Pharmaceutical services are carried out to achieve definite results in improving the quality of life of patients in the form of direct and resposibels services related to pharmaceutical preparations. In implementing pharmaceutical services, health centers already have a standard that is used as a guideline in its implementation. The consequences of implementing pharmaceutical services that do not comply with standards are medication errors and inappropriate use of drugs, there are expired drugs and overlapping budgets. The purpose of this study was to analyze the implementation of pharmaceutical service standards in health centers, BMHP and clinical pharmacy services based on PMK No. 74 of 2016 at the Paduraksa Health Center, Pemalang District.
This study is a non-experimental study with a descriptive design that will provide an analytical description of the implementation of pharmaceutical service standards at the Paduraksa Health Center, Pemalang District based on the guidelines in the Minister of Health Regulation Number 74 of 2016. The population and sample in this study were all pharmaceutical personnel who were responsible for managing pharmaceutical service standards at the Paduraksa Health Center, by conducting interviews in the form of questions and answers by giving questions verbally to pharmacists or pharmaceutical personnel at the Paduraksa Health Center, Pemalang Regency. The data in the variable analysis looked at the percentage of compliance with standards based on the Minister of Health Regulation No. 74 of 2016.
 

Soft food served in hospitals is a simple indicator that can be used to evaluate the success of hospital nutrition services. The aim of this study was to determine the perception of oral surgery patients regarding soft food waste at Surya Husadha Hospital Denpasar. This research uses a quantitative descriptive survey method. The total population was 30 people, the number of research samples was 20 people... data collection was carried out by measuring perceptions of taste and food waste using a questionnaire for the 20 samples studied. Data was obtained from filling out a questionnaire about perceptions of soft food and a form for the amount of food waste. The data was analyzed using SPSS version 21 statistical analysis. The results of this study showed that there were porridge food waste in 40-49% (45%) of the sample, 50-59% (40%) of the sample, 60-69% (15%) of the sample. Leftover animal side dishes (0%). Vegetable side dishes (10%). Leftover vegetables (10%) And for juice (0%). It can be concluded that the perception of soft food at Surya Husadha Hospital from this research shows that as many as 40-49% (45%) are not satisfied with the rest of the soft food (porridge).
 

Osteoarthritis is a type of arthritis that occurs in the area around the joints because the cartilage that protects the ends of the bones begins to break down accompanied by reactive changes at the edges of the joints which can cause pain and difficulty moving. Drug use is said to be rational if the patient receives treatment that is in accordance with clinical needs, namely correct diagnosis, correct drug selection, correct indication, correct dose, correct method of administration, and correct patient. This research aims to use a descriptive analysis design for observational research. The research design used was quantitative research to determine the rationality of using NSAIDs anti-pain medication in osteoarthritis patients undergoing treatment at the Klinik Teluk Banten. The rationality results in this research are, 100% correct diagnosis, 100% correct indication. 100% correct choice of drug, 89% correct dose, 100% correct method of administration, 94% correct patient for Osteoarthritis at Klinik Teluk Banten.

High exposure to sunlight in tropical areas such as Indonesia increases the risk of skin damage due to ultraviolet (UV) radiation. Sunscreen functions to protect the skin from the bad effects of UV rays, and a good level of knowledge is expected to increase awareness of its use. Surf trainers, who are frequently exposed to sunlight, need proper knowledge and awareness to prevent these negative impacts. This research aims to determine the relationship between the level of knowledge and awareness of the use of sunscreen among surfing trainers at Kuta Beach. The research used an observational design with a cross-sectional approach. The sampling technique used the accidental sampling method with a total of 57 respondents. Data was collected using a questionnaire, and data analysis was carried out using the Spearman correlation test using SPSS version 25. The results showed that 96.49% of respondents had a good level of knowledge, while only 3.5% of respondents had awareness of the use of sunscreen, which was a very low percentage. The results of statistical analysis show that there is no significant relationship between the level of knowledge and awareness of the use of sunscreen with a significance value of 0.469 (p > 0.05).

Cassia alata L or generally knowles as Chinese leaves contain phytochemical compounds, one of which is flavonoids which have the potential as antioxidants, antioxidants can be used to prevent diseases with oxidative stress. The purpose of this study was to determine the content of phytochemical screening and qualitative testing of antioxidant activity ethanol ekstract of Chinese leaves (Cassia alata L) using the DPPH method. This study is a qualitative study with an extraction process using the maceration method with 96% ethanol solvent. Phytochemical screening and antioxidant activity testing were carried out by adding specific reagents. The results of phytochemical screening and antioxidant activity testing of Chinese leaves (cassia alata L) ekstract contain bioactive compounds such as flavonoids, saponins, tannins and antioxidant activity testing with DPPH reagents showed that Chinese leaves (cassia alata L) extract has antioxidant activity which is indicated by a change of the color from purple to yellow. From the results obtained, it can be concluded that the flavonoid compound content in Chinese leaves (cassia alata L) extract can potentially act as an antioxidant.

Origanum majorana demonstrates a broad spectrum of effectiveness against various diseases, exerting antimicrobial effects against different pathogenic microorganisms. The goals of this research are to provide light on how Origanum majorana extract inhibits human pathogenic bacteria, how it may prevent biofilm development, and how it affects bacterial adhesion. The antibacterial activity of the water-based Origanum majorana extract was assessed in this research using two different methodologies. "Antibiotics were compared to its effectiveness using an agar-well diffusion assay and disc diffusion method," the first step. Additionally, the extract's ability to inhibit biofilm formation and bacterial adherence was assessed through specialized tests. All bacterial isolates of Gram negative, Gram-positive bacterial types were sensitive to Origanum majorana extract and the range of inhibition zone (30 to 24) mm. Although floxacin was effective against some of these isolates, the majority of them were resistant. Most bacterial Gram negative types were exhibit moderate adherence and biofilm activity to this extracts and some bacterial isolated of bacteria were exhibit high adherence and biofilm activity to the watery extracts of Origanum majorana. This research confirms previous findings that Origanum majorana extracts are very effective against a wide variety of clinical isolates of bacteria, including Gram-negative as well as Gram-positive varieties. Notably, the extracts were found to be more effective than commercially available antibiotics. Furthermore, the extracts displayed significant inhibition of bacterial adherence and biofilm formation. Based on these findings, Origanum majorana extracts have great promise as an effective antibacterial and anti-biofilm agent.

Fish is one type of aquatic product widely used by the community because of its advantages as a food ingredient, including a source of important nutrients such as protein, vitamins, fat, and minerals. Fish is often found in cans. Canned packaging contains the heavy metals lead (Pb), cadmium (Cd), and zinc (Zn), which can be released into food due to the long storage period. This study aims to identify and analyze heavy metals Pb, Cd, and Zn levels in canned tuna with an expiration date of less than 1 year. Samples of canned tuna came from five different brands. Qualitative analysis used color reagents, while quantitative research used an atomic absorption spectrophotometer (AAS). The qualitative study results showed that three samples of tuna contained heavy metals. Samples B and C were positive for Pb metal, while samples A and B were positive for Zn metal. The concentration of Pb metal was measured in sample B at 117.9 mg/Kg and in sample C at -0.0147 mg/Kg. The concentration of Zn metal in sample A was -0.0048 mg/Kg, and in sample B, it was -0.147 mg/Kg.
 

Providing additional recovery food (PMT), especially for vulnerable groups, is one of the supplementation strategies in overcoming nutritional problems so that cases of malnutrition and malnutrition can be prevented. The aim of this research is to determine the effect of giving supplementary feeding (PMT) biscuits to underweight toddlers on increasing the weight of toddlers at the Rantau Selamat Community Health Center, East Aceh in 2024. This quasi-experimental research uses a one group pre-post test design, namely the existing research design. pretest before being given treatment and posttest after being given treatment. The sample for this research was the entire research population, namely 61 people. Based on the results of this research, the weight status of respondents before the implementation of the PMT program at the Rantau Selamat Community Health Center was underweight for 10 toddlers. The results of the paired T-test statistical test in the second month, the change in toddler's weight before and after PMT-P was shown by the value p=0.000 (p<0.05), so it can be concluded statistically that there is an effect of giving additional food (PMT) on weight status in underweight toddlers (aged 6-33 months). Through this research, it is hoped that it can provide education and increase insight to parents of suffering toddlers to pay more attention to the food intake they consume every day. So that toddlers get adequate nutritional intake in an effort to improve the child's nutritional status.

Traditional medicine is currently developing rapidly, especially those based on plants. Active plant compounds are the main basis for the development of new drugs, which after further research, can be commercialized and used in pharmaceutical treatment. This review was conducted to identify the pharmacological effects of active drug compounds isolated from medicinal plants by conducting a literature study. The results of the literature review contained 37 articles that met the inclusion criteria. Until now, there are several active drug compounds from plants that are sold commercially in the form of modern drugs. Some of the pharmacological effects found are cardiac glycosides, anticholinergics, antiplatelets, analgesics, anticancer, sympathomimetics and antimalarials. This search shows that natural materials are still used as a potential source of active drug compounds, thus encouraging research to find new active compounds from medicinal plants to overcome diseases in the future.

This meta-analysis evaluates the effectiveness of community-based interventions in addressing complex trauma among children in Gaza through a systematic analysis of 42 studies (N=4,873) published between 2010 and 2024. The findings reveal a significant treatment effect (g=0.78, 95% CI [0.65, 0.91], p<.001) with moderate heterogeneity (I²=68%). School-based interventions demonstrate the greatest effect (g=0.89), followed by family interventions (g=0.76) and peer-group interventions (g=0.65). Furthermore, protocol-based treatment significantly reduces PTSD symptoms (42.3%), anxiety (38.7%), and depression (35.2%) among children in Gaza. Moderator analysis identifies intervention duration (?=0.34, p<.01) and family involvement (?=0.29, p<.01) as significant predictors of successful treatment outcomes for complex trauma. Lastly, meta-regression results indicate a linear relationship between intervention intensity and symptom improvement (R²=0.45, p<.001). These findings expand on previous research by Thompson et al. (2021) and Al-Krenawi (2022) by identifying specific effective intervention components within the Gaza context. Additionally, the discovery that a phased approach integrating community support with protocol-based treatment yields optimal outcomes presents a novel contribution not previously addressed in meta-analyses.