This study aims to analyse the relationship between the level of health knowledge and the use of herbal therapy in hypertensive patients in Aldehia (One-Sere, Casmuto, Suli-Ua), Suco Buruma, Posto Administrativo Baucau, Municipiu Baucau, Timor Leste in 2024.  This study used a quantitative design with a cross-sectional approach. The study population consisted of hypertensive patients in Aldehia (One-Sere, Casmuto, Suli-Ua), Suco Buruma, Posto Administrativo Baucau, Municipiu Baucau, Timor Leste in 2024. The sample was selected by random sampling. Data were collected through a structured questionnaire with variables of health knowledge, use of herbal therapy, and other factors that influence the decision to use herbal therapy.65% of hypertensive patients have a low level of health knowledge and 67.5% do not use herbal therapy. There was a significant relationship between the level of health knowledge and the use of herbal therapy. Statistical tests showed that a better level of health knowledge tended to be associated with increased use of herbal therapy, with a significant p-value (p = 0.000), which suggests that health knowledge influences patients' decision to adopt herbal therapy. Education level was significantly associated with herbal therapy use (p = 0.015), where higher education level increased the likelihood of herbal therapy use (Exp(B) = 2.034). This study shows the importance of improving health knowledge and education in influencing the use of herbal therapy among hypertensive patients.