Purpose: The cardiovascular system is a vital system responsible for the distribution of oxygen and nutrients throughout the body. The complexity of interactions between the heart and blood vessels often presents challenges in monitoring and analyzing health conditions. The research proposes the development of a Human Digital Twin (HDT) for the cardiovascular system through application of two different modelling approaches geometric modeling and physic-based modeling. Through this model physical conditions can be represented and real time data integrated to offer insights into the dynamics of the cardiovascular system.
Methods: This model development is based on two major components: a geometric modeling and a physic-based modeling. The geometric model is done in 3D to show the structure of the heart in detail, while the physical-based model is tabulated with different measurable physical parameters in the cardiovascular system, such as blood pressure and flow rate. This information is integrated into the Five Dimension Digital Twin model, including physical, virtual, data, connection, and service dimensions for the accurate simulation of cardiovascular conditions.
Result: Results confirm that the Five-Dimensional Digital Twin (DT) could give further development to how the dynamics of the cardiovascular system behave, possibly in real-time updates on conditions and a supply of data that is far more detailed in view of analyzing risk and further representation of specific cardiovascular disorders while providing personalized medical support.
Novelty: The Five-Dimensional Human Digital Twin Model (HDTM) developed in this research introduces novel innovations in the monitoring and simulation of the cardiovascular system through the application of geometric and physic-based modeling techniques. This approach offers a higher level of detail, compared to previous models, and added value for the advancement of health technology by integrating real time data into the simulations. This model serves not only as an advanced analytical tool but also as a reference for further research on DT technology in the medical field.

This article discusses the phenomenon of healing beliefs in Javanese and Japanese culture which is presented through the narrative of the novel Pingkan Melipat Distance by Sapardi Djoko Damono. The novel explores the complexities of cross-cultural relationships, highlighting the traditional beliefs that influence the way the main character, Pingkan, deals with emotional and identity crises. In Javanese culture, healing beliefs are rooted in harmony between spirituality, nature and the body, while in Japanese culture, balance between the body, mind and environment is the main foundation. This article finds that through Pingkan's journey, this novel represents a cross-cultural dialogue that not only connects local and global values ??but also opens up space for reflection on identity and healing in the modern era. With a literary approach and cultural perspective, this article presents an in-depth understanding of how healing traditions contribute to the sustainability of cultural values as well as being a tool to face the challenges of globalization.

This study aims to evaluate the impact of Work-Life Balance, Employee Internal Marketing, and Corporate Culture on Organizational Citizenship Behavior (OCB) among employees of PT XYZ Cikarang. OCB is a voluntary action taken by employees to improve organizational performance beyond their official responsibilities. An optimal work-life balance can improve employee well-being and strengthen their commitment to the company. Internal Employee Branding serves to strengthen employees' identity and relationship with the company, while Corporate Culture forms values and norms that encourage constructive behavior in the work environment. This study applies a quantitative method with a multiple regression analysis approach. Information was obtained through questionnaires distributed to employees of PT XYZ Cikarang. The research findings indicate that work-life balance, internal marketing for employees, and organizational culture have a positive and significant impact on OCB, both separately and together. The main factor that is most influential in strengthening OCB is Organizational Culture, which shows the important role of company values and norms in shaping employee attitudes. The findings suggest that companies should improve work-life balance, strengthen internal brands, and create a supportive organizational culture to encourage employees to perform behaviors that go beyond their responsibilities.

This research aims to test and analyze the influence of Leadership Style and Organizational Culture on employee performance at the Pondok Cabe Open University Head Office.This research design is quantitative with an associative type. This research uses primary data. The population used was 81 employees of the Pondok Cabe Open University Head Office. This research method used is a quantitative method that is associative with a sampling technique, namely a saturated sample. The data analysis technique used was multiple linear analysis using SPSS version 2.0.The results of this research show that leadership style has a positive and significant effect on employee performance at Pondok Cabe Open University. Organizational culture has a positive and significant effect on employee performance at Pondok Cabe Open University. Leadership Style and Organizational Culture have a positive relationship and have a significant effect on Employee Performance at Pondok Cabe Open University.