the importance of legal guarantees in lease relationships. Case studies and recent regulations support the findings, ultimately contributing to legal certainty in land lease practices within the MSME sector.

Narcotics are substances that cause certain effects for those who use them and put them into their bodies. Along with the development of the times, the types of drugs are increasing and have various variations. One example of a new type of drug is gorilla tobacco. Criminal Law Policy Against New Types of Narcotics Abuse. This study uses a normative juridical research type with a Philosophical approach, Criminal Law Political Approach, legislation, case approach and examines the contents of various legal sources, both books, journals and other related legal sources to answer the aspects that are the focus of the research. The results of this study indicate that in 2022 31,420 incidents were caused by an increase in the abuse of new types of narcotics (New Psychoactive Substances) which in previous years were not registered in the appendix to Law Number 35 of 2009, this caused a Legal Vacuum regarding the New Type of Narcotics. In addition, the author also analyzes the law enforcement against new types of narcotics (gorilla tobacco) in a review of Law Number 35 of 2009 concerning Narcotics and the form of criminal responsibility carried out by perpetrators of gorilla tobacco abuse in the decision of the District Court Number 32/Pid.sus/2021/PN Rtg.

Breast cancer (Ca Mammae) is a group of abnormal cells in the breast that continue to grow and multiply in the form of lumps in the breast. In the body there are millions of cells. One of them is abnormal cells or metaplasia cells, which are cells that can change but are still within normal limits. Breast cancer is not a very scary scourge for all women without exception teenagers. One way to detect breast anker is to do a breast self-examination, SADARI is an examination of the breast itself to find lumps in the breasts. Objective: This study aims to determine the Influence of Breast Self-Examination Health Education (SADARI) with Leaflet media on knowledge and attitudes about early detection of breast cancer in adolescent girls in class X at SMAN 16 Medan. Research Method: This study is a Quasy Experimental with the One Group Pretest-Post Test approach with a Proportional Stratified Random Sampling technique with a total of 52 samples. Results of the study: by using the wilcoxon test before and after the provision of health education, the SADARI examination obtained a p value = 0.000 (<0.05). The conclusion is that Ha was accepted and Ho was rejected because there was an influence of breast health education (SADARI) with leaflet media on knowledge and attitudes about early detection of breast cancer in adolescent girls in class X at SMAN 16 Medan.