This study aims to determine the feasibility and impact of virtual laboratories in learning the material of innovation in biological technology (biotechnology) for high school students in grade X. The feasibility assessment was carried out by three expert validators using a questionnaire instrument that measured aspects of material, media, and language and based on readability tests by teachers and students. The results of the study showed that the percentage of validity of the Virtual Laboratory from material experts was 95%, media experts 83%, language experts 90% with the third category being "Very Feasible". The results of the readability test from teachers obtained a percentage of 96% while the results of the readability test from students obtained a percentage of 99%. These results indicate that the Virtual Laboratory is Feasible and Practical to be used for biology learning, especially biotechnology material. The results of the teacher response test on the use of Virtual Laboratory showed a percentage of 95% while the results of the student response test were 75%. The results of the T test showed that Virtual Laboratory had a significant effect on students' conceptual understanding with a significance of 0.001. These results indicate that Virtual Laboratory is effective in improving students' conceptual understanding, especially in biotechnology material.

Diabetes Mellitus merupakan suatu penyakit menahun atau kronis yang ditandai oleh hiperglikemiaatau kadar glukosa darah melebihi nilai normal. Pengobatan non farmakologi diabetes mellitus dapat menggunakan tanaman herbal, seperti kulit manggis. Data yang di peroleh dari Puskesmas Joho terdapat 12 responden yang memiliki riwayat diabetes mellitus di desa Joho Baru, Joho, Sukoharjo. Tujuan penelitian ini untuk mengetahui pengaruh kulit buah manggis terhadap penurunan kadar gula darah pada penderita diabetes mellitus. Metode penelitian menggunakan pretest-posttest Design. Teknik penggambilan sampel Accidental Sampling, sejumlah 12 responden. Uji normalitas yang dilakukan adalah uji shapiro-walk dan teknik analisa menggunakan Wilcoxon test.
dengan hasil didapatkan ada pengaruh kulit manggis terhadap penurunan kadar gula darah yang signifikan (p) 0.002 karena nilai p (<0.05) ), maka hipotesis alternatif (Ha) diterima, yang artinya dimana ada pengaruh kadar gula darah sebelum dan sesudah diberikan kulit manggis