The development of Artificial Intelligence (AI) technology has brought significant changes in digital marketing strategies, allowing businesses to increase efficiency, personalization, and market reach. This research aims to identify forms of AI use in digital marketing, analyse implementation challenges, and explore opportunities that can be maximized by business actors, mainly digital MSMEs in the city of Palembang. Using a descriptive qualitative approach, data were collected through literature studies and semi-structured interviews with business actors and digital marketing practitioners. The results show that AI has been utilized in various forms, such as chatbots, product recommendation systems, targeted advertising, predictive analytics, and content automation. However, its implementation still faces challenges, including low technology literacy, limited human resources, infrastructure costs, and data privacy issues. On the other hand, tremendous opportunities are opening up through personalizing consumer experience, operational efficiency, data-driven product development, and expanding the global digital market. This research is expected to make a theoretical contribution to the development of technology-based marketing literature and become a practical reference for business actors in utilizing AI strategically and sustainably.
 

The school productivity of each institution needs to be considered in order to create optimal graduate results. School productivity needs to be considered because it affects the growth and development of the institution. Therefore, this study was conducted where in the observation there were problems, especially at the Integrated Islamic Elementary School in Klari District, Karawang. The research method used is descriptive method and verification method. Population of 240 teachers, sample of 150 teachers, Non Probability sampling technique, based on sample provisions by Slovin, data collection technique questionnaire "Likert scale" and data processing technique path analysis and using SPSS version 25 application. Teacher competency variables can be stated in the category of good enough and running optimally, organizational culture variables can be stated in the category of good enough and so is the motivation variable is in the category of good enough and has an effect on school productivity in integrated Islamic elementary schools in Klari District, Karawang. Teacher competency, organizational culture and motivation have a significant relationship. Teacher competency on school productivity also has a greater influence. This study aims to determine how much influence teacher competence have on school productivity at the Integrated Islamic Elementary School in Klari District, Karawang. This study was conducted at the Integrated Islamic Elementary School in Klari District, Karawang.

The Dayak Sanggau community practices a number of cultural traditions during pregnancy, childbirth, and the postpartum period, reflecting a blend of spiritual beliefs and medical needs. This study employed a qualitative method with a literature review (library research) approach to explore pregnancy, childbirth, and postpartum practices among the Dayak Sanggau people. The findings identified supportive practices such as spousal involvement and basic check-ups by traditional midwives, as well as potentially harmful practices including non-sterile vaginal examinations, childbirth in the kitchen area, and the use of alcoholic herbal concoctions for infants. The conclusion emphasizes the importance of understanding local culture and integrating medical education so that positive traditional practices can be preserved, while risky ones are minimized through culturally sensitive interventions.

Abstract. Background: Slimming drugs, such as phentermine, are widely used for weight reduction but are known to induce oxidative stress, particularly affecting hepatic and renal tissues. Selenium nanoparticles (SeNPs), especially those biosynthesized using natural sources like spirulina platensis, have demonstrated promising antioxidant and protective activities in biological systems.
Objective: This study aimed to assess the protective effects of selenium nanoparticles synthesized from spirulina platensis extract on renal and hepatic functions in male rats exposed to phentermine induced oxidative stress.
Methods: Twenty-six adult male wistar rats were divided into five experimental groups: control group (dosed with water n=5), SeNPs group (dosed with SeNPs n=5), phentermine group (dosed with phentermine n=5), SeNPs then phentermine group (dosed with SeNPs then phentermine n=5), phentermine then SeNPs group (dosed with phentermine then SeNPs n=5). The experiment lasted for 45 days, the measurement of cytokines IL-6, IL-12, TOS and TO-AC.
Results: Phentermine administration significantly increased cytokines IL-6, IL-12 indicating marked oxidative stress and immune activation. Treatment with SeNPs alone or in combination with phentermine notably improved these parameters. The group dosed with SeNPs prior to phentermine (SeNPs then phentermine) showed the most prominent protective effects with values approaching those of the control.
Conclusions: Selenium nanoparticles from spirulina platensis demonstrated significant protective, antioxidant, and immunomodulatory effects against phentermine induced immune disturbances. These findings support their potential

This study aims to analyze the importance of building trust and mutual understanding among organizational members to enhance team performance and work effectiveness at Greet Bear Bowl Restaurant. Trust is developed through open communication, organizational justice, and recognition of individual contributions. Meanwhile, mutual understanding is supported by active participation, aligned goals, and a positive organizational culture. The study adopts a qualitative approach using in-depth interviews with four permanent employees. The results indicate that trust and understanding play a crucial role in strengthening work relationships, improving coordination, and supporting the effective and sustainable achievement of organizational goals.

Several of the best-selling small-molecule medications and natural alkaloids contain piperidine, a crucial saturated heterocyclic scaffold with a wide variety of biological functions. The hydrazide-hydrazone moiety's exceptional use in the pharmacological and biological domains made it particularly appealing. Objective: Designing and synthesizing a novel set of 4-Piperidin-1-yl-benzoic acid substituted hydrazides, Ac1-c3 and Bc1-c5, as potentially antimicrobial agents and characterizing them using IR, 1H-NMR, and mass spectroscopy. Methods: By esterifying 4- Piperidin-1-yl-benzoic acid Ac1 and then treating with hydrazine hydrate it to produce Ac3 in a good yield. The hydrazide Ac3 was condensed with the proper aldehydes or ketone to synthesis the hydrazones Bc1–c5. The in vitro bacterial activity was evaluated anti two Gram-negative bacteria, Pseudomonas aeruginosa, and Candida albicans, as well as two Gram-positive bacteria, Staphylococcus aureus and Bacillus subtilis. Results: The majority of tested compounds demonstrated significant efficacy anti Pseudomonas aeruginosa, Candida albicans. Notably, compound Bc3 emerged as the most effective derivative within the series. Conclusions: The Compounds (Bc1–c4) that were synthesized demonstrated moderate to good antimicrobial activity against a number of bacterias species and Candida albicans.

This research is motivated by the difficulties experienced by students in imagining and composing fantasy stories. To overcome this, a Flipbook-based e-module was developed for the Indonesian Language subject with fantasy story text material containing elements of critical reasoning to train students' critical reasoning skills. The purpose of this research is to develop digital learning media that facilitates the learning process. The research uses the ADDIE development model (analysis, design, development, implementation, evaluation). This research was conducted at Puspita Middle School with 39 students of class VII-G as research subjects. Data were collected through observation, interviews, and questionnaires to students, educators, media experts and material experts to assess the feasibility of the e-module. The results showed that the e-module was declared valid and practical to use, with an assessment from media experts of 86.67%, material experts 98.67%, indicating a statement that it was very appropriate without revision, and an assessment from Indonesian Language teachers of 94.67%, and student responses of 96.14%. Thus, the e-module of fantasy story texts containing critical reasoning based on flipbooks gets a very good and very decent category.
 

The emergence of fintech services requires banks to enhance their competitive advantage through technological innovation and digitalization, compelling Rural Banks (BPR) to adapt in order to remain relevant in an increasingly competitive environment. This study aims to analyze the differences in BPR financial performance before and after the introduction of fintech services, with a focus on capital adequacy, profitability, and liquidity for the period 2019–2023. The sample consists of 21 BPRs in Bali Province, selected using non-probability sampling with purposive sampling techniques based on specific criteria. Data were collected through non-participant observation. The data analysis techniques employed include normality testing and the Wilcoxon signed-rank test. The results reveal that both Capital Adequacy Ratio (CAR) and Return on Assets (ROA) of BPRs increased after the implementation of fintech services, whereas the Loan to Deposit Ratio (LDR) decreased. The theoretical implication of this study supports Schumpeter’s theory of innovation, which asserts that technological innovations such as fintech services drive qualitative changes in the economic system through the creation of new products, enhancement of service quality, development of operational methods, and the opening of new markets, thereby improving BPR financial performance. The practical implication of this study is to provide insights for BPRs in formulating strategies to improve financial performance, and for potential customers, BPR health indicators may serve as a reference in assessing the reputation of BPRs and building customer trust, which in turn influences their financial performance.
 

Type 2 Diabetes Mellitus (DM) is a disease caused by impaired insulin function, impaired insulin secretion, or both, resulting in a hyperglycemic condition. Patients with type 2 DM generally exhibit characteristics such as a Random Blood Glucose level exceeding 200 mg/dL and an HbA1c  level exceeding 6.5%. The accuracy of medication administration to patients must also consider the rationality of antidiabetic therapy in order to influence the success rate of optimal therapy. This study aims to evaluate the rationality of patient appropriateness and indication appropriateness in outpatients with type 2 DM at Tabanan Regional Public Hospital (RSUD Tabanan). This study employed a semi-quantitative observational research design with a retrospective approach by reviewing patient medical records from the initiation of therapy. Sampling was conducted using purposive sampling, whereby samples had to meet predetermined inclusion criteria. The results indicated that the age group with the highest prevalence of DM patients at RSUD Tabanan was over 56 years old (74%), with a predominance of females (63%). The most common comorbidity among DM patients was hypertension alone (24.5%). Based on the findings, the percentage of patient appropriateness rationality among DM outpatients at RSUD Tabanan was 97.5%, while the percentage of indication appropriateness rationality in type 2 DM outpatients at RSUD Tabanan was 98.5%.

The rapid development of information technology demands that the younger generation, including junior high school students, have a good understanding of how to use digital media safely and responsibly. This seminar aims to provide education on the effective use of email and raise students' awareness about the importance of cybersecurity. The activity was held at SMPN 1 Nonggunong, involving seventh-grade students. The topics covered included the basics of using email, digital communication etiquette, and potential cybersecurity threats such as phishing, malware, and personal data breaches. The implementation methods included material presentations, interactive discussions, and case simulations. The evaluation results showed an 85% improvement in students' understanding of digital security practices, based on pre-test and post-test assessments. This aligns with the findings of Andria et al. (2024), which state that cybersecurity training effectively enhances students' digital literacy. This seminar also supports the research of Giap et al. (2024), which emphasizes the importance of interactive education in increasing digital awareness among teenagers. It is hoped that similar activities can be conducted on a sustainable basis as part of the school's digital literacy curriculum, given the importance of instilling online security practices from an early age.