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This study aims to analyze the trends in the prevalence of ischemic heart disease (IHD) in Indonesia from 2019 to 2023 based on data from the Global Burden of Disease (GBD) study, with a focus on gender differences between males and females. The data used in this study includes detailed prevalence data for IHD based on province and gender. The analysis reveals that the prevalence of IHD is higher in males than in females, with greater fluctuations observed in females, particularly after menopause. Although there are significant differences in the prevalence across several provinces, risk factors such as smoking, obesity, hypertension, and diabetes contribute significantly to the increasing prevalence of this disease. However, the differences in prevalence between provinces and genders are not always statistically significant, indicating that other factors such as access to healthcare, lifestyle, and socio-economic factors also influence the distribution of this disease. This study provides valuable insights for the development of gender-based heart disease prevention policies and introduces more targeted interventions.

This study analyzes the minimum age of marriage in Islamic jurisprudence and compares it with the positive law regulations in Indonesia and Malaysia. Using a normative legal method with comparative and conceptual approaches, the study draws on primary sources, including the Qur'an, hadith, Law Number 16 of 2019 on Marriage in Indonesia, and the Islamic Family Law (Federal Territories) Act 1984 in Malaysia. The analysis focuses on how Islamic legal principles concerning marriage eligibility are interpreted and incorporated into contemporary legal frameworks in both countries. The findings reveal that Islamic jurisprudence (fiqh) associates marital readiness with the concept of baligh (puberty) without prescribing a specific numerical age, whereas state law establishes fixed minimum age requirements to safeguard the rights and welfare of women and children. Indonesia sets the minimum marriage age at 19 years for both males and females, while Malaysia prescribes 18 years for males and 16 years for females, with judicial dispensation available in both jurisdictions under certain circumstances. These legal arrangements demonstrate each country's effort to harmonize classical Islamic jurisprudence with contemporary social protection objectives through institutional ijtihad, reflecting a balance between religious principles, legal certainty, and public welfare in regulating marriage.

Soft Tissue Tumor (STT) is an abnormal lump or swelling caused by new cell growth originating from connective tissue. Post-operative STT presents major nursing problems including acute pain, knowledge deficit, and risk of infection that require comprehensive nursing care. This scientific paper aims to describe nursing care for Mr. R with post-operative Soft Tissue Tumor (STT) Gluteal Sinistra in Mawar 2 Ward of RSUD dr. Soeselo Tegal Regency. The writing method used is descriptive with a case study plan through interviews, physical examination, observation, and documentation. Assessment was conducted on February 8, 2026 on Mr. R, a 37-year-old male, who underwent left gluteal tumor removal surgery on February 7, 2026. Assessment results identified three nursing diagnoses: acute pain related to physical injury agent (D.0077), knowledge deficit related to lack of information exposure (D.0111), and risk of infection evidenced by invasive procedure effects (D.0142). After nursing interventions for 2x24 hours on February 8–9, 2026, evaluation showed all three nursing diagnoses resolved: pain scale decreased from 6 to 2, the client was able to re-explain the tumor disease, and the surgical wound was clean without signs of infection. The conclusion of this nursing care shows that the application of deep breathing relaxation techniques, health education, and proper wound care are effective in addressing nursing problems in post-operative Soft Tissue Tumor patients.

Mouth breathing is a clinical condition characterized by mixed or additional breathing through the mouth that replaces the nasal breathing pattern. It is caused by mechanical factors such as septal deviation and adenotonsillar hyperplasia, inflammatory diseases such as allergic rhinitis, and habits. The purpose of this research is to determine the description of mouth breathing habits in GSA children at the Biruku Foundation, Bandung. This research was performed using descriptive method. The subjects were 15 autism spectrum disorder (ASD) collected by total sampling. The research was conducted by the mirror test examination. The results showed that 5 children have the mouth breathing habit (33%). Based on gender, 2 female children have the mouth breathing habit (50%) and 3 male children who have the mouth breathing habit (27.27%). This research shows that the percentage of mouth breathing habits in ASD children at the Biruku Foundation, Bandung, is quite high, with girls having a higher prevalence than boys.

Background: Adenoid hypertrophy is a condition characterized by enlargement of the adenoid tissue which can cause nasopharyngeal obstruction and potentially affect the function of the Eustachian tube. Dysfunction of the Eustachian tube may disrupt middle ear ventilation and increase the risk of otitis media. The degree of adenoid hypertrophy can be objectively assessed using a lateral nasopharyngeal radiograph by calculating the adenoid–nasopharyngeal ratio (A/N ratio). Objective: This study aimed to determine the relationship between adenoid hypertrophy based on the adenoid–nasopharyngeal ratio and the incidence of otitis media. Methods: This study was a quantitative research with an analytic observational design using a cross-sectional approach. Data were obtained from the medical records of patients with adenoid hypertrophy who underwent lateral nasopharyngeal radiographic examination at RSI Purwokerto from 2022 to 2025. The sample consisted of 31 patients who met the inclusion and exclusion criteria. Data analysis was performed using the Spearman correlation test because the data were not normally distributed based on the Shapiro–Wilk test. Results: The results showed that most of the subjects were male (17 subjects, 54.8%) and female (14 subjects, 45.2%). The median age of the subjects was 7 years with an age range of 4–9 years. The median adenoid–nasopharyngeal ratio was 0.90 with a range of 0.68–0.99. Otitis media was found in 11 subjects (35,5%), while 20 subjects (64,5%) did not experience otitis media. The Spearman correlation test showed a correlation coefficient of r = 0.015 with a p-value of 0.936 (p > 0.05), indicating that there was no significant relationship between the adenoid–nasopharyngeal ratio and the incidence of otitis media. Conclusion: There was no statistically significant relationship between adenoid hypertrophy based on the adenoid–nasopharyngeal ratio and the incidence of otitis media.

Diabetes Mellitus is a non-communicable disease with an increasing prevalence and has become a major public health concern globally and nationally. The incidence of diabetes mellitus is influenced by various individual and environmental factors. This study aimed to analyze the relationship between age, gender, and residential proximity to landfill areas and the incidence of diabetes mellitus in Bendosari District. A quantitative analytic observational design with a cross-sectional approach was employed. The study population consisted of 1,890 patient visit records recorded in the Management Information System of Bendosari Public Health Center in 2025. A total of 363 respondents were selected using proportionate stratified random sampling. Data were analyzed through univariate analysis, bivariate analysis using the Chi-Square test, and multivariate analysis using multiple logistic regression. The findings showed that age was significantly associated with diabetes mellitus incidence (p=0.000; OR=79.790; 95% CI=53.511–118.974). Gender was also significantly related to diabetes mellitus incidence (p=0.000; OR=0.298; 95% CI=0.203–0.435), indicating that females had a higher risk than males. In contrast, residential proximity to landfill areas was not significantly associated with diabetes mellitus incidence (p=0.308; OR=1.247; 95% CI=0.439–3.540). Multivariate analysis revealed that age and gender were the dominant factors influencing diabetes mellitus incidence, with the model explaining 56.1% of the variation. The study concludes that age and gender are significant determinants of diabetes mellitus incidence, whereas residential proximity to landfill areas has not been proven to significantly affect its occurrence.

Chronic rhinosinusitis (CRS) is a long-term inflammatory condition affecting the nasal mucosa and paranasal sinuses, which significantly impacts patients’ quality of life due to persistent and recurrent symptoms. Limited epidemiological data regarding CRS are available in Central Kalimantan, particularly at RSUD dr. Doris Sylvanus in Palangka Raya, prompting this study to determine its prevalence and patient distribution characteristics. This research employed a quantitative descriptive design with a cross-sectional approach. Data were collected from medical records of patients diagnosed with CRS in 2023 and 2024. Univariate analysis was conducted, and results were presented in tables and diagrams illustrating frequency distributions by year, gender, age, and main complaints. The findings showed a total of 118 CRS patients, with 53 cases in 2023 and 65 cases in 2024. The prevalence of CRS increased from 4.91% in 2023 to 10.83% in 2024. Based on gender, males accounted for 50.8% (60 patients), while females represented 49.2% (58 patients). The age group most affected was 46–55 years (31%), indicating a predominance among individuals of productive age. Nasal congestion was the most frequent primary complaint, reported by 35% of patients. The study concludes that the prevalence of CRS at RSUD dr. Doris Sylvanus increased notably from 2023 to 2024, with a slightly higher incidence among males in the productive age group. These findings highlight the need for enhanced preventive measures and early diagnosis to manage CRS more effectively in the local population.

Population growth is an important indicator in regional development planning because it influences the provision of public services, infrastructure development, and policy formulation. Accurate population estimation is therefore essential to support data-driven decision-making by local governments. This study aims to estimate the population growth rate of Serdang Bedagai Regency by applying data mining techniques using the Multiple Linear Regression method. The data used were obtained from the Central Statistics Agency (BPS) of Serdang Bedagai Regency for the period 2019–2023 and include the number of male and female residents. The research process involved several stages, including data collection, data preprocessing, model development, and statistical analysis. Based on the analysis, a regression model was obtained with the equation Y = 0 + 1.5558X1 + 0.4367X2, where Y represents the total population, X1 represents the number of male residents, and X2 represents the number of female residents. The results indicate an estimated population of 683,056 people in 2024, showing an increase compared to the previous year. These findings suggest that the Multiple Linear Regression method can provide reliable population estimates and serve as a useful reference for supporting evidence-based regional development planning and population management strategies in Serdang Bedagai Regency.

The article entitled “Gender Construction and Representation of Social Actors in the Drama Lutung Kasarung: A Critical Discourse Analysis by Theo van Leeuwen” aims to describe the representation of gender-based social actors through inclusion and exclusion strategies and to reveal the construction of gender ideology built in the drama text. This study uses a qualitative approach with a descriptive-analytical design. The research data source is the drama text Lutung Kasarung, while the analysis unit includes dialogue, narrative, and the depiction of characters who represent gender-based social actors. Data collection techniques are carried out through documentation by reading, identifying, and grouping data according to Theo van Leeuwen's analysis categories. The results of the study show that the inclusion strategy is more dominantly used to present male characters as strong, rational figures, and have authority in determining the course of the story. In contrast, female characters are represented in two patterns, namely the ideal passive woman and the dominant woman who is constructed negatively. In addition, the exclusion strategy is used to obscure the role of women in decision-making, thereby reinforcing gender marginalization. This study concludes that the drama Lutung Kasarung represents patriarchal ideology through discourse practices that shape power relations between men and women.

Stroke patients often experience mobility limitations, which impacts access to dental health services, including denture care. This condition can lead to unmanaged dentures, thus impairing masticatory function, nutritional status, and quality of life. A home care approach is one solution to improve access to dental services for patients with special needs. To report the management of direct removable denture repair in a single visit in a stroke patient using a home care approach and to evaluate the clinical outcomes. This study is a case report of a 77-year-old male patient with a history of recurrent stroke and limited mobility. Examination and treatment were performed at the patient's home. The direct removable denture repair was performed using autopolymerizing acrylic resin in a single visit. Following repair, the denture demonstrated improved retention and stability and was reusable. The patient reported improved comfort while eating without any pain or post-procedure complications. One-visit denture repair through a home care approach is an effective and efficient method for stroke patients with limited mobility and has the potential to improve their quality of life through rapid restoration of oral function.

Indonesia is recognized as a country with abundant mineral resources; however, the expansion of the mining sector has generated multidimensional moral inequality, encompassing an imbalance in economic benefit distribution between corporations and local communities, disregard for the intrinsic value of nature, and the marginalization of affected communities from decision-making. The dominance of the anthropocentric paradigm, which places humans as the center of value, is the root cause of this problem. This study aims to analyze moral inequality in Indonesia's mining practices, examine the anthropocentric paradigm in natural resource management, and formulate biocentric ethics as a just alternative. A qualitative approach with library research method was employed, collecting data from national scientific journals, official government reports, and environmental ethics literature, analyzed descriptively-critically through content analysis technique. Findings reveal three interrelated dimensions of moral inequality: inequality in benefit and burden distribution, inequality in recognizing the intrinsic value of nature, and inequality in participatory decision-making. A reconstruction of biocentric ethics grounded in the principles of non-maleficence, noninterference, fidelity, and restitutive justice offers a comprehensive value framework to address ecological moral deficits. This study concludes that a paradigmatic transformation from anthropocentrism to biocentrism, through Free Prior and Informed Consent implementation, the polluter pays principle, and care ethics-based governance, is a fundamental step toward ethical and sustainable mining practices.

High-quality forage selection is a central factor in improving Bali cattle performance, particularly in smallholder systems that rely heavily on local feed resources. This study evaluated the effects of odot grass (Pennisetum purpureum cv. Mott) and pakchong grass (Pennisetum purpureum cv. Thailand) on feed intake, average daily gain, and feed conversion ratio of male Bali cattle. The experiment was conducted for 30 days from February to March 2026 at CV. RnB Farm, Gorontalo Regency. Nine male Bali cattle with relatively homogeneous initial body weights of 150–200 kg was assigned to a completely randomized design with three treatments and three replications. The treatments were P0, field grass as the control; P1, 100% odot grass plus concentrate; and P2, 100% pakchong grass plus concentrate. Dry matter intake did not differ significantly among treatments, with values of 6.47 ± 0.19, 6.52 ± 0.19, and 6.55 ± 0.16 kg/head/day for P0, P1, and P2, respectively. In contrast, average daily gain differed significantly, with the highest value observed in P2 at 0.56 ± 0.08 kg/head/day, followed by P1 at 0.52 ± 0.09 kg/head/day and P0 at 0.45 ± 0.06 kg/head/day. Feed conversion ratio also differed significantly, with the most efficient value recorded in P2 at 11.98 ± 2.10. These findings indicate that pakchong grass combined with concentrate provides the best feed efficiency and growth performance, while odot grass remains a promising alternative forage for improving Bali cattle productivity.

Cigarette smoke is a major source of free radicals that can cause various health problems, including disturbances in the male reproductive system. Nicotine and other harmful compounds in cigarettes increase oxidative stress and interfere with spermatogenesis. Gotu Kola (Centella asiatica) is a medicinal plant known for its antioxidant properties that may help neutralize free radicals. This study aimed to determine the effect of Gotu Kola leaf extract on the histopathological features of the testes in male Wistar rats exposed to cigarette smoke. An experimental study using a Post-Test Only Control Group Design was conducted on 24 rats divided into six groups: a normal group, a negative control group exposed to cigarette smoke, a positive control group treated with vitamin E, and three treatment groups receiving Gotu Kola extract at doses of 120, 180, and 240 mg/kg body weight for 28 days. The observed parameters were Leydig cell count and seminiferous tubule diameter. One-way ANOVA analysis showed that Gotu Kola extract significantly increased Leydig cell numbers and seminiferous tubule diameter in all treatment groups compared to the negative control group (p < 0.05). Post hoc analysis demonstrated significant differences in tubule diameter, with the highest improvement observed at the 240 mg/kg body weight dose. These findings indicate that Gotu Kola extract has potential protective effects against testicular damage caused by cigarette smoke exposure.

Bariatric surgery is effective in treating obesity and type 2 diabetes mellitus (T2DM); however, pregnancy occurring within 12–24 months after surgery carries significant risks. This report presents a complex pregnancy case in a patient with a history of sleeve gastrectomy, post-hemithyroidectomy hypothyroidism, and T2DM. A 29-year-old primigravida conceived 2 months after undergoing sleeve gastrectomy, which successfully induced T2DM remission, with HbA1c decreasing from 11% to 5.5%. Although glycemic control and euthyroid status were maintained throughout pregnancy, the patient developed severe preeclampsia at 35–36 weeks of gestation, complicated by intrauterine growth restriction (IUGR) and oligohydramnios. An emergency cesarean section delivered a male infant weighing 2000 grams with Apgar scores of 8 and 9 at the first and fifth minutes, respectively. The neonate required 14 days of NICU care due to respiratory distress syndrome, respiratory failure, and hyperbilirubinemia. Maternal gestational weight gain was suboptimal at only 4 kg, below the recommended range for pregnant women with obesity. This case highlights the importance of adhering to the recommended surgery-to-conception interval following bariatric surgery. Early pregnancy after surgery, combined with multiple metabolic comorbidities, may contribute to adverse maternal and neonatal outcomes. Multidisciplinary management, comprehensive nutritional monitoring, and optimization of comorbidities before conception are essential to improve pregnancy outcomes in this population.

This study examines the tradition of nikah malem songo within the framework of cultural Islam as a form of acculturation between Islamic teachings and local traditions in the coastal community of Tuban, East Java. The research aims to analyze the acculturation process, identify the religious and cultural values embedded in the tradition, and explore its relevance in contemporary society. A qualitative descriptive approach with a case study design was employed. Data were collected through observation, in-depth interviews, and documentation involving religious leaders, community figures, and local residents. The findings show that nikah malem songo reflects a harmonious integration of Islamic principles and local cultural practices while maintaining the essential requirements of Islamic marriage. The tradition also contains symbolic elements, such as selecting a sacred time believed to bring blessings. In addition, the practice serves as a social mechanism that strengthens community solidarity, reinforces cultural identity, and transmits values across generations. Although challenged by modernization, globalization, and puritan religious views, the tradition continues to survive through reinterpretation and selective preservation. The study concludes that nikah malem songo represents an inclusive and contextual form of Islam capable of adapting to changing social dynamics.

This study aims to examine the concept of crisis response in the Qur'an and its relevance to medical triage practices in contemporary healthcare settings. The method used is a qualitative approach with thematic interpretation (maudhu’i) of Qur’anic verses related to saving lives, emergency conditions (darurah), justice, responsibility, and human limitations. The analysis focuses on how Qur’anic ethical principles can provide guidance in situations where medical resources are limited and difficult decisions must be made. The results show that the Qur'an offers an ethical framework that emphasizes the priority of saving human life, flexibility in emergencies, justice in decision-making, proportional consideration of benefit and harm, and recognition of human limitations in determining outcomes. These principles are closely aligned with the values of modern medical bioethics, namely beneficence, non-maleficence, autonomy, and justice. Therefore, the Qur'anic perspective can serve as an integrative ethical foundation for medical triage practices, not only in terms of professional and interpersonal responsibility, but also as part of spiritual accountability before God. This research contributes to the development of interdisciplinary studies between Qur'anic studies, Islamic ethics, and medical bioethics.    

This study aims to examine the concept of crisis response in the Qur'an and its relevance to medical triage practices in contemporary healthcare settings. The method used is a qualitative approach with thematic interpretation (maudhu’i) of Qur’anic verses related to saving lives, emergency conditions (darurah), justice, responsibility, and human limitations. The analysis focuses on how Qur’anic ethical principles can provide guidance in situations where medical resources are limited and difficult decisions must be made. The results show that the Qur'an offers an ethical framework that emphasizes the priority of saving human life, flexibility in emergencies, justice in decision-making, proportional consideration of benefit and harm, and recognition of human limitations in determining outcomes. These principles are closely aligned with the values of modern medical bioethics, namely beneficence, non-maleficence, autonomy, and justice. Therefore, the Qur'anic perspective can serve as an integrative ethical foundation for medical triage practices, not only in terms of professional and interpersonal responsibility, but also as part of spiritual accountability before God. This research contributes to the development of interdisciplinary studies between Qur'anic studies, Islamic ethics, and medical bioethics.    

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

This study aims to (1) describe the process of developing the Smart Box Aku Cinta Pancasila learning media for first-grade elementary school students, (2) describe the validity of the Smart Box Aku Cinta Pancasila learning media, and (3) describe students’ responses to the Smart Box Aku Cinta Pancasila learning media. This research is a developmental study using the ADDIE model (Analyze, Design, Development, Implementation, and Evaluation). The study was conducted at UPT SD Negeri 253 Gresik during the odd semester. The research subjects consisted of 25 students, comprising 10 male students and 15 female students. The data collection techniques included interviews, media expert validation questionnaires, material expert validation questionnaires, learning outcomes test and student response questionnaires. The results of the study indicate that the Smart Box Aku Cinta Pancasila learning media obtained a media expert validation score of 96,25% with a very valid category, a material expert validation score of 97,50% with a very valid category, and a student response score of 97,2% with a very good category. Based on these results, the Smart Box Aku Cinta Pancasila learning media is considered valid and get a positive response, and therefore suitable for use as a learning media for Pancasila Education for first-grade elementary school students.