This research aims to examine the influence of creativity, motivation and family environment on the entrepreneurial interest of Karang Taruna members in Dukuh Bancakan, Wonorejo, Polokarto, Sukoharjo. Using a saturated sampling technique, this research involved 79 members as respondents. Data was collected through a questionnaire which included the variables creativity, motivation, family environment and entrepreneurial interest, and analyzed using multiple linear regression. The findings show that motivation has a significant positive influence on entrepreneurial interest, while creativity and family environment do not show a significant influence. These results indicate that motivation is a key factor in encouraging entrepreneurial interest among Karang Taruna members. Therefore, entrepreneurship programs should focus more on developing motivation to increase youth participation in entrepreneurship.