Micro, Small, and Medium Enterprises (MSMEs) are one of the sectors that have an important role in supporting Indonesia's national economy. Its contribution is enormous to the Gross Domestic Product (GDP), job creation, and increased innovation, especially in the face of global economic challenges and social inequality. This research aims to examine in depth the role of MSMEs in encouraging Indonesia's economic growth and identify various challenges faced by this sector. The method used in this study is library research, by analyzing various sources of scientific literature, policy reports, and relevant empirical data related to the role of MSMEs. The results of the study show that MSMEs not only contribute to increasing national GDP, but also become the main driving force in providing jobs for the community, especially in rural and suburban areas. In addition, MSMEs are also an important means in the development of local innovation, especially in the use of simple technology that is in accordance with community conditions. However, MSMEs also face a number of serious challenges that can hinder their contribution to economic growth. These challenges include limited access to digital payment systems, low quality of human resources (HR), weak marketing networks, and limited capital and technology. Thus, to increase the role of MSMEs in national economic development, synergy is needed between the government, the private sector, and financial institutions in providing comprehensive and sustainable support. The support includes training on human resource capacity building, access to capital, digital transformation, and strengthening the business ecosystem. This research is expected to contribute to the development of policies that favor the empowerment of MSMEs in Indonesia.

This research was motivated by the problem of children's low ability to coordinate hand and vision movements, which directly impacts their activities and fine motor skills. This study aims to describe the activities of teachers and children and analyze the development of fine motor skills in group A students at Hidayatullah Kindergarten Barito Kuala. This study used a Classroom Action Research (CAR) approach with a qualitative design and was conducted over four meetings. The results showed a significant increase in teacher activities and the development of children's fine motor skills. Teacher activities that initially received a score of 18 in the fairly good category increased to a score of 32 in the very good category at the fourth meeting. Meanwhile, at the beginning of the intervention, only 7% of children were in the Very Well Developed (BSB) category. After the first intervention, the percentage of children in the BSB category increased to 27% or five children. A more significant increase occurred at the fourth meeting, with 14 children or 82% falling into the BSB category. The intervention used a project-based learning model combined with a demonstration method in stringing activities using natural materials. Based on the results obtained, it can be concluded that this model is effective in improving fine motor skills in early childhood. This combination of approaches encourages active child engagement and provides meaningful and contextual learning experiences, contributing to optimal fine motor development.
 

This study aims to examine the extent to which social media is utilized in agribusiness learning among students at Universitas Adzkia. A quantitative descriptive approach was employed, using a Likert scale-based questionnaire as the research instrument. The collected data were tabulated and classified into score percentages to determine the category of social media utilization. The research was conducted from June to July 2024 using a census method, involving all 38 students enrolled in the Agribusiness Study Program at Universitas Adzkia. The findings indicate that overall, the use of social media in agribusiness learning falls into the moderate category, with a score percentage of 55.76%. When broken down into agribusiness sub-systems, the results show that the use of social media in the agricultural input supply sub-system was 55.76%, in farming activities 56.14%, agricultural product processing 49.67%, marketing 44.08%, and agribusiness support services 47.20%. These results suggest that although social media has been used in the learning process, its utilization is still at a moderate level and not yet evenly distributed across all agribusiness sub-systems. This presents both opportunities and challenges for lecturers and educational institutions to develop more innovative, technology-based learning strategies. To enhance the effectiveness of agribusiness learning, it is recommended that lecturers actively encourage students to use social media in a productive manner. This could be implemented through the assignment of structured tasks that require the use of social media platforms for academic discussions, information searches, and the creation or sharing of relevant agribusiness content. Such efforts are expected to make social media not only a tool that enriches students' learning experiences but also a means to deepen their understanding of the dynamic and ever-evolving field of agribusiness. Ultimately, integrating social media into learning can support the development of digital competencies and practical insights among agribusiness students in higher education.

The transition to Industry 5.0 necessitates a robust legal framework to regulate human capital investment, ensuring digital workforce development aligns with labor protections and Sustainable Development Goals (SDGs). This study examines the regulatory structures governing human capital investment in Indonesia, the European Union, and the United States, evaluating their effectiveness in addressing digital transformation challenges, AI-driven employment governance, and workforce adaptability. A mixed-methods approach integrates legal analysis with empirical assessments of policy effectiveness, workforce investment trends, and labor market outcomes. Findings reveal significant disparities in AI workforce governance, skill accreditation, and automation labor rights. Indonesia’s fragmented legal framework hinders workforce reskilling and AI employment governance, while the European Union’s AI Act provides a structured, albeit inconsistently implemented, model for digital employment regulation. The United States, despite its technological leadership, lacks federal AI workforce policies, leading to state-level regulatory variations. The study underscores the necessity of harmonized legal frameworks to bridge workforce skill gaps, protect labor rights, and advance SDG-aligned workforce policies. Future legal reforms must prioritize AI governance, digital workforce training, and cross-border labor protections to ensure equitable workforce transitions. Strengthening public-private partnerships, standardizing AI employment regulations, and enhancing labor rights enforcement will be essential for fostering sustainable human capital investment in the industry 5.0 era. The contribution of research extends beyond theoretical frameworks, providing substantial implications for policy formulation, industry practices, educational advancements, and societal improvements.

Metabolic syndrome (MetS) is influenced by parental traits and diet. Drosophila melanogaster is a potential disease model organism, sharing physiology and genetic similarities with humans. Previous research had focused on Drosophila melanogaster as a model organism for obesity and diabetes, but not for MetS. This research aimed to determine the effect of both parental diet and high sugar fat (HSF) intake on glucose, cholesterol, and triglyceride hemolymph levels of Drosophila melanogaster. Wild flies were purified in either control (standard) or MetS media (extra 3% sucrose and palm oil). Seventy-five pairs were divided into 5 groups, according to parental origin and feeding media, and maintained in five generations (F1-F5). Glucose, triglyceride, and cholesterol levels were measured using a colorimetric assay in three replications of each generation per group. Glucose, triglyceride, and cholesterol levels were significantly different in all treatment groups, the control groups, and between generations in each group (p<0.05). Higher glucose and triglyceride levels appeared in the youngest generation (F5) of all groups, and in the flies reared on HSF diets. Maternal HSF-exposed groups demonstrated a more pronounced impact of parental metabolic state on the glucose and triglyceride levels of the earlier generation. These findings highlight that parental exposure to HSF and prolonged HSF intake independently and synergistically lead to persistent and amplified metabolic dysregulation across generations. Drosophila melanogaster, modeled in this study, represents a novel experimental organism that is suitable for studying the epigenetic inheritance of MetS, gaining more consideration for the metabolic health consequences of long-term dietary habits and parental metabolic state.

The presence of natural antioxidants in medicinal plants plays a crucial role in inhibiting the detrimental effects of oxidative stress. The aim of this research is to explore more deeply all parts of A. esculenta L from flowers, fruits, seeds, leaves, and stems for the levels of compounds and antioxidant and enzyme inhibitor activities. The flowers demonstrated the highest TPC with 173.15942 ± 6.5083 mg GAE/g. The stems exhibited the lowest TPC value at 69.1967 ± 2.8408 mg GAE/g. The flowers also showed TFC value of 83.157 ± 2.021 mg QE/g while the stems displayed the lowest with 36.7240 ± 1.337 mg QE/g. IC50 value that the flowers possessed the highest antioxidant activity with 22.6539 ± 1.6452 mg/mL, whereas the stems displayed a slightly lower. In terms of the inhibitor of a-amylase activity, the flowers had an IC50 value of 102.4885 ± 11.4370 mg/mL whereas the stems had a lower. The highest IC50 value of the a-glucosidase inhibitor was 76.95 ± 12.0888 mg/mL in the flowers, and the lowest was in the stems. The highest IC50 of pancreatic lipase inhibitor was 109.5943 ± 9.7391 mg/mL in the flowers, and the lowest was in the stems. This study show that there is a relationship between the high content of total phenolic and total flavonoids on antioxidants, antidiabetic and antilipase activities.

Indonesia, a leading palm oil producer, generates 1,250 tons of Oil Palm Empty Fruit Bunches (OPEFB) waste daily, typically disposed of through polluting combustion. This study explores repurposing OPEFB as a substrate for erythritol production, a popular sweetener with minimal impact on blood sugar. The research utilized Moniliella pollinis mutant SP5, a yeast capable of producing erythritol from various substrates. The process involved acid hydrolysis of OPEFB followed by fermentation. When fortified with 15% v/v molasses, OPEFB successfully served as an optimal carbon source for erythritol production, achieving a mass yield of 0.2878 g/g. Further improvement came through the use of ethyl methane sulfonate (EMS) mutagenesis, with the best mutant (mutant 7) reaching a yield mass of 0.3298 g/g and volumetric productivity of 0.0534 g/L/h. This research aims to advance Indonesia's self-sufficiency in erythritol production while providing a sustainable solution for OPEFB waste reduction, simultaneously addressing economic and environmental concerns.

The use of synthetic feed additives in Peking ducks has adverse effects on their growth and productivity. Spirulina sp., a blue-green algae, has the potential to be used as a safe feed additive that can enhance the growth and productivity of ducks. This study aims to analyze the effects of Spirulina (Spirulina sp.) powder as a feed additive on the histomorphometry of the duodenum in Peking ducks (Anas platyrhynchos), focusing on the duodenal lumen diameter, villus height, villus width, mucosal tunic thickness, submucosal tunic thickness, and muscular tunic thickness. This study used a Completely Randomized Design (CRD) with 35 ducks divided into 5 treatments and 5 repetitions. The treatments included a control group and the addition of spirulina powder in feed at concentrations of 2.5%, 5%, 7.5%, and 10%. The data were analyzed by ANOVA with a significance level of 5%, followed by Duncan's test. The results of data analysis showed that spirulina powder had a significant effect (P<0.05) on villus height and duodenal mucosa tunica thickness. The conclusion of this study is that spirulina powder has the potential to be used as a feed additive to improve digestive performance in male Peking ducks, as evidenced by the increase in villus height and thick tunica mucosa in the small intestine. The novelty of this study lies in the utilization of spirulina powder as a feed additive to increase the size of the duodenal tissue structure in Peking ducks. The results of this study are expected to be a new reference on the potential of spirulina as a feed additive to improve poultry feed quality and digestive performance, especially in peking ducks.

The study was conducted to evaluate the effects of microbial inoculants and nutrient levels on the agronomic performance of dry direct-seeded NSIC Rc192 rice under aerobic conditions. Six biofertilizer treatments (control, Bio-N, BioGroe, Mykovam, MykoPlus, and Avatar) were combined with four nutrient levels (0 %, 25 %, 50 %, and 75 % NP + full K). The study aimed to assess the impact of these treatments on root colonization, tiller production, and overall plant growth. Root and soil colonization at 60 days after sowing (DAS) revealed that MykoPlus facilitated more effective root colonization than other inoculants. However, unfavorable environmental conditions, including high temperatures and moisture deficits, negatively impacted tiller production and grain yield. Despite these challenges, BioGroe showed the most promise, significantly enhancing root development and tiller count, particularly when combined with 50 % NP + full K. The study concluded that microbial inoculants, especially BioGroe, can improve rice growth under aerobic conditions, but environmental factors are crucial in determining their effectiveness. Further research is needed to optimize these inoculants for varying environmental conditions to maximize their benefits in rice cultivation.

Coral reefs are vital habitats for numerous fish species, providing food, shelter, and breeding grounds. In Jepara Regency, Central Java, Indonesia, these ecosystems are threatened by human activities and natural disturbances. This study aimed to assess the biodiversity of reef fish in relation to coral health degradation. Researchers used the Line Intercept Transect (LIT) and Underwater Visual Census (UVC) methods to evaluate fish abundance and coral coverage across three locations with six sampling stations. 936 reef fish individuals, representing 35 species and 14 families, were recorded, with the Pomacentridae family being the most prevalent. The highest coral coverage, categorized as fair, was found at Location II (Blebak Beach) at Stations 3 and 4, with coverage of 27.93% and 25.61%, respectively. This coral coverage was positively correlated with reef fish abundance, with counts of 238 and 246 individuals (average ± SD: 242 ± 5.65). The biodiversity index indicated a dominance index (D) ranging from 0.05 to 0.14 (in the fair category), a high evenness index (E) between 0.75 and 1, and a low dominance index (D) between 0.05 and 0.14. A significant correlation was found between coral coverage and reef fish numbers (P < 0.05, R² = 0.8702), with a linear regression equation of y=6.26+67.71. The findings suggest that the health of coral reef ecosystems significantly affects reef fish populations. Hereafter, the healthiness of this ecosystem will support the scientific core development of Marine Sciences as well as fulfill society's need (economically).