The disease caused by the Corona Virus has afflicted hundreds of millions of individuals. The virus that causes the disease is SARS-CoV-2. To treat a variety of ailments, the Indonesian population favours the usage of medicinal herbs. The 1,8- cineol, karyophyllene, limonene, α-terpineol, α-pinene, dan β-pinene chemicals are present in eucalyptus oil (Melaleuca cajuputi) used in traditional medicine. This research was undertaken in silico to investigate the efficacy of these drugs as SARS-CoV-2 Main Protease (Mpro) inhibitors. The 1,8- cineol, karyophyllene, limonene, α-terpineol, α-pinene, dan β-pinene chemicals were molecularly docked using AutoDock Vina. Berdasarkan hasil molecular docking diperoleh Gibbs free energy (ΔG) dari kariofilen (-5.6 Kkal/mol), 1,8-cineole (-5.2 Kkal/mol), α-terpineol (-5.0 Kkal/mol), α-pinen (-4.9 Kkal/mol), β-pinen (-4.9 Kkal/mol), dan limonen (-4.8 Kkal/mol). Based on the results, the molecular docking data on these compounds likewise demonstrated no RMSD value greater than 2 Å. It indicates that the connection between the receptor and ligand is stable and that the response can occur spontaneously. The active site of the Mpro enzyme is the amino acid residue, where the interaction between the receptor and ligand occurs. Based on the bioactivity test, it can be inferred that the 1,8- cineol, karyophyllene, limonene, α-terpineol, α-pinene, dan β-pinene chemicals have varying bioactivities on different pharmacological targets. Because they satisfy Lipinski's requirements, these chemicals can also be utilized as oral medications. In addition, the toxicity test demonstrated that the test ligands exhibited minimal toxicity.

The programs and strategies that must be carried out by the broadcast media in dealing with this are the coordination of the national revival movement which is directed primarily at strengthening the resilience of the community and the nation against all efforts to destroy the character and cultural values of the nation. , the state, not only very broad, but also fast and efficient. simultaneously. Broadcast media in carrying out their duties as service media, disseminator of information, inheritance of cultural values, educating, entertaining, social control, advertising media, must be able to convey messages so that the public can obtain clear, complete, honest, ethical and moral and objective information. The conclusion of this discussion is that the function of media coverage and broadcasting needs to be studied to make it easier if you want to do a media program, and some of the functions of the media themselves in providing knowledge to the audience in accordance with ethics. . value for broadcasting and reporting activities.
 

Kasus korupsi di Indonesia kian hari semakin meningkat, dikutip pada Suarajakarta.id menyatakan bahwa  korupsi di Indonesia semakin memburuk hingga mencapai 58%  Hal tersebut menjadikan lambat tahun korupsi sebagai budaya di Indonesia dan akan sulit untuk diberantas. Dalam artikel ini akan membahas pengimplementasian pendidikan anti korupsi melalui program pusat edukasi antikorupsi di Sekolah Dasar. Dalam program pusat edukasi antikorupsi yang disediakan oleh pemerintah ini kepada sekolah dinilai cukup efektif dalam membantu pendidik melaksanakan pendidikan anti korupsi. Dengan adanya pendidikan anti korupsi melalui program ini diharapkan dapat menciptakan manusia yang memiliki akhlak yang baik, pengetahuan yang luas, kesadaran pada diri sendiri akan buruknya melakukan tindakan korupsi.
 

The provision of health services is one way to meet the needs and demands of the community for health, in the process including health financing. There are six financing patterns applied, one of which is out of pocket financing and Social Health Insurance Administration Body. The ability to buy health services depends on the readiness of the family to finance the household, so socioeconomic status influences the use of health financing patterns. This study uses quantitative methods with a cross-sectional research design. The population is the head of the family who seeks treatment at Abdul Manap Hospital, with as many as 89 respondents. Data collection using a questionnaire and data analysis using chi-square. Based on the analysis, the variables that have a relationship with the pattern of Social Health Insurance Administration Body financing are income (p-value 0.000), occupation (p-value 0.003), number of family members (0.028), and asset ownership (0.000). Meanwhile, the one that does not have a relationship is education (0.276). The conclusion of this study is that income, occupation, the number of family members, and asset ownership have a relationship with the use of financing patterns, while education has no effect.

The research in this dissertation is motivated by the phenomenon of the development of quality educational institutions that have a good process to create high student achievement, design a good curriculum taught by qualified teachers and good products as evidenced by the students being able to compete with superior schools. inside and outside the city so that, with a good process, Madrasa are no longer underestimated and even become the community's main choice of superior schools. The research approach uses qualitative methods. Data collection techniques are participant observation, in-depth interviews and documentation. The data analysis techniques used are 1) single case data analysis, 2) cross-site analysis. From the results of this study, it can be concluded that: ( 1) The formulation of the madrasa principal's strategy in developing students' talents and interests at MTsN 3 Nganjuk and MTsN 2 Kediri City is carried out by : formulating the vision and mission of the madrasa, determining the goals of planning for the development of student talents and interests that have been carried out by the madrasa, mapping talents and interests based on abilities and fields of study . Recruitment of basic education students with implementation of strict selection assessment taking into account several assessments, namely the recruitment of the academic path through with report cards and Olympics. Non-academic selection recruitment is seen from the results of students' memorization of the Koran, sports, arts and so on . (2) The implementation of the madrasa principal's strategy in developing students' talents and interests at MTsN 3 Nganjuk and MTsN 2 Kediri City is carried out by: 1) Programs of extracurricular activities provided for all students according to their potential, interests, talents, and abilities, so that students can develop maximally. 2) Supporting activities through routine and spontaneous activities that are carried out optimally can develop students' talents and interests.

Tooth discoloration is one of the most common concerns associated with dental appearance or cosmetic issues. Teeth whitening is one of the conservative procedures that may be utilized to overcome tooth discoloration (bleaching). Utilizing natural bleaching agents is a safer, less expensive, and more accessible option. Malic acid (malic acid) and elegat acid (allegic acid) obtained from fruits can be used to whiten teeth. White pomegranate (Punica granatum L.) is one of these all-natural components. The purpose of this research was to evaluate the efficacy of white pomegranate extract gel as a bleaching agent against tooth discoloration. This research utilizes an experimental laboratory design. There were 24 mandibular second premolars utilized as samples. All teeth were submerged for seven days in the coffee solution. Utilizing spectrophotometry, tooth discoloration was measured. After being soaked in a coffee solution and then a white pomegranate extract gel, the item was dried. Group 1: teeth soaked in white pomegranate extract gel with a concentration of 70%. Group 2: teeth soaked in white pomegranate extract gel with a concentration of 80%. Group 3: teeth soaked in white pomegranate extract gel with a concentration of 90%. Group 4: 10% carbamide peroxide gel as a positive control.  Each specimen was immersed for 56 hours. Using a spectrophotometer, tooth discoloration was assessed following immersion in white pomegranate gel extract and carbamide peroxide gel. Based on the results of the LSD test, the % group was determined to be the most effective as a teeth whitening agent. White pomegranate extract gel has an influence on tooth discoloration and tooth whitening attempts.

The existence of waste at this time was still a problem that hit almost all regions in Indonesia. Keliling Danau Districts in 2019 has produces 33,311 m3 of waste per year with a population of 22,207 people. The purpose of this study was to determine the determinants behavior of waste management in elementary school students at Kerinci Regency, 2021. This study aims to determine the relationship between knowledge, attitudes, and Availability of Facilities with Waste Management in State Elementary School 52 of Koto Dian students, Kerinci Regency. This research is quantitative with a cross sectional research design. Sampling using random sampling technique with a total sample of 44 students consisted of class III, IV, V to class VI. Data was collected by distributed of questionnaires. Analysis used chi-square test. The results of this study indicate that 18 of 44 (40.9%) respondents with poor behavior of waste management and 26 (59.1%) respondents with good behavior waste management. From the results of the bivariate test, it was found that Knowledge has a PR value = 3.33 CI = 1.73-6.39 and a p-value of 0.001 indicates that there is a relationship between knowledge and behavior of waste management. Attitude has a value of PR = 3.75 CI = 1.62-8.68 and a p-value of 0.001 indicates that there was a relationship between attitude and behavior of waste management and there was not relationship between availability of facilities and behavior of waste management with a p-value of 0.222. The conclusion of this study is that there is a relationship between knowledge and attitudes with behavior waste management. And the availability of facilities has no relationship between behavior of waste management in elementary school students.

This study aimed to analyze the production of chitosan-encapsulated vicenin-2 extracted from basil leaves and its effect on non-small cell carcinoma lung cancer. Vicenin-2 Extract from Chitosan-Encapsulated basil (Ocimum sanctum Linn.) leaf extract is produced by library research and laboratory practice. In non-small cell carcinoma lung cancer, vicenin-2, one of the components in basil leaves, and chitosan capsules, which are deacetylated chitin, had a substantial anticancer effect. It is required to investigate the effectiveness and safety of basil leaf powder containing mostly vicenin-2 and encapsulated in chitosan capsules.

Bencana banjir menerjang Kota Bima, Nusa Tenggara Barat. Badan Penanggulangan Bencana Daerah (BPBD) Kota Bima telah melakukan upaya penanganan darurat merespons bencana tersebut. Seperti dikutip dari siaran pers BNPB, BPBD Kota Bima telah mengevakuasi warga yang terdampak banjir di 4 kecamatan, yaitu Kecamatan Asakota, Rasanae Barat, Raba dan Mpunda. BPBD dibantu personel TNI dan Polri dalam mengevakuasi warga. Langan bencana, metode penelitian yaitu observasi, wawancara, dan dokumentasi. Adapun strategi komunikasi yang dilakukan oleh pemerintah kelurahan dalam menanggulangi bencana, baik itu yang bersifat mengantisipasi bencana maupun setelah terjadinya bencana atau pasca bencana terjadi sangat beragam dan menggunakan metode yang berbeda-beda. Pemerintah Kelurahan dalam hal ini, telah melakukan berbagai upaya strategis dalam menangulangi bencana banjir tersebut terutama dalam hal melakukan koordinasi dengan berbagai pihak terkait, agar pihak-pihak terkait dapat membantu dan menentukan langkah strategis guna mempercepat pemulihan masyarakat yang terkena dampak banjir baik pemulihan secara fisik maupun non fisik. Terkait langkah strategi komunikasi yang dibangun oleh Pemerintah Kelurahan dalam melakukan komunikasi baik secara vertikal maupun horizontal kepada semua unsur yang ada pada Pemerintahan Daerah maupun Pemerintah Propinsi, dalam hal ini seluruh komponen masyarakat juga dilibatkan dalam upaya pemulihan dan pencaian perbaikan aspek sarana dan parasana pasca banjir..
 
 

PT SURYABUMI AGROLANGGENG is a company engaged in the plantation and palm oil processing industry. The problem that occurs in the company is the occurrence of defects in CPO oil in the form of defects in the raw material, namely FFB (Fresh Fruit Bunches), where the defects consist of F00, F0, and F5 defects with large defects, namely 28.16% FFB with fraction 0, then there are 12.07% FFB with a fraction of 00, and there are as many as 18.63% FFB with a fraction 5. From the problems and conditions that occur in the company, quality control can be carried out. One of the quality control techniques is using the six sigma method.
Six sigma method is a statistical concept that measures a process related to defects at the level of six (Six) sigma. Six sigma focuses on eliminating defects by emphasizing understanding, measuring, and improving processes. In six sigma there are 5 phase cycles namely Define, Measure, Analyze, Improve, and Control
Based on the results of data processing, it is known that the most dominant type of defect is Fraction 0 of 47.4%, from analysis using a fishbone diagram there are 4 factors causing defects, namely human, material, machine, and environmental factors. The improvement solutions obtained are conducting training, increasing work motivation with rewards, designing sorting aids using automatic technology, tightening and increasing supervision during harvesting, paying attention to lighting needs, implementing 5 S, monitoring production room temperature regularly, conducting trials. the machine before being used for the production process, replace the old pipe or sludge tank with a new one.