<p>This study explores the interplay among employee engagement, perceived organizational support, and employee retention within the pharmaceutical industry. Data analysis from professionals in this sector revealed that employee engagement was a significant mediator, accounting for 33.8% of the variance in employee retention. The research underscores the pivotal role of employee engagement in shaping organizational support and retention outcomes specific to pharmaceutical companies. Prioritizing initiatives to boost employee engagement is crucial for fostering a dedicated workforce and improving organizational performance in pharmaceutical companies. These findings contribute valuable insights to enhance human resource management strategies tailored to the pharmaceutical industry, emphasizing the strategic significance of investing in employee engagement to ensure sustainable organizational success.</p>