Coronary heart disease (CHD) is characterized by heart attacks caused by atherosclerosis. In 2024 at Prof. dr. Chairuddin P. Lubis Teaching Hospital Medan, it was 178 people (31%) were productive age patients with CHD receiving outpatient treatment. The purpose of the study was to determine the factors associated with the incidence of CHD in patients aged 25-59 years at Prof. dr. Chairuddin P. Lubis Teaching Hospital Medan in 2025. This study uses quantitative research with Cross Sectional. Sampling technique used accidental sampling with total 82 respondents. Data were collected through interviews using questionnaires and medical records. The results of the bivariate analysis with the chi-square test showed that factors related with CHD were age (p=0,007), gender (p=0,004), physical activity (p=0,022), smoking habits (p=0,009), hypertension (p=0,017), diabetes melitus (p=0,032), and cholesterol levels (p=0,003). There is no relationship between family history (p=0,734) and incidence of CHD. Recommendations for people of productive age to control the risk factors of CHD by regularly doing physical activity, not smoking, and periodically checking for blood pressure, blood sugar, and cholesterol levels.

Hypertension in pregnancy is one of the leading causes of maternal mortality, with a global prevalence of 5–10% (Khedagi & Bello, 2021). This study aims to analyze the effect of reproductive status—maternal age, gravidity, and parity—on the incidence of hypertension in pregnancy at Prof. Dr. Chairuddin P. Lubis Educational Hospital, Medan. A case-control design was employed with 96 respondents, consisting of 48 cases and 48 controls. Bivariate analysis revealed that pregnant women aged ?35 years have a 2.839-fold higher risk of developing hypertension compared to those aged <35 years (OR=2.839; 95% CI: 1.123–7.177; p=0.027). First pregnancy (primigravida) increases the risk by 2.742 times compared to multigravida (OR=2.742; 95% CI: 1.047–7.178; p=0.040), while nulliparous women have a 2.714-fold higher risk compared to those who have given birth (OR=2.714; 95% CI: 1.101–6.693; p=0.030). Multivariate analysis identified maternal age ?35 years and nulliparity as the most significant predictors (p=0.005). These findings align with studies by Wiranto & Putriningtyas (2021), Hinkosa et al. (2020), and Luo et al. (2020), which confirmed that advanced maternal age and nulliparity increase the risk of pregnancy complications. The novelty of this research lies in integrating all three reproductive status factors as simultaneous predictors of hypertension risk, providing a new perspective compared to previous studies focused on single variables. Based on these findings, early detection and targeted health education for high-risk mothers are strongly recommended.