Air pollution is one of the most pressing environmental issues with significant impacts on human health. This study aims to examine the relationship between air pollution levels and human health disorders, as well as to identify effective mitigation solutions. Using a descriptive qualitative approach, data were collected through literature reviews from various journals, WHO reports, and other official sources. The analysis shows that exposure to air pollutants, particularly fine particulate matter (PM2.5), carbon monoxide, nitrogen dioxide, and ozone, can trigger respiratory, cardiovascular, and mental health disorders, and adversely affect children and pregnancies. These impacts are both short-term and long-term, including increased premature mortality and reduced quality of life. To minimize these effects, strategic solutions are needed, such as strengthening emission regulations, promoting eco-friendly transportation, using air purifiers, developing green open spaces, and providing public education. This study emphasizes the importance of collaboration between the government, society, and the private sector in creating clean air and a sustainably healthy environment.

Diabetes is the body’s inability to efficiently break down sugar or secrete enough insulin required to process glucose, which supports normal bodily functions. Diabetes, as a prevalent chronic disorder, has contributed to numerous underlying health challenges among its carriers and is classified by the WHO as the world’s deadliest disease and silent killer. Its non-communicable nature makes early diagnosis difficult, allowing progression through various stages: type I, type II, pre-diabetes, and gestational. This challenge is further compounded by the imbalanced nature of diabetes datasets, which leads to high misclassification, poor generalization, and reduced accuracy. This study predicts diabetes using a bi-directional long short-term memory (BiLSTM) model applied to two datasets: (a) PIMA Indian Diabetes and (b) Iraqi Society Dataset, to evaluate the impact of six known balancing techniques and assess their effectiveness. Results show that for PID, the SMOTE-Tomek fused BiLSTM outperforms other balancing schemes with F1, Accuracy, Precision, Recall, and Specificity scores of 0.9182, 0.9198, 0.9128, 0.9248, and 0.9208, respectively. For ISD, it also achieves the best performance with values of 0.9367, 0.9369, 0.9386, 0.9388, and 0.9313, respectively. Other balancing approaches yielded F1 scores ranging from [0.6751 to 0.9347], accuracy [0.684 to 0.9358], Precision [0.6851 to 0.9296], Recall [0.6639 to 0.9356], and specificity [0.6658 to 0.9298]. These results imply that BiLSTM is resilient to the vanishing gradient problem and can effectively classify diabetes cases with enhanced performance.

Merokok merupakan salah satu kegiatan yang menyebabkan masalah kesehatan yang serius bagi masyarakat, karena dapat menyebabkan berbagai penyakit kronis dan ketergantungan. Selain itu, interaksi antara perokok dan non-perokok juga berisiko, karena paparan asap rokok dapat meningkatkan kemungkinan terjadinya penyakit pada individu yang tidak merokok. Untuk mengatasi permasalahan ini, maka perlu adanya pengontrol optimal yang efektif mampu menekan banyaknya perokok konvensional dan perokok elektrik. Metode lagrange digunakan untuk menyelesaikan permasalahan kontrol optimal. Edukasi terkait bahaya merokok diberikan kepada individu yang berpotensi merokok, agar mereka tidak menjadi perokok konvensional atau perokok elektrik. Kampanye difokuskan untuk meningkatkan kesadaran tentang manfaat berhenti merokok, dan ditujukan untuk perokok baik konvensional maupun elektrik. Hasil simulasi menunjukkan bahwa dengan melakukan kontrol melalui edukasi tentang bahaya merokok pasif dan kampanye berhenti merokok efektif dalam menurunkan jumlah perokok. Hal ini menunjukkan bahwa metode lagrange dapat menjadi pendekatan yang efektif dalam mengendalikan populasi perokok.

This study was conducted with the aim of determining the effect of profitability represented by Return On Assets (ROA), Return On Equity (ROE), Earning Per Share (EPS) and Capital Structure represented by Debt to Equity Ratio (DER) on Stock Returns in Infrastructure sector companies listed on the Indonesia Stock Exchange (IDX) for the period 2021-2023. The number of samples in this study were 43 companies with a total of 109 data.  This study uses an associative method with a quantitative approach. The data source used is secondary data. The data analysis method used are descriptive statistical analysis, classical assumption test, multiple linear regression analysis, hypothesis testing, and determination coefficient test (R2). The results of this study are that ROA has a positive and significant effect on stock returns. ROE has a positive and significant effect on stock returns. EPS has no effect on stock returns. DER has a negative and significant effect on stock returns

This study was conducted to determine: 1) the influence of work-life balance on employee performance at PDAM Tirta Limutu, Gorontalo Regency, 2) the influence of co-worker support on employee performance at PDAM Tirta Limutu, Gorontalo Regency, and 3) the influence of work-life balance and co-worker support on employee performance at PDAM Tirta Limutu, Gorontalo Regency. This study is associative with a quantitative approach, which aims to analyze the relationship between the variables studied. The data analysis method used is multiple linear regressions. The primary data analyzed was obtained through interviews and direct observation of the research object. The data collection process was carried out by distributing questionnaires to respondents. At the same time, the sampling technique used the census method, where the entire population was used as a sample in this study. The results of the study indicate that partial work-life balance (X1) has a positive and significant effect on the performance of PDAM Tirta Limutu employees in Gorontalo Regency, support from co-workers (X2) has a positive and significant effect on the performance of PDAM Tirta Limutu employees in Gorontalo Regency. Simultaneously, work-life balance and support from co-workers positively and significantly affect the performance of PDAM Tirta Limutu employees in Gorontalo Regency.

This study aims to analyze the effect of data security, ease of use, and access speed on user trust in mobile banking applications in Indonesia. In the growing digital era, user trust is a crucial factor in determining the success of mobile banking applications. This research adopts a case study approach by selecting two widely used mobile banking apps in Indonesia: Bank Mandiri and Bank BNI. Data were collected through in-depth interviews with 20 active users of the apps, as well as observation of the apps' interface and features. The study used thematic analysis to identify key themes that influence users' perceptions and trust in the apps. The results show that data security is the most influential factor on user trust, followed by the ease of use of the app, which also plays an important role in increasing user trust. Meanwhile, although access speed does have an impact, it is less significant compared to the other two factors. The findings provide important insights for mobile banking app developers to improve these aspects, strengthen user trust and loyalty, and promote the adoption of digital banking technology in Indonesia.

Science literacy is an important 21st century competency, but Indonesian students' ability in this aspect is still low. Based on PISA results, Indonesia is ranked 68th, with only 34.16% of students reaching level 2, far below the OECD average of 75.51%. One of the factors causing this is the lack of variety of learning media used by teachers. This study aims to describe the development process, validity, effectiveness, and practicality of the Adventure of Si RAMA with Augmented Reality media in improving the science literacy of elementary school students. The research used the Research and Development (R&D) method with the ADDIE model. The stages in this development research include identification of potential and problems, analysis, product design, design development and product validation, product revision, product trials, and evaluation. The validation results showed very high scores from material experts (90%), learning design (94%), and media (95 The effectiveness of the media is seen from the T Test results which resulted in a sig. value of 0.000, which is smaller than 0.05, which indicates that this media is effective in improving science literacy. Practicality assessment from students reached 89% and from teachers 92%, both of which were in the very practical category. Thus, this media is worth using as an innovative learning alternative to support the improvement of science literacy in elementary schools.
 

Employee performance in service companies in Indonesia is often hampered by less than optimal organisational culture and work motivation, which impacts on the productivity and competitiveness of the company. This study aims to explore the influence of organisational culture and work motivation on employee performance in service companies in Jakarta. The method used is a quantitative survey with a Structural Equation Modeling (SEM) approach using AMOS, involving 120 respondents selected by purposive sampling. The results of the analysis show that organisational culture and work motivation simultaneously have a positive and significant effect on employee performance, with work motivation having a more dominant influence. This finding strengthens human resource management theory regarding the importance of integrating organisational culture and motivation in improving performance. The practical implication of this study is the need to develop a holistic management strategy to strengthen organisational culture and increase work motivation to encourage optimal employee performance in the service sector. This research also opens up opportunities for further studies with a mixed methods approach and mediating variables to enrich the understanding of human resource dynamics in Indonesia.

This study aims to review the latest developments in medicinal chemistry and its prospects in the development of future treatments. Through a comprehensive literature study approach, this study analyzes the latest innovations in drug design and development, including the use of computational technology, nanotechnology, and biological target-based approaches. The results show that the integration of artificial intelligence and machine learning technologies with conventional medicinal chemistry techniques has opened a new paradigm in more efficient and precise drug discovery. Personalization of treatment based on patient genetic profiles, development of new antibiotics to overcome antimicrobial resistance, and nanomaterial-based therapies are important trends in contemporary medicinal chemistry applications. This study concludes that the future of medicine will be greatly influenced by advances in medicinal chemistry, with the main challenges being safety, regulation, and accessibility.More intensive multidisciplinary collaboration is needed between chemists, biologists, pharmacologists, clinical medicine, and informatics to optimize the potential of medicinal chemistry in the future medicine revolution.

This research aims to analyze the causes of the KM ship accident. Kirana I and the role of the Tanjung Emas Class I Harbormaster and Port Authority Office (KSOP) in improving shipping safety. Using a qualitative approach, data was collected through observation, interviews and documentation. The research results show that accidents are caused by human negligence, especially from ship crews who ignore safety procedures, even though the ship has met all safety certification requirements. Weather factors also contributed to the incident. KSOP Class I Tanjung Emas plays an important role in monitoring shipping safety through routine inspections and issuing Sailing Approval Letters (SPB). This research recommends increasing regular shipping safety training and outreach to ship crews and port officers, as well as strengthening coordination between agencies to create a better safety culture in the shipping environment.