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Local food innovation is not only focused on product development but also requires effective communication strategies to build positive perceptions and enhance market competitiveness. This study aims to analyze the implementation of innovation communication strategies by micro, small, and medium enterprises (MSMEs) in developing papaya-based chili chips as a flagship product in Nagori Karang Anyar, Gunung Maligas District, Simalungun Regency. The research employs a descriptive qualitative approach, focusing on the product innovation process, marketing communication patterns, and efforts to build product image amid competition in the local food industry. The findings indicate that innovation communication strategies play a crucial role in creating product differentiation through narratives of unique taste, utilization of local raw materials, and promotional strategies combining traditional methods and digital media. Papaya chili chips are positioned as a product that blends distinctive local flavors with a modern touch, attracting consumer interest and increasing the added value of papaya as a local commodity. This study emphasizes that the success of local food innovation depends not only on product quality but also on the ability of MSMEs to manage adaptive and persuasive communication strategies.

A high-fat diet can cause hyperlipidemia, which is one of the main risk factors for atherosclerosis. Papaya flowers (Carica papaya L.) contain antioxidants that have the potential to inhibit the development of atherosclerotic lesions. This study aims to determine the effect of papaya flower extract on the histopathological features of the aorta of Wistar rats induced by a high-fat diet. The study design is a posttest only-trial group design. The study sample consisted of 25 male Wistar rats divided into 5 groups with treatment for 21 days. Group A received no treatment. Group B was given high-fat diet consisting of 3 mL of pork fat and 2 g of duck egg yolk. Group C was given high-fat diet and simvastatin 0.18 mg/200 gBW. Groups D and E were given high-fat diet and papaya flower extract 125 mg/kgBW and 250 mg/kgBW, respectively. The parameter used is the histopathological description of the aorta in the form of foam cell formation. The results showed that there were few foam cell in group A. Group B had many foam cells in the tunica intima and media of aorta. Group C, D and E showed a reduction in the number of foam cells. The administration of papaya flower extract (Carica papaya L.) was effective in inhibiting foam cell formation in the aorta of Wistar rats induced by a high-fat diet, with a better effect seen at a dose of 250 mg/kgBW, which was almost comparable to simvastatin.

The extract of Carica papaya L. leaves contains phytochemical compounds such as flavonoids, alkaloids, phenolics, and saponins that play a role in biological activities, including antioxidants, anti-inflammatory, analgesic, and modulation of the nervous system. This study aims to evaluate the effects of fresh papaya leaf extract on the central nervous system (CNS) and autonomic nervous system based on varying extract concentrations. The study used test animals with treatment groups consisting of negative control, positive control, and extracts at concentrations of 4%, 8%, and 16%. Parameters observed included parasympathomimetic (PSM), parasympatholytic (PSL), sympathomimetic (SM), sympatholytic (SL), analeptic effects (ANA), CNS stimulation (SSSP), CNS depression (DSSP), and muscle relaxation (RO). The results showed that the 16% concentration produced the highest PSM activity (46.82%) and dominant CNS stimulation (38.59%), while DSSP and RO decreased at higher concentrations. This phenomenon indicates that increasing the extract concentration does not always enhance CNS depression, but rather leads to stimulation. These findings support the potential of papaya leaf extract as a neuroprotective and multifunctional agent. Further research is needed to confirm its molecular mechanisms and clinical effectiveness as a phytotherapy candidate.

This Community Service Program (PKM) was implemented in Siantar Martoba, Pematangsiantar City, with the aim of enhancing the local economy through empowering farmer groups in optimizing backyard land. The program is a collaboration between Universitas Murni Teguh PSDKU Pematangsiantar, Politeknik Bisnis Indonesia, and the Food Security and Agriculture Office of Pematangsiantar City, attended by 15 farmers on July 4, 2025. The resource person, Henry Dunan Pardede, S.P., M.M., provided training on cultivating high-value crops such as California Papaya and Caplak Chili. The activities consisted of preparation, training, field assistance, and distribution of seedlings. The results showed an improvement in skills, entrepreneurial motivation, and more productive use of backyard land. This program also contributed to the achievement of SDGs point 1 (No Poverty), point 2 (Zero Hunger), and point 8 (Decent Work and Economic Growth) by strengthening the local economy based on agricultural potential. With a community-based approach, this program successfully increased food security, household income, and the sustainability of agricultural practices, while demonstrating the effectiveness of empowerment that can be extended to other areas facing similar challenges.

This community service article presents the implementation of the GELORA outreach and training program conducted in Sebanen Village, Jember, Indonesia, focusing on the promotion of low-cost and eco-friendly fermented feeds formulated from locally available agricultural residues such as papaya leaves, rice bran, molasses, and EM4. The program aimed to strengthen the capacity of smallholder catfish farmers and the village enterprise (BUMDes) through a series of integrated activities including a rapid needs assessment, hands-on training sessions, technical mentoring, and knowledge dissemination. As a result, participants demonstrated improved technical skills in household-scale feed formulation and fermentation, a stronger understanding of sustainable and circular economy principles, and an increased willingness to adopt environmentally friendly aquaculture practices. Moreover, follow-up mentoring groups were established to ensure program continuity and local innovation. This participatory model effectively combines community engagement with scientific evidence in aquaculture nutrition and is suitable for replication in other rural aquaculture development contexts.

Globally, 33% of all productive women aged 15-49 have anemia problems. Anemia is a condition where there is a deficit of erythrocyte cells, which is often found in all age groups, including women of childbearing age (WUS) and young women, namely 29% of young women and non-pregnant women and 38% of pregnant women have problems with anemia. This research aims to determine the effect of giving papaya fruit to young women who suffer from anemia on increasing hemoglobin in the work area of the Jabi Village Community Health Center, Batam City in 2024. This research was conducted using the Pre-Experiment method using the One Group Pretest Posttest Design approach. The sample for this research was 16 young women. The results of this study showed that the majority of young women experienced moderate anemia, as many as 10 young women (62.5%). After giving papaya to young women for 10 days, it was found that the majority of young women were not anemic, as many as 10 young women (62.5%). Based on the results of the Paired Sample T Test statistical test, show that the p-value is 0.000 < 0.05, so it can be concluded that there is an effect of giving papaya fruit to young women who experience anemia on increasing hemoglobin in the working area of the Jabi Village Community Health Center, Batam City in 2024. It is hoped that the Health workforce can minimize anemia in young women by giving them papaya.

The agricultural sector plays a strategic role in ensuring national food security, particularly in rural areas where the majority of the population depends on agricultural production. Sememu Village, an agricultural-based community with rice and tobacco as its primary commodities, has faced recurring pest attacks in recent years. Conventional pest control methods in the area have primarily relied on chemical pesticides. However, excessive and prolonged use of these chemicals has resulted in serious problems, including pest resistance, environmental contamination, and potential health risks to farmers and consumers. This study aims to improve farmers’ knowledge and practical skills by introducing an alternative, eco-friendly approach through a training program on the production of botanical pesticides derived from papaya leaves (Carica papaya L.). Papaya leaves are known to contain bioactive compounds such as papain, chymopapain, alkaloids, terpenoids, and flavonoids, which exhibit natural insecticidal properties. The training activities consisted of initial observation, presentation of scientific and practical materials, hands-on practice in the preparation of botanical pesticides, and field testing on rice and tobacco plants. The findings demonstrated that the use of papaya leaf-based pesticides effectively reduced pest feeding activity and increased pest mortality rates, thereby minimizing crop damage. Importantly, this approach did not cause harmful effects on the surrounding ecosystem. The program highlights the potential of botanical pesticides as a sustainable solution for integrated pest management in agricultural villages, contributing both to environmental conservation and farmers’ welfare.

The agricultural sector plays a vital role in supporting Indonesia's economy, particularly in food provision and increasing rural household income. One of the promising horticultural commodities is California papaya (Carica papaya L.), known for its high productivity and short harvesting cycle. This crop is favored by farmers due to its stable market demand. However, to ensure the financial feasibility of this farming enterprise, a comprehensive financial analysis is necessary. This study aims to analyze the revenue, production costs, income, and financial feasibility of California papaya farming in Hinai Subdistrict, Langkat Regency. The research employed a descriptive quantitative method through a survey approach, with a purposive sample of 34 farmers. Data were analyzed using a farm income analysis approach, including the calculation of fixed costs, variable costs, total revenue, net income, and the Revenue/Cost (R/C) ratio. The results showed that the total production cost was IDR 590.734.000, while the total revenue reached IDR 1.970.685.000. The net income obtained by farmers amounted to IDR 1.379.951.000, with an average income of IDR 40.586.794 per farmer. The R/C ratio was calculated at 3.33, meaning that every IDR 1 spent on production costs generated IDR 3.33  in revenue. California papaya farming in Hinai Subdistrict is financially feasible, provides significant profit, and has strong potential to be further developed as a primary income source for horticultural farmers.

This study aims to describe the level of consumer liking or acceptance of a product, it absolutely requires a test called the organoleptic test and hedonic test This research was conducted in quantitative analysis In the implementation of this study, the experiment conducted was an experiment consisting of 4 treatments, Each treatment was carried out as many as 3 replicates so that 12 experimental units were obtained The treatments used were po (control) = regular sauce 100% Traditional chilli sauce packaging, p1 = 50% papaya sauce and 50% carrot sauce 500 grams of papaya + 500 grams of carrots, p2 papaya sauce (pure) 100% 1 kg papaya, p3 = carrot sauce (pure) 100% 1 kg organoleptic research results The highest colour was p1 4.3, aroma p3 3.9, taste p1 3.95, and texture p14. 25. As for hedonics, the highest was for colour p1 4.75, aroma p3 4.55, taste p1 4.25 and texture p3 4.5. Organoleptic tests involving colour, aroma, taste and texture showed values for colour in sample 1 with an average value of 4.3, aroma in sample 3 with an average value of 3.9, taste in sample 1 with an average value of 3.95 while texture in sample 1 with an average value of 4.25. The results of the hedonic test assessed consumer preference for sauces in samples 1 and 3 for sample I with an average value of 4.75 and a taste of 4.25 in the like category. While in sample 3 consumer assessment of aroma average value 4.55 and texture 4.5 category.

Abstrak. Osteoporosis is a degenerative bone disease characterized by a decrease in bone mass and strength, particularly in postmenopausal women. Traditional plant-based therapy presents an attractive alternative given the rich local bioactive potential and limited access to pharmacological treatments. One important biochemical indicator in bone regeneration is the level of alkaline phosphatase (ALP). The aim of this study is to evaluate the potential of various Indonesian traditional medicinal plants as bioactive agents in the prevention of osteoporosis, with an emphasis on increasing ALP levels. This method employed a literature search by collecting several scientific articles discussing the anti-osteoporosis activity of traditional medicinal plants through in vitro, in vivo, and clinical observation studies. The results obtained show that traditional medicinal plants such as Turmeric (Curcuma longa), Black pepper (Piper nigrum), Bromelain (Ananas comosus), Papaya (Carica papaya), Japanese knotweed (Reynoutria japonica Houtt.), Veratrum nigrum, Sickle senna (Cassia tora), Red ginger (Zingiber officinale var. rubrum), Clove (Syzygium aromaticum L.), White turmeric (Curcuma zeadoaria), and Celery (Apium graveolens) are capable of reducing the number of osteoclasts and promoting bone formation. These findings consistently demonstrate a positive role in bone health through increased ALP levels. Indonesian traditional medicinal plants hold great potential as evidence-based anti-osteoporosis agents, particularly through enhancing ALP levels and osteoblast activity. This literature review supports the development of local herbal therapy as a promotive and preventive alternative against osteoporosis.

Malaria remains a significant public health issue in Indonesia, particularly in endemic areas such as Keerom Regency, Papua. Efforts to control this disease face challenges due to Plasmodium resistance to synthetic drugs, highlighting the need for safer and more effective alternative treatments. This study aims to identify the secondary metabolite content of several local plants traditionally used as antimalarial remedies. An experimental laboratory study was conducted using phytochemical screening methods. The plants examined included turmeric rhizome (Curcuma longa), meniran leaves (Phyllanthus niruri), papaya leaves (Carica papaya), sambiloto (Andrographis paniculata), and brotowali (Tinospora crispa). Extraction was carried out using the maceration method with 96% ethanol as the solvent. The results showed that all samples contained secondary metabolites such as flavonoids, alkaloids, tannins, and saponins, which are known for their antiplasmodial activity. Extract yields ranged from 18% to 24%, with turmeric rhizome showing the highest yield. These findings suggest that local plants from Keerom Regency hold potential as raw materials for the development of herbal antimalarial drugs. This study serves as a preliminary step for further in vitro and in vivo bioactivity testing.

Indonesia has around 3,500 species of therapeutic plants, one of which is utilized by the individuals of Selilau Town, Aru Islands Rule, Maluku Area.. This study aims to examine 15 types of medicinal plants that are used traditionally, including plant parts, properties, active compound content, and pharmacological activity based on scientific literature from the last 10 years. This survey points to recognize species of restorative plants commonly utilized in neighborhood conventional medication, look at the plant parts utilized, handling strategies, and maladies treated based on neighborhood experiences and to survey logical writing to decide the dynamic compound substance and pharmacological movement of each distinguished plant. The comes about of the think about appeared that the foremost broadly utilized plant is the leaf portion. Some of them are: Momordica charantia (bitter melon) for cough; Urena lobata (pulutan) to smooth postpartum blood; Morinda citrifolia (mengkudu) for broken bones; Erythrina variegata (dadap) for body recovery; Myrmecodia pendens (ant nest) for swelling and beriberi; and Carica papaya (papaya) for malaria. Other plants such as Manihot esculenta, Tradescantia spathacea, Graptophyllum pictum, Hemigraphis alternata, Mimosa pudica, Jatropha curcas, Psidium guajava, Nypa fruticans, and Stachytarpheta jamaicensis are also used for various health complaints. Active compounds such as flavonoids, alkaloids, tannins, and saponins support pharmacological activities such as anti-inflammatory, antioxidant, antipyretic, gastroprotective, and immunostimulant. This study emphasizes the importance of documenting traditional knowledge as an effort to preserve and develop local wisdom-based medicines.

This study aims to analyze the level of attack by Macaca hecki on cultivated plants in Makarti Jaya Village, Pohuwato, Gorontalo. Agriculture is the main source of income for the local community, but the presence of Macaca hecki can threaten agricultural yields. The method used in this research is descriptive qualitative, with data collected through direct observation and interviews with farmers experiencing the attacks. The results indicate that corn (Zea mays) is the most consumed plant by Macaca hecki, followed by cocoa (Theobroma cacao) and several other types of fruit such as bananas and papayas. The high consumption rates of these cultivated plants negatively impact agricultural results, causing significant economic losses for farmers. Therefore, it is important to understand the attack patterns and the factors influencing the behavior of Macaca hecki. This research recommends the need for more effective protection strategies, such as the placement of physical barriers and diversification of plant types. Thus, it is hoped that this study can contribute to the management of conflicts between wildlife and agriculture, as well as enhance the economic sustainability of farming communities.

Breast milk (BM) is the optimal source of nutrition for newborns up to six months old, providing essential antibodies, complete nutrition, and easier digestion compared to formula milk. Exclusive breastfeeding is crucial for infant health, and efforts to support lactation include consuming a balanced and nutritious diet. This study aimed to examine the effect of papaya and watermelon consumption on breast milk expression in nursing mothers. The research utilized a true experimental design with a two-group post-test approach, conducted over five consecutive days. The intervention involved consuming 400 grams of cut papaya and 300 grams of watermelon daily. The study population consisted of postpartum mothers with infants aged 0–6 months, and the sampling technique used was probability sampling, resulting in a total of 42 respondents. Participants were divided into two groups: 21 in the control group and 21 in the intervention group. The Wilcoxon test was applied for statistical analysis. The findings revealed that papaya consumption significantly affected breast milk expression, with a p-value of 0.046 (<0.05), accepting the alternative hypothesis (Ha). This result indicated that papaya intervention increased breast milk expression by 2,000 times. Similarly, the watermelon intervention showed a significant effect, with a p-value of 0.02 (<0.05), also leading to the acceptance of the alternative hypothesis (Ha). The analysis suggested that watermelon consumption improved breast milk expression in nursing mothers by 3.162 times. These findings highlight the potential benefits of consuming papaya and watermelon in enhancing lactation, providing valuable insights for nursing mothers and healthcare professionals in supporting breastfeeding practices.

This study aims to develop a natural-based herbal shampoo using Ceiba pentandra (L.) Gaertn leaves and Carica papaya L. seeds as a safer and eco-friendly alternative to synthetic shampoos, which often contain harmful chemicals. Ceiba pentandra leaves contain active compounds such as flavonoids, alkaloids, and saponins with antibacterial properties, while Carica papaya seeds contain glucoside circirindan, which is beneficial for treating gray hair. The research method involves the use of influence diagrams and mathematical models to determine the most effective ingredient formulation. The experimental results showed that the best composition consists of 60 grams of Ceiba pentandra leaves, 30 grams of Carica papaya seeds, 5 grams of texavon, 10 grams of NaCl, and 350 ml of distilled water. The resulting herbal shampoo product is not only effective and economical but also environmentally friendly.

Virgin Coconut Oil (VCO) is derived from fresh coconut meat and can be produced through various methods, including enzymatic processes. This study investigates the effect of adding papain enzyme on the antioxidant activity of VCO. The enzymatic method involves extracting coconut milk with the addition of papain obtained from young papaya. The antioxidant activity was measured using the DPPH method, while other parameters such as moisture content and free fatty acids were also evaluated.The research highlights that VCO is recognized for its health benefits and versatility in various applications. The enzymatic extraction method offers an efficient means of producing VCO while enhancing its properties. This study specifically focuses on how the incorporation of papain influences both the quality of VCO and its antioxidant capacity.In terms of methodology, the study utilized an enzymatic approach for VCO production by incorporating papain into the extraction process. The antioxidant activity was assessed using the DPPH assay, and the resulting VCO was analyzed for moisture content and free fatty acids.The results indicated that VCO produced with papain had a moisture content of 0.22% and free fatty acids of 0.76%, while VCO without enzyme addition showed a moisture content of 0.16%. The antioxidant activity was measured at 18.35 ppm for VCO with papain, compared to 13.51 ppm for pure VCO.In conclusion, the addition of papain enzyme not only accelerated the production of VCO but also enhanced its antioxidant activity, classifying both types of VCO as having strong antioxidant properties. However, it is important to note that the moisture content and free fatty acids in VCO with enzyme addition did not meet the Indonesian National Standard (SNI 7381:2008), likely due to residual water from the papaya fruit.

This study evaluated the impact of papaya leaf (Carica papaya L.) supplementation in bran feed on body weight and body size of chickens (Gallus domesticus). Three groups of chickens were fed with papaya leaf flour supplementation to see the efficiency on chicken growth. This study was conducted for 28 days at the "Rinael Farm" Farm, Pulerejo Village, Manggis, Mojosongo, Boyolali, Central Java. This study was implemented through an experimental method with a Completely Randomized Design (CRD) design that included three treatments and three repetitions: P0 (no supplementation), P1 (10% supplementation), and P2 (20% supplementation). The results of the study proved that 10% and 20% papaya leaf supplementation did not have a significant effect on chicken weight (P> 0.05). However, papaya leaf supplementation had a significant impact on the characteristics of chicken body size, with a p value <0.001. Papaya leaf supplementation increased chicken body size, with group P1 experiencing the most significant and consistent increase, while group P2 showed greater variation in growth. Supplementation with 10% papaya leaves (P1) proved to be the most effective in increasing chicken growth efficiency.

World Health Organization (WHO) 41% of pregnant women worldwide experience anemia. Overall, the prevalence of anemia in pregnant women in developed countries is 49% and in developing countries it is 53%. In Indonesia, the rate of anemia in pregnant women is quite high, namely 48.9%. Anemia that is commonly experienced by pregnant women is iron deficiency anemia. Iron is needed in hemopoesis (blood formation), namely in the synthesis of hemoglobin. Iron absorption can be increased by consuming ± 25 mg of vitamin C sources in food. The aim of the research was to determine the difference in the effectiveness of papaya and red guava on hemoglobin levels in pregnant women with anemia. The research was conducted at the Nagaswidak Community Health Center in June 2024 using a quasi-experimental two group pretest and posttest. The population in this study were all pregnant women who were in the working area of the Nagaswidak Palembang Community Health Center in May 2024 with Hb levels of 9 – 10.9 gr/dl. The sampling technique used purposive sampling totaling 30 respondents. The results of the Wilcoxon test research showed that the effect of papaya (p value 0.000) and guava (p value 0.000) was obtained. The results of the Mann Whitney union obtained a p value of 0.116. There is an effect of papaya on hemoglobin levels in pregnant women, there is an effect of guava on hemoglobin levels. There is no difference in the effect of papaya and guava on hemoglobin levels in pregnant women at the Nagaswidak Community Health Center. It is hoped that health workers will increase education regarding the prevention of anemia in pregnant women, one of which is by consuming vitamin C in fruit.

Medicinal plants are plants whose leaves, stems and roots can be used as medicine. Some of these medicinal plants are used in traditional or alternative medicine in local communities. Apart from that, medicinal plants also have the advantage that they do not cause side effects and can be treated by family members themselves. The successful use of medicinal plants is greatly influenced by public knowledge about the benefits of each type of medicinal plant, especially medicinal plants that have been studied empirically. Research with the title Inventory of Medicinal Plants in the Babakan Siliawangi City Forest Area on June 12 2024, with this research method aims to determine the diversity of types of medicinal plants and to determine the potential of these medicinal plants for the surrounding community. The results of this research were 10 types of medicinal plants, including: Binahong, Yellow Bamboo, Jengkol, Matoa, Forest Tea, Forest Betel, Japanese Papaya, Sausage Tree, Butterfly Tree, Simpur Tree. The most widely used medicinal plant organ is the root, bark, flowers and leaves.    

This research discusses the implementation and evaluation of the Convolutional Neural Network (CNN) convolutional neural network model for classification of fruit types, specifically to differentiate between Banana and Papaya. The CNN model used consists of several convolutional, pooling, and fully connected (dense) layers designed to extract features and perform binary classification. Data augmentation is applied to the training set to increase data variation and prevent overfitting. The image data used is normalized to speed up training convergence. The model was trained using the Adam optimizer and the binary crossentropy loss function for 20 epochs. Performance evaluation was carried out using the validation set. The results show that the model is able to effectively classify fruit images with a high level of accuracy. Predictions are made by uploading images, resizing them, and normalizing them before using the model for predictions. The classification threshold was set at 0.4, where a predicted probability greater than or equal to 0.4 was classified as Banana and a probability less than 0.4 was classified as Papaya. This research shows that the CNN model can be used effectively for binary image classification tasks and can be extended to classify more types of fruit with appropriate data adjustments and model architecture.