This study was made to determine the influence of learning independence and the availability of educational facilities and infrastructure on student learning outcomes in universities. As for this study, a type of research with quantitative research methods along with descriptive analysis was used. All data were collected using a questionnaire measured using a Likert scale from value one to value five involving 100 random students as a sample in the study. Then, the data analysis technique used in this study is a linear regression technique, which consists of validity, reliability, normality, linearity, autocorrelation, multicollinearity, heteroscedasticity, f-test, t-test and determination coefficient test using the SmartPLS 4 software application. The results of this study show that there is a positive and significant influence between the independence of learning on learning outcomes, there is a positive and significant influence between the availability of educational facilities on learning outcomes, there is a positive and significant influence between the availability of educational infrastructure on learning outcomes, there is a positive and significant influence between learning independence and the availability of educational facilities and infrastructure together on learning outcomes.