Shina, mai., 2024, test of antibacterial activity of extract, water fraction, ethyl acetate fraction, and n-hexane fraction of chinese petai leaf (leuncaena leucocephala) against staphylococcus aureus atcc 25923, thesis, faculty of health sciences, duta bangsa university, surakarta one of the traditional medicines that currently has the potential to be developed is the chinese petai plant (leucaena leucocephala). Chinese petai leaves are used by the people of indonesia as a remedy for new and swollen wounds. Staphylococcus aureus is a gram-positive coccus bacterium that is the main pathogen in humans. Almost everyone has experienced a wide variety of staphylococcus aureus infections during their lifetime, from severe food poisoning to minor skin infections. The methods used in this study are diffusion and dilution. The purpose of this study was to determine the antibacterial activity of water extracts and fractions, ethyl acetate fractions, and n-hexane fractions of chinese petai leaves (leuncaena leucocephala), to find the most active extracts and fractions based on their inhibitory zones, and to determine the khm and kbm of the most active extracts against staphylococcus aureus atcc 25923. Based on research conducted on ethanol extract, water fraction, ethyl acetate fraction, and n-hexane fraction of chinese petai leaves have antibacterial activity against staphylococcus aureus atcc 25923. The most active extract in inhibiting staphylococcus aures atcc 25923 judging from its inhibition zone value is ethanol extract. Ethanol extract of chinese petai leaves has the same khm and kbm values, namely at a concentration of 25%.
 
 
 

Drug management is a cycle including selection, procurement, distribution and use which is supported by an appropriate organizational structure, finances and management information system. The aim of this research is to determine drug management in the Pharmacy Installation at RSUD dr. Soeratno Gemolong, Sragen Regency.This research uses prospective and retrospective methods. Where retrospective data is taken from 2022 data. Prospective data is taken through direct observation. The results of this research are: the percentage of available funds and the required funds is 80%, the percentage of procurement and actual use is 98%, invoice errors are 0.47%, there are no delayed payments by hospitals, compatibility between drugs and stock cards is 100% , drug availability level of 16 months, warehouse management system with FIFO, FEFO and LASA marking systems, average time used to serve compounded prescriptions is 11 minutes and non-mixed prescriptions is 7 minutes, conformity of drug items with the National Formulary is 93%, frequency of procurement of each drug item 4-6x a year, turn over ratio 3 times, percentage of expired and damaged drug value 5.05%, dead stock percentage 3%, number of drug items per prescription sheet 3.5 items, percentage of prescriptions with generic names 88%. These results indicate that drug management in the Pharmacy Installation at RSUD dr. Soeratno Gemolong, Sragen Regency is not yet good.