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Di era Industri 5.0, adaptabilitas tenaga kerja menjadi urgensi utama karena terjadinya pergeseran paradigma dari fokus pada otomatisasi dan efisiensi menuju kolaborasi harmonis antara manusia dan teknologi yang berpusat pada manusia (human-centric), berkelanjutan, dan resilien. Penelitian ini menggunakan metode Systematic Literature Review (SLR) terhadap 40 artikel jurnal nasional dan internasional yang diterbitkan tahun 2020–2025 dari basis data Google Scholar, Scopus, dan Garuda. Tujuan penelitian adalah mengidentifikasi strategi upskilling dan reskilling yang efektif sebagai mekanisme adaptabilitas tenaga kerja terhadap disrupsi AI dan otomatisasi. Hasil kajian menunjukkan bahwa: (1) kesenjangan keterampilan global merupakan ancaman nyata dengan 50% karyawan membutuhkan reskilling pada 2025; (2) strategi upskilling dan reskilling yang efektif mencakup pembelajaran berbasis proyek, microlearning, platform digital adaptif, dan kemitraan industri; (3) dukungan organisasi, kepemimpinan transformasional, dan budaya belajar berkelanjutan merupakan faktor penentu keberhasilan; serta (4) hambatan utama implementasi meliputi keterbatasan anggaran, resistensi perubahan, dan kesenjangan infrastruktur digital. Temuan ini menegaskan bahwa investasi pada pengembangan modal manusia melalui program upskilling dan reskilling merupakan imperatif strategis untuk menjaga ketahanan organisasi dan daya saing tenaga kerja di era transformasi digital.

The Free Health Check-up (CKG) is a government program designed to strengthen promotive and preventive health efforts through the early detection of risk factors, pre-disease conditions, and diseases across the community according to the life-cycle approach. As a relatively new initiative, the implementation of the CKG program in primary healthcare settings still requires further evaluation to assess implementation readiness, digital support systems, and community participation. This literature review aimed to examine the implementation of the Free Health Check-up Program in primary healthcare services. Relevant literature was retrieved from the Google Scholar database using the keyword "implementation of the free health check-up program" and was limited to open-access, full-text articles published between 2025 and 2026. The search identified eight eligible articles, which were extracted and analyzed in this review. The synthesis revealed three major themes in the implementation of the CKG program: (1) primary healthcare service readiness, (2) digitalization and reporting systems, and (3) community participation and communication strategies. Primary healthcare readiness includes the availability of human resources, infrastructure, medical equipment, consumable medical supplies, funding, service workflows, and cross-sectoral coordination. Digitalization through the SATUSEHATplatform and integrated reporting systems has the potential to improve service efficiency; however, challenges remain regarding digital literacy, internet connectivity, and the technical capacity of healthcare personnel. Community participation is influenced by knowledge, attitudes, the roles of community health volunteers, teachers, healthcare workers, and communication strategies tailored to the characteristics of the target population. The successful implementation of the CKG program requires strengthening primary healthcare systems, optimizing digital health platforms, and adopting community-based communication strategies to ensure the program is more effective, inclusive, and sustainable.

The development of Artificial Intelligence (AI) has driven significant transformation in hospital management, particularly in operational efficiency, service quality, and patient safety. This study aims to analyze the implementation of AI in hospital management based on recent scientific evidence from 2020 to 2026. The method used was a systematic review guided by the PRISMA 2020 framework. Literature was retrieved from PubMed, ScienceDirect, SpringerLink, Google Scholar, and ProQuest. From 360 identified articles, a stepwise selection process was conducted, resulting in 15 articles that met the inclusion criteria. The findings indicate that AI contributes to improved operational efficiency through patient flow optimization, operating room management, workforce scheduling, and electronic medical record management. AI also enhances service quality through predictive data analytics and supports patient safety through risk detection and early warning systems. In conclusion, AI has strong strategic potential to support modern hospital management. However, its implementation still faces several challenges, including human resource readiness, data security, algorithmic bias, system interoperability, and investment requirements. Therefore, AI implementation should be carried out in a planned, ethical manner and evaluated from a health economics perspective.

This literature review analyzes the impact of data privacy issues on consumer usage intention in Indonesian e-commerce platforms. The study aims to map privacy threats and understand the phenomenon of the privacy paradox in the context of digital retail. Using a literature review method, this study synthesized findings from international journals published in the last five years from Scopus, Web of Science, and Google Scholar databases. The results show that excessive data collection, unauthorized secondary use, and data breaches significantly increase consumer privacy concerns. However, the research also confirms a privacy paradox, where consumers willingly share personal data to gain shopping convenience and promotions. The findings highlight that strong brand trust and a seamless user experience can effectively mitigate these privacy fears. Practically, this study recommends that e-commerce companies implement the Privacy by Design framework, utilize dynamic passwords (OTP), and provide transparent privacy settings as a competitive marketing advantage. Future research should explore specific regional demographics and the direct impact of new technologies like AI chatbots on consumer security perceptions.

The implementation of Electronic Medical Records (EMR) has become an essential part of digital transformation in the healthcare sector, aiming to improve the quality, effectiveness, efficiency, and continuity of healthcare services. In Indonesia, the implementation of EMR is supported by the Regulation of the Minister of Health Number 24 of 2022, which mandates healthcare facilities to adopt electronic medical records. However, the implementation process is often challenged by various technical and non-technical factors that may affect its success. This study aims to analyze the success factors and barriers to EMR implementation in hospitals through a literature review approach. The research method used was a literature review by examining and analyzing 11 scientific articles obtained from Google Scholar and other relevant scientific sources. The findings indicate that the success of EMR implementation is influenced by three main aspects, namely human, organizational, and technological factors. Supporting factors include management commitment, user readiness, continuous training, availability of information technology infrastructure, system quality, and organizational support. Meanwhile, common barriers include limited digital literacy among healthcare workers, insufficient information technology personnel, unstable internet connectivity, system errors, inadequate facilities and infrastructure, budget limitations, and the absence of specific standard operating procedures. Furthermore, EMR implementation provides significant benefits, such as improving service efficiency, facilitating access to patient information, enhancing documentation quality, supporting communication among healthcare professionals, and increasing patient safety. Therefore, successful EMR implementation requires synergy between human resources, organizational readiness, and technological infrastructure to achieve optimal healthcare service delivery.

Guided Bone Regeneration (GBR) relies on a barrier membrane to prevent soft tissue invasion in the wound area and maintain space for bone formation. Conventional membranes generally function as a passive barrier without enhancing osteogenesis. Membranes fabricated with the addition of β-TCP were developed to enhance membrane bioactivity. This review aims to evaluate the role of β-TCP as a bioactive component in barrier membranes used in GBR procedures. The study used a narrative review approach with literature sources from PubMed, Google Scholar, and ScienceDirect in the period 2016–2026. The keywords used included “guided bone regeneration," “barrier membrane," and “β-tricalcium phosphate." The selected articles were English-language experimental studies with relevant topics. A total of 7 articles met the inclusion criteria. The incorporation of native β-TCP showed increased osteoconductivity, hydrophilicity, and mechanical strength of the membrane. The release of calcium and phosphate ions plays a role in increasing osteoblast proliferation and osteogenic marker expression. In vitro and in vivo studies also demonstrated increased new bone formation and improved regeneration space maintenance compared to conventional membranes. The optimal concentration of β-TCP varies depending on the polymer matrix. β-TCP-based membranes have the potential to act as bioactive barrier membranes that not only act as a barrier but also support bone regeneration. Further research, particularly human clinical trials, is needed to confirm their effectiveness and safety.

Literature reviews play a crucial role in scientific research because they serve to integrate previous research findings to build a conceptual framework that supports new research. However, in the practice of writing Classroom Action Research (CAR) articles, previous research is often presented descriptively without adequate conceptual synthesis. This study aims to systematically analyze the practice of citing prior research in the literature review of CAR articles as part of a systematic literature review. The study employs a Systematic Literature Review (SLR) approach following the PRISMA 2020 guidelines, which include the stages of identification, screening, eligibility assessment, and literature synthesis. Literature sources were obtained from various academic databases such as Scopus, Web of Science, Google Scholar, and Crossref using keywords relevant to classroom action research and literature reviews. Data analysis was conducted through thematic analysis to identify patterns and trends in the writing practices of previous research in the literature review of classroom action research. The results indicate that literature review writing in action research articles is still dominated by a descriptive approach that presents previous research sequentially without adequate conceptual integration and thematic synthesis. Furthermore, critical evaluation of prior research methodologies remains limited, meaning that literature reviews do not yet fully serve as a foundation for developing the theoretical framework of the research. The findings highlight the importance of applying a systematic literature review approach in writing PTK literature reviews to produce a more analytical, systematic, and integrated synthesis of the literature.

Background: Labor is a physiological process that is commonly accompanied by pain, causing discomfort, anxiety, and fear that may interfere with maternal well-being and labor progress. Effleurage massage is a complementary, non-pharmacological intervention used to reduce labor pain. Purpose: This study aimed to evaluate the effectiveness of effleurage massage in reducing pain intensity during the first stage of labor. Method: A literature review was conducted using articles retrieved from Google Scholar. An initial search identified 45 articles, and after screening based on publication year (2021–2026), relevance, and inclusion criteria, 10 research articles were included for analysis. Data were extracted and synthesized descriptively. Results: The findings consistently showed that effleurage massage reduced labor pain by promoting relaxation, decreasing muscle tension, improving blood circulation, and stimulating endorphin release through the gate control mechanism. Most studies also reported improved maternal comfort during labor. Conclusion: In conclusion, effleurage massage is an effective, safe, affordable, and easy-to-apply complementary therapy that can be integrated into midwifery care to reduce labor pain and enhance maternal comfort.  

In order to raise the standard of healthcare services in the contemporary period, digital transformation in hospital management has become a phenomena. The purpose of this study is to investigate the adoption, advantages, difficulties, and success aspects of digital transformation in healthcare facilities. A literature review employing a narrative review system was the methodology. 14 papers that met the inclusion requirements were found using data sources from Google Scholar, PubMed, and ScienceDirect databases with publication years ranging from 2020 to 2025. To determine the primary study themes, data analysis was carried out utilising a thematic synthesis approach. According to the study's findings, digital transformation can enhance operational effectiveness, service quality, and patient safety by using technology including electronic health records (EHR), telemedicine, and hospital management information systems. However, there are still a number of obstacles to its adoption, such as inadequate infrastructure, inadequate human resource competency, expensive investment costs, and data security threats. Significant barriers also include a lack of system integration and opposition to change. Government policies and regulatory assistance have an impact on the success of digital transformation in hospital administration.

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that may persist into adulthood and affect academic, social, and occupational functioning. In adult patients, ADHD is frequently associated with an increased risk of Substance Use Disorder (SUD), raising concerns regarding the potential for misuse and dependence related to stimulant medications used in ADHD therapy. This study aimed to evaluate the effectiveness of pharmacotherapy for adult ADHD and to review the risk of stimulant misuse and dependence based on current scientific evidence. The method employed in this study was a literature review using data obtained from national and international journals indexed in Scopus, PubMed, and Google Scholar published between 2017 and 2026. The findings indicated that stimulant medications, such as methylphenidate and amphetamine, were effective in reducing the core symptoms of ADHD by increasing dopamine and norepinephrine activity in the central nervous system. Most studies reported that the use of stimulant medications at therapeutic doses and under medical supervision was not significantly associated with an increased risk of substance misuse or dependence. The risk of misuse was more commonly observed in cases involving non-medical use and inadequate clinical monitoring. In addition to pharmacological therapy, non-pharmacological approaches such as cognitive behavioral therapy (CBT) also contributed to improving treatment outcomes and patients’ quality of life. Therefore, the use of stimulant medications in adult ADHD patients may be considered relatively safe and effective when administered rationally, individually, and under appropriate medical supervision.

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that may persist into adulthood and affect academic, social, and occupational functioning. In adult patients, ADHD is frequently associated with an increased risk of Substance Use Disorder (SUD), raising concerns regarding the potential for misuse and dependence related to stimulant medications used in ADHD therapy. This study aimed to evaluate the effectiveness of pharmacotherapy for adult ADHD and to review the risk of stimulant misuse and dependence based on current scientific evidence. The method employed in this study was a literature review using data obtained from national and international journals indexed in Scopus, PubMed, and Google Scholar published between 2017 and 2026. The findings indicated that stimulant medications, such as methylphenidate and amphetamine, were effective in reducing the core symptoms of ADHD by increasing dopamine and norepinephrine activity in the central nervous system. Most studies reported that the use of stimulant medications at therapeutic doses and under medical supervision was not significantly associated with an increased risk of substance misuse or dependence. The risk of misuse was more commonly observed in cases involving non-medical use and inadequate clinical monitoring. In addition to pharmacological therapy, non-pharmacological approaches such as cognitive behavioral therapy (CBT) also contributed to improving treatment outcomes and patients’ quality of life. Therefore, the use of stimulant medications in adult ADHD patients may be considered relatively safe and effective when administered rationally, individually, and under appropriate medical supervision.

Aerobic capacity, commonly measured by maximal oxygen uptake (VO₂max), is a key indicator of physical fitness and athletic performance, particularly in endurance sports. Recent attention has focused on the role of respiratory muscle function in supporting exercise performance, as respiratory muscle fatigue during high-intensity or prolonged activity may reduce ventilatory efficiency and exercise tolerance. This literature review aims to examine current evidence regarding the effects of Respiratory Muscle Training (RMT), including Inspiratory Muscle Training (IMT), on aerobic capacity in athletes. Relevant studies were identified through electronic databases such as PubMed, Scopus, and Google Scholar using keywords related to respiratory muscle training, VO₂max, and athletes. The reviewed studies generally reported improvements in inspiratory muscle strength, reduced respiratory muscle fatigue, and enhanced ventilatory efficiency following RMT interventions. These physiological adaptations may contribute to better exercise tolerance and overall athletic performance. However, evidence regarding direct improvements in VO₂max remains inconsistent across studies. The findings suggest that RMT can be used as a complementary strategy alongside conventional training programs to support aerobic performance. In addition, improved respiratory muscle function may provide benefits in health promotion and rehabilitation by reducing dyspnea and increasing exercise tolerance. Further well-designed studies are needed to clarify the extent of RMT’s contribution to improving VO₂max in athletic populations.

Aerobic capacity, commonly measured by maximal oxygen uptake (VO₂max), is a key indicator of physical fitness and athletic performance, particularly in endurance sports. Recent attention has focused on the role of respiratory muscle function in supporting exercise performance, as respiratory muscle fatigue during high-intensity or prolonged activity may reduce ventilatory efficiency and exercise tolerance. This literature review aims to examine current evidence regarding the effects of Respiratory Muscle Training (RMT), including Inspiratory Muscle Training (IMT), on aerobic capacity in athletes. Relevant studies were identified through electronic databases such as PubMed, Scopus, and Google Scholar using keywords related to respiratory muscle training, VO₂max, and athletes. The reviewed studies generally reported improvements in inspiratory muscle strength, reduced respiratory muscle fatigue, and enhanced ventilatory efficiency following RMT interventions. These physiological adaptations may contribute to better exercise tolerance and overall athletic performance. However, evidence regarding direct improvements in VO₂max remains inconsistent across studies. The findings suggest that RMT can be used as a complementary strategy alongside conventional training programs to support aerobic performance. In addition, improved respiratory muscle function may provide benefits in health promotion and rehabilitation by reducing dyspnea and increasing exercise tolerance. Further well-designed studies are needed to clarify the extent of RMT’s contribution to improving VO₂max in athletic populations.

The Free Nutritious Meal Program (MBG) is a free school lunch initiative in Indonesia introduced during the administration of Prabowo Subianto. This study aims to examine the effectiveness of the government's MBG (Free Nutritious Meal) program on kindergarten students' learning interest through a literature review approach. The background of this study is based on the issue of low student learning interest, which is influenced not only by pedagogical factors but also by physical conditions, particularly nutritional intake. This research employed a qualitative approach using a literature review method. The data sources consisted of scientific articles published within the last five years and accessed through Google Scholar. Data were collected through documentation studies, while thematic synthesis was used for data analysis. The findings indicate that the MBG program has a significant positive impact on improving students' learning interest, particularly in terms of attention, motivation, participation, and attendance. The results also reveal that meeting students' physiological needs contributes to their cognitive and emotional readiness to learn. However, the effectiveness of the program is influenced by the quality of its implementation and management in the field. Therefore, more optimal program management and continuous evaluation are needed to maximize its impact on improving the quality of learning.

Agentic artificial intelligence (AI) systems capable of autonomous goal-directed behavior, multi-step planning, tool use, multi-agent coordination, and iterative self-correction represent a transition from passive clinical AI tools toward systems that can participate in complex healthcare workflows. However, empirical evidence remains fragmented across clinical decision support, patient monitoring, and administrative applications, and no systematic synthesis has evaluated which agentic principles have been technically demonstrated and which have accumulated sufficient evidence to support responsible clinical deployment. We conducted a PRISMA-informed systematic review of peer-reviewed empirical studies published between January 2025 and April 2026. Searches across five bibliographic databases and Google Scholar, supplemented by citation tracking, identified 443 unique records for screening, of which 25 met the predefined PICOS and quality appraisal criteria. Evidence was synthesized using an evidence-informed seven-principle framework derived from the integration of agentic AI, clinical AI, and healthcare governance literature. This framework provides a structured lens for examining how agentic principles are evaluated individually and in combination, enabling a deployment-readiness perspective that extends beyond capability-focused assessments alone. The evidence base was concentrated on technical capability principles, whereas human oversight, safety, compliance, and equity-related evaluation received comparatively limited attention. Most studies remained at the laboratory, benchmark, or proof-of-concept stage, and none reported demographic-stratified performance outcomes. Overall, the findings suggest a structural asymmetry in agentic healthcare AI: empirical research is advancing agentic capabilities more rapidly than it is generating evidence for the oversight, safety, equity, and governance mechanisms required for responsible clinical translation.

Risk factors for melasma have been identified at several points such as the use of birth control pills, cosmetics, sun exposure, estrogen therapy, decreased thyroid and ovarian function, ovarian tumors, nutrition, drugs that are classified as phototoxic or photoallergic, and epilepsy drugs. This article aims to determine the incidence of melasma and its risk factors. This study uses articles collected from the Google Scholar database. The data collection step uses the keyword "Risk Factor Melasma" according to the title and keyword criteria. The articles used are publications in the 2018-2023 year range. The stages of analysis are carried out using VOSviewer software for visualization and trend analysis in the form of bibliometric maps. The bibliometric approach was applied to identify publication patterns, research developments, and relationships among topics related to melasma risk factors. Based on the visualization results, 100 selected documents were published within 5 years, from 2018 to 2023. The findings provide an overview of the main research trends and contribute to a better understanding of the incidence of melasma and the factors associated with its occurrence

Dengue fever remains a major global health challenge, particularly in tropical regions, due to the high transmission of Dengue virus by Aedes aegypti and the limited sustainability of current control strategies. Artocarpus odoratissimus, an endemic Bornean plant, contains diverse secondary metabolites with potential pharmacological activities; however, a systematic synthesis of its biomedical relevance to Dengue is still lacking. This study aimed to systematically evaluate the biomedical potential of A. odoratissimus in Dengue prevention and control through a systematic literature review. This study employed a systematic literature review method following the PRISMA 2020 guidelines. Literature searches were conducted in Scopus, ScienceDirect, SpringerLink, PubMed, Google Scholar, Garuda, SINTA, and other relevant scientific databases for publications from January 2016 to February 2026. A total of 303 records were identified, and after duplicate removal, title and abstract screening, and full-text eligibility assessment, 23 studies were included for narrative synthesis. The findings revealed that A. odoratissimus contains major bioactive compounds, including flavonoids, phenolics, arylbenzofurans, stilbenoids, and prenylated chalcones, which demonstrate antioxidant, anti-inflammatory, immunomodulatory, and potential antiviral activities based on in vitro and molecular docking studies. Fruit peel, seeds, and stem bark exhibited the strongest biological evidence, particularly in reducing oxidative stress, inhibiting inflammatory mediators, and potentially interacting with Dengue viral target proteins. Furthermore, several species within the Artocarpus genus showed larvicidal and ovicidal activities against Aedes aegypti, highlighting the potential development of A. odoratissimus as a plant-based biolarvicide candidate.

Dengue fever remains a major global health challenge, particularly in tropical regions, due to the high transmission of Dengue virus by Aedes aegypti and the limited sustainability of current control strategies. Artocarpus odoratissimus, an endemic Bornean plant, contains diverse secondary metabolites with potential pharmacological activities; however, a systematic synthesis of its biomedical relevance to Dengue is still lacking. This study aimed to systematically evaluate the biomedical potential of A. odoratissimus in Dengue prevention and control through a systematic literature review. This study employed a systematic literature review method following the PRISMA 2020 guidelines. Literature searches were conducted in Scopus, ScienceDirect, SpringerLink, PubMed, Google Scholar, Garuda, SINTA, and other relevant scientific databases for publications from January 2016 to February 2026. A total of 303 records were identified, and after duplicate removal, title and abstract screening, and full-text eligibility assessment, 23 studies were included for narrative synthesis. The findings revealed that A. odoratissimus contains major bioactive compounds, including flavonoids, phenolics, arylbenzofurans, stilbenoids, and prenylated chalcones, which demonstrate antioxidant, anti-inflammatory, immunomodulatory, and potential antiviral activities based on in vitro and molecular docking studies. Fruit peel, seeds, and stem bark exhibited the strongest biological evidence, particularly in reducing oxidative stress, inhibiting inflammatory mediators, and potentially interacting with Dengue viral target proteins. Furthermore, several species within the Artocarpus genus showed larvicidal and ovicidal activities against Aedes aegypti, highlighting the potential development of A. odoratissimus as a plant-based biolarvicide candidate.

Allergic rhinitis (AR) is a chronic inflammatory disorder of the nasal mucosa mediated by immunoglobulin E (IgE) in response to allergen exposure. This condition has become a significant global health concern because of its increasing prevalence and substantial impact on quality of life, sleep, cognitive function, and work productivity. AR is also commonly associated with other atopic diseases, including asthma and atopic dermatitis. This article aims to review the current understanding of allergic rhinitis, focusing on epidemiology, pathophysiology, clinical manifestations, diagnostic approaches, and evidence-based management strategies. This study used a narrative literature review method by analyzing scientific articles, clinical guidelines, and peer-reviewed journals published between 2015 and 2025. Literature sources were obtained from PubMed, Google Scholar, and relevant medical databases using keywords related to allergic rhinitis, IgE, diagnosis, and immunotherapy. The findings indicate that allergic rhinitis involves complex immune mechanisms characterized by Th2 lymphocyte activation, IgE production, and inflammatory mediator release. Diagnosis is primarily established clinically and supported by allergy testing such as skin prick tests or serum-specific IgE measurement. Intranasal corticosteroids remain the first-line therapy for moderate to severe cases, while antihistamines and leukotriene receptor antagonists are used as adjunctive therapies. Allergen immunotherapy has shown effectiveness in modifying disease progression and improving long-term outcomes. In conclusion, allergic rhinitis is a manageable chronic disease that requires a comprehensive and individualized treatment approach involving environmental control, pharmacotherapy, and immunotherapy.

This study aims to map the trends, integration forms, effectiveness, and contribution of ethnomathematics in elementary school mathematics learning toward national cultural preservation. A systematic literature review (SLR) approach following the PRISMA 2020 protocol was employed. Searches across four academic databases (Scopus, Google Scholar, CrossRef, and Semantic Scholar) yielded 1,176 articles, from which 30 articles met the inclusion criteria. Results indicate that ethnomathematics research in elementary schools has increased significantly during 2023–2026, particularly following the implementation of Kurikulum Merdeka. The three most dominant forms of integration are digital modules and media (53.3%), traditional games (33.3%), and ethnomathematics-based worksheets (13.3%). Geometry and measurement is the most researched mathematics topic (50.0%), and conceptual understanding shows the most significant improvement (40.0%). Beyond improving mathematics achievement, ethnomathematics integration contributes to cultural preservation through cultural contextualization in learning (60.0%), strengthening cultural identity and values (26.7%), and active local cultural preservation (10.0%). The study recommends teacher training, curriculum policy strengthening, cross-sector collaboration, and further research to sustain ethnomathematics implementation in Indonesian elementary schools.