Hyperlipidemia is a condition in which lipid levels in the bloodstream (plasma) experience an imbalance in lipid levels, although it does not show severe symptoms but can trigger various serious diseases. Statins are used as the main therapy for antidyslipidemia, but with long-term use, statins cause various side effects such as muscle pain, muscle disorders and muscle discomfort. Indonesia has a variety of plants that have benefits for lowering blood cholesterol levels. To determine the potential of metabolite compounds contained in several plants as HMG-COA Reductase inhibitors, research can be carried out using molecular docking. The purpose of this literature study is to determine the comparison of compounds that have HMG-COA Reductase inhibitor inhibitor activity. The method used in compiling this literature study is from various national and international scientific articles published in the period 2020-2025. The natural compounds that have been studied have significant inhibitory activity against the HMG-CoA Reductase enzyme, namely from the 10 plants studied, Rhodomyrtus tomentosa has the best activity in inhibiting the HMG-CoA Reductase enzyme with an Affinity of the Binding value of -11.4 so that it has the potential to be further developed as a natural anti-cholesterol drug.

This study aims to analyze the content of life skills in life skills training activities at LKP Karya Prima. The method used is descriptive quantitative with data collection through closed questionnaires given to 20 active training participants. Data analysis was carried out using percentage techniques to identify the proportion of each life skills indicator. The results showed that vocational skills were the most dominant aspect with a percentage of 31%, followed by personal skills at 24%, academic skills at 23%, and social skills at 22%. This finding shows that the development of life skills at LKP Karya Prima emphasizes vocational skills, but still pays attention to personal, academic, and social aspects in a balanced manner. The four indicators complement each other in forming the participants' life skills as a whole

This study is motivated by the phenomenon that many micro and small business actors are trapped in easy online loans but pay high interest. In addition, in the business they own, product pricing is oriented towards general conditions so that labor costs are rarely taken into account. As a result, they often make mistakes in measuring business productivity which ultimately leads to business decline. The problems that are often faced are more in financial management due to low financial literacy, lack of experience in finance and lifestyle. This study aims to test and analyze the influence of financial literacy, financial experience and lifestyle on the financial management behavior of MSE’s actors. Data were obtained from questionnaires to 100 respondents which were processed using multiple linear regression analysis. The results of the study stated that financial literacy, financial experience have a positive and significant effect on financial management behavior while lifestyle does not have a significant effect on financial management behavior.

Anti-corruption education is one of the important elements in building the character and integrity of the younger generation. Given the negative impact of corruption that damages the country's social, economic, and political order, this education is an effective preventive means to avoid corrupt practices in the future. This paper aims to explore the concept of anti-corruption education, its role in shaping a generation with integrity, as well as its challenges and implementation strategies. The concept of anti-corruption education involves teaching the values of ethics, honesty, and responsibility that must be instilled from an early age. This education must be applied consistently through formal and non-formal curricula, and involve various parties, including educators, the government, and the community. The challenges faced in the implementation of anti-corruption education include a lack of understanding and awareness of the importance of this education, as well as a culture of corruption that has been internalized in various sectors of life. To overcome these challenges, it is necessary to adopt various implementation strategies, such as the use of technology and social media, as well as collaboration between educational institutions and civil society organizations. Through effective anti-corruption education, it is hoped that a young generation can be created who have integrity, are able to prevent corruption, and contribute to the development of a clean and transparent country.

The use of language on social media at this time, there are often various errors in word forms in morphology that are interesting to analyze. This happens because social media users such as Instagram express themselves freely without being bound by formal language rules. Social media is also a place where language rules are constantly changing, so that word forms often change. For example, the use of affixes or remixes in social media that is not in accordance with the rules, but is still understood by netizens in more informal communication. This study aims to analyze morphological errors such as affixation and reduplication in @dewiperssik9 Instagram views. The method used in this study is a qualitative descriptive method with a documentation observation approach. Data collected through recording and shooting on the Instagram site display @dewiperssik9 related to affixation and reduplication. The data that has been collected will be analyzed to find morphological changes or irregularities. The results of this study show that there are many errors in the use of affixation and reduplication. These errors include improper prefixes and syphilis, as well as differences in reduplication patterns. These findings show how changes in the use of language in the digital age, can help develop the study of linguistics on social media.

Muhammadiyah is an Islamic movement with the preaching of Amar Makruf Nahi Munkar which is based on Islamic faith and is based on the Qur'an and As-Sunnah. Many things drive the progress of this Muhammadiyah organization, such as the vision-mission, educational concept, goals, and curriculum that are mutually continuous so that Muhammadiyah can process well in the life of society. In Islamic education there are challenges that must be faced by Muhammadiyah because considering the development of Islam is very fast and also flexible and always relevant from time to time. One of the challenges to the development of Islamic education is the advancement of technology. The advancement of science and technology (iptek) requires all parties to be competent so as not to be eroded and crushed by the times. The negative and positive impacts of technological progress must be addressed with the right innovation. Innovation that can be applied by the Muhammadiyah organization is through the field of education. Education is a process that can shape human beings such as potential, personality, intelligence, noble morals, self-control, religion and skills needed in oneself and society.

The purpose of this study is to observe the cognitive development of early childhood in PAUD Sukacita, especially children aged 5-6 years, through learning activities that involve the introduction of body parts and the calculation of numbers. This learning activity is designed to assess children's ability to understand simple concepts, the courage to appear in front of the class, and numeracy skills. The results of the observation showed that the children's responses to the given activities were very different. Some children show good responses, show optimal cognitive development, and show high self-confidence. . However, there are children who have difficulty understanding the material or feel embarrassed when performing in front of their peers. The main causes of this variation are social anxiety, lack of prior stimulation, and differences in confidence levels. These results underscore the importance of methods that support children's emotional and social development and provide appropriate cognitive stimulation to help children maximize their potential.

Plans are a vital component in a government to achieve directed and sustainable development. This research aims to identify the importance of plans in managing resources, setting priorities, and creating transparency and accountability in government. The method used in this research is qualitative analysis based on literature reviews and case studies related to plan implementation in various governments, both national and local. The focus of this research includes the role of plans in resource efficiency, risk mitigation, and coordination between institutions. The research results show that governments that have thorough planning are better able to optimize the use of budget, labor and time compared to governments without clear plans. In addition, a good plan helps the government anticipate potential risks and challenges, as well as provide strategic solutions to face them. In terms of transparency, planning documents enable the public to monitor government performance, increase public trust, and support public participation in the development process. This research also found that plans that are inclusive and involve various stakeholders are able to create stronger synergy between institutions and maintain program sustainability even if there is a change in leadership. In conclusion, plans in government are not only a tool to direct development, but also an important instrument to ensure stability, effectiveness and efficiency. With a structured plan, the government can achieve development goals optimally and have a significant impact on community welfare. This research recommends strengthening planning capacity at all levels of government to improve the quality of governance and public services.

This research aims to analyze the ability of FMIPA Mathematics students at Medan State University (Unimed) in solving problems of convergence and divergence of real number sequences, as well as evaluating the effectiveness of using MATLAB software in supporting understanding of these concepts. This research is based on the aim of overcoming students' difficulties in understanding the concepts of convergence and divergence. The research method used was qualitative, with a sample of 20 students selected using purposive sampling. Data was collected through written tests and observations of the use of MATLAB which were distributed via Google Form in solving questions. The results show that 55% of students are in the "very understanding" category, with MATLAB proving to be very effective in making problem solving easier and deepening understanding.

This study aims to analyze the influence of cash turnover, inventory turnover, and receivables turnover on the profitability of pharmaceutical companies listed on the Indonesia Stock Exchange (IDX) for the period 2019-2022. This quantitative explanatory research uses secondary data from the financial reports of pharmaceutical companies listed on the IDX. Data analysis techniques include classical assumption tests and panel data regression to examine the relationship between the independent variables (cash turnover, inventory turnover, and receivables turnover) and the dependent variable (profitability). The results indicate that all three variables, both partially and simultaneously, have a significant effect on profitability. Efficient management of cash, inventory, and receivables contributes to higher profitability levels. This study highlights the importance of effective management of these components in improving the financial performance of companies. Limitations of the study include reliance on secondary data and a population limited to pharmaceutical companies listed on the IDX. Future research is suggested to extend the study period and consider other variables such as cost management and investment. A mixed-method approach with qualitative insights can provide deeper understanding. This study offers significant contributions to understanding how the management of cash, inventory, and receivables affects the profitability of pharmaceutical companies in Indonesia, and provides practical recommendations for companies, investors, and regulators to enhance the financial performance of the pharmaceutical sector.