This study aims to review the latest developments in medicinal chemistry and its prospects in the development of future treatments. Through a comprehensive literature study approach, this study analyzes the latest innovations in drug design and development, including the use of computational technology, nanotechnology, and biological target-based approaches. The results show that the integration of artificial intelligence and machine learning technologies with conventional medicinal chemistry techniques has opened a new paradigm in more efficient and precise drug discovery. Personalization of treatment based on patient genetic profiles, development of new antibiotics to overcome antimicrobial resistance, and nanomaterial-based therapies are important trends in contemporary medicinal chemistry applications. This study concludes that the future of medicine will be greatly influenced by advances in medicinal chemistry, with the main challenges being safety, regulation, and accessibility.More intensive multidisciplinary collaboration is needed between chemists, biologists, pharmacologists, clinical medicine, and informatics to optimize the potential of medicinal chemistry in the future medicine revolution.

The COVID-19 pandemic had a significant impact on UMKM. Social distancing has changed consumer behavior from conventional to digital. UMKM Shapro Official is an original automotive t-shirt vendor that was established in 2017. Shapro Official has difficulty in introducing and marketing products with a clear target consumer and competitive price competition. Sales promotions have not been managed optimally and sales data management is still manual (notes). Owners also have difficulty monitoring sales reports in real time. Website created using CMS Wordpress to help Shapro Official difficulties. The system development method is Rapid Application Development (RAD). System analysis method using fishbone diagram and system modeling using Unified Modelling Language (UML). The results showed that the existence of a website can help the management to manage promotions, sales and sales reports. Having a website makes sales targets focus and increase. 
 

Sekolah dasar merupakan tempat pembelajaran bagi siswa memperoleh pendidikan dasar. Pembelajaran merupakan suatu proses perubahan tingkah laku yang diperoleh melalui pengalaman individu yang bersangkutan. Kegiatan pengabdian ini bertujuan meningkatkan pengetahuan siswa Sekolah Dasar Negeri  Klabang dalam penerapan  pengelolaan buku dalam kehidupan untuk menunjang belajarnya. Metode yang digunakan melalui  penyuluhan dan pelatihan praktik bagi  siswa. Kegiatan diawali dengan mengajak siswa dalam menata buku dan menulis katalog buku serta cara menata buku-buku pada rak yang tersedia  secara konvensional.   Kemudian kegiatan dilanjutkan dengan  memberikan penyuluhan dan  praktik cara penginputan data buku serta melihat hasil laporan dalam menggunakan manajemen informasi perpustakaan sekolah berbasis komputerisasi. Setelah adanya kegiatan ini, siswa sekolah dasar negeri Klabang, mendapatkan tambahan pengetahuan, yang diharapkan memberikan dampak bagi siswa dalam mengimplementasikan dalam penataan buku yang di rumah masing-masing guna memudahkan siswa dalam mencari buku-buku pribadi secara efektif dan efisien yang digunakan belajar.