<p style="text-align: justify;"><strong>Abstract. </strong>Quality of life (QoL) is a concept which aims to capture the well-being, whether of a population or individual, regarding both positive and negative elements within the entirety of their existence at a specific point in time. Many studies have found that PTSD symptoms can worsen the quality of life of COVID-19 survivors, and a high level of resilience can indicate a good quality of life for COVID-19, because a high level of resilience makes people able to rise from their worst condition. This study aimed to explain the mediating effect of resilience on the relationship between PTSD symptoms and the COVID-19 survivors’ quality of life. This study used a quantitative method, and 133 participants (mean age: 26.738; 75.2% female) were selected using a convenience sampling technique. Data analysis in this study used the IBM SPSS Statistics 26.0 program. PROCESS Macro 4.1 add-on by Hayes. Research results showed that in path a, PTSD symptoms significantly predicted resilience (? = -0.049; p = 0.001; LLCI = -0.072; ULCI = -0.020). In path b, resilience also significantly predicts quality of life (? = 2.156; p = 0.000; LLCI = 1.443; ULCI = 2.868). The direct effect of PTSD symptoms on quality of life shown in path c' is also significant (? = -0.387; p = 0.000; LLCI = -0.511; ULCI = -0.263) which gives higher results than the total effect (? = -0.493; p = 0.000; LLCI = -0.626; ULCI = -0.359). The results of the study show that PTSD symptoms had an antagonistic relationship, and resilience had a positive relationship with COVID-19 survivors’ quality of life. In addition, resilience was also found to significantly mediate the relationship between PTSD symptoms and COVID-19 survivors’ quality of life. COVID-19 survivors are advised to increase their resilience level to reduce the negative impact of PTSD symptoms on their quality of life.</p><p style="text-align: justify;"><strong><em>Keywords: </em></strong><em>COVID-19 survivors; PTSD symptoms;  quality of  life; resilience</em></p>

<p><strong>Abstract</strong><strong>.</strong> Stroke will experience setbacks such as difficulty in thinking, speaking and moving. This condition creates a feeling of helplessness with his life, so that post-stroke patients are prone to depression. The purpose of this study was to determine the effect of giving Acceptance and Commitment Therapy (ACT) in reducing depression in post-stroke patients. This study involved 6 post-stroke participants with major depression. The research method used was quantitative- true eksperiment. Based on the results of the Mann-Whitney posttest, there was a significant difference in scores between the groups that were given Acceptance and Commitment Therapy (ACT) and those who were not given Acceptance and Commitment Therapy (ACT) (0.023; p &lt;0.05). So it can be concluded that Acceptance and Commitment Therapy (ACT) can be used to reduce depression in post-stroke patients.<br /><strong><em>Keyword</em></strong><strong><em>s:</em></strong><em> </em><em>Depression, Acceptance and Commitment Therapy (ACT), post-stroke.</em></p><p><strong>Abstrak</strong><strong>. </strong><em>Stroke </em>akan menyebabkan seseorang mengalami kemunduran seperti kesulitan dalam berpikir, berbicara dan bergerak. Kondisi ini menimbulkan perasaan tidak berdaya dengan hidupnya, sehingga pasien <em>pasca-stroke</em> rentan terhadap depresi. Tujuan penelitian ini adalah untuk menguji pengaruh <em>Acceptance and Commitment Therapy</em> (ACT) dalam menurunkan depresi pada pasien <em>pasca-stroke</em>. Penelitian ini melibatkan 6 partisipan <em>pasca-stroke</em> dengan depresi berat. Metode penelitian yang digunakan adalah kuantitatif-<em>true </em>eksperimen. Berdasarkan hasil <em>posttest </em>uji <em>Mann-Whitney</em> menunjukkan adanya perbedaan skor depresi yang signifikan antara kelompok yang diberikan <em>Acceptance and Commitment Therapy</em> (ACT) dan kelompok yang tidak diberikan <em>Acceptance and Commitment Therapy</em> (ACT) (0,023; p&lt;0,05). Maka dapat disimpulkan bahwa <em>Acceptance and Commitment Therapy</em> (ACT) efektif digunakan untuk menurunkan depresi pada pasien <em>pasca-stroke</em>.<br /><strong><em>Kata kunci:</em> </strong><em>Depresi, Acceptance and Commitment Therapy (ACT), pasca-stroke.</em></p>