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Background: Hyperuricemia represents a medical condition marked by elevated concentrations of uric acid within the bloodstream, potentially triggering gout alongside various metabolic disorders. Central obesity has been identified as a contributing factor to rising uric acid concentrations, measurable through waist circumference assessment. Methods: An analytic observational design utilizing a cross-sectional approach was employed in this investigation, encompassing 100 male participants characterized by sedentary lifestyles who were employed as office workers in Medan City, North Sumatra Province. Waist circumference measurements were obtained using a flexible measuring tape, while uric acid concentrations were determined through Point of Care Test (POCT) devices. Statistical evaluation was conducted via the Chi-Square test, applying a significance threshold of 0.05. Results: Among all participants, 64 individuals (64%) exhibited waist circumference measurements indicative of central obesity, whereas 56 individuals (56%) demonstrated hyperuricemic conditions. Statistical evaluation revealed a significant association between waist circumference measurements and uric acid concentrations, evidenced by a p-value of 0.000 (p < 0.05). Conclusion: A meaningful correlation exists between waist circumference and uric acid concentrations among males engaged in sedentary occupations.

Diabetes mellitus (DM) is a metabolic disease characterized by elevated blood glucose levels. This condition includes several types, such as type 1 and type 2 diabetes. It occurs when the body is unable to produce enough insulin, experiences impaired insulin function, or faces a combination of both. As a result, glucose cannot be effectively absorbed by the body’s cells and accumulates in the bloodstream, leading to high blood sugar or hyperglycemia. If this condition persists, the buildup of glucose can cause various disorders in different organs. Without proper management, diabetes may lead to severe and life-threatening complications. Chronic hyperglycemia in diabetic patients is associated with long-term damage, dysfunction, and even failure of vital organs such as the eyes, kidneys, nerves, heart, and blood vessels. In this activity, percentage-based methods and demonstrations of blood glucose testing were used as educational tools for students. The results showed that students’ awareness of the dangers of elevated blood sugar levels remains low. Many of them are still unfamiliar with the importance of regular blood glucose monitoring and maintaining a healthy lifestyle to prevent diabetes. Therefore, continuous efforts are needed to provide education and outreach on the prevention and early management of diabetes mellitus.

Hyperlipidemia is a condition in which lipid levels in the bloodstream (plasma) experience an imbalance in lipid levels, although it does not show severe symptoms but can trigger various serious diseases. Statins are used as the main therapy for antidyslipidemia, but with long-term use, statins cause various side effects such as muscle pain, muscle disorders and muscle discomfort. Indonesia has a variety of plants that have benefits for lowering blood cholesterol levels. To determine the potential of metabolite compounds contained in several plants as HMG-COA Reductase inhibitors, research can be carried out using molecular docking. The purpose of this literature study is to determine the comparison of compounds that have HMG-COA Reductase inhibitor inhibitor activity. The method used in compiling this literature study is from various national and international scientific articles published in the period 2020-2025. The natural compounds that have been studied have significant inhibitory activity against the HMG-CoA Reductase enzyme, namely from the 10 plants studied, Rhodomyrtus tomentosa has the best activity in inhibiting the HMG-CoA Reductase enzyme with an Affinity of the Binding value of -11.4 so that it has the potential to be further developed as a natural anti-cholesterol drug.

Background: Diabetes mellitus is a metabolic disorder caused by increased blood glucose levels in the bloodstream or hyperglycemia, which is caused by abnormalities in insulin secretion or abnormalities in insulin work. Physical activity can also affect blood sugar levels, one of which is the physical activity of foot exercises which is recommended for people with diabetes mellitus. Objective: To determine the effectiveness of foot exercise activities in reducing blood glucose levels in diabetes mellitus sufferers. Method: The research design used a descriptive method with a nursing process approach with a case study design. This research was carried out by providing foot exercise physical activity intervention for 3 consecutive days. Results: Based on the application of EBP, the results obtained from 3 patients who experienced a decrease in blood glucose levels before and after being given foot exercise therapy, there was an average decrease in P1 of 13.66mg/dL, P2 of 11.66mg/dL, and P3 of 13mg/dL every day. Suggestion: It is hoped that the results of this research can provide insight to diabetes mellitus sufferers in efforts to manage diabetes mellitus with foot exercise physical activity and be able to apply it.

Cardiac Troponin1 (cTn1) is a protein released into the bloodstream following cardiac damage and Brain Natriuretic Peptide (BNP) is a hormone released by the heart in response to ventricular stretch and pressure overload. This study aims to investigate the predictive role of cTn1 and BNP in preeclamptic pregnant women in the third trimester of pregnancy. Forty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. Blood samples was spun in a bucket centrifuge at 2500 RPM (rounds per minute) for 10 minutes after which plasma was collected and stored frozen in plain sample bottles and was analyzed for Cardiac Troponin 1(cTn1) and Brain Natriuretic Peptide (BNP) by fluorescence immunoassay. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant.  The present study showed that there was statistically significant increase in Brain Natriuretic Peptide (BNP) in preeclamptic women compared to normotensive pregnant women, indicating various underlying pathophysiological processes. These findings suggest the potential predictive roles of this cardiac marker in identifying and monitoring preeclampsia.

This research was motivated by the researcher's curiosity about the poetry of Taufiq Ismail, he is known as a poet of demonstration poetry. The poem with the title "A Jacket Stained With Blood" has a unique choice of words and the symbols contained in the poem that are interesting to study in order to obtain a complete meaning. The formulation of the problem that researchers analyze in this research is what is the inner structure and physical structure embedded in the poem? The aim of this research is to describe the inner structure, namely theme, tone and feeling, atmosphere, and message. By focusing on analyzing the structure of the inner content of the poem concretely and clearly. The method prepared by the researcher is descriptive qualitative. As for the results obtained regarding the researcher's analysis, it can be concluded that this poem is a poem that has many types based on various points of view of the meaning contained in various types of poetry. This poem is an elegiac poem because it expresses feelings of sadness and contains the poet's lamentations.

Liberal Islamic philosophy is a contemporary concept within the Islamic world, arising as a counter to the prevailing association of Islam with radicalism, terrorism, and bloodshed. This new philosophy has a more lenient stance towards Islam's normative beliefs, aiming to engage with the perspectives of orthodox or fundamentalist Islamic organizations. This has provoked both favorable and adverse reactions to the theory. This page aims to portray liberal Islamic thinking academically and objectively, without taking a side in the controversies. The discourse encompasses the concept, aims, and epistemological framework of liberal Islam. The importance of this study stems from the perspectives of observers of Islamic thinking who either support or oppose liberal Islamic philosophy without offering a comprehensive comprehension of its fundamental notions.

In Article 338 of the Criminal Code, the element of taking a life is formulated as een ander van het leven beroven which means "taking another person's life". Because the act or behavior of taking another person's life does not always contain an element of violence, whereas if the word oven is translated with the word plunder then the act must be carried out with violence. The research method used in this thesis is juridical-empirical. Juridical-empirical research is legal research regarding the application or implementation of normative legal provisions directly to each specific legal event that occurs in society. Data collection methods are techniques or methods that can be used by researchers to collect data. The technique of designating a word that is abstract and not manifested in objects, but its use can only be seen through: questionnaires, interviews, observations, exams (tests), documentation, etc. Based on the research results, in case 200/Pid.B/2023/PN Kabanjahe, the application of Article 338 of the Criminal Code (KUHP) as a basis for assessing the crime of murder has a number of aspects that need to be studied in depth. The Public Prosecutor charged the Defendant with many articles, starting from Article 170 paragraph (2) 3e of the Criminal Code to Article 55 paragraph (1) 1st of the Criminal Code. This shows the prosecutor's efforts to cover all actions carried out by the Defendant. However, the main focus should be on premeditated murder, which is regulated in Article 340 of the Criminal Code.  In case 200/Pid.B/2023/PN Kabanjahe, the defendant Melina Simanjuntak alias Mamak Rani alias Ina Juntak was found guilty of committing the crime of murder accompanied by theft based on Article 339 of the Criminal Code in conjunction with Article 55 paragraph (1) 1st of the Criminal Code. The Panel of Judges considered a number of legal facts revealed during the trial, including the Defendant's direct involvement in the criminal acts committed with Jamando Sipayung. The use of strong evidence, such as bloodstains and valuables belonging to the victim, further strengthens the charges. Therefore, the Defendant was sentenced to prison for 15 years, with the period of detention already served being deducted from the sentence. Based on the research that has been carried out, it can be concluded that in case 200/Pid.B/2023/PN Kbj, the application of the elements The crime of murder as regulated in Article 338 of the Criminal Code has been carried out carefully. Apart from that, the consideration of the Panel of Judges in handing down sentences against perpetrators also reflects justice. The judge considers the background of the case, the perpetrator's motivation based on hurt feelings, and the impact of the act on the victim and his family

The purpose of the current study was to look into the connection between hair loss in thefirst and second trimesters of pregnancy and the levels of vitamin D3 and ferritin in bloodserum of pregnant at Tikrit Hospital. The participants in the study varied in age from 22to 38 years old, and the sample consisted of 50 pregnant women experiencing hair loss inthe first and second trimesters of their pregnancy. A comparison group consisted of 30pregnant women who did not experience hair loss. Every research participant had theirserum levels of ferritin, vitamin D3, white blood cell counts, and platelet counts tested.When compared to women who did not experience hair loss during the first and secondtrimesters of pregnancy, Vitamin D3& ferritin levels were found to be significantlyreduced in women who experienced hair loss throughout the first and second trimestersof pregnancy, compared to normal levels in woman who did not associated with hair lossbut rather their variations were explained by the typical physiology of pregnancy .

Inheritance law is a provision that regulates matters of property. If it is not regulated in detail, this will result in disputes within the family, even disputes will have very fatal consequences, even bloodshed between the family itself, sometimes because the influence of custom or law is still very strong. custom, namely by postponing the distribution of the heir's inheritance. To avoid this, rights are required that are recognized or granted by law and must also be attached to the person's responsibilities, if they are protected. Benefits or rights recognized or granted by law must also attach to the person's responsibilities. The method in this research is a qualitative method with a statutory approach and a conceptual approach where this writing examines statutory regulations and examines legal concepts contained in the articles contained in legal regulations, especially regarding the role of notaries in determining rights and responsibilities. the heir's responsibility from the perspective of Islamic law. In this case, the Notary has an important role in a will because they ensure its legality, validity and execution in accordance with the law. They help prevent inheritance from becoming available and ensure that the will's wishes are legally fulfilled.

The service activity carried out is in the form of a blood donation organized by the academic community of STIE Kalpataru Cibinong Bogor together with PMI Bogor Regency for the purpose of meeting the blood needs in Bogor Regency in particular, and in general it can also be used for other regions in Indonesia. This activity involves all parts of the academic community, including leaders, lecturers, staff and STIE Kalpataru students. PMI Bogor Regency appreciated this early activity very well, and they hope that this activity can be held routinely every year. This activity is intended as part of caring for others and an effort to uphold human solidarity.

Introduction : Central Line Associated Blood Stream Infection (CLABSI) or phlebitis is defined by the CDC as a bloodstream infection confirmed by laboratory results that occurs within 48 hours before developing into bacteremia, and is not associated with infection in other parts. Some research results conclude that several factors influence the occurrence of phlebitis, one of which is the selection of the insertion site. Purpose: to determine the effect of the insertion location of the infusion on the incidence of phlebitis. Design: Literature review method using Google Scholar and the Portal Garuda as database  (2018-2022). Method : keywords "location of infusion and phlebitis incident". Results: From 14 reviewed articles, it was found that the incidence of phlebitis due to insertion site factors was influenced by the selection of the vein, the distance between the infusion site and the joint and the selection of the dominant extremity (which is often used for activities). Conclusion: Infusion is done by selecting a good vein, choose a vein that is far from the joint (minimum > 3.5 cm distance from the joint), Avoid choosing a vein in the location or extremity dominant to minimize the movement of the intravenous catheter when the patient moves.