Computational thinking is the ability to solve problems and design systems using concepts and techniques generally associated with computers and computer programming. The aim of this research is to conduct a literature review, namely to determine the application of computational thinking in mathematics learning. The technique used is the Systematic Literature Review (SLR) strategy. SLR is a research method that aims to identify, study and interpret data in journals systematically with specified stages. The conclusion obtained from the research results is that the application of computational thinking in mathematics learning can be done using four foundations of computational thinking, namely: (1) Decomposition, namely the problem is divided into small parts, (2) Pattern recognition, namely the process of identifying patterns or sequences of problems, (3) Abstraction, namely consideration of the important parts of a problem, and (4) Algorithm, namely a series of instructions for solving the problem. Examples of its application include the use of interactive mathematics software, mathematical simulations, problem-based learning with technology, adaptive learning and the use of educational games.