This research begins with the understanding that parenting styles are one of the key factors influencing children's behavior, personality, and socio-emotional development. Thus, positive behavior in children largely depends on the application of appropriate parenting styles. The method used in this research is a descriptive design. The sample was taken using total sampling technique, with a total of 64 respondents. The instrument used in this study was a questionnaire. The results showed that the majority of the parenting style applied was democratic, with 64 respondents (100%), authoritarian with 13 respondents (20%), permissive with 17 respondents (26%), 14 parents applied two parenting styles, and 8 parents applied three parenting styles. **Conclusion:** This research is expected to serve as a reference for maximizing the implementation of effective parenting styles according to the child's developmental stage, which will have a more positive impact on the child's overall growth and development.

The combination of hormone treatment and genetic liabilities in transgender women leads to a complicated situation for breast cancer growth particularly linked to BRCA1 mutations. Gender-affirming treatment relies heavily on estrogen and causes intense cell growth and differentiation in breast tissue driven by estrogen receptor mechanisms. Mutations in BRCA1 lead to weak DNA repair processes which enhance an individual's vulnerability to cancerous changes. Rodestrogens enhance the functioning of proliferative pathways like PI3K/AKT and MAPK pathways in cells with dysfunctional BRCA1. This collaborative action elevates the threats posed by benign growths such as fibroadenomas leading to invasive breast cancer. By affecting the expression of vital regulatory proteins linked to cell proliferation estrogen further compromises the genomic integrity in cells harboring BRCA1 mutations. The hormone environment influenced by exogenous estrogen therapy can shape the tumor microenvironment for better cancer progression and metastasis. Comprehending the relationship between estrogen signaling and pathways related to BRCA1 is important for identifying the enhanced risk of cancer in transgender women using hormone therapy. This detailed study aligns recent discoveries regarding genetic vulnerability and hormonal impacts with cell mechanisms to reveal a detailed insight into breast cancer progression in these individuals. The study emphasizes the necessity for custom-designed cancer screening methods and targeted treatments to help mitigate risks and support transgender care. Understanding these pathways greatly enriches our knowledge of hormone-induced carcinogenesis among those who carry certain genetic markers while also guiding the creation of personalized care for transgender women at enhanced risk of breast cancer.

Implementation is a process of putting something into practice which is influenced by internal and external factors. Implementation of occupational health and safety in hospitals concerns the nursing workforce, work methods/methods, work tools, work processes and the work environment which includes improvement, prevention, treatment and recovery. The aim of this research is to determine the relationship between knowledge, motivation and compliance of nursing staff with the implementation of occupational safety and health at Mega Buana Palopo Hospital in 2023. The method uses a quantitative type of research using analytical observational methods, using a cross sectional approach. The sample in this study amounted to 76 respondents. The sampling technique uses random sampling with research instruments, questionnaires and observations. Data analysis used the Fisher exact test and chi-square test. Factors related to the implementation of occupational health and safety for nurses were a good level of knowledge, namely 68 respondents (89.5%), 74 respondents (97%) were motivated and complied with implementation of occupational health and safety, namely 42 respondents (55.3%). The results of the study showed that there was a relationship between knowledge (p= 0.012), motivation (p = 0.034), and compliance of nursing staff (p= 0.016) with the implementation of hospital occupational health and safety. The level of knowledge, motivation and compliance of nursing staff is related to the implementation of occupational health and safety in hospitals

Fractures are emergency conditions that must be treated quickly and accurately and in accordance with fracture management procedures. In general, clients with fractures must undergo surgery which in addition to causing pain also affects activity. After surgery, rehabilitation is needed to prevent contractures. Nursing care for patients with upper/lower extremity fractures must be prioritized and focused on providing comfort, preventing complications, and achieving optimal rehabilitation in rehabilitation. Patients are taught mobilization or movement exercises, namely Passive Range of Motion (ROM). Purpose: To determine the Effectiveness of Passive ROM Exercise in Postoperative Patients with Upper/Lower Extremity Fractures on Length of Stay at Sukoharjo Regional General Hospital. Design: This researcher studied the type of experimental research. The method used is a case study. Results: the results of the study showed that the majority of Active ROM respondents were treated for 2 days with a frequency of 5 respondents. Then the results showed that there was a difference in the effect of passive ROM on the length of stay for fracture patients at Sukoharjo Regional General Hospital.

Background : The problem found at the Sayang Bunda Makassar General Hospital was a decrease in patients after the end of COVID-19 in 2023, there were visit data of 147 patients in January – July. Objective : The purpose of this study is to determine the role of Public Relations in increasing the existence of the hospital. Method : This type of research used qualitative research methods. Methods collected documentation data and in-depth interviews to Result : The research results obtained at the general hospital unfortunately have not been fulfilled in terms of social activities which were only held in 2020, as for the results of observations of social activities and published on social media, this provides satisfaction that the service at the general hospital unfortunately has not collaborated with BPJS insurance, as for communication through media, it has not been fulfilled so that the internet is widely used, social media such as Instagram, as well as the educational dimension when carrying out activities.   such as handling mass circumcisions or providing direct health services. Suggestion : The hospital needs to improve marketing management by digitalizing marketing, promoting health through electronic media as well as re-organizing social activities, improving facilities and infrastructure as well as access to payment via card (JKN-KIS) at Sayang Bunda General Hospital.

Conjunctivitis is an inflammation of the conjunctiva, the mucous membrane covering the back of the eyelids and the eyeball, which can be acute or chronic. This condition is characterized by conjunctival hyperemia, edema, and discharge. Causes of conjunctivitis include bacteria, chlamydia, allergies, viruses, and systemic diseases. The incidence of conjunctivitis varies by age, sex, and season. Although slightly more common in women in emergency departments, the seasonal pattern of conjunctivitis is consistent across regions. Allergic conjunctivitis, which affects 15-40% of the population, is most common in the spring and summer. Bacterial conjunctivitis is most common from December to April. Acute bacterial conjunctivitis is generally self-limited, with symptoms lasting 1-3 days if treated appropriately, but can last 10-14 days if left untreated. Staphylococcal and gonococcal conjunctivitis can lead to chronic complications or serious problems such as corneal perforation. Viral conjunctivitis usually gets worse in 4-5 days and resolves in 1-2 weeks. Complications are rare but can include corneal problems and life-threatening conditions such as meningitis or sepsis.

Cyclodextrin inclusion complexes have been widely used in the pharmaceutical industry to improve drug solubility and bioavailability. Analysis of these complexes using HPLC requires the development of appropriate and validated methods. To analyze and compare various HPLC methods used for the analysis of cyclodextrin inclusion complexes, and to identify challenges and trends in method development. A literature review was conducted of articles published in the last 10 years, focusing on HPLC methods for the analysis of cyclodextrin inclusion complexes. Parameters compared included column type, mobile phase composition, flow rate, and detection method. The majority of studies used C18 columns with varying lengths and particle sizes. The composition of the mobile phase varied, reflecting the diversity of properties of the complexes analyzed. The flow rate was generally 1.0 mL/min, with the exception of the HPLC/MS method. Detection methods included UV-Vis, PDA, fluorescence, and mass spectrometry. The main challenges included the dynamic equilibrium of the complexes and stability during analysis HPLC method development for the analysis of cyclodextrin inclusion complexes requires optimization of various parameters to overcome specific challenges. Future trends are towards the use of advanced technologies such as UHPLC and high-resolution mass detection.

The community service project aims to enhance public knowledge and skills in providing immediate assistance during cardiac emergencies. Conducted in collaboration with the Indonesian Emergency and Disaster Nurses Association (HIPGABI) North Sumatra and the Regional Crisis Center Team North Sumatra, this program focuses on training participants in the fundamental techniques of Basic Life Support (BLS), including cardiopulmonary resuscitation (CPR) and the use of automated external defibrillators (AEDs). The training is specifically designed for the congregation of HKBP Resort Kwala Bekala Church. The involvement of HIPGABI North Sumatra and the Regional Crisis Center Team North Sumatra brings expertise and professionalism, ensuring that the training adheres to national standards and best practices in emergency response. The outcomes of this training are expected to strengthen community resilience and preparedness in dealing with health emergencies in Medan and the surrounding areas.

Many teenagers now spend most of their time playing gadgets. The teenagers can spend all day playing gadgets. The teenagers can spend all day playing gadgets. Using for a long time causes them to take about 60 minutes longer to fall asleep than usual, resulting in them experiencing insomnia. The purpose of this study is to determine the relationship between the duration of gadget use and the incidence of insomnia in adolescents at Betzata ABD Leilem Junior High School. Sampling in this study with the Slovin formula, as many as 62 respondents. Data collection using questionnaires via google forms. The data analysis in this study was univariate and bivariate analysis (Chi square test) measuring the relationship between each variable with a vale?= 0.05. The results of the study were obtained, there was a relationship between the duration of gadget use and the incidence of insomnia with a value = 0.06 (value < 0.05). The conclusion in this study is that there is a relationship between the duration of gadget use and the incidence of insomnia in adolescents at Betzata ABD Leilem Junior High School.

Background : One of the most prominent negative impacts in patients with kidney failure undergoing hemodialysis is fatigue. Breathing and range of motion exercises are therapies that can be applied to reduce fatigue in patients with chronic kidney failure. Objective: to provide breathing and range of motion exercise interventions in patients with chronic renal failure. Method: used in this study is a case study. Assessment of Mrs. S conducted for 3 consecutive days. Results: After the intervention for 3 days, the results showed that the level of fatigue and anxiety in Mrs. S decreased. Conclusions and suggestions: The interventions given have an effect on reducing the level of anxiety and fatigue of patients. It is expected that nurses can provide optimal nursing care to patients with chronic kidney failure to improve the quality of life of patients.