Objective: We aimed to explore that the association of irisin with various anthropometric and metabolic parameters in obese diabetics and non-diabetics Iraqi women. Methods: Eighty obese Iraqi women participated in this cross-sectional study grouped into 40 obese and 40 obese diabetics. The correlation coefficient between circulating irisin levels and metabolic parameters were performed. Results: Serum irisin levels in obese group showed highly significant positive correlations with body weight, WC, BMI, FPG, fasting insulin (FI), HOMA-IR and glucagon (r=0.8684, P> 0.0001 ; r = 0.8104, P> 0.0001; r = 0.8285, P <0.0001; r = 0.5876, P> 0.0001?; r = 0.5283, P> 0.0005?; r = 0.0005, P <0.0001; r = 0.5244, P> 0.0005) respectively,  and significant negative correlation ?with FPG, FI and HOMA-IR (r=-0.3246, P<0.041; r=-0.7903, P<0.0001; r=-0.6105, P<0.0001) respectively. Stepwise regression results showed that body weight, FPG, HOMA-IR and glucagon had significant independently related with irisin (?=?2.3150, P<0.0001; ?=-?1.2200, P=?0.0002; ?=?21.8760, P=0.02?; ?=?-20.9800, P<?0.005; ?=?0.0468, P=0.037) respectively. Conclusions: Irisin had a strong positive correlation with anthropometric parameters. Irisin independently associated with body weight, glucagon, HOMA-IR and FPG

Background: Post partum is a condition where the reproductive organs are restored to their pre-pregnancy state. The process of childbirth almost 90% experience perineal tears. To be able to accelerate perineal wounds can be with pharmacological and non-pharmacological measures, one of which is non-pharmacological action with kegel exercise, kegel exercise is pelvic muscle training by contracting the muscles. Objective: to describe the results of observations of wound healing and changes in wound characteristics in post partum women. Methods: This research is a case study research using descriptive methods, namely by observing 2 (two) respondents of post partum women with perineal rupture. Performed for 7 days of application and wound evaluation on day 8. Results: This application shows that before Kegel exercise was performed, both respondents' perineal wound conditions were classified as moderate wounds, namely wet wounds, perineal closure, no signs of infection. After evaluation on the eighth day, the wound condition of Mrs. D and Mrs. E was classified as a good wound, namely dry perineal wounds closing and no signs of infection. Conclusion: There are differences in wound healing and changes in perineal wound characteristics in postpartum women.
 
 

AEFI or Post-Immunization Adverse Event is a medical condition that is assumed to be related to immunization. Reactions that arise due to AEFI include high fever, abscesses/festering, seizures. The 2018 Lampung Provincial Health Office report noted that 32.6% experienced AEFI with the largest number being those experiencing high fever, namely 29.5%, festering 8.3%, seizures 0.97%, and others 0.57%. Reducing or controlling and controlling fever in children can be done in various ways, including pharmacologically and physically (non-pharmacologically), namely by using heat energy through conduction and evaporation methods. the effect of onion compress on reducing the baby's body temperature during fever after DPT immunization at PMB Yunita Vero Miza Lampung in 2024. Type of analytical survey research with a Post test Only Control Design approach. The research results showed a decrease in baby's body temperature after DPT immunization in the intervention group and control group after being given shallot compress with an average difference of 1.060. The results of the paired t-test obtained a p value = value 0.000 (p <0.05). there is an effect of onion compress on reducing the baby's body temperature during fever after DPT immunization at PMB Yunita Vero Miza Lampung

One of the most significant species in the Lamiaceae family, thymus vulgaris isendemic to the Mediterranean region and is used widely for both medicinal andculinary purposes. this study aims to evaluate the use of natural antimicrobials asan alternative therapy because the long-term use of antibiotics in the treatment ofacne has resulted in the formation of resistance. It may be inferred that Thymusvulgaris (T. vulgaris) extracts have the ability to suppress the test bacteria in theplan, indicating that they may be used as antimicrobial agents against pathogenicbacteria.

Dysmenorrhea is a gynecological complaint resulting from an imbalance of the hormone progesterone in the blood, resulting in pain. The impact of menstrual pain is very diverse, including young women being unable to walk, having difficulty sleeping, being in a bad mood, losing concentration in doing something, and so on. Gymnastics is a relaxation technique for experiencing dysmenorrhea. To find out nursing care for adolescents with reproductive disorders, dysmenorrhea, the design used in this scientific report is a case study. This case study results from the application of Evidence Based Practice (EBP), client K experienced moderate dysmenorrhea pain on a scale of 4 after being given the intervention, decreasing to mild pain on a scale of 2, client R experienced mild dysmenorrhea pain with a pain scale of 3 after being given the intervention, decreasing to mild pain on a scale of 1 and client S experienced mild dysmenorrhea pain with a pain level of 3 after being given the intervention, decreasing to no pain on a scale of 0. Applying Evidence Based Practice (EBP) it can be concluded that dysmenorrhea exercises can reduce the dysmenorrhea pain experienced by young women during menstruation.

Background: as we know every child will experience a period of growth and development. The growth and the development could be seen from some aspects such as: language, fine motor skills, gross motor skills, social personal aspects. This period is sensitive one; the children will be sensitive to receiving all stimuli given by their parents or their environment. The study aims to obtain the description of the development of preschool age children at the Futuhiyyah Doro Islamic Kindergarten.Method: it is a quantitative descriptive with a total sampling technique as the technique of data collecting; 82 respondents. The instrument applied was the Pre-Developmental Screening Questionnaire as the development measuring tool. Besides, the data analysis used was univariate in the form of a percentage frequency distribution.Results: the result stated characteristics of preschool age children at the Futuhiyyah Doro Islamic Kindergarten are the average age is 68 months, 47 respondents (57.3%) were female and 35 (42.7%) were male. Furthermore, at that age, there were 72 respondents (87.8%) who had appropriate development and 10 respondents (12.2%) who doubted it.Conclusion: Description of the development of preschool age children at the Futuhiyyah Doro Islamic Kindergarten, there were 72 respondents (87.8%) with appropriate development.
 
 
 

Hydroquinone is a compound that is often used in skin whitening beauty products. According to BPOM 2007, the use of hydroquinone at levels above 2% can cause skin disorders, namely hyperpigmentation which can lead to skin cancer. This research was conducted to qualitatively analyze the hydroquinone compound found in skin whitening soap which does not have a BPOM number. The aim of this research is to determine the presence of hydroquinone compounds contained in skin whitening soap samples and to determine the differences in Rf values ??resulting from the comparison of the concentrations of the mobile phase used. Qualitative analysis was carried out by calculating the Rf value of paper chromatography using a comparison of variations in mobile phase concentration, namely 50% ethanol: chloroform (1: 1) and 90% ethanol: chloroform (1: 1). The analysis results show that the standard Rf value of hydroquinone from the eluent of 50% ethanol and chloroform is 0.46, where this Rf value is the same as the Rf value from sample number 5, namely 0.46. Meanwhile, the Rf value using 90% ethanol and chloroform eluents in sample No. 5 is 0.67, which is not the same as the standard Rf value, namely 0.56. Of the whitening soap samples, 1 sample showed a positive result containing hydroquinone.

The decline in cognitive function can be influenced by various factors, both individual and environmental. Individual factors include age, gender, level of education, genetic factors, and medical history. Meanwhile, environmental factors include social engagement and activities, both physical and cognitive activities. This research aims to investigate the Relationship between Social Interaction and Physical Activity with Cognitive Function in the Elderly Population in Neighborhood 05 of Cilangkap Subdistrict, Tapos District, Depok City. The method used in this research utilizes a quantitative approach with a cross-sectional design, involving a sample of 55 respondents. The research results showed that the majority of respondents had good social interaction, totaling 32 respondents out of the total respondents. Of these, 23 (71.0%) respondents had a normal cognitive function, while 9 (28.1%) respondents experienced moderate cognitive impairment. Additionally, the majority of respondents with good physical activity and normal cognitive function amounted to 22 respondents (75.9%), while respondents with good physical activity and moderate cognitive impairment numbered 7 respondents (24.1%). In conclusion, the majority of respondents with good social interaction and good physical activity tended to have normal cognitive function.
 
 

In the 1970s bedbug infestation was thought to have disappeared, but since the 2000s, the appearance of bedbugs has been reported worldwide. Studies on bed bugs were carried out in several residential locations in Palangka Raya. This study aims to determine the existence of bed bugs in residential areas and the biological aspects of bed bugs. Survey and collection of bedbugs are carried out in densely populated areas. The results of the study showed that out of 20 houses observed, there were 2 houses that were identified with the presence of bed bugs. The only species of bed bug found is the, Cimex lecturarius. Bed bug infestation is observed in the beds. This shows that there is a potential for bed bugs to cause itching on the skin and allergic reactions in the occupants of the house. The population of bed bugs has the opportunity to spread to other residents' settlements.

Flooding is an event or event that results in the submergence of an area or land due to an increased volume of water. Flooding is caused by climate change, lack of water reception upstream area due to the many buildings, residential houses on the banks of the river and the lack of public awareness to maintain the cleanliness of the river. Flood disasters have a negative impact on individuals, communities and the environment. For individuals can be at risk of drifting, injuries, injuries, to other health problems such as digestive disorders, skin diseases, to infections. This impact can be reduced by improving community preparedness in facing disasters. All activities are carried out to anticipate disasters through organizing and using appropriate scarce disaster management in the preparedness phase. The purpose of this study is to determine whether there is a relationship between flood preparedness knowledge and the level of community anxiety in Wonasa Tanjung Village. This research was conducted with Descriptive Analytic method with Cross Sectional approach. There were 106 Subjekts. Data collection is carried out using questionnaires. Furthermore, the data was analyzed with the Chi-squaer test with a meaning level (a).0.05. The results of the study using the Chi-squere statistical test obtained a p value Value = 0.01 where the p Value value <a = 0.05 The results of this study show that there is a relationship between flood disaster preparedness knowledge and the level of anxiety of the community in Wonasa Tanjung Village. The conclusion of this study is that there is a relationship between flood disaster preparedness knowledge and the level of community anxiety in Wonasa Tanjung Village. Advice for the Wonasa Tanjung environment is to maintain cleanliness and no longer throw rubbish in the river.