Hospitals must be able to deal with the dynamics of rapid change in the digital era, hence the need for digital transformation. Retention towards digital transformation in hospitals can take many forms, especially among medical and administrative staff. This study aims to evaluate the success of digital transformation at Cahaya Medika Hospital using the DeLone & McLean Model. This research method is quantitative explanatory research. The sample in this study were health workers, administration and medical support at Cahaya Medika Hospital totaling 127 respondents. Data collection using questionnaires and descriptive analysis techniques using the SEM-PLS method. The results showed system quality, information quality, and service quality influenced directly and indirectly on net benefits through use and user satisfaction on officers at Cahaya Medika Hospital. These results have theoretical implications that support theory and previous research. Managerially, it is expected to provide input for Cahaya Medika Hospital management to improve the success of digital transformation in hospitals. These efforts can help increase the level of system usage and user satisfaction which ultimately increases net benefits for the hospital. There is a significant influence of system quality, information quality, and service quality on net benefits through usage and user satisfaction on the success of digital transformation in RS Cahaya Medika Tambun Utara.