The management and care of wounds play a crucial role in the healing process. Improper wound management can lead to infections, slow down the healing process, and even cause post-healing disabilities. Therefore, increasing knowledge about wound care is essential, especially in initial treatment, by conducting wound care training to prevent infections.The training was provided to the administrative staff and youth of the St. Francis of Assisi Church in Tebet. It was conducted using two methods: theoretical and practical. Participants were given pre- and post-training tests to assess their understanding and knowledge before and after the training. A total of 22 participants attended the wound care training to prevent infections. There was a significant increase in the average test scores after the training. It can be concluded that the training improved participants' understanding and knowledge of wound care to prevent infections.

Dementia is a complex neurodegenerative syndrome characterized by cognitive decline, including memory impairment, difficulty in thinking, and social interaction, which can affect daily activities. This condition is often caused by other diseases, including Alzheimer’s disease, vascular dementia, Lewy body dementia, and frontotemporal dementia, each with unique pathological mechanisms. Alzheimer’s disease, the leading cause of dementia, involves the accumulation of beta-amyloid plaques and tau tangles that disrupt neuronal function and trigger chronic inflammation. Vascular dementia results from impaired blood flow to the brain, while Lewy body dementia is associated with the misfolding of alpha-synuclein protein. Meanwhile, frontotemporal dementia is linked to the accumulation of tau or TDP-43 proteins, causing degeneration of the frontal and temporal lobes. Aging is the primary risk factor for dementia through the process of inflammaging, a low-grade chronic inflammation caused by persistent activation of the immune system. Inflammaging accelerates neurodegeneration by increasing oxidative stress, mitochondrial dysfunction, and the accumulation of pathological proteins. Additionally, neuroinflammation plays a crucial role by over activating microglia, which exacerbates neuronal damage. The combination of inflammation as both a trigger and a consequence create a pathological cycle that accelerates the progression of dementia. Preventive strategies include managing modifiable risk factors such as hypertension, diabetes, obesity, and adopting a healthy lifestyle, alongside developing therapies targeting inflammaging and neuroinflammation. A deeper understanding of these pathophysiological and inflammatory mechanisms is essential to support the development of multidisciplinary interventions to reduce the global burden of dementia.
 

This study aims to determine the simultaneous and partial effect of work discipline and work experience on teacher performance at the Mas Athoriyah Cikatomas Foundation, Tasikmalaya Regency. The research method used in this study is a quantitative method with a census approach. The population in this study amounted to 40 teachers at the Mas Athoriyah Cikatomas Foundation, Tasikmalaya Regency. The type of data used in this study is primary data obtained through questionnaires. The data testing technique used in this study uses the validity test, reliability test and classic assumption test. Data analysis in this study used multiple regression analysis using SPSS software version 25. The results of this study indicate that work discipline and work experience simultaneously have a significant effect on teacher performance at the Mas Athoriyah Cikatomas Foundation, Tasikmalaya Regency. Work Discipline partially has a significant effect on the Teacher Performance of the Mas Athoriyah Cikatomas Foundation, Tasikmalaya Regency, and work experience partially has a significant effect on the Teacher Performance of the Mas Athoriyah Cikatomas Foundation, Tasikmalaya Regency.