Factors contributing to the occurrence of promiscuous sexual behavior include internal and external elements. Internal factors include low self-control, lack of religious understanding, and low sexual knowledge. External factors include family and peers; peer association can influence both positive and negative behaviors. Positive behaviors include participating in beneficial activities with peers, while negative behaviors include violating social norms, such as having casual sex. This research design uses an analytic correlation approach, with the aim of finding the relationship between variables, data collection is done by questionnaire. Using the chi square formula with the help of SPSS, 125 students were asked to answer. The results showed that of the 125 study respondents, most were 21 years old, 36.8 percent, and the majority were female, 58.4%. In addition, the results of the analysis showed that 46% of the respondents showed a good level of knowledge, while 47% showed sufficient attitude and preventive behavior. Conclusion: There is a correlation between knowledge and preventive behavior of promiscuous sex.

Ferritin is considered a protein that contains iron and includes two types of subunits: ferritin light chain (FTL) and ferritin heavy chain (FTH), which increases when inflammation increases, especially in the heart and kidneys, and helps in converting ferrous iron into iron. The light subunit is present in the liver and spleen and has a role in storing iron (1). Coronavirus (COVID-19) caused by the new coronavirus SARS-CoV-2 is a disease It is new to humanity, as it is accompanied by symptoms during the disease, including blood abnormalities, with activation of the immune system and phagocytic monocytes, and damage to the lungs. In our study, we showed that ferritin is an indicator of the severity of the disease and mortality (2). Acute respiratory syndrome (Coronavirus), which causes pneumonia and damages the heart, liver, and kidneys, is caused by the appearance of acute inflammatory cytokines that lead to death (3). A cytokine is a small protein that transmits messages to help stimulate the body’s immune response, and its rise causes increased inflammation, and these Cytokines secreted by macrophages (TNF-?, IL-10, IL-6) where there is high inflammation in the plasma. An indicator of the progress and severity of the disease (3).

Sunlight is the main source of energy for life, but ultraviolet radiation can have negative impacts on the skin, such as sunburn, pigmentation, wrinkles, premature aging, and the risk of skin damage due to excessive exposure. One way to protect the skin from these effects is to use sunscreen. Carrots contain antioxidant compounds that can bind free radicals and prevent cell damage due to oxidation, so they have the potential to be used as a natural ingredient in making sunscreen. This research aims to formulate and test the physical properties of carrot extract lotion as a sunscreen and determine the extract concentration that has the optimal Sun Protection Factor (SPF) value. The method used is experimental by making lotion formulations, testing their physical properties, and measuring the SPF value of each formulation. The research results showed that the KN, F1, F2, and F3 lotion formulations had a semi-solid form which met the formulation requirements. However, KN's SPF value is only 1.23 which does not meet sunscreen standards. Meanwhile, F1 has SPF 8.3 (extra effect category), F2 with SPF 15.06 and F3 with SPF 24.1 (ultra category). F3 shows the best results because with SPF 24.1, this formulation is close to SPF 25 which can protect the skin for up to 4 hours with twice daily use. The higher the concentration of carrot extract, the better its effectiveness in lotion formulation as a sunscreen.

Technicians in radiology departments are continuously exposed to ionizing radiation, which can affect biological systems. This study aimed to investigate the effects of low-level ionizing radiation (IR) on antioxidant enzymes and blood components in radiology personnel. The study involved forty participants aged 30 to 45 years, divided into three groups: G1 as the control group (n=10), G2 consisting of 15 radiologists, and G3 comprising 15 radiology technology workers. Participants in G2 and G3 had work experience ranging from 5 to 15 years and were employed in X-ray and CT scan departments at General K1 Hospital, Kirkuk. The measured parameters included white blood cells (WBCs), platelets, and lymphocytes, as well as malondialdehyde (MDA), superoxide dismutase (SOD), total antioxidant capacity (TAC), and albumin as indicators of redox status. The results showed a significant increase in MDA levels among radiology workers compared to the control group, while SOD, TAC, and albumin levels decreased (P<0.05). Additionally, radiation-exposed workers had a higher mean count of WBCs and lymphocytes than the control group (P<0.05), whereas platelet levels were significantly lower (P<0.05). This study indicates that occupational radiation exposure can cause short-term changes in blood cells and increase the circulating redox state in healthcare workers operating in CT and IR environments compared to those not exposed to radiation. These findings highlight the importance of regular health monitoring for radiology personnel to mitigate potential long-term effects of radiation exposure.

Diabetes mellitus is a chronic disease that requires proper management, including the use of conventional and alternative medicines such as herbal medicines. Patient knowledge about the benefits, risks, and potential interactions of herbal medicines with conventional medicines is very important to prevent complications. Objective This study aims to describe the level of knowledge of diabetes patients about the use of herbal medicines, including the benefits, risks, and interactions with conventional medicines at the Kebondalem Health Center, Pemalang Regency. This study uses descriptive observational analytic Data were collected through questionnaires distributed to diabetes patients who were treated at the Kebondalem Health Center. Data analysis was carried out quantitatively with percentages to measure the level of patient knowledge.

Blood pressure that is higher than normal is known as hypertension. This is a disease to be wary of because it has no signs and symptoms. Recurrence experienced by a person more than once with characteristics that occur frequently and are usually unpleasant. Several factors that influence compliance with treatment, family history, stress, diet compliance. This research aims to identify factors that play a role in the occurrence of relapse in hypertension patients. This research uses a quantitative approach with a descriptive method, which aims to describe the phenomenon in a certain population. Data were collected through the MMAS-8, PSS, and DASH questionnaires from 140 respondents selected using purposive sampling techniques. Based on the results of research from 140 respondents suffer from hypertension, it can concluded that majority were 57 people (40.7%), 76 people were female (54.3%), 137 people were married (97.9%), 53 people had a high school education level. people (37.9%), the longest duration of suffering from hypertension is 1-5 years as many as 62 people (44.3%), the occupation of respondents who work is 86 (61.4%), genetics and family history are the most many families, 88 people (62.9%), 79 people (56.4%) were moderately compliant with medication, 105 people were moderately stressed (75.0%), and 132 people were compliant with diet (94.3%). The results of this research revealed that a number of factors that contribute to recurrence in hypertensive patients include age, gender, marital status, education level, duration of illness, family history, compliance with treatment, stress levels, and compliance with diet.

Essential oils of Marjoram (Marjorana hortensis) has been evaluated for possible antioxidant activity. Essential oils were hydrodistilled and the chemical composition of volatile fraction was determined by GC. ?-Terpinene, sabinene, ?-phellandrene, terpinen-4-ol and di (2-ethylhexyl) phthalate were the major constituents of Marjoram.  The reducing power of essential oils of Marjoram was measured by the ferricyanide method. Different concentrations of Marjoram oil (MO) 25, 50, 75, 100 and 200 ppm were investigated. Higher absorbance at 700 nm of the reaction mixture indicated greater reducing power. The reducing power of an antioxidant is an important parameter reflecting one aspect of its antioxidant properties. The obtained results revealed that increasing the antioxidant capacity is MO in all tested concentrations.   The antioxidant capacity of fat-soluble antioxidant was expressed as equivalents of ?-tocopherol (nmol/g oil) using a molar absorption coefficient of ?-tocopherol (?= 4.0 × 103 M-1 Cm-1. The percent of H2O2 scavenging activity of the tested EOs increased in the MO at all tested concentrations. There was a significant difference among all EOs samples in the percent of H2O2 scavenging activity. a positive correlation has been observed between concentrations and antioxidant activity for 3 days' test period. There were significant differences among the tested EOs in their antioxidant activities. For 3 days, the antioxidant activity of the tested EOs decreased statistically in MO. BHT on the peroxide value of sunflower oil as mmol eq O2/kgoil in the seventh day

Drug interactions can occur when drugs are administered simultaneously with other drugs, both pharmacologically and clinically. This study aims to identify drug interactions that occur in prescriptions with patients experiencing endocrine system disorders for the period July 2024 at Hospital X, Bandung City. Endocrine disorders, involving hormonal dysfunction such as that of the thyroid, adrenals, or pancreas, can affect the pharmacokinetics and pharmacodynamics of drugs, thereby increasing the risk of interactions. This research method involved randomly collecting two prescriptions per day, with a total of 60 recipes analyzed. The results of the assessment showed that there were 15 potential drug interactions with a percentage of 25%, consisting of one minor interaction (6.67%), 15 moderate interactions (93.33%), and no major interactions were found.

Background: Preterm labor (PTL) remains a major global health concern, contributing significantly to neonatal morbidity and mortality. Asymptomatic bacteriuria (ASB), has been implicated as a predisposing factor to PTL. This research investigates association between ASB and PTL, emphasizing inflammatory mediators such as high-sensitivity C-reactive protein along with tumor necrosis factor- ?. Methods: This observational case-control study was conducted at Tikrit Teaching Hospital, Iraq, involving 100 pregnant women (50 PTL cases and 50 full-term controls). Demographic, clinical, and laboratory data were collected. Urine cultures identified bacterial isolates. In addition, levels of TNF-? and hs-CRP in serum were measured using ELISA. Statistical analyses were performed using SPSS.  Results: ASB was significantly associated with PTL, with 30% from PTL cases having a positive urine culture compared to 8% in controls (p = 0.009). Escherichia coli was the predominant pathogen (53%). TNF-? and hs-CRP levels were significantly elevated in PTL cases (p < 0.001), suggesting an inflammatory pathway in PTL pathophysiology. Conclusions: ASB is a significant risk factor for PTL, likely mediated by systemic inflammation. Routine ASB screening and targeted antimicrobial therapy may reduce PTL risk. Further study is required to explore the mechanistic connections amongst microbial infection and inflammatory responses in PTL. 

The adrenal cortex synthesis the steroid hormone dehydroepiandrosterone (DHEA), has a significant effect on diabetes mellitus. Our study targeted to estimate the relationship between serum levels of DHEA sulphate (DHEAS) and the risk of CAD complication for T2DM in men. Ninety Iraqi male subjects were divided into three groups. Each group has thirty people: thirty people type 2 with diabetes mellitus, thirty person type 2 diabetes mellitus patients with CAD complications, and the control group has thirty healthy people. A significant decrease (p<0.01) of DHEAS, was observed in T2DM with CAD (120.8 µg/dl) compared to both T2DM (141.26 µg/dl) and the control group (239.86 µg/dl). Meanwhile, an increased coronary risk index in T2DM with CAD (10.68) compared to both T2DM (7.56) and control group (4.41) was observed. These findings were confirmed by the negative correlation of DHEAs with coronary risk index. We suggested that a decreased level of DHEAS value may be a beneficial sign for future CAD in patients with T2DM.