Ankle sprain is an acute injury to the musculoskeletal system involving the ligaments in the ankle. An ankle sprain is a stretching or tearing of the ligaments in the ankle (ankle). Ligaments function as connective tissue between bones that can help control range of motion and stabilize bones when moving. When the ligaments in the ankle are injured or torn, it causes loss of movement stability and can cause pain. Ankle sprains often occur in sports athletes and high heel users who use their feet a lot.